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"description": "Comment diagnostiquer une maladie multifactorielle ?\nQuels tests sont utilisés pour le diagnostic ?\nLes antécédents familiaux sont-ils importants ?\nPeut-on identifier des marqueurs génétiques ?\nQuel rôle joue la génétique dans le diagnostic ?",
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"description": "Quelles complications peuvent survenir ?\nLes complications sont-elles évitables ?\nLes complications affectent-elles la qualité de vie ?\nLes complications peuvent-elles être gérées ?\nY a-t-il des complications à long terme ?",
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"@type": "Question",
"name": "Comment diagnostiquer une maladie multifactorielle ?",
"position": 1,
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"text": "Le diagnostic repose sur l'historique familial, les tests génétiques et l'évaluation clinique."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques, des analyses sanguines et des examens cliniques sont couramment utilisés."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux sont-ils importants ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils aident à évaluer le risque et à orienter le diagnostic des maladies multifactorielle."
}
},
{
"@type": "Question",
"name": "Peut-on identifier des marqueurs génétiques ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains marqueurs génétiques peuvent indiquer une prédisposition à des maladies spécifiques."
}
},
{
"@type": "Question",
"name": "Quel rôle joue la génétique dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "La génétique aide à comprendre les facteurs héréditaires contribuant à la maladie."
}
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{
"@type": "Question",
"name": "Quels sont les symptômes courants des maladies multifactorielle ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes varient selon la maladie, mais peuvent inclure fatigue, douleurs et anomalies physiques."
}
},
{
"@type": "Question",
"name": "Les symptômes apparaissent-ils à un âge spécifique ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains symptômes peuvent se manifester à l'enfance, tandis que d'autres apparaissent à l'âge adulte."
}
},
{
"@type": "Question",
"name": "Les symptômes sont-ils similaires à d'autres maladies ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes peuvent se chevaucher avec d'autres conditions, rendant le diagnostic complexe."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des symptômes sans antécédents familiaux ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des facteurs environnementaux peuvent également déclencher des symptômes sans antécédents héréditaires."
}
},
{
"@type": "Question",
"name": "Les symptômes peuvent-ils varier d'une personne à l'autre ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'expression des symptômes peut varier en fonction de la génétique et de l'environnement."
}
},
{
"@type": "Question",
"name": "Comment prévenir les maladies multifactorielle ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention inclut un mode de vie sain, des dépistages réguliers et la gestion des facteurs de risque."
}
},
{
"@type": "Question",
"name": "L'éducation génétique aide-t-elle à la prévention ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'éducation sur les risques génétiques peut aider les individus à prendre des décisions éclairées."
}
},
{
"@type": "Question",
"name": "Les tests génétiques peuvent-ils aider à la prévention ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les tests peuvent identifier les personnes à risque et orienter les mesures préventives."
}
},
{
"@type": "Question",
"name": "Les changements de mode de vie sont-ils efficaces ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, adopter un mode de vie sain peut réduire le risque de développer certaines maladies."
}
},
{
"@type": "Question",
"name": "Les vaccinations jouent-elles un rôle dans la prévention ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines vaccinations peuvent prévenir des infections qui aggravent les maladies multifactorielle."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour les maladies multifactorielle ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des médicaments, des thérapies physiques et des interventions chirurgicales selon la maladie."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils personnalisés ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent être adaptés en fonction des caractéristiques génétiques et des symptômes."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements préventifs ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des interventions préventives peuvent réduire le risque, comme des changements de mode de vie et des dépistages."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils efficaces à long terme ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'efficacité varie selon la maladie et le traitement, nécessitant un suivi régulier."
}
},
{
"@type": "Question",
"name": "Les traitements peuvent-ils avoir des effets secondaires ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, comme tout traitement, il peut y avoir des effets secondaires qui doivent être surveillés."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications varient selon la maladie, mais peuvent inclure des problèmes chroniques et des handicaps."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles évitables ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être évitées par un traitement précoce et une gestion appropriée."
}
},
{
"@type": "Question",
"name": "Les complications affectent-elles la qualité de vie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les complications peuvent significativement impacter la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Les complications peuvent-elles être gérées ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, de nombreuses complications peuvent être gérées avec des traitements appropriés et un suivi."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications à long terme ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies multifactorielle peuvent entraîner des complications à long terme nécessitant un suivi."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'hérédité, l'environnement, le mode de vie et des conditions médicales préexistantes."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation déséquilibrée peut augmenter le risque de certaines maladies multifactorielle."
}
},
{
"@type": "Question",
"name": "Le stress est-il un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut contribuer à l'apparition de maladies multifactorielle."
}
},
{
"@type": "Question",
"name": "L'exercice physique joue-t-il un rôle ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un manque d'exercice peut augmenter le risque de développer certaines maladies."
}
},
{
"@type": "Question",
"name": "Les facteurs environnementaux sont-ils significatifs ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des toxines et à des polluants peut augmenter le risque de maladies multifactorielle."
}
}
]
}
]
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Propofol is commonly used to induce general anesthesia; however, the pain caused during propofol injection is a disadvantage. This study aimed to assess whether deep breathing attenuates propofol inje...
This prospective, single-blind, randomized controlled study included 200 patients who were scheduled to undergo elective surgery under general anesthesia and randomly and equally divided them into gro...
Compared with patients in group C, those in group D showed significantly reduced VAS scores for propofol injection pain (20 [interquartile range (IQR): 0-48] vs. 37 [IQR 9-65], P = 0.017) and recalled...
