Titre : Infections à Ureaplasma

Infections à Ureaplasma : Questions médicales fréquentes

Termes MeSH sélectionnés :

Valosin Containing Protein
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?\nLes infections à Ureaplasma peuvent-elles être asymptomatiques ?", "url": "https://questionsmedicales.fr/mesh/D016869?mesh_terms=Valosin+Containing+Protein&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Infections à Ureaplasma", "description": "Comment prévenir les infections à Ureaplasma ?\nLes dépistages réguliers sont-ils utiles ?\nL'éducation sexuelle aide-t-elle à prévenir Ureaplasma ?\nLes pratiques sexuelles à risque augmentent-elles le risque ?\nLes infections urinaires augmentent-elles le risque d'Ureaplasma ?", "url": "https://questionsmedicales.fr/mesh/D016869?mesh_terms=Valosin+Containing+Protein&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Infections à Ureaplasma", "description": "Quel est le traitement standard pour Ureaplasma ?\nLes infections à Ureaplasma nécessitent-elles une hospitalisation ?\nCombien de temps dure le traitement ?\nLes partenaires doivent-ils être traités ?\nY a-t-il des effets secondaires aux antibiotiques ?", "url": "https://questionsmedicales.fr/mesh/D016869?mesh_terms=Valosin+Containing+Protein&page=2#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Infections à Ureaplasma", "description": "Quelles complications peuvent survenir avec Ureaplasma ?\nUreaplasma peut-il affecter la fertilité ?\nLes infections néonatales sont-elles possibles ?\nUreaplasma peut-il causer des maladies chroniques ?\nLes infections à Ureaplasma peuvent-elles réapparaître ?", "url": "https://questionsmedicales.fr/mesh/D016869?mesh_terms=Valosin+Containing+Protein&page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Infections à Ureaplasma", "description": "Quels sont les facteurs de risque d'infection à Ureaplasma ?\nLes femmes sont-elles plus à risque ?\nL'utilisation de contraceptifs hormonaux influence-t-elle le risque ?\nLes personnes immunodéprimées sont-elles plus vulnérables ?\nLes antécédents d'infections sexuellement transmissibles augmentent-ils le risque ?", "url": "https://questionsmedicales.fr/mesh/D016869?mesh_terms=Valosin+Containing+Protein&page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une infection à Ureaplasma ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic se fait par culture bactérienne ou PCR sur des échantillons urinaires ou génitaux." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour Ureaplasma ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests incluent la culture, la PCR et les tests sérologiques pour détecter les anticorps." } }, { "@type": "Question", "name": "Les symptômes aident-ils au diagnostic ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les symptômes cliniques peuvent orienter le diagnostic, mais des tests sont nécessaires." } }, { "@type": "Question", "name": "Les infections à Ureaplasma sont-elles asymptomatiques ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, de nombreuses infections à Ureaplasma peuvent être asymptomatiques, rendant le diagnostic difficile." } }, { "@type": "Question", "name": "Peut-on diagnostiquer Ureaplasma par un frottis ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Un frottis peut être utilisé, mais il est moins spécifique que la culture ou la PCR." } }, { "@type": "Question", "name": "Quels sont les symptômes courants d'une infection à Ureaplasma ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent des douleurs urinaires, des écoulements génitaux et des douleurs pelviennes." } }, { "@type": "Question", "name": "Les infections à Ureaplasma causent-elles des douleurs ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elles peuvent provoquer des douleurs lors de la miction ou des rapports sexuels." } }, { "@type": "Question", "name": "Y a-t-il des symptômes spécifiques chez les femmes ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Chez les femmes, des saignements vaginaux anormaux et des douleurs pelviennes peuvent survenir." } }, { "@type": "Question", "name": "Les hommes présentent-ils des symptômes ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les hommes peuvent avoir des douleurs testiculaires et des écoulements urétraux." } }, { "@type": "Question", "name": "Les infections à Ureaplasma peuvent-elles être asymptomatiques ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, de nombreux cas sont asymptomatiques, ce qui complique le diagnostic." } }, { "@type": "Question", "name": "Comment prévenir