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"description": "Comment évaluer l'efficacité de la colle de fibrine ?\nQuels tests sont utilisés avant l'application ?\nY a-t-il des contre-indications à son utilisation ?\nComment détecter une réaction allergique ?\nQuels signes indiquent une mauvaise cicatrisation ?",
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"@type": "Question",
"name": "Comment évaluer l'efficacité de la colle de fibrine ?",
"position": 1,
"acceptedAnswer": {
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"text": "L'efficacité est évaluée par l'observation de la cicatrisation et la réduction des hémorragies."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés avant l'application ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de coagulation sanguine peuvent être réalisés pour évaluer la compatibilité."
}
},
{
"@type": "Question",
"name": "Y a-t-il des contre-indications à son utilisation ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les allergies aux composants de la colle ou des troubles de la coagulation sont des contre-indications."
}
},
{
"@type": "Question",
"name": "Comment détecter une réaction allergique ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une réaction allergique peut se manifester par des rougeurs, démangeaisons ou gonflements au site d'application."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent une mauvaise cicatrisation ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes comme une inflammation persistante, une déhiscence ou une infection peuvent indiquer une mauvaise cicatrisation."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent apparaître après l'application ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des rougeurs, gonflements ou douleurs au site d'application peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment reconnaître une infection post-opératoire ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une infection peut se manifester par une chaleur, une douleur accrue, ou un écoulement purulent."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires fréquents ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les effets secondaires peuvent inclure des démangeaisons ou des réactions au site d'application."
}
},
{
"@type": "Question",
"name": "Quels signes d'allergie doivent alerter ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme des éruptions cutanées, des démangeaisons ou un œdème peuvent indiquer une allergie."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des douleurs persistantes ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des douleurs persistantes peuvent survenir, nécessitant une évaluation médicale."
}
},
{
"@type": "Question",
"name": "Comment prévenir les infections après application ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maintenir une bonne hygiène et suivre les instructions post-opératoires aide à prévenir les infections."
}
},
{
"@type": "Question",
"name": "Quelles précautions prendre avant l'application ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Évaluer les allergies et les antécédents médicaux est essentiel avant l'application."
}
},
{
"@type": "Question",
"name": "Comment éviter les réactions allergiques ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un test cutané préalable peut aider à identifier les allergies potentielles aux composants."
}
},
{
"@type": "Question",
"name": "Y a-t-il des recommandations pour les patients ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les patients doivent suivre les conseils médicaux et signaler tout symptôme inhabituel."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque doivent être surveillés ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents d'allergies et les troubles de la coagulation sont des facteurs de risque importants."
}
},
{
"@type": "Question",
"name": "Comment la colle de fibrine est-elle appliquée ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est généralement appliquée par pulvérisation ou en gouttes sur les tissus à unir."
}
},
{
"@type": "Question",
"name": "Quels types de blessures peuvent être traités ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est utilisée pour des coupures, des incisions chirurgicales ou des lésions cutanées."
}
},
{
"@type": "Question",
"name": "La colle de fibrine remplace-t-elle les sutures ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut remplacer les sutures dans certains cas, mais n'est pas toujours appropriée."
}
},
{
"@type": "Question",
"name": "Quels soins sont nécessaires après application ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est important de garder la zone propre et sèche, et de surveiller les signes d'infection."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser la colle de fibrine en cas d'infection ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, son utilisation est contre-indiquée en présence d'une infection active."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme des infections, des réactions allergiques ou une mauvaise cicatrisation peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment gérer une réaction allergique ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "En cas de réaction allergique, il est crucial de consulter un médecin immédiatement."
}
},
{
"@type": "Question",
"name": "Quels signes d'infection nécessitent une attention médicale ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des rougeurs, chaleur, douleur accrue ou écoulement purulent nécessitent une attention médicale."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des cicatrices après utilisation ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des cicatrices peuvent se former, surtout si la cicatrisation est compromise."
}
},
{
"@type": "Question",
"name": "Quelles sont les conséquences d'une mauvaise application ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une mauvaise application peut entraîner des déhiscences, infections ou cicatrisation inadéquate."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les allergies, les troubles de la coagulation et les infections antérieures sont des facteurs de risque."
}
},
{
"@type": "Question",
"name": "Les personnes âgées sont-elles plus à risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes âgées peuvent avoir un risque accru de complications lors de l'utilisation."
}
},
{
"@type": "Question",
"name": "Les maladies chroniques influencent-elles le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des maladies comme le diabète peuvent augmenter le risque d'infection et de mauvaise cicatrisation."
}
},
{
"@type": "Question",
"name": "Comment le tabagisme affecte-t-il le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme peut retarder la cicatrisation et augmenter le risque d'infections."
}
},
{
"@type": "Question",
"name": "Les antécédents chirurgicaux augmentent-ils le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents de complications chirurgicales peuvent augmenter le risque lors de nouvelles interventions."
}
}
]
}
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Skin cancer is a common disease in the tropics, and oncological resection typically requires reconstruction with skin grafts. Fibrin glue, initially established as a haemostatic agent, has been studie...