Deep breathing could be an easy, safe, and inexpensive method for reducing pain during propofol injection....
The symptom-complex irritability, widely used in descriptions of bipolar patients' manic and mixed states, also represents a common feature in depressive phases. Irritability negatively affects the cl...
180 inpatients were randomly assigned to: Group A exposed to bright light therapy (BLT) daily, or Group B treated with pharmacotherapy only. A qualitative assessment of irritability was performed afte...
Group A showed about one-third fewer cases of irritability compared to Group B, this reduction was not related to the overall remission of depressive symptoms....
The present study supports the usefulness of BLT in irritability in bipolar depression....
A four-week-long field intervention experiment was conducted in twenty-nine bedrooms with extract ventilation systems and air inlet vents. During the first week no interventions took place. In the thr...
To evaluate the efficacy and safety of acupuncture in the treatment of endometriosis-associated pain....
A multicenter, randomized, single-blind, placebo-controlled trial....
Four tertiary hospitals in Jiangxi and Hainan Provinces....
Women with endometriosis-associated pain aged between 20 and 40 years....
Subjects were assigned randomly to receive either acupuncture or sham acupuncture treatment for 12 weeks, starting one week before each expected menstruation and administered as a 30-minute session on...
Changes in maximum pain as assessed with the visual analog scale (VAS) for various pelvic pain, duration of dysmenorrhea, and scores on the Multidimensional Pain Inventory, Beck Depression Inventory, ...
A total of 106 women were assigned randomly to the acupuncture and sham groups. In the acupuncture group, the reduction in the dysmenorrhea VAS score was significantly greater after treatment, but not...
Acupuncture is an effective and safe method of relieving dysmenorrhea, shortening the pain duration, and improving wellbeing and quality of life in women with endometriosis-associated pain, although i...
NCT03125304....
Rapid development and implementation of vaccines constituted a crucial step in containing the COVID-19 pandemic. A comprehensive understanding of physiological responses to these vaccines is important...
This study aims to investigate temporal dynamics before and after COVID-19 vaccination in 4 physiological parameters as well as the duration of menstrual cycle phases....
In a prospective trial, 17,825 adults in the Netherlands wore a medical device on their wrist for up to 9 months. The device recorded their physiological signals and synchronized with a complementary ...
The recorded physiological signals demonstrated short-term increases in breathing rate and heart rate after COVID-19 vaccination followed by a prompt rebound to baseline levels likely reflecting biolo...
The observed short-term changes suggest that COVID-19 vaccines are not associated with long-term biophysical issues. Taken together, our work provides valuable insights into continuous fluctuations of...
RR2-10.1186/s13063-021-05241-5....
This study was carried out to determine the effect of progressive muscle relaxation exercises (PMR) on premenstrual syndrome (PMS) symptoms....
The study was designed in a single-blind randomized controlled type. The study was conducted in a hospital in Western Türkiye. Seventy-nine single women who experienced PMS who met the inclusion crite...
At the beginning of the study, it was observed that the individual, health characteristics and PMSS mean scores of the women in the experimental and control groups were similar (p > 0.05). At the end ...
In this study, it was seen that PMR were effective in improving PMS....
To evaluate the efficacy of immersive movement observation in adult patients with haemophilic ankle arthropathy....
Multicentre, single-blind, randomized clinical trial....
48 patients with haemophilia....
Patients were randomly allocated to 2 groups (180º immersive video-based visualization of movement and a control group with no intervention). Twenty-eight consecutive 15-min home sessions, 1 per day, ...
There were intergroup differences in pain intensity (F = 37.14; p < 0.001), conditioned pain modulation (F = 5.40; p = 0.006), and dorsal (F = 19.17; p < 0.001) and plantar (F = 9.27; p<0.001) ankle f...
180º immersive video-based visualization of movement can improve the intensity of pain, conditioned pain modulation, and ankle range of motion in patients with haemophilic ankle arthropathy....
Bowel preparation is a crucial factor affecting the diagnostic accuracy of colonoscopy, and few randomized control trials evaluated enhancement in bowel preparation. In this study, we aimed to evaluat...
The present study is a single-blind randomized controlled trial involving 262 patients scheduled for colonoscopy procedures. These patients were randomly assigned to two groups: an intervention group ...
The number of footsteps recorded in the two groups exhibited a significant difference (P < 0.001). Although there was no statistically significant difference between the intervention and control group...
A higher number of footsteps taken especially more than 6900 can significantly enhance bowel preparation; however, walking exercise as an intervention before colonoscopy is not significantly associate...
ISRCTN32724024 (Registration date:22/08/2018)....
To compare the efficacy of methotrexate and apremilast in psoriatic arthritis (PsA). This Single blinded (physician), parallel group, randomized controlled trial was conducted at a single centre betwe...
Activation of central autonomic pathways, including those regulating the arterial baroreflex, might reduce acute pain. We tested the hypothesis that transcutaneous auricular nerve stimulation (TAN) re...
A total of 86 participants aged >18 yr were randomly assigned to 50 min of either sham or active bilateral TAN, undertaken before, and again 24 h after, surgery for orthopaedic trauma. The primary out...
From June 22, 2021 to July 7, 2022, 79/86 participants (49 yr; 45% female) completed TAN before and after surgery. For the primary outcome, the mean reduction in VAS was 19 mm (95% confidence interval...
Bilateral TAN reduces perioperative pain through autonomic modulation. These proof-of-concept data support a non-pharmacological, generalisable approach to improve perioperative analgesia....