questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines sécrétoires inhibitrices de protéinases
Inhibiteur tissulaire des métalloprotéinases
Inhibiteur tissulaire de métalloprotéinase-1
Inhibiteur tissulaire de métalloprotéinase-1 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Core Binding Factor Alpha 1 Subunit
Diagnostic
5
TIMP-1
Tests de laboratoire
Inflammation
Cicatrisation
Biomarqueurs
Métalloprotéinases
Cancer
Matrice extracellulaire
Tests immunologiques
Sang
Symptômes
5
Douleurs articulaires
Fibrose
Dégradation
Matrice extracellulaire
Maladies inflammatoires
Arthrite
Inflammation
Métalloprotéinases
Prévention
5
Prévention
Alimentation équilibrée
Activité physique
Gestion du stress
Suivi médical
Déséquilibres
Traitements
5
Thérapies géniques
Inhibiteurs
Cible thérapeutique
Pathologies
Anti-inflammatoires
Médicaments
Essais cliniques
Maladies
Complications
5
Complications
Maladies fibrosantes
Maladies chroniques
Diabète
Santé cardiovasculaire
Athérosclérose
Cancer
Progression tumorale
Effets secondaires
Réactions allergiques
Facteurs de risque
5
Facteurs de risque
Âge avancé
Maladies auto-immunes
Équilibre
Alimentation
Graisses saturées
Inactivité physique
Déséquilibres
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Inhibiteur tissulaire de métalloprotéinase-1 : Questions médicales les plus fréquentes",
"headline": "Inhibiteur tissulaire de métalloprotéinase-1 : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Inhibiteur tissulaire de métalloprotéinase-1 : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-04-08",
"dateModified": "2025-04-03",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Inhibiteur tissulaire de métalloprotéinase-1"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Inhibiteur tissulaire des métalloprotéinases",
"url": "https://questionsmedicales.fr/mesh/D019714",
"about": {
"@type": "MedicalCondition",
"name": "Inhibiteur tissulaire des métalloprotéinases",
"code": {
"@type": "MedicalCode",
"code": "D019714",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D12.776.815.875"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Inhibiteur tissulaire de métalloprotéinase-1",
"alternateName": "Tissue Inhibitor of Metalloproteinase-1",
"code": {
"@type": "MedicalCode",
"code": "D019715",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Anna Pryczynicz",
"url": "https://questionsmedicales.fr/author/Anna%20Pryczynicz",
"affiliation": {
"@type": "Organization",
"name": "Department of Pathomorphology, Medical University of Bialystok, Bialystok, Poland."
}
},
{
"@type": "Person",
"name": "Adina Elena Stanciu",
"url": "https://questionsmedicales.fr/author/Adina%20Elena%20Stanciu",
"affiliation": {
"@type": "Organization",
"name": "Department of Carcinogenesis and Molecular Biology, 'Prof. Dr. Alexandru Trestioreanu' Institute of Oncology, 022328 Bucharest, Romania."
}
},
{
"@type": "Person",
"name": "Adina Zamfir-Chiru-Anton",
"url": "https://questionsmedicales.fr/author/Adina%20Zamfir-Chiru-Anton",
"affiliation": {
"@type": "Organization",
"name": "ENT Department, 'Grigore Alexandrescu' Children's Emergency Hospital, 011743 Bucharest, Romania."
}
},
{
"@type": "Person",
"name": "Marcel Marian Stanciu",
"url": "https://questionsmedicales.fr/author/Marcel%20Marian%20Stanciu",
"affiliation": {
"@type": "Organization",
"name": "Electrical Engineering Faculty, 'Politehnica' University, 060042 Bucharest, Romania."
