questionsmedicales.fr
Facteurs biologiques
Protéines et peptides de signalisation intercellulaire
Cytokines
Interleukines
Interleukine-9
Interleukine-9 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Tests de laboratoire
Interleukine-9
Interleukine-9
Inflammation
Symptômes
5
Asthme
Réactions allergiques
Interleukine-9
Hyperréactivité bronchique
Troubles gastro-intestinaux
Interleukine-9
Démangeaisons
Difficultés respiratoires
Prévention
5
Prévention des maladies
Allergènes
Éducation des patients
Allergies
Alimentation
Inflammation
Contrôle environnemental
Allergènes
Traitements
5
Antihistaminiques
Interleukine-9
Anticorps monoclonaux
Asthme
Corticostéroïdes
Interleukine-9
Bronchodilatateurs
Asthme
Immunothérapie
Interleukine-9
Complications
5
Exacerbations d'asthme
Réactions allergiques
Maladies auto-immunes
Interleukine-9
Surinfections
Interleukine-9
Complications pulmonaires
Fibrose
Troubles cardiovasculaires
Interleukine-9
Facteurs de risque
5
Antécédents familiaux
Asthme
Pollution de l'air
Interleukine-9
Infections respiratoires
Interleukine-9
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"@type": "Question",
"name": "Comment mesurer l'interleukine-9 ?",
"position": 1,
"acceptedAnswer": {
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"text": "L'IL-9 peut être mesurée par des tests ELISA dans le sérum ou les fluides biologiques."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins et des analyses de cytokines sont utilisés pour évaluer l'IL-9."
}
},
{
"@type": "Question",
"name": "L'IL-9 est-elle liée à des maladies spécifiques ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-9 est associée à des maladies comme l'asthme et certaines allergies."
}
},
{
"@type": "Question",
"name": "Quels biomarqueurs sont associés à l'IL-9 ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IL-9 est souvent mesurée avec d'autres cytokines comme l'IL-4 et l'IL-5."
}
},
{
"@type": "Question",
"name": "L'IL-9 peut-elle être un indicateur de gravité ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des niveaux élevés d'IL-9 peuvent indiquer une inflammation sévère."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont liés à l'IL-9 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des réactions allergiques, de l'asthme et des inflammations."
}
},
{
"@type": "Question",
"name": "L'IL-9 provoque-t-elle des symptômes respiratoires ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-9 est impliquée dans l'hyperréactivité bronchique et l'asthme."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes cutanés associés ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des éruptions cutanées peuvent survenir dans des conditions allergiques liées à l'IL-9."
}
},
{
"@type": "Question",
"name": "L'IL-9 est-elle liée à des symptômes gastro-intestinaux ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-9 peut être impliquée dans des troubles gastro-intestinaux allergiques."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques sont observés ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les signes incluent des difficultés respiratoires, des éruptions cutanées et des démangeaisons."
}
},
{
"@type": "Question",
"name": "Comment prévenir les maladies liées à l'IL-9 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les allergènes et adopter un mode de vie sain peut réduire les risques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des vaccins pour l'IL-9 ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de vaccins spécifiques pour cibler l'IL-9."
}
},
{
"@type": "Question",
"name": "L'éducation des patients est-elle importante ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, informer les patients sur les déclencheurs allergiques est essentiel pour la prévention."
}
},
{
"@type": "Question",
"name": "Les changements alimentaires peuvent-ils aider ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation équilibrée peut aider à réduire l'inflammation et les symptômes."
}
},
{
"@type": "Question",
"name": "Le contrôle de l'environnement est-il crucial ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, réduire l'exposition aux allergènes environnementaux est essentiel pour la prévention."
}
},
{
"@type": "Question",
"name": "Comment traiter les niveaux élevés d'IL-9 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des traitements anti-inflammatoires et des antihistaminiques peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "Y a-t-il des thérapies ciblées pour l'IL-9 ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anticorps monoclonaux ciblant l'IL-9 sont en développement pour traiter l'asthme."
}
},
{
"@type": "Question",
"name": "Les corticostéroïdes affectent-ils l'IL-9 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les corticostéroïdes peuvent réduire les niveaux d'IL-9 et l'inflammation associée."
}
},
{
"@type": "Question",
"name": "Quels médicaments sont utilisés pour l'asthme lié à l'IL-9 ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme les bronchodilatateurs et les corticostéroïdes sont couramment prescrits."
}
},
{
"@type": "Question",
"name": "L'immunothérapie aide-t-elle avec l'IL-9 ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'immunothérapie peut aider à moduler la réponse immunitaire liée à l'IL-9."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec l'IL-9 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des exacerbations d'asthme et des réactions allergiques sévères."
