Titre : Syndrome des anticorps antiphospholipides

Syndrome des anticorps antiphospholipides : Questions médicales fréquentes

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diagnostic ?\nQuels critères sont utilisés pour le diagnostic ?\nLe diagnostic nécessite-t-il des symptômes cliniques ?\nPeut-on avoir le syndrome sans symptômes ?", "url": "https://questionsmedicales.fr/mesh/D016736?page=2#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Syndrome des anticorps antiphospholipides", "description": "Quels sont les symptômes courants du syndrome ?\nLe syndrome peut-il causer des douleurs ?\nY a-t-il des symptômes neurologiques associés ?\nLes symptômes varient-ils d'une personne à l'autre ?\nLe syndrome affecte-t-il la grossesse ?", "url": "https://questionsmedicales.fr/mesh/D016736?page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Syndrome des anticorps antiphospholipides", "description": "Comment prévenir les complications du syndrome ?\nY a-t-il des changements de mode de vie recommandés ?\nLes femmes enceintes doivent-elles être surveillées 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le risque de cancer ?", "url": "https://questionsmedicales.fr/mesh/D016736?page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Syndrome des anticorps antiphospholipides", "description": "Quels sont les facteurs de risque du syndrome ?\nLe sexe influence-t-il le risque ?\nLes antécédents de thromboses augmentent-ils le risque ?\nLes infections virales sont-elles un facteur de risque ?\nLe tabagisme influence-t-il le risque ?", "url": "https://questionsmedicales.fr/mesh/D016736?page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostique-t-on le syndrome des anticorps antiphospholipides ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic repose sur des tests sanguins pour détecter les anticorps antiphospholipides." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour le diagnostic ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests incluent le lupus anticoagulant, les anticorps anti-cardiolipine et anti-bêta-2-glycoprotéine I." } }, { "@type": "Question", "name": "Quels critères sont utilisés pour le diagnostic ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Les critères incluent des antécédents de thromboses et la présence d'anticorps spécifiques." } }, { "@type": "Question", "name": "Le diagnostic nécessite-t-il des symptômes cliniques ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents de thromboses ou de complications obstétricales sont souvent requis." } }, { "@type": "Question", "name": "Peut-on avoir le syndrome sans symptômes ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines personnes peuvent avoir des anticorps sans présenter de symptômes cliniques." } }, { "@type": "Question", "name": "Quels sont les symptômes courants du syndrome ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent des thromboses, des fausses couches et des éruptions cutanées." } }, { "@type": "Question", "name": "Le syndrome peut-il causer des douleurs ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des douleurs peuvent survenir en raison de thromboses dans les vaisseaux sanguins." } }, { "@type": "Question", "name": "Y a-t-il des symptômes neurologiques associés ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des symptômes comme des maux de tête, des AVC ou des troubles cognitifs peuvent apparaître." } }, { "@type": "Question", "name": "Les symptômes varient-ils d'une personne à l'autre ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'intensité et la nature des symptômes peuvent varier considérablement entre les individus." } }, { "@type": "Question", "name": "Le syndrome affecte-t-il la grossesse ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, il peut entraîner des complications comme des fausses couches ou des prééclampsies." } }, { "@type": "Question", "name": "Comment prévenir les complications du syndrome ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention inclut la prise régulière d'anticoagulants et le suivi médical." } }, { "@type": "Question", "name": "Y a-t-il des changements de mode de vie recommandés ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, maintenir un poids santé, faire de l'exercice et éviter le tabac sont conseillés." } }, { "@type": "Question", "name": "Les femmes enceintes doivent-elles être surveillées ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une surveillance étroite est essentielle pour prévenir les complications obstétricales." } }, { "@type": "Question", "name": "Les vaccinations sont-elles importantes ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les vaccinations peuvent aider à prévenir certaines infections qui aggravent le syndrome." } }, { "@type": "Question", "name": "Le stress a-t-il un impact sur le syndrome ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Le stress peut exacerber les symptômes, donc des techniques de gestion du stress sont utiles." } }, { "@type": "Question", "name": "Quels traitements sont disponibles pour le syndrome ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des anticoagulants et des médicaments immunosuppresseurs." } }, { "@type": "Question", "name": "Les anticoagulants sont-ils efficaces ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les anticoagulants réduisent le risque de thromboses chez les patients atteints." } }, { "@type": "Question", "name": "Le traitement est-il à vie ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Pas toujours, mais de nombreux patients nécessitent un traitement à long terme." } }, { "@type": "Question", "name": "Y a-t-il des effets secondaires aux traitements ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les anticoagulants peuvent causer des saignements et d'autres effets indésirables." } }, { "@type": "Question", "name": "Les femmes enceintes peuvent-elles être traitées ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des anticoagulants comme l'héparine sont souvent utilisés pendant la grossesse." } }, { "@type": "Question", "name": "Quelles sont les complications possibles du syndrome ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des thromboses veineuses profondes, des AVC et des fausses couches." } }, { "@type": "Question", "name": "Le syndrome peut-il causer des problèmes cardiaques ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, il peut augmenter le risque de maladies cardiovasculaires et d'infarctus." } }, { "@type": "Question", "name": "Y a-t-il des risques pour la santé mentale ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des troubles anxieux et dépressifs peuvent survenir chez certains patients." } }, { "@type": "Question", "name": "Les complications sont-elles réversibles ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être gérées, mais d'autres peuvent avoir des effets durables." } }, { "@type": "Question", "name": "Le syndrome augmente-t-il le risque de cancer ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Des études suggèrent un lien possible, mais des recherches supplémentaires sont nécessaires." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque du syndrome ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des antécédents familiaux, des maladies auto-immunes et des infections." } }, { "@type": "Question", "name": "Le sexe influence-t-il le risque ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le syndrome est plus fréquent chez les femmes, surtout entre 20 et 40 ans." } }, { "@type": "Question", "name": "Les antécédents de thromboses augmentent-ils le risque ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, avoir des antécédents de thromboses augmente significativement le risque de syndrome." } }, { "@type": "Question", "name": "Les infections virales sont-elles un facteur de risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Certaines infections virales, comme le VIH, peuvent augmenter le risque de développer le syndrome." } }, { "@type": "Question", "name": "Le tabagisme influence-t-il le risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le tabagisme est associé à un risque accru de thromboses et de complications." } } ] } ] }