}
},
{
"@type": "Person",
"name": "Mirela Gherghe",
"url": "https://questionsmedicales.fr/author/Mirela%20Gherghe",
"affiliation": {
"@type": "Organization",
"name": "Department of Nuclear Medicine, 'Prof. Dr. Alexandru Trestioreanu' Institute of Oncology, 022328 Bucharest, Romania."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Core binding factor subunit β plays diverse and essential roles in the male germline.",
"datePublished": "2023-11-02",
"url": "https://questionsmedicales.fr/article/38020932",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3389/fcell.2023.1284184"
}
},
{
"@type": "ScholarlyArticle",
"name": "Anaphase-Promoting Complex Subunit 1 Associates with Bone Mineral Density in Human Osteoporotic Bone.",
"datePublished": "2023-08-17",
"url": "https://questionsmedicales.fr/article/37629076",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/ijms241612895"
}
},
{
"@type": "ScholarlyArticle",
"name": "Increased expression of bone/cartilage-associated genes and core transcription factors in keloids by RNA sequencing.",
"datePublished": "2022-07-03",
"url": "https://questionsmedicales.fr/article/35730251",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1111/exd.14630"
}
},
{
"@type": "ScholarlyArticle",
"name": "Autoantibodies Targeting Proteasome Subunit Alpha Type 1 in Autoimmune Podocytopathies.",
"datePublished": "2024-10-09",
"url": "https://questionsmedicales.fr/article/39382973",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1681/ASN.0000000525"
}
},
{
"@type": "ScholarlyArticle",
"name": "Characterization of open chromatin sensitive to actin polymerization and identification of core-binding factor subunit beta as mechanosensitive nucleocytoplasmic shuttling protein.",
"datePublished": "2024-09-06",
"url": "https://questionsmedicales.fr/article/39239837",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1002/cm.21925"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Acides aminés, peptides et protéines",
"item": "https://questionsmedicales.fr/mesh/D000602"
},
{
"@type": "ListItem",
"position": 3,
"name": "Protéines",
"item": "https://questionsmedicales.fr/mesh/D011506"
},
{
"@type": "ListItem",
"position": 4,
"name": "Protéines sécrétoires inhibitrices de protéinases",
"item": "https://questionsmedicales.fr/mesh/D053491"
},
{
"@type": "ListItem",
"position": 5,
"name": "Inhibiteur tissulaire des métalloprotéinases",
"item": "https://questionsmedicales.fr/mesh/D019714"
},
{
"@type": "ListItem",
"position": 6,
"name": "Inhibiteur tissulaire de métalloprotéinase-1",
"item": "https://questionsmedicales.fr/mesh/D019715"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Inhibiteur tissulaire de métalloprotéinase-1 - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Inhibiteur tissulaire de métalloprotéinase-1",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-11",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Inhibiteur tissulaire de métalloprotéinase-1",
"description": "Comment diagnostiquer une anomalie de TIMP-1 ?\nQuels symptômes indiquent un déséquilibre de TIMP-1 ?\nY a-t-il des biomarqueurs associés à TIMP-1 ?\nQuel rôle joue TIMP-1 dans le cancer ?\nComment TIMP-1 est-il mesuré en clinique ?",
"url": "https://questionsmedicales.fr/mesh/D019715?mesh_terms=Core+Binding+Factor+Alpha+1+Subunit#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Inhibiteur tissulaire de métalloprotéinase-1",
"description": "Quels symptômes sont liés à une surproduction de TIMP-1 ?\nTIMP-1 affecte-t-il la cicatrisation des plaies ?\nQuels signes indiquent une carence en TIMP-1 ?\nY a-t-il des symptômes associés à des maladies inflammatoires ?\nComment TIMP-1 influence-t-il l'inflammation ?",
"url": "https://questionsmedicales.fr/mesh/D019715?mesh_terms=Core+Binding+Factor+Alpha+1+Subunit#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Inhibiteur tissulaire de métalloprotéinase-1",
"description": "Peut-on prévenir les déséquilibres de TIMP-1 ?\nQuels facteurs de mode de vie influencent TIMP-1 ?\nY a-t-il des recommandations pour maintenir TIMP-1 ?\nLes suppléments peuvent-ils aider TIMP-1 ?\nComment le suivi médical aide-t-il TIMP-1 ?",