}
},
{
"@type": "Question",
"name": "L'IL-9 peut-elle aggraver d'autres maladies ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-9 peut exacerber des maladies auto-immunes et inflammatoires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de surinfection ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients avec des niveaux élevés d'IL-9 peuvent être à risque de surinfections."
}
},
{
"@type": "Question",
"name": "Des complications pulmonaires sont-elles possibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-9 peut contribuer à des complications pulmonaires comme la fibrose."
}
},
{
"@type": "Question",
"name": "L'IL-9 est-elle liée à des troubles cardiovasculaires ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des études suggèrent un lien entre l'IL-9 et des troubles cardiovasculaires, mais c'est encore à étudier."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour l'IL-9 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux d'allergies et d'asthme augmentent le risque d'IL-9 élevée."
}
},
{
"@type": "Question",
"name": "L'exposition à la pollution augmente-t-elle le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la pollution de l'air est un facteur de risque connu pour les maladies liées à l'IL-9."
}
},
{
"@type": "Question",
"name": "Le tabagisme influence-t-il l'IL-9 ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut augmenter les niveaux d'IL-9 et aggraver les symptômes respiratoires."
}
},
{
"@type": "Question",
"name": "Les infections respiratoires sont-elles un facteur ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les infections respiratoires peuvent déclencher une réponse immunitaire impliquant l'IL-9."
}
},
{
"@type": "Question",
"name": "Le stress a-t-il un impact sur l'IL-9 ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut exacerber les symptômes et augmenter les niveaux d'IL-9."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 30/03/2025
Contenu vérifié selon les dernières recommandations médicales
5 publications dans cette catégorie
Affiliations :
Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi 110029, India.
Publications dans "Interleukine-9" :
5 publications dans cette catégorie
Affiliations :
Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi 110029, India.
Publications dans "Interleukine-9" :
4 publications dans cette catégorie
Affiliations :
Philochem AG, CH-8112 Otelfingen, Switzerland.
Publications dans "Interleukine-9" :
4 publications dans cette catégorie
Affiliations :
Philochem AG, CH-8112 Otelfingen, Switzerland.
Publications dans "Interleukine-9" :
3 publications dans cette catégorie
Affiliations :
Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University, Heidelberg, Germany.
Publications dans "Interleukine-9" :
3 publications dans cette catégorie
Affiliations :
Department of Internal Medicine I, Univerisity Hospital Jena, 07747 Jena, Germany.
Publications dans "Interleukine-9" :
3 publications dans cette catégorie
Affiliations :
Division of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Publications dans "Interleukine-9" :
3 publications dans cette catégorie
Affiliations :
Department of Internal Medicine I, Univerisity Hospital Jena, 07747 Jena, Germany.
Publications dans "Interleukine-9" :
3 publications dans cette catégorie
Affiliations :
Department of Internal Medicine I, Univerisity Hospital Jena, 07747 Jena, Germany.
Publications dans "Interleukine-9" :
2 publications dans cette catégorie
Affiliations :
Microbiology, Immunology and Parasitology Department, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo, Brazil.
Publications dans "Interleukine-9" :
2 publications dans cette catégorie
Affiliations :
College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Institute of Comparative Medicine, Yangzhou University, Yangzhou, China.
Publications dans "Interleukine-9" :
2 publications dans cette catégorie
Affiliations :
College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Institute of Comparative Medicine, Yangzhou University, Yangzhou, China.
Publications dans "Interleukine-9" :
2 publications dans cette catégorie
Affiliations :
College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Institute of Comparative Medicine, Yangzhou University, Yangzhou, China.
Publications dans "Interleukine-9" :
2 publications dans cette catégorie
Affiliations :
College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Institute of Comparative Medicine, Yangzhou University, Yangzhou, China.
Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou, China.
International Corporation Laboratory of Agriculture and Agricultural Products Safety, Yangzhou University, Yangzhou, China.
Publications dans "Interleukine-9" :
2 publications dans cette catégorie
Affiliations :
Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi 110029, India.
Publications dans "Interleukine-9" :
2 publications dans cette catégorie
Affiliations :
Department of Rheumatology, All India Institute of Medical Sciences, New Delhi 110029, India.
Publications dans "Interleukine-9" :
2 publications dans cette catégorie
Affiliations :
Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi 110029, India.
Publications dans "Interleukine-9" :
2 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Publications dans "Interleukine-9" :
2 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Publications dans "Interleukine-9" :
2 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Brown Center for Immunotherapy, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Publications dans "Interleukine-9" :
To compare the ability of immunohistochemistry (IHC), multiparameter flow cytometry (MFC) and fluorescence in situ hybridisation (FISH) to detect clonal plasma cells. We also attempted to outline a te...
