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"name": "Comment diagnostique-t-on la vaginose bactérienne ?",
"position": 1,
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"text": "Le diagnostic repose sur l'examen clinique et des tests de pH vaginal et de sécrétions."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour confirmer la vaginose ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests comme l'examen microscopique et le test de l'amine peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "Les symptômes sont-ils suffisants pour le diagnostic ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, les symptômes doivent être corroborés par des tests de laboratoire pour un diagnostic précis."
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"@type": "Question",
"name": "Peut-on confondre la vaginose avec d'autres infections ?",
"position": 4,
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"@type": "Answer",
"text": "Oui, elle peut être confondue avec des infections comme la candidose ou les IST."
}
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{
"@type": "Question",
"name": "Quel rôle joue le pH vaginal dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
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"text": "Un pH vaginal supérieur à 4,5 est souvent un indicateur de vaginose bactérienne."
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{
"@type": "Question",
"name": "Quels sont les symptômes courants de la vaginose ?",
"position": 6,
"acceptedAnswer": {
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"text": "Les symptômes incluent des pertes vaginales anormales, une odeur forte et des démangeaisons."
}
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{
"@type": "Question",
"name": "La vaginose peut-elle être asymptomatique ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines femmes peuvent ne présenter aucun symptôme malgré la présence de l'infection."
}
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{
"@type": "Question",
"name": "Comment décrire l'odeur associée à la vaginose ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'odeur est souvent décrite comme un parfum de poisson, surtout après les rapports sexuels."
}
},
{
"@type": "Question",
"name": "Les pertes vaginales sont-elles toujours présentes ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, certaines femmes peuvent avoir des pertes minimes ou absentes malgré l'infection."
}
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{
"@type": "Question",
"name": "Les symptômes peuvent-ils varier d'une personne à l'autre ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'intensité et la nature des symptômes peuvent varier considérablement entre les femmes."
}
},
{
"@type": "Question",
"name": "Comment prévenir la vaginose bactérienne ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maintenir une bonne hygiène vaginale et éviter les douches vaginales peut aider à prévenir."
}
},
{
"@type": "Question",
"name": "Les rapports sexuels affectent-ils le risque de vaginose ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, avoir de nouveaux partenaires sexuels ou des rapports non protégés peut augmenter le risque."
}
},
{
"@type": "Question",
"name": "Les probiotiques peuvent-ils aider à prévenir la vaginose ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent que les probiotiques peuvent aider à rétablir l'équilibre vaginal."
}
},
{
"@type": "Question",
"name": "Le tabagisme influence-t-il le risque de vaginose ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme est associé à un risque accru de vaginose bactérienne."
}
},
{
"@type": "Question",
"name": "Les vêtements peuvent-ils affecter la santé vaginale ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, porter des vêtements serrés ou en matières synthétiques peut favoriser la vaginose."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour la vaginose ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antibiotiques comme le métronidazole ou la clindamycine sont couramment prescrits."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils efficaces à 100 % ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Bien que souvent efficaces, il existe un risque de récidive après le traitement."
}
},
{
"@type": "Question",
"name": "Peut-on traiter la vaginose avec des remèdes naturels ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines femmes essaient des remèdes naturels, mais leur efficacité n'est pas prouvée scientifiquement."
}
},
{
"@type": "Question",
"name": "Faut-il traiter la vaginose si elle est asymptomatique ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement est recommandé même sans symptômes, surtout avant une intervention chirurgicale."
}
},
{
"@type": "Question",
"name": "Les partenaires doivent-ils être traités ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "En général, le traitement des partenaires n'est pas nécessaire, sauf en cas de symptômes."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec la vaginose ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent un risque accru d'infections sexuellement transmissibles et de complications pendant la grossesse."
}
},
{
"@type": "Question",
"name": "La vaginose peut-elle affecter la fertilité ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Bien que rare, une vaginose non traitée peut contribuer à des problèmes de fertilité."
}
},
{
"@type": "Question",
"name": "Y a-t-il un lien entre vaginose et grossesse ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la vaginose peut augmenter le risque de complications pendant la grossesse, comme l'accouchement prématuré."
}
},
{
"@type": "Question",
"name": "Les infections urinaires sont-elles liées à la vaginose ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les femmes atteintes de vaginose peuvent avoir un risque accru d'infections urinaires."
