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Actions chimiques et utilisations
Actions pharmacologiques
Utilisations thérapeutiques
Agents de l'appareil respiratoire
Antiasthmatiques
Antiasthmatiques : Questions médicales fréquentes
Termes MeSH sélectionnés :
Protein Processing, Post-Translational
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"description": "Comment diagnostiquer l'asthme ?\nQuels tests sont utilisés pour l'asthme ?\nQuels symptômes indiquent l'asthme ?\nL'asthme peut-il être confondu avec d'autres maladies ?\nQuel rôle joue l'historique familial dans le diagnostic ?",
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"@type": "Question",
"name": "Comment diagnostiquer l'asthme ?",
"position": 1,
"acceptedAnswer": {
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"text": "Le diagnostic repose sur l'historique médical, les symptômes et des tests de fonction pulmonaire."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour l'asthme ?",
"position": 2,
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{
"@type": "Question",
"name": "Quels symptômes indiquent l'asthme ?",
"position": 3,
"acceptedAnswer": {
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"text": "Les symptômes incluent la toux, la respiration sifflante, l'essoufflement et la douleur thoracique."
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"@type": "Question",
"name": "L'asthme peut-il être confondu avec d'autres maladies ?",
"position": 4,
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"@type": "Question",
"name": "Quel rôle joue l'historique familial dans le diagnostic ?",
"position": 5,
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}
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{
"@type": "Question",
"name": "Quels sont les symptômes courants de l'asthme ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent toux, respiration sifflante, essoufflement et oppression thoracique."
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"name": "Les symptômes de l'asthme varient-ils selon les saisons ?",
"position": 7,
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"text": "Oui, les symptômes peuvent s'aggraver en raison des allergènes saisonniers comme le pollen."
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"name": "Comment l'exercice affecte-t-il les symptômes ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exercice peut déclencher des symptômes chez certains patients, connu sous le nom d'asthme induit par l'exercice."
}
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{
"@type": "Question",
"name": "Les symptômes nocturnes sont-ils fréquents ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, de nombreux patients éprouvent des symptômes plus graves la nuit ou tôt le matin."
}
},
{
"@type": "Question",
"name": "Comment identifier une crise d'asthme ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une crise se manifeste par une aggravation soudaine des symptômes, nécessitant une intervention rapide."
}
},
{
"@type": "Question",
"name": "Comment prévenir les crises d'asthme ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les déclencheurs, prendre les médicaments prescrits et suivre un plan d'action personnalisé."
}
},
{
"@type": "Question",
"name": "L'éducation des patients est-elle importante ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, comprendre la maladie et son traitement aide à mieux gérer l'asthme au quotidien."
}
},
{
"@type": "Question",
"name": "Quels sont les déclencheurs courants à éviter ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les allergènes, la pollution, la fumée de cigarette et les infections respiratoires sont des déclencheurs."
}
},
{
"@type": "Question",
"name": "Le vaccin contre la grippe est-il recommandé ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il est conseillé pour les patients asthmatiques afin de prévenir les infections respiratoires."
}
},
{
"@type": "Question",
"name": "Comment gérer l'asthme au travail ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Informez votre employeur, évitez les allergènes et ayez toujours votre inhalateur à portée de main."
}
},
{
"@type": "Question",
"name": "Quels types d'antiasthmatiques existent ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antiasthmatiques incluent les bronchodilatateurs et les corticostéroïdes inhalés."
}
},
{
"@type": "Question",
"name": "Comment fonctionnent les bronchodilatateurs ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils dilatent les voies respiratoires, facilitant la respiration en relaxant les muscles bronchiques."
}
},
{
"@type": "Question",
"name": "Quand utiliser un corticostéroïde inhalé ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils sont utilisés quotidiennement pour contrôler l'inflammation et prévenir les symptômes."
}
},
{
"@type": "Question",
"name": "Les antiasthmatiques ont-ils des effets secondaires ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des effets secondaires peuvent inclure des maux de tête, une irritation de la gorge ou des tremblements."
}
},
{
"@type": "Question",
"name": "Comment utiliser un inhalateur correctement ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est essentiel de suivre les instructions, de bien inhaler et de rincer la bouche après usage."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles de l'asthme ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des infections pulmonaires, des crises d'asthme sévères et des hospitalisations."
}
},
{
"@type": "Question",
"name": "L'asthme peut-il affecter la qualité de vie ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'asthme non contrôlé peut limiter les activités quotidiennes et affecter le bien-être général."
}
},
{
"@type": "Question",
"name": "Comment l'asthme peut-il affecter le sommeil ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes nocturnes peuvent perturber le sommeil, entraînant fatigue et problèmes de concentration."
}
},
{
"@type": "Question",
"name": "Les enfants asthmatiques ont-ils des risques accrus ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent avoir des difficultés scolaires et des problèmes sociaux en raison de leur condition."
}
},
{
"@type": "Question",
"name": "L'asthme peut-il entraîner des problèmes cardiaques ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un asthme sévère et mal contrôlé peut augmenter le risque de maladies cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque de l'asthme ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux, des allergies, la pollution et le tabagisme."