A retrospective review was performed on 278 CD138+sorted FISH studies from November 2019 to December 2020 along with their concurrent IHC and MFC results. A p value was computed using McNemar's test f...
Using the Mc Nemar's test for paired data, CD138+sorted FISH studies achieved the highest proportion of positive results and was significantly greater than MFC (63% vs 53%, p=0.01). FISH had more posi...
While CD138+sorted FISH is primarily used for prognostication, it may be employed as a single test for detection and monitoring clonality in certain scenarios. Further studies are needed to monitor th...
Plasma cell vulvitis is a rare inflammatory disorder of the vulva with an unknown aetiology, characterised by mucosal inflammation. It commonly manifests as pain, itching, dyspareunia, and dysuria and...
case report; immunosuppressant; platelet-rich plasma; vulvitis....
The evaluation of plasma cell (PC) compartment is influenced by the quality of bone marrow aspirate (BMA). Herein, we evaluated the impact of sequence of pull on quality of clinical assessment in plas...
Histomorphology along with smears from first pull and second pull BMA and flow cytometric immunophenotyping (FCMI) data from second pull aspirate were evaluated for cellularity and PC%....
Of the 484 samples, BMA smears were adequate in 87.4% of first pull (median PC = 7%; IQR = 2-25%) and 51.2% of second pull samples (median PC = 2%; IQR = 0.5-12%; p < 0.001). Recovery of PC was least ...
First pull BMA smears were of superior quality but inadequate in one-tenth of samples. Second pull smears underreported PC% and recovery of PC compartment was poorest on FCMI. Concurrent bone marrow b...
Next-generation sequencing (NGS) detects somatic mutations in a high proportion of plasma cell dyscrasias (PCD), but is currently not integrated into diagnostic routine. We correlated NGS data with de...
Of the 90 patients the diagnoses comprised multiple myeloma (n = 77), MGUS (n = 7), AL-amyloidosis (n = 4) or solitary plasmocytoma (n = 2). The NGS panel included eight genes CCND1, DIS3, EGR1, FAM46...
Mutations were detected in 64/90 (71%) of cases. KRAS (29%), NRAS (16%) and DIS3 (16%) were most frequently mutated. At least one mutation/sample corresponded to a higher degree of BM involvement with...
The probability of detecting a mutation by NGS in the BM was highest in samples with > 10% clonal PC by MFC, or > 20% PC by BMC/ BMH. We propose further evaluation of these thresholds as a practical c...
Plasma cells (PCs) are essential for the quality and longevity of protective immunity. The canonical humoral response to vaccination involves induction of germinal centers in lymph nodes followed by m...
Plasma cell gingivitis (PCG) is an inflammatory condition that affects the gingival mucosa of the oral cavity. It is characterized by polyclonal dense plasma cell infiltrate in the connective tissue. ...
Primary plasma cell leukemia (PCL) is the most aggressive monoclonal gammopathy. It was formerly characterized by ≥ 20% circulating plasma cells (CTCs) until 2021, when this threshold was decreased to...
We assessed the levels of CTCs by multiparameter flow cytometry in 395 patients with newly diagnosed transplant-ineligible MM to establish a cutoff for CTCs that identifies the patients with ultra-hig...
Newly diagnosed transplant-ineligible patients with MM with 2%-20% CTCs had significantly shorter progression-free survival (3.1...
Our study uncovers that ≥ 2% CTCs is a biomarker of hidden primary PCL and supports the assessment of CTCs by flow cytometry during the diagnostic workup of MM....
Autoantibody (autoAbs) production in osteoarthritis (OA), coupled with evidence of disturbed B-cell homoeostasis, suggest a potential role for B-cells in OA. B-cells can differentiate with T-cell help...
B-cells were isolated from OA and HC. Standardised in vitro models of B-cell differentiation were used comparing T-dep (CD40 (cluster of differentiation-40/BCR (B-cell receptor)-ligation) versus TLR-d...
Compared to HC, circulating OA B-cells showed an overall more mature phenotype. The gene expression profile of synovial OA B-cells resembled that of PCs. Circulating B-cells differentiated under both ...
Our findings suggest that OA B-cells present an altered capacity for proliferation and differentiation while remaining able to produce antibodies, notably in synovium. These findings may partly contri...
A recent study shows that the SNARE protein Sec22b plays a key role in antibody-secreting plasma cell accrual. Without Sec22b, antibody titres were diminished, and plasma cells rare to undetectable. T...
In recent decades, our understanding of periodontitis has evolved from that based on a gross/histologic level to one on a cellular/molecular level. Previous landscape studies have explored molecular s...