Sources (10000 au total)

Early recognition of catastrophic antiphospholipid syndrome in patients with antiphospholipid syndrome based on a Chinese cohort study.

Catastrophic antiphospholipid syndrome (CAPS) is a life-threatening form of antiphospholipid syndrome (APS) with high mortality. We try to develop a predictive model to achieve early recognition of CA... Data of APS patients referred into Peking Union Medical College Hospital from May 2013 to October 2021 was collected. A binary logistic regression method was used to identify predictors of CAPS, coeff... Twenty-seven CAPS (11.9%) occurred in 226 APS patients. CAPS was more likely to occur in male secondary APS patients with a history of hypertension, hyperlipidaemia, and arterial thrombosis, presented... A predictive model of CAPS was developed with hypertension, anaemia, elevated LDH and proteinuria. This model could help identify CAPS in high-risk patients, achieve early recognition and intervention...

A one-point increase in the Damage Index for Antiphospholipid Syndrome (DIAPS) predicts mortality in thrombotic antiphospholipid syndrome.

To determine whether early damage and its kinetics measured by the Damage Index for Antiphospholipid Syndrome (DIAPS) predicts mortality.... We carried out a single-centre retrospective analysis of thrombotic APS patients (2006 Sydney criteria), using the DIAPS for damage assessment. Early damage was considered to be at six months after di... A total of 197 patients (71.1% female; 65.9% primary APS; 72.4% Caucasian) were followed for up to 43 years (median 10). Damage developed in 143 (73.6%) patients. Twenty-three patients (12%) died. Sec... Evolving damage in the first five years of illness, but not early damage, predicted mortality regardless of the nature of the first thrombotic event, sex, APS category and age....

Neurologic Manifestations of Catastrophic Antiphospholipid Syndrome.

Understanding of antiphospholipid antibody syndrome (APS), associated neurological manifestations, and disease-directed treatment has grown considerably over the last decade. Herein, we critically rev... APS may manifest with a variety of neurologic syndromes, with cerebrovascular disease representing the most commonly encountered presentation. Diagnostic evaluation and treatment are often tailored to...

Pediatric antiphospholipid syndrome: is it the same as an adult?

Antiphospholipid syndrome in neonates and children is a rare, but in some cases life-threatening condition with arterial and/or venous thrombosis and/or non-thrombotic neurological, skin, ophthalmolog... This review highlights the available information about the features of pediatric APS, including the rare catastrophic form, the differences between pediatric and adult APS, and the role of genetic thr... The clinical manifestations and treatment options for APS in children may differ from those in adults, and prescribing therapy can be challenging due to the unique clinical and morphological character...

Prevalence and diagnostic value of non-criteria antiphospholipid antibodies for antiphospholipid syndrome in Chinese patients.

The presence of antiphospholipid antibodies (aPLs) plays a pivotal role in the pathogenesis of antiphospholipid antibody syndrome (APS). This study aimed to examine the diagnostic value of a set of no... From a prospectively constructed database, consecutive APS patients consisting of 114 primary APS (PAPS group), 54 with APS secondary to SLE (SAPS group), 9 seronegative APS (SNAPS), as well as 209 pa... The addition of aPC IgG/M, aPI IgG/M, aPE IgG/M/A, aSM IgG/M, and aPA IgG/M to aCL or aβ2GPI IgG/M could significantly increase diagnostic sensitivity and accuracy. A significant difference between PA... Additional detection of non-criteria aPLs including aPC IgG/M, aPE IgG/M/A, aPI IgG/M, aSM IgG/M, and aPA IgG/M could assist in APS diagnosis. The positivity of certain aPLs was statistically associat...