"url": "https://questionsmedicales.fr/mesh/D019715?mesh_terms=Core+Binding+Factor+Alpha+1+Subunit#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Inhibiteur tissulaire de métalloprotéinase-1",
"description": "Quels traitements ciblent TIMP-1 ?\nTIMP-1 peut-il être utilisé comme cible thérapeutique ?\nQuels médicaments influencent TIMP-1 ?\nY a-t-il des essais cliniques sur TIMP-1 ?\nComment les traitements affectent-ils TIMP-1 ?",
"url": "https://questionsmedicales.fr/mesh/D019715?mesh_terms=Core+Binding+Factor+Alpha+1+Subunit#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Inhibiteur tissulaire de métalloprotéinase-1",
"description": "Quelles complications peuvent survenir avec un excès de TIMP-1 ?\nTIMP-1 est-il lié à des maladies chroniques ?\nComment TIMP-1 affecte-t-il la santé cardiovasculaire ?\nY a-t-il des risques de cancer liés à TIMP-1 ?\nQuels effets secondaires peuvent résulter d'un traitement de TIMP-1 ?",
"url": "https://questionsmedicales.fr/mesh/D019715?mesh_terms=Core+Binding+Factor+Alpha+1+Subunit#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Inhibiteur tissulaire de métalloprotéinase-1",
"description": "Quels facteurs augmentent le risque de déséquilibre de TIMP-1 ?\nLes maladies auto-immunes influencent-elles TIMP-1 ?\nLe stress a-t-il un impact sur TIMP-1 ?\nL'alimentation joue-t-elle un rôle dans TIMP-1 ?\nY a-t-il un lien entre TIMP-1 et l'inactivité physique ?",
"url": "https://questionsmedicales.fr/mesh/D019715?mesh_terms=Core+Binding+Factor+Alpha+1+Subunit#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une anomalie de TIMP-1 ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins mesurant les niveaux de TIMP-1 peuvent être effectués."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent un déséquilibre de TIMP-1 ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme l'inflammation ou des troubles de cicatrisation peuvent survenir."
}
},
{
"@type": "Question",
"name": "Y a-t-il des biomarqueurs associés à TIMP-1 ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des biomarqueurs comme le collagène et les métalloprotéinases sont souvent étudiés."
}
},
{
"@type": "Question",
"name": "Quel rôle joue TIMP-1 dans le cancer ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "TIMP-1 peut inhiber la progression tumorale en régulant la dégradation de la matrice."
}
},
{
"@type": "Question",
"name": "Comment TIMP-1 est-il mesuré en clinique ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est mesuré par des tests immunologiques spécifiques dans des échantillons de sang."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont liés à une surproduction de TIMP-1 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une surproduction peut entraîner des douleurs articulaires et une fibrose tissulaire."
}
},
{
"@type": "Question",
"name": "TIMP-1 affecte-t-il la cicatrisation des plaies ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un excès de TIMP-1 peut ralentir la cicatrisation des plaies."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent une carence en TIMP-1 ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une carence peut se manifester par une dégradation excessive de la matrice extracellulaire."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes associés à des maladies inflammatoires ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des maladies comme l'arthrite peuvent être liées à des niveaux anormaux de TIMP-1."
}
},
{
"@type": "Question",
"name": "Comment TIMP-1 influence-t-il l'inflammation ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "TIMP-1 peut moduler l'inflammation en régulant les métalloprotéinases impliquées."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les déséquilibres de TIMP-1 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à maintenir l'équilibre."
}
},
{
"@type": "Question",
"name": "Quels facteurs de mode de vie influencent TIMP-1 ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme et l'obésité peuvent affecter les niveaux de TIMP-1."
}
},
{
"@type": "Question",
"name": "Y a-t-il des recommandations pour maintenir TIMP-1 ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Pratiquer une activité physique régulière et gérer le stress sont recommandés."