}
},
{
"@type": "Question",
"name": "La vaginose peut-elle causer des douleurs pelviennes ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Bien que rare, certaines femmes peuvent ressentir des douleurs pelviennes en raison de la vaginose."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque de vaginose ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des changements hormonaux, des rapports sexuels fréquents et le tabagisme."
}
},
{
"@type": "Question",
"name": "L'utilisation de contraceptifs affecte-t-elle le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains contraceptifs hormonaux peuvent influencer le déséquilibre bactérien vaginal."
}
},
{
"@type": "Question",
"name": "Les antécédents d'infections vaginales augmentent-ils le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les femmes ayant des antécédents d'infections vaginales sont plus susceptibles de développer une vaginose."
}
},
{
"@type": "Question",
"name": "Le stress peut-il influencer la vaginose ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut affecter le système immunitaire et augmenter le risque d'infections vaginales."
}
},
{
"@type": "Question",
"name": "Les changements alimentaires jouent-ils un rôle ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation déséquilibrée peut affecter la flore vaginale et augmenter le risque de vaginose."
}
}
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The female genital ulcer is a manifestation of many diseases, which may vary depending on the etiology, disease duration, age, and host immunity. A middle-aged (40-50 years) woman had a 4-month histor...
The goal of this study was to assess the acceptability of a single-dose bioadhesive 2% clindamycin vaginal gel for bacterial vaginosis (BV)....
This double-blind, placebo-controlled, randomized study compared a new clindamycin gel with placebo gel (2:1 ratio). The primary objective was efficacy; secondary objectives were safety and acceptabil...
A total of 307 women with BV were randomized to treatment (204 to the clindamycin gel group and 103 to the placebo gel group). Most (88.3%) reported at least one previously diagnosed BV episode, and m...
A single dose of a new bioadhesive 2% clindamycin vaginal gel showed rapid resolution of symptoms and was highly acceptable as a treatment for bacterial vaginosis....
gov identifier: NCT04370548....
Bacterial vaginosis (BV) is the most common vaginal dysbiosis among women of reproductive age. Micronutrient deficiencies, including vitamin D deficiency, can increase the risk of BV. The findings of ...
This case-control study was conducted in Gonabad County in 2021. One hundred and twenty-five confirmed BV cases and 125 controls who were matched based on age and intercourse frequency (maximum differ...
The BV cases had significantly lower 25-hydroxy vitamin D serum levels than controls. The odds of BV increased with vitamin D deficiency (Adjusted odds ratio (AOR): 4.34, 95% confidence interval (CI):...
These findings suggested that lower serum vitamin D levels were associated with an increased risk of developing BV. However, further studies are needed to confirm the results of the present study....
Bacterial vaginosis (BV) is a common cause of vaginal infection. First-line treatments of BV are metronidazole and clindamycin. Due to the increase in antibiotic resistance, effective nonantibiotic tr...
To examine whether dequalinium chloride, a broad-spectrum antiseptic, is noninferior to oral metronidazole for the treatment of BV....
This phase 4, multicenter, triple-blind, double-dummy, parallel, noninferiority randomized clinical trial was conducted from July 29, 2021, to August 25, 2022, with a 1-month follow-up. Participants w...
Patients were randomized to treatment with dequalinium chloride vaginal tablets (10 mg once daily for 6 days) or oral metronidazole (500 mg twice daily for 7 days). Double-dummy medication kits contai...
The main outcome was the noninferiority margin (of 15 percentage points) in the absolute difference in clinical cure rates between dequalinium chloride and metronidazole 7 to 11 days after start of tr...
A total of 147 women (mean [SD] age, 36.7 [9.0] years) were treated with dequalinium chloride (n = 72) or metronidazole (n = 75). The clinical cure rates at visit 1 were 64 of 69 (92.8%) for dequalini...
This randomized clinical trial showed that dequalinium chloride was not inferior to metronidazole for the treatment of BV. Dequalinium chloride had a similarly high cure rate but with better tolerabil...
EudraCT: 2020-002489-15....
There is an unmet need for a clinical diagnostic technology to detect bacterial vaginosis (BV) rapidly and accurately. Novel point-of-care (POC) tests have the potential to fulfill this gap. Our objec...
