Comment diagnostiquer la présence d'ANCA ?

Un test sanguin spécifique détecte les ANCA dans le sérum du patient.

Quels tests sont utilisés pour les ANCA ?

Les tests ELISA et indirect immunofluorescence sont couramment utilisés.

Les ANCA sont-ils toujours présents dans les maladies ?

Non, leur présence varie selon la maladie et le stade de l'inflammation.

Quel rôle joue l'historique médical dans le diagnostic ?

L'historique aide à identifier les symptômes et les antécédents de maladies auto-immunes.

Les ANCA peuvent-ils être détectés chez des personnes saines ?

Oui, des ANCA peuvent être présents à faible niveau chez des individus sains.

Quels sont les symptômes associés aux ANCA ?

Les symptômes incluent fatigue, fièvre, perte de poids et douleurs articulaires.

Les ANCA provoquent-ils des symptômes respiratoires ?

Oui, ils peuvent causer des symptômes respiratoires comme la toux et l'essoufflement.

Y a-t-il des symptômes cutanés liés aux ANCA ?

Des éruptions cutanées et des lésions peuvent apparaître chez certains patients.

Les ANCA affectent-ils les reins ?

Oui, ils peuvent entraîner des atteintes rénales, comme la glomérulonéphrite.

Les symptômes des ANCA sont-ils similaires à d'autres maladies ?

Oui, ils peuvent être confondus avec d'autres maladies auto-immunes ou inflammatoires.

Peut-on prévenir les maladies liées aux ANCA ?

Il n'existe pas de méthode de prévention spécifique, mais un mode de vie sain aide.

Les vaccinations sont-elles recommandées pour les patients ANCA ?

Oui, les vaccinations peuvent être recommandées pour prévenir les infections.

Comment réduire le risque de complications ?

Un suivi médical régulier et une gestion proactive des symptômes sont essentiels.

L'évitement de certains médicaments est-il conseillé ?

Oui, certains médicaments peuvent aggraver les symptômes et doivent être évités.

Le stress influence-t-il les maladies ANCA ?

Oui, le stress peut aggraver les symptômes et doit être géré efficacement.

Quels traitements sont utilisés pour les ANCA ?

Les corticostéroïdes et les immunosuppresseurs sont souvent prescrits.

Les traitements sont-ils personnalisés pour chaque patient ?

Oui, le traitement est adapté en fonction de la gravité et des symptômes du patient.

Les ANCA nécessitent-ils un suivi régulier ?

Oui, un suivi régulier est essentiel pour ajuster le traitement et surveiller l'évolution.

Y a-t-il des effets secondaires aux traitements ?

Oui, les traitements peuvent avoir des effets secondaires comme l'infection ou l'ostéoporose.

Les traitements peuvent-ils guérir les ANCA ?

Il n'existe pas de cure, mais les traitements peuvent contrôler les symptômes et la progression.

Quelles sont les complications possibles des ANCA ?

Les complications incluent des atteintes rénales, pulmonaires et cardiovasculaires.

Les ANCA peuvent-ils entraîner des infections ?

Oui, les traitements immunosuppresseurs augmentent le risque d'infections.

Y a-t-il un risque de cancer associé aux ANCA ?

Certaines études suggèrent un risque accru de certains cancers chez les patients ANCA.

Les complications sont-elles réversibles ?

Certaines complications peuvent être réversibles avec un traitement approprié.

Comment surveiller les complications des ANCA ?

Des examens réguliers et des tests sanguins aident à surveiller les complications.

Quels sont les facteurs de risque des ANCA ?

Les facteurs incluent des antécédents familiaux, le tabagisme et certaines infections.

Le sexe influence-t-il le risque d'ANCA ?

Oui, les femmes sont plus souvent touchées par les maladies associées aux ANCA.

L'âge joue-t-il un rôle dans le développement des ANCA ?

Oui, les ANCA apparaissent généralement chez les adultes jeunes à moyens d'âge.

Certaines professions augmentent-elles le risque d'ANCA ?

Oui, les professions exposant à des produits chimiques peuvent augmenter le risque.

Les infections antérieures sont-elles un facteur de risque ?

Oui, certaines infections peuvent déclencher la production d'ANCA chez des individus prédisposés.

Anticorps anti-cytoplasme des polynucléaires neutrophiles

Clinical and Urodynamic Determinants of Earlier Time to Failure for the Artificial Urinary Sphincter.