les infections à Ureaplasma ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention inclut l'utilisation de préservatifs et une bonne hygiène génitale." } }, { "@type": "Question", "name": "Les dépistages réguliers sont-ils utiles ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des dépistages réguliers peuvent aider à détecter les infections asymptomatiques." } }, { "@type": "Question", "name": "L'éducation sexuelle aide-t-elle à prévenir Ureaplasma ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'éducation sexuelle peut sensibiliser aux risques et aux méthodes de prévention." } }, { "@type": "Question", "name": "Les pratiques sexuelles à risque augmentent-elles le risque ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les pratiques sexuelles non protégées augmentent le risque d'infections à Ureaplasma." } }, { "@type": "Question", "name": "Les infections urinaires augmentent-elles le risque d'Ureaplasma ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les infections urinaires peuvent prédisposer à des infections à Ureaplasma." } }, { "@type": "Question", "name": "Quel est le traitement standard pour Ureaplasma ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement standard inclut des antibiotiques comme la doxycycline ou l'azithromycine." } }, { "@type": "Question", "name": "Les infections à Ureaplasma nécessitent-elles une hospitalisation ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Rarement, la plupart des infections peuvent être traitées en ambulatoire avec des antibiotiques." } }, { "@type": "Question", "name": "Combien de temps dure le traitement ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement dure généralement de 7 à 14 jours, selon la gravité de l'infection." } }, { "@type": "Question", "name": "Les partenaires doivent-ils être traités ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, il est recommandé que les partenaires sexuels soient également traités pour éviter la réinfection." } }, { "@type": "Question", "name": "Y a-t-il des effets secondaires aux antibiotiques ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des effets secondaires comme des nausées ou des diarrhées peuvent survenir avec les antibiotiques." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec Ureaplasma ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des infections pelviennes, des problèmes de fertilité et des infections néonatales." } }, { "@type": "Question", "name": "Ureaplasma peut-il affecter la fertilité ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des infections à Ureaplasma non traitées peuvent contribuer à des problèmes de fertilité." } }, { "@type": "Question", "name": "Les infections néonatales sont-elles possibles ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une mère infectée peut transmettre Ureaplasma à son nouveau-né lors de l'accouchement." } }, { "@type": "Question", "name": "Ureaplasma peut-il causer des maladies chroniques ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Des infections chroniques peuvent entraîner des douleurs pelviennes persistantes et d'autres complications." } }, { "@type": "Question", "name": "Les infections à Ureaplasma peuvent-elles réapparaître ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les infections peuvent réapparaître, surtout si les partenaires ne sont pas traités." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque d'infection à Ureaplasma ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des rapports sexuels non protégés, des antécédents d'infections urinaires et des partenaires multiples." } }, { "@type": "Question", "name": "Les femmes sont-elles plus à risque ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les femmes sont souvent plus à risque en raison de leur anatomie et de leur microbiote vaginal." } }, { "@type": "Question", "name": "L'utilisation de contraceptifs hormonaux influence-t-elle le risque ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains contraceptifs hormonaux peuvent modifier le microbiote vaginal et augmenter le risque." } }, { "@type": "Question", "name": "Les personnes immunodéprimées sont-elles plus vulnérables ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les personnes immunodéprimées ont un risque accru d'infections à Ureaplasma." } }, { "@type": "Question", "name": "Les antécédents d'infections sexuellement transmissibles augmentent-ils le risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents d'IST peuvent augmenter la susceptibilité aux infections à Ureaplasma." } } ] } ] }