}
},
{
"@type": "Question",
"name": "Les suppléments peuvent-ils aider TIMP-1 ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains suppléments antioxydants peuvent soutenir la régulation de TIMP-1."
}
},
{
"@type": "Question",
"name": "Comment le suivi médical aide-t-il TIMP-1 ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi régulier permet de détecter et de corriger les déséquilibres de TIMP-1."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent TIMP-1 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies géniques et des inhibiteurs spécifiques sont en cours d'étude."
}
},
{
"@type": "Question",
"name": "TIMP-1 peut-il être utilisé comme cible thérapeutique ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, en régulant TIMP-1, on peut potentiellement traiter certaines pathologies."
}
},
{
"@type": "Question",
"name": "Quels médicaments influencent TIMP-1 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains anti-inflammatoires peuvent moduler l'expression de TIMP-1."
}
},
{
"@type": "Question",
"name": "Y a-t-il des essais cliniques sur TIMP-1 ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, plusieurs essais cliniques explorent son rôle dans diverses maladies."
}
},
{
"@type": "Question",
"name": "Comment les traitements affectent-ils TIMP-1 ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements peuvent soit augmenter, soit diminuer les niveaux de TIMP-1 selon le contexte."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec un excès de TIMP-1 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un excès peut entraîner des maladies fibrosantes et des troubles cardiovasculaires."
}
},
{
"@type": "Question",
"name": "TIMP-1 est-il lié à des maladies chroniques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des niveaux anormaux de TIMP-1 sont associés à des maladies chroniques comme le diabète."
}
},
{
"@type": "Question",
"name": "Comment TIMP-1 affecte-t-il la santé cardiovasculaire ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux élevés de TIMP-1 peuvent contribuer à l'athérosclérose."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de cancer liés à TIMP-1 ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux élevés de TIMP-1 peuvent être associés à une progression tumorale."
}
},
{
"@type": "Question",
"name": "Quels effets secondaires peuvent résulter d'un traitement de TIMP-1 ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements peuvent entraîner des effets secondaires comme des réactions allergiques."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de déséquilibre de TIMP-1 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'âge avancé, le tabagisme et l'obésité sont des facteurs de risque connus."
}
},
{
"@type": "Question",
"name": "Les maladies auto-immunes influencent-elles TIMP-1 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les maladies auto-immunes peuvent perturber l'équilibre de TIMP-1."
}
},
{
"@type": "Question",
"name": "Le stress a-t-il un impact sur TIMP-1 ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut affecter les niveaux de TIMP-1 dans l'organisme."
}
},
{
"@type": "Question",
"name": "L'alimentation joue-t-elle un rôle dans TIMP-1 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en graisses saturées peut perturber les niveaux de TIMP-1."
}
},
{
"@type": "Question",
"name": "Y a-t-il un lien entre TIMP-1 et l'inactivité physique ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'inactivité physique peut contribuer à des déséquilibres de TIMP-1."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 03/04/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Department of Pathomorphology, Medical University of Bialystok, Bialystok, Poland.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Department of Carcinogenesis and Molecular Biology, 'Prof. Dr. Alexandru Trestioreanu' Institute of Oncology, 022328 Bucharest, Romania.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
ENT Department, 'Grigore Alexandrescu' Children's Emergency Hospital, 011743 Bucharest, Romania.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Electrical Engineering Faculty, 'Politehnica' University, 060042 Bucharest, Romania.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Department of Nuclear Medicine, 'Prof. Dr. Alexandru Trestioreanu' Institute of Oncology, 022328 Bucharest, Romania.
Department of Radiology, 'Carol Davila' University of Medicine and Pharmacy, 050463 Bucharest, Romania.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
ENT Department, 'Prof. Dr. Dorin Hociota' Institute of Phonoaudiology and Functional ENT and Cervicofacial Surgery, 050751 Bucharest, Romania.