Jun 2023

DOI: 10.1016/j.urology.2023.03.001 PMID: 36921845

To determine clinical, surgical and urodynamic attributes associated with earlier AUS reintervention. The artificial urinary sphincter (AUS) is the gold standard treatment for postprostatectomy stress... We identified men with post-prostatectomy incontinence who underwent AUS reintervention from 2011 to 2021 at a single center. Urodynamic study, pad weights and voiding diaries are routinely assessed p... A total of 524 records were reviewed and 92 met inclusion. Median time to AUS reintervention was 5.7 years (2.3, 9.4). Indications were mechanical failure (38; 41.3%), sub-cuff atrophy (37; 40.2%), er... Detrusor overactivity is associated with significantly shorter time to AUS failure. This information may allow for more individualized counseling....

Male Humans Urinary Sphincter, Artificial Urodynamics Retrospective Studies +3 autres

Impact of pelvic floor distress on non-invasive urodynamic findings in women.

May 2023

DOI: 10.1016/j.ejogrb.2023.03.017 PMID: 36966588

To compare non-invasive urodynamic findings in women with and without pelvic floor distress and to investigate the patient characteristics affecting maximum flow rates.... This is a retrospective study including data derived from a prospective cohort study evaluating free uroflowmetry findings in asymptomatic and symptomatic women with urinary dysfunction attending the ... The study population (n = 186) comprised asymptomatic (n = 70, 37.6%) and symptomatic (n = 116, 62.4%) women according to the scores of the PFDI-20. Corrected Qmax, TQmax, Tvv and PVR were found signi... Although significantly different, overlapping wide ranges of non-invasive urodynamic findings have been observed in women with and without pelvic floor distress in the present study population. Maximu...

Humans Female Male Pelvic Floor Urodynamics +3 autres

Expert Consensus on Pediatric Urodynamics Reporting Using Modified Delphi Technique.

Jul 2024

DOI: 10.1097/JU.0000000000004000 PMID: 38700226

Urodynamic testing (UDS) is an important tool in the management of pediatric lower urinary tract conditions. There have been notable efforts to standardize pediatric UDS nomenclature and technique, bu... Pediatric urologists regularly performing UDS were queried using a Delphi process. Participants were invited representing varied geographic, experience, and societal involvement. Participants underwen... A diverse sample of 30 providers, representing 27 institutions across 21 US states; Washington, District of Columbia; and Canada completed the study. Participants reported interpreting an average numb... This consensus report details the key elements and structure agreed upon by an expert panel of pediatric urologists. Further standardization of documentation should aid collaboration and research for ...

Delphi Technique Humans Child Urodynamics Consensus +4 autres

Transurethral water vapor ablation of the prostate with the Rezūm system: Urodynamic findings.

01 2023

DOI: 10.1002/nau.25076 PMID: 36335610

The efficacy of the transurethral convective interstitial radiofrequency water vapor thermal ablation of the prostate with the Rezūm system for the treatment of male lower urinary tract symptom due to... This monocentric retrospective pilot study analyzes the data of pressure-flow studies performed before and after 17 Rezūm procedures to answer the question whether thus obtained ablation of prostate t... All the functional outcomes were consistently improved after the procedure, with a median flowrate increase of 5.1 ml/s (p = 0.0022) and a median postvoid residual urine (PVR) reduction of 100 ml (p =... These data show that the possibility to significantly reduce the obstruction grade with even a single Rezūm procedure is concrete and seems to be independent from the degree of the obstruction grade....

Male Humans Prostate Steam Urinary Bladder Neck Obstruction +6 autres

International Survey on Urodynamic Investigations in Women Undergoing Stress Urinary Incontinence Surgery.

Jun 2023

DOI: 10.1016/j.urology.2023.02.024 PMID: 36868410

To evaluate the role of invasive urodynamics (UD) in women candidates for stress urinary incontinence (SUI) surgery.... This was a worldwide survey on current trends in use of preoperative invasive UD in women undergoing SUI surgery. Demographic respondents' data, whether routine invasive UD is performed before surgery... The survey was completed by 504 respondents: urologists 83.1%, gynecologists 16.8%. UD findings were reported influencing the surgical decision in 84.3% of the cases and may change planned surgery in ... This survey showed a worldwide picture on preoperative UD in SUI surgery highlighting the crucial role of UD. UD investigation influences surgical management, but whether it influences outcomes is unc...

Female Humans Urinary Incontinence, Stress Urodynamics Urologic Surgical Procedures +2 autres

Intra-operative Urodynamics: Is the Test an Accurate Representation of the Lower Urinary Tract in Children?