}
},
{
"@type": "Question",
"name": "Le stress influence-t-il l'asthme ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut aggraver les symptômes et déclencher des crises d'asthme."
}
},
{
"@type": "Question",
"name": "Les infections respiratoires sont-elles un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les infections virales peuvent déclencher ou aggraver les symptômes de l'asthme."
}
},
{
"@type": "Question",
"name": "Les changements climatiques affectent-ils l'asthme ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les variations de température et l'humidité peuvent exacerber les symptômes asthmatiques."
}
},
{
"@type": "Question",
"name": "Les animaux domestiques peuvent-ils déclencher l'asthme ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les allergènes d'animaux peuvent être des déclencheurs pour certaines personnes asthmatiques."
}
}
]
}
]
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Cardiac resynchronization therapy (CRT) significantly reduces secondary mitral regurgitation (MR) in patients with severe left ventricular systolic dysfunction. However, uncertainty remains as to whet...
Agalsidase beta, an enzyme replacement therapy for Fabry disease, is dosed biweekly at 1 mg/kg body weight, with increasing infusion rates based on tolerability. The US label specifies ≥ 90-min infusi...
Data were available for 436 reduced-duration infusions (< 90 min) and 2242 standard infusions (≥ 90 min). SAEs were rare (0.6%), and the frequency of all safety events decreased over the treatment cou...
The results of this post-hoc analysis demonstrated no significant impact of infusion duration on safety outcomes, and no significant difference in outcomes between patients of different weights. These...
Post-endoscopy esophageal adenocarcinoma (PEEC) and post-endoscopy esophageal neoplasia (PEEN) undermine early cancer detection in Barrett's esophagus (BE). We aimed to assess the magnitude and conduc...
This population-based cohort study was conducted in Denmark, Finland, and Sweden between 2006 and 2020 and included 20,588 patients with newly diagnosed BE. PEEC and PEEN were defined as esophageal ad...
Among 293 patients diagnosed with EAC, 69 (23.5%) were categorized as PEEC, 43 (14.7%) as index EAC, and 181 (61.8%) as incident EAC. The IRs/100,000 person-years for PEEC and incident EAC were 392 (9...
Almost a quarter of all EACs are detected within a year after an ostensibly negative upper endoscopy in patients with newly diagnosed BE. Interventions to improve detection may reduce PEEC/PEEN rates....
Post-stroke depression (PSD) is an important and frequent non-motor complication after a stroke. As valid prediction of PSD occurrence is still not possible, the unselective use of preventive therapy ...
In the prognostic markers of post-stroke depression (PROMoSD) study, a prospective, observational, single-center, investigator-initiated study, we aim to include 100 patients with acute ischemic strok...
The results of PROMoSD will answer the question of whether screening of BRH after AIS improves the prediction of PSD occurrence. A positive result of this study could have direct consequences on psych...
Infection of cells with encephalomyocarditis virus type 1 (EMCV-1,...
To study the role of L and 2A «security» proteins in the suppression of translation of cellular proteins and the efficiency of translation and processing of viral proteins in infected cells....
Mutant variants of EMCV-1 were obtained to study the properties of L and 2A viral proteins:...
The functional inactivation of the 2A protein does not affect the inhibition of cellular protein synthesis. A direct correlation was found between the presence of active L protein and specific inactiv...
A study of the role of EMCV-1 L and 2A proteins during the translational processes of an infected cell, first performed using infectious viral pathogens lacking active L and 2A proteins in one experim...
To investigate the effects of conformational changes and thermal degradation of myofibrillar protein (MP), sarcoplasmic protein (SP), and collagen (CO) on the binding ability for aroma compounds durin...
The design of new protein variants is usually confined to slightly "fixing" an already existing protein, adapting it to certain conditions or to a new substrate. This is relatively easy to do if the f...
Plant-based protein supplements often contain lower amounts of leucine and other essential amino acids (EAAs), potentially making them less effective in stimulating muscle protein synthesis (MPS) than...
The aim of this study was to determine the effect of a novel plant-based blend protein (PBP), PBP with added leucine (PBP + Leu) to levels equivalent to whey protein isolate (WHEY) on aminoacidemia an...
We employed a randomized, double-blind, crossover study consisting of 3 separate study visits to compare PBP, PBP + Leu, and WHEY. To measure MPS response to ingestion of the supplements, a primed con...
All protein supplements increased mixed MPS above postabsorptive levels (...
Consumption of PBP isolate with added leucine stimulated MPS to a similar extent as whey protein in young men and women. PBPs containing higher leucine content promote anabolism to a similar extent as...
Predicting protein-protein interactions (PPIs) from sequence data is a key challenge in computational biology. While various computational methods have been proposed, the utilization of sequence embed...
Addressing this gap, we propose xCAPT5, a novel hybrid classifier that uniquely leverages the T5-XL-UniRef50 protein large language model for generating rich amino acid embeddings from protein sequenc...
This study represents one of the initial efforts to extract informative amino acid embeddings from a large protein language model using a deep and wide convolutional network. Experimental results show...