ENT Department, 'Carol Davila' University of Medicine and Pharmacy, 050463 Bucharest, Romania.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Department of Complementary Sciences, 'Carol Davila' University of Medicine and Pharmacy, 050463 Bucharest, Romania.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
ENT Department, 'Carol Davila' University of Medicine and Pharmacy, 050463 Bucharest, Romania.
ENT Department, 'Maria Sklodowska Curie' Children's Emergency Hospital, 077120 Bucharest, Romania.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Chemical and Materials Engineering, University of Nevada, Reno, NV 89557, USA. Electronic address: maryamr@unr.edu.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Division of Clinical Research, First Hospital of Jilin University, Changchun, Jilin Province, China.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Division of Clinical Research, First Hospital of Jilin University, Changchun, Jilin Province, China.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Division of Clinical Research, First Hospital of Jilin University, Changchun, Jilin Province, China.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Division of Clinical Research, First Hospital of Jilin University, Changchun, Jilin Province, China.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Division of Clinical Research, First Hospital of Jilin University, Changchun, Jilin Province, China.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Department of Pediatrics, Gastroenterology, Hepatology, Nutrition and Allergology, Medical University of Bialystok, Bialystok, Poland.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Department of Pathomorphology, Medical University of Bialystok, Bialystok, Poland.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
Department of Pediatrics, Gastroenterology, Hepatology, Nutrition and Allergology, Medical University of Bialystok, Bialystok, Poland.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
From the Department of Epidemiology (C.Z., G.W., Tan Xu, Z.Z., D. Guo, X.Z., A.W., X.B., H.P., Tian Xu, Y.Z.), School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, China; Department of Epidemiology (C.Z., J.C., J.H.), Tulane University School of Public Health and Tropical Medicine, New Orleans, LA; Department of Neurology (Y.P.), Affiliated Hospital of North China University of Science and Technology, Tangshan; Department of Epidemiology (Q.L.), School of Public Health, Taishan Medical College, Taian; Department of Neurology (Z.J.), Kerqin District First People's Hospital of Tongliao City; Department of Neurology (D. Geng), Affiliated Hospital of Xuzhou Medical College, China; Department of Medicine (J.C., J.H.), Tulane University School of Medicine, New Orleans, LA; and Department of Neurology (Tian Xu), Affiliated Hospital of Nantong University, China.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
From the Department of Epidemiology (C.Z., G.W., Tan Xu, Z.Z., D. Guo, X.Z., A.W., X.B., H.P., Tian Xu, Y.Z.), School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, China; Department of Epidemiology (C.Z., J.C., J.H.), Tulane University School of Public Health and Tropical Medicine, New Orleans, LA; Department of Neurology (Y.P.), Affiliated Hospital of North China University of Science and Technology, Tangshan; Department of Epidemiology (Q.L.), School of Public Health, Taishan Medical College, Taian; Department of Neurology (Z.J.), Kerqin District First People's Hospital of Tongliao City; Department of Neurology (D. Geng), Affiliated Hospital of Xuzhou Medical College, China; Department of Medicine (J.C., J.H.), Tulane University School of Medicine, New Orleans, LA; and Department of Neurology (Tian Xu), Affiliated Hospital of Nantong University, China.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
2 publications dans cette catégorie
Affiliations :
From the Department of Epidemiology (C.Z., G.W., Tan Xu, Z.Z., D. Guo, X.Z., A.W., X.B., H.P., Tian Xu, Y.Z.), School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, China; Department of Epidemiology (C.Z., J.C., J.H.), Tulane University School of Public Health and Tropical Medicine, New Orleans, LA; Department of Neurology (Y.P.), Affiliated Hospital of North China University of Science and Technology, Tangshan; Department of Epidemiology (Q.L.), School of Public Health, Taishan Medical College, Taian; Department of Neurology (Z.J.), Kerqin District First People's Hospital of Tongliao City; Department of Neurology (D. Geng), Affiliated Hospital of Xuzhou Medical College, China; Department of Medicine (J.C., J.H.), Tulane University School of Medicine, New Orleans, LA; and Department of Neurology (Tian Xu), Affiliated Hospital of Nantong University, China.