05 2023

DOI: 10.1016/j.urology.2022.12.051 PMID: 36822242

To compare intraoperative UDS results with UDS in the postoperative care unit (PACU) to assess the accuracy and efficacy of intraoperative UDS in children who cannot tolerate ambulatory urodynamic eva... Pediatric patients undergoing intraoperative UDS at a single institution were enrolled over a 5-year time period (1/2013-8/2018). Urodynamics were performed in the operating room under general anesthe... Nineteen patients underwent urodynamic evaluation under general anesthesia and met inclusion criteria. Ten patients (52.6%) underwent 2 filling cycles while awake in PACU, resulting in a total of 48 u... The results of urodynamic testing performed under general anesthesia should be interpreted with caution, as pediatric patients appear to have improved bladder compliance, lower detrusor LPP and decrea...

Humans Child Urinary Bladder Urodynamics Urinary Incontinence +3 autres

Prospective evaluation of a pediatric urodynamics protocol before and after limiting urine cultures.

04 2023

DOI: 10.1016/j.jpurol.2022.12.005 PMID: 36628829

While our institution has historically obtained a urine culture (UCx) from every child at the time of urodynamics (UDS), no consensus exists on UDS UCx utility, and practice varies widely. This study ... A 2-part prospective study of patients undergoing UDS at one pediatric hospital was undertaken, divided into Phase 1 (7/2016-6/2017) with routine UCx at the time of UDS and Phase 2 (7/2019-6/2020) aft... A total of 1,154 UDS were included: 553 in 483 unique patients during Phase 1 and 601 in 533 unique patients during Phase 2. Age, sex, race, ethnicity, and bladder management did not differ significan... In the largest prospective study to date, we found that symptomatic post-UDS UTI was <1% and that UCx at the time of UDS can safely be limited at our hospital. This reduction has important implication... This 2-part prospective evaluation at one pediatric hospital determined that the symptomatic post-UDS UTI rate remained <1% with no identifiable predictors after limiting previously universal UCx at t...

Humans Child Urinary Tract Infections Prospective Studies Urodynamics +2 autres

Influence of urodynamic conditions on bladder sensations and detrusor activity in patients with multiple sclerosis.

11 2022

DOI: 10.1002/nau.25042 PMID: 36098451

The study aimed to assess the impact of bladder filling rate and fluid temperature during urodynamics on bladder sensations and volume of apparition of detrusor overactivity in patients with multiple ... Consecutive PwMS assessed with a standardized urodynamic test including three consecutive cystometries (20 ml/min, 100 ml/min, and 100 ml/min with 4°C fluid (Ice water test [IWT]) between June 2020 an... One hundred and fifty-seven patients (mean age 47.4 ± 11.8 years, median EDSS 3 IQR[2-5], 73.9% of women) were included. Increased filling rate induced delayed bladder sensations (FDV 219 ± 109 ml vs.... Filling rate and fluid temperature impact bladder sensations during cystometry in PwMS. Ice water decreased the volume of the first uninhibited detrusor contraction....

Humans Female Adult Middle Aged Urodynamics +7 autres

Declining utilization of urodynamic studies in urological care in Germany: time to say goodbye?

24 Jul 2024

DOI: 10.1007/s00345-024-05154-3 PMID: 39046605

The number of urodynamic studies (UDS) has been declining steadily in recent decades, yet the reasons behind this trend remain poorly understood. This study aims to investigate the structural aspects ... We surveyed all urological departments performing UDS as well as a representative sample of private practices in Germany in 2023. We examined structural situation, waiting times, capacities and limita... In 2019, 259/474 (55%) urological departments in Germany performed UDS. 206/259 (80%) urological departments responded to the survey. 163/200 (82%) urological departments stated that their capacities ... In German urological departments, UDS capacities are consistently fully utilized, primarily due to staffing shortages. This trend towards centralization prompts questions about the role of UDS in urol...

Humans Germany Urodynamics Urology Procedures and Techniques Utilization

Urodynamic findings in female patients with nocturia: An age-matched case-control study.

01 2023

DOI: 10.1002/nau.25071 PMID: 36259768

Nocturia negatively impacts the quality of life and is associated with poor general health, but our understanding of its etiologies is incomplete. Urodynamic studies (UDS) findings in patients with no... We retrospectively reviewed UDS findings of 1124 patients (2010-2017). A total of 484 (43%) presented with nocturia and 821 (73%) were female. Female patients were separated into age-matched groups wi... A total of 596 female patients were included, 298 (50%) with nocturia and 298 without. Past medical history, including diabetes mellitus and cardiovascular disease, did not differ between groups. Pati... When comparing UDS findings in contemporary, age-matched groups of female patients with and without nocturia, we found only BOO and DV to be associated with nocturia. While the treatment of nocturia i...

Humans Female Male Nocturia Case-Control Studies +5 autres

Anticorps anti-cytoplasme des polynucléaires neutrophiles : Questions médicales fréquentes

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