Sources (10000 au total)

Clinical Classification of Variants in the Valosin-Containing Protein Gene Associated With Multisystem Proteinopathy.

Pathogenic variants in the valosin-containing protein (... A 6-item clinical score was developed to evaluate the phenotypic level of evidence to support the pathogenicity of the novel variants. Each item is allocated a value, a score ranging from 0.5 to 5.5 p... All variants were missense, except for one small deletion-insertion, 18 led to amino acid changes within the N and D1 domains, and 13 increased the enzymatic activity. The clinical score coincided wit... This study provides data to support pathogenicity of 14 of 19 novel...

Genotype-phenotype correlations in valosin-containing protein disease: a retrospective muticentre study.

Valosin-containing protein (VCP) disease, caused by mutations in the... Descriptive retrospective international study collecting clinical and genetic data of patients with mutations in the... Two hundred and fifty-five patients (70.0% males) were included in the study. Mean age was 56.8±9.6 years and mean age of onset 45.6±9.3 years. Mean diagnostic delay was 7.7±6 years. Symmetric lower l... This study expands the knowledge on the phenotypic presentation, natural history, genotype-phenotype correlations and risk factors for disease progression of VCP disease and is useful to improve the c...

Anti-Valosin-Containing Protein (VCP/p97) Autoantibodies in Inclusion Body Myositis and Other Inflammatory Myopathies.

The rationale for this study was based on reports that valosin-containing protein (VCP) mutations are found in hereditary inclusion body myositis (IBM) and VCP was detected in rimmed vacuoles of spora... Sera were collected from 73 patients with sIBM and 383 comparators or controls, including patients with IIM (n = 69), those with juvenile dermatomyositis (JDM) (n = 67), those with juvenile idiopathic... Among patients with sIBM, 26.0% (19/73) were positive for anti-VCP. The frequency in disease controls was 15.0% (48/320). Among SACs, the frequency was 1.6% (1/63), and in HCs 0% (0/32). Frequencies w... Anti-VCP has low sensitivity and moderate specificity for sIBM but may help fill the seronegative gap in sIBM. Further studies are needed to determine whether anti-VCP is a biomarker for a clinical ph...

Autoantibodies to nuclear valosin-containing protein-like protein: systemic sclerosis-specific antibodies revealed by in vitro human proteome.

To identify and characterize undescribed systemic sclerosis (SSc)-specific autoantibodies targeting nucleolar antigens and to assess their clinical significance.... We conducted proteome-wide autoantibody screening (PWAS) against serum samples from SSc patients with nucleolar patterned anti-nuclear antibodies (NUC-ANAs) of specific antibodies (Abs) unknown, utili... PWAS identified three candidate autoantibodies, including anti-nuclear valosin-containing protein-like (NVL) Ab. Additional measurements in disease controls revealed that only anti-NVL Abs are exclusi... Anti-NVL Ab is an SSc-specific autoantibody associated with a unique combination of clinical features, including limited skin sclerosis and lack of lung involvement....

Anti-nuclear valosin-containing protein-like autoantibody is associated with calcinosis and higher risk of cancer in systemic sclerosis.

Systemic sclerosis (SSc)-specific autoantibodies allow the diagnosis and predict the prognosis of SSc patients with different clinical characteristics. The aim of this study was to describe new SSc-re... Serum samples and clinical data were collected from 307 SSc patients. Antinuclear autoantibodies were tested in all patients by indirect immunofluorescence (IIF) on HEp-2 cells. SSc-specific autoantib... Five patients who underwent protein IP testing showed a 110-115kDa molecular weight band on SDS-PAGE and a homogeneous nucleolar pattern by IIF. MS identified the bands as nuclear valosin-containing p... We identified NVL as a new autoantibody target by a novel protein IP assay in SSc patients with a homogeneous nucleolar IIF pattern, testing negative for all known SSc-specific autoantibodies by comme...

Adaptor-Specific Antibody Fragment Inhibitors for the Intracellular Modulation of p97 (VCP) Protein-Protein Interactions.

Protein-protein interactions (PPIs) form complex networks to drive cellular signaling and cellular functions. Precise modulation of a target PPI helps explain the role of the PPI in cellular events an...