Publications dans "Inhibiteur tissulaire de métalloprotéinase-1" :
Much of the foundation for lifelong spermatogenesis is established prior to puberty, and disruptions during this developmental window negatively impact fertility long into adulthood. However, the fact...
Genome-wide association studies (GWAS) are one of the most common approaches to identify genetic loci that are associated with bone mineral density (BMD). Such novel genetic loci represent new potenti...
Fibroblasts in keloids undergo cell identity transition with altered transcriptional characteristics. However, the core transcription factors driving this cellular reprogramming remain largely unknown...
The antibody against proteasome subunit alpha type 1 (PSMA1) is a podocyte autoantibody in idiopathic nephrotic syndrome (INS) children identified in our previous study. The aim of this study was to e...
The levels of serum anti-PSMA1 autoantibodies in children were detected via protein microarray and compared among different disease groups. The recombinant PSMA1 protein was injected subcutaneously an...
The levels of serum anti-PSMA1 autoantibodies were higher in INS children and varied with urinary protein. In mice immunized with PSMA1, the presence of serum anti-PSMA1 autoantibody caused albuminuri...
PSMA1 played an important role in the maintenance of podocyte morphology and function....
Mechanotransduction leads to a variety of biological responses including gene expression, changes in cell shape, migration, tissue development, and immune responses. Dysregulation of mechanotransducti...
Chagas disease (CD) is considered by the World Health Organisation (WHO) a neglected disease endemic to the Americas, but it has spread throughout the world due to migrations. The disease is almost 10...
Using the total proteins extracted from serum samples of patients confirmed with chronic phase CD; we performed the Bio-SELEX strategy. The best aptamers were selected using next-generation sequencing...
CH1 aptamer was the aptamer selected after the NGS results analysis. The pull-down and mass spectrometry experiments identified the presence of the ATPase alpha subunit of...
We report the ATPase alpha subunit of...
Oral cancer is the major cause of mortality and morbidity worldwide. There are many factors that influence the tumor microenvironment that promotes tumorigenesis. Hypoxia is one of the factors that af...
The aim of the study was to compare the expression of hypoxia-inducible factor 1α (HIF-1α) and hypoxia-inducible factor 2α (HIF-2α) in various histological grades of oral squamous cell carcinoma immun...
Immunohistochemical evaluation of HIF-1α and HIF-2α was done in 90 samples of oral squamous cell carcinoma which were graded histologically into 30 samples each of well, moderately and poorly differen...
All the cases showed positivity for expression of HIF-1α and HIF-2α. The number of positive staining in both markers reduced as the tumor severity increased from well to poorly differentiated. The exp...
Hypoxia is an essential factor that triggers other angiogenic switch and inflammatory factors which facilitates the process of tumorigenesis. This is also important for predicting the treatment outcom...
Aberrant nuclear factor-κB p65 (NF-κB p65) nuclear import commonly occurs in multiple cancers, including colon cancer. According to BioGRID, we noted that Karyopherin subunit alpha 1 (KPNA1), an impor...
KPNA1 expressions at mRNA and protein levels were analyzed in colon cancer tissues. The regulatory effect of KPNA1 on malignant biological properties was detected in SW480 and HCT116 colon cancer cell...
KPNA1 was firstly confirmed as a significantly upregulated gene in our collected clinical colon cancer samples (N = 35). KPNA1 depletion inhibited cell proliferation, induced cell cycle arrest, and di...
The present study uncovers a role of KPNA1-NF-κB p65 axis in promoting colonic carcinogenesis....
Therapy-related acute myeloid leukemia (t-AML) usually stems from exposure of the bone marrow to cytotoxic chemotherapy and/or radiation therapy. t-AML is usually associated with poor overall survival...
Hypoxia-inducible factor 3 subunit alpha (HIF3A) has been implicated in various types of cancers, while its precise role in the lung adenocarcinoma remains unclear. Our study aimed to investigate the ...