The study design is a prospective randomised controlled trial with the aim of investigating the impact of two different methods of split skin graft fixation. The intervention of fibrin glue will be co...
The study has been approved by The Townsville University Hospital Human Research Ethics Committee. Findings will be disseminated in conference presentations and journals and through online electronic ...
ACTRN12618000484246....
We assessed quality of life (QoL) of patients undergoing surgery for proximal femur fracture and performed a cost-effectiveness analysis of haemostatic drugs for reducing postoperative bleeding....
We analysed data from an open, multicentre, parallel, randomized controlled clinical trial (RCT) that assessed the efficacy and safety of tranexamic acid (TXA group) and fibrin glue (FG group) adminis...
We included 134 consecutive patients from February 2013 to March 2015: 42 patients in the TXA group, 46 in the FG group, and 46 in the control group. Before the fracture, EuroQol visual analogue scale...
There were no significant differences between the intervention groups in terms of postoperative changes in QoL. However, topical TXA was more cost-effective than FG or usual haemostasis....
ClinicalTrials.gov: NCT02150720. Date of registration 30/05/2014. Retrospectively registered....
Commercial fibrin glue is increasingly finding its way into clinical practice in surgeries to seal anastomosis, and initiate hemostasis or tissue repair. Human biological glue is also being discussed ...
Collagen-based dermal regeneration matrices (DRM) were seeded with human umbilical vein endothelial cells (HUVEC), human dermal lymphatic endothelial cells (LECs), or adipose-derived stem cells (ASC) ...
All cell types reacted to fibrin glue application with an alteration of gene and protein expression. In particular, vascular endothelial growth factor A (VEGFA), vascular endothelial growth factor B (...
Our findings demonstrate the impact of fibrin glue application in dermal regeneration with special regard to angiogenesis and lymphangiogenesis. In particular, a short fibrin treatment of 24 hours led...
Chemotherapy has had disappointing results in the treatment of glioblastoma multiforme (GBM). This is in part due to limited systemic drug penetration through the blood-brain barrier. This limitation ...
FG layers, loaded with drug and photosensitizer, were formed in wells of a 24-well plate. Supernatants covering the FG layers were harvested after 48 h. F98 glioma spheroids were co-incubated with har...
100% of the drug bleomycin and 90% of the photosensitizer (AlPcS...
The results demonstrate that both drug and photosensitizer were loaded into and released in a non-degraded form for an extended time period. The growth inhibition caused by FG-released BLM was signifi...
Erythrocytes are deformable cells that undergo progressive biophysical and biochemical changes affecting the normal blood flow. Fibrinogen, one of the most abundant plasma proteins, is a primary deter...
Fibrin sealants are well-established components of the surgical toolbox, especially in procedures that harbor a high risk of perioperative bleeding. Their widespread use as hemostats, sealants or tiss...
The aim of this study was to compare the use of fibrin glue on the corneal epitheliectomy site at the end of pterygium surgery versus conventional eye patch regarding pain levels, need for oral analge...
Forty-eight eyes of 24 patients with bilateral primary pterygium were included in this prospective, randomized, double-masked controlled trial. Each eye of the same patient was randomized to the inter...
Visual analog pain scale after surgery was significantly lower in eyes receiving fibrin glue (-1.58; 95% confidence interval: -2.84 to -0.32; P = 0.014). In addition, the intervention group presented ...
Fibrin glue at the end of pterygium surgery effectively reduces pain and the need for oral analgesics compared with conventional eye patching. This study is the first to describe the results of this s...
A stable adhesion to the cartilage is a crucial requisite for hydrogels used for cartilage regeneration. Indeed, a weak interface between the tissue and the implanted material may produce a premature ...
CSF-to-venous fistulas contribute to spontaneous intracranial hypotension. CT-guided fibrin occlusion has been described as a minimally invasive treatment strategy; however, its reproducibility across...
A retrospective evaluation was conducted on CT-guided fibrin glue treatment in patients with CSF-to-venous fistulas from 6 US and UK institutions from 2020 to 2023. Patient information, procedural cha...
Of 119 patients at a mean follow-up of 5.0 months, fibrin occlusion resulted in complete clinical improvement in 59.7%, partial improvement in 34.5%, and no improvement in 5.9% of patients. Complicati...
Fibrin occlusion performed across various institutions shows cure when associated with injectate spread matching the CVF drainage pattern and shorter pretreatment symptom duration, emphasizing the imp...
Due to the extreme immaturity of many internal organs, including lungs, infants at the limit of viability are more predisposed to a pneumothorax (PTX). In some cases, PTX becomes persistent. Previousl...
We present a case of an extremely preterm infant with persistent PTX who was successfully treated with fibrin glue. In addition, we present a two-and-a-half-year corrected age follow-up focusing on re...
Fibrin glue should be used to treat persistent PTX even in an extremely preterm infant. No adverse effects were observed. At the two-and-a-half-year corrected age follow-up, despite severe bronchopulm...