We developed a state-transition microsimulation model to evaluate the cost-effectiveness of using the POC test versus usual care among women of reproductive age with vaginal symptoms. We adopted a hea...
Using the hypothetical POC test to diagnose BV increased costs by $16 and quality-adjusted life-years by 0.0005 per person compared with the usual care, leading to an incremental cost-effectiveness ra...
Using the POC test to diagnose BV is likely to be cost-effective relative to usual care, especially with a high sensitivity or a substantial positive effect on productivity....
Bacterial vaginosis (BV) is one of the most common vaginal infectious diseases in female reproductive period. Although the existing view is that probiotic treatment may be one of the feasible methods ...
This meta-analysis aims to systematically evaluate the role of probiotics in the treatment of BV in adult women....
We searched the databases of Embase, Cochrane Library, PubMed, Web of Science and ClinicalTrials.gov for Randomized Controlled Trials published until November 7, 2021. Meta-analysis was performed by R...
Fourteen randomized controlled trials compared the efficacy of probiotics with antibiotic therapy (probiotics + antibiotics group) versus antibiotics alone or plus placebo (antibiotics (+ placebo) gro...
Our meta-analysis suggests probiotics may play a positive role in the treatment of BV, but more strong evidence is needed....
Despite more than 60 years of research, the etiology of bacterial vaginosis (BV) remains controversial. In this pilot study, we used shotgun metagenomic sequencing to characterize vaginal microbial co...
A cohort of African American women with a baseline healthy vaginal microbiome (no Amsel criteria, Nugent score 0-3 with no Gardnerella vaginalis morphotypes) were followed for 90 days with daily self-...
Common BV-associated bacteria such as G. vaginalis , Prevotella bivia , and Fannyhessea vaginae were increasingly identified in the participants before iBV. Linear modeling indicated significant incre...
This pilot study characterizes vaginal community dynamics before iBV and identifies key bacterial taxa and mechanisms potentially involved in the pathogenesis of iBV....
Women of childbearing age are commonly affected by bacterial vaginosis (BV). Maternal-fetal outcomes associated with BV during pregnancy can be fatal for both the mother and the newborn....
To identify maternal and fetal outcomes in pregnant women with BV encountered globally, highlight their prevalence, and identify maternal-fetal outcomes associated with BV....
The databases Embase, PubMed, Web of Science and Global Index Medicus were searched from inception until December 2022. No restrictions on time or geographical location were imposed when searching for...
In total, 26 of the 8983 articles retrieved from the databases met the inclusion criteria and were included in this study. Twenty-two maternal outcomes and 22 fetal outcomes were recorded among pregna...
BV has been associated with several adverse maternal-fetal outcomes around the world. While BV is a common vaginal infection, the types of maternal-fetal outcomes from pregnant women with BV vary by c...
To assess efficacy and safety of a single-dose vaginal clindamycin gel for bacterial vaginosis treatment....
We conducted a double-blind, placebo-controlled, randomized study comparing clindamycin gel with placebo (2:1 ratio). Entry required clinical diagnosis of bacterial vaginosis, that is, all four Amsel'...
Participants were seen between July 9, 2020, and November 12, 2020. Of 307 randomized women, 56.0% were Black and 88.3% reported one or more previous bacterial vaginosis episodes. In the modified inte...
A new, single-dose clindamycin vaginal gel was highly effective, with excellent safety, in women disproportionately affected by bacterial vaginosis, with Nugent scores of 7-10 at study entry....
The study was funded by Daré Bioscience, Inc....
ClinicalTrials.gov, NCT04370548....
This study was undertaken to determine the prevalence of Bacterial Vaginosis (BV), Trichomonas Vaginalis (TV) co-infection, and the antibacterial sensitivity profile of bacterial isolates....
The study was a cross-sectional study of 232 pregnant women on a routine antenatal visit between April 2019 and Sept. 2020, at Amukoko clinic in Lagos, Nigeria. The gynaecologist conducted the clinica...
The mean age of the clients was 28.11 ± 7.08 years of age. The majority (88%) were aged 15-35 years. Only 81 (34.9%) had microbial organisms isolated or seen from their specimens and 19 (8.2%) of such...
There is a relatively low prevalence of BV and flagellate co-infection in the community studied....
We recommend screening of antenatal women with underlying symptoms for BV and flagellates co-infection to avoid its progression to vaginitis....