Titre : Techniques de chimie combinatoire

Techniques de chimie combinatoire : Questions médicales fréquentes

Nom anglais: Combinatorial Chemistry Techniques

Descriptor UI: D020650

Tree Number: J01.897.836.249.249

Termes MeSH sélectionnés :

Reproducibility of Results
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Techniques de chimie combinatoire : Questions médicales les plus fréquentes", "headline": "Techniques de chimie combinatoire : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Techniques de chimie combinatoire : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-03-27", "dateModified": "2025-03-22", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Techniques de chimie combinatoire" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Techniques de chimie synthétique", "url": "https://questionsmedicales.fr/mesh/D060326", "about": { "@type": "MedicalCondition", "name": "Techniques de chimie synthétique", "code": { "@type": "MedicalCode", "code": "D060326", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "J01.897.836.249" } } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Technique SELEX", "alternateName": "SELEX Aptamer Technique", "url": "https://questionsmedicales.fr/mesh/D052156", "about": { "@type": "MedicalCondition", "name": "Technique SELEX", "code": { "@type": "MedicalCode", "code": "D052156", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "J01.897.836.249.249.500" } } } ], "about": { "@type": "MedicalCondition", "name": "Techniques de chimie combinatoire", "alternateName": "Combinatorial Chemistry Techniques", "code": { "@type": "MedicalCode", "code": "D020650", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Anna K H Hirsch", "url": "https://questionsmedicales.fr/author/Anna%20K%20H%20Hirsch", "affiliation": { "@type": "Organization", "name": "Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), 66123, Saarbrücken, Germany. anna.hirsch@helmholtz-hips.de." } }, { "@type": "Person", "name": "Lei Hu", "url": "https://questionsmedicales.fr/author/Lei%20Hu", "affiliation": { "@type": "Organization", "name": "School of Pharmacy, Jiangsu University, 301 Xuefu Rd., Zhenjiang, China. Electronic address: leihu@ujs.edu.cn." } }, { "@type": "Person", "name": "Shuang Zhao", "url": "https://questionsmedicales.fr/author/Shuang%20Zhao", "affiliation": { "@type": "Organization", "name": "School of Pharmacy, Jiangsu University, 301 Xuefu Rd., Zhenjiang, China." } }, { "@type": "Person", "name": "Yao Wu", "url": "https://questionsmedicales.fr/author/Yao%20Wu", "affiliation": { "@type": "Organization", "name": "School of Pharmacy, Jiangsu University, 301 Xuefu Rd., Zhenjiang, China." } }, { "@type": "Person", "name": "Mijanur R Molla", "url": "https://questionsmedicales.fr/author/Mijanur%20R%20Molla", "affiliation": { "@type": "Organization", "name": "Institute of Biological and Chemical Systems-Functional Molecular Systems (IBCS-FMS), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "Reproducibility of high-resolution manometry among healthy and constipated persons.", "datePublished": "2022-08-26", "url": "https://questionsmedicales.fr/article/36017816", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1111/nmo.14438" } }, { "@type": "ScholarlyArticle", "name": "Rigor and reproducibility for data analysis and design in the study of eating disorders.", "datePublished": "2022-07-19", "url": "https://questionsmedicales.fr/article/35852964", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1002/eat.23774" } }, { "@type": "ScholarlyArticle", "name": "Multicenter Repeatability and Reproducibility of MR Fingerprinting in Phantoms and in Prostatic Tissue.", "datePublished": "2022-06-17", "url": "https://questionsmedicales.fr/article/35713379", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1002/mrm.29264" } }, { "@type": "ScholarlyArticle", "name": "Improving rigor and reproducibility in western blot experiments with the blotRig analysis.", "datePublished": "2024-09-17", "url": "https://questionsmedicales.fr/article/39284854", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1038/s41598-024-70096-0" } }, { "@type": "ScholarlyArticle", "name": "Validity and Reproducibility of an Electronic Food Frequency Questionnaire in Argentinian Adults.", "datePublished": "2024-05-22", "url": "https://questionsmedicales.fr/article/38892498", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3390/nu16111564" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Technologie, industrie et agriculture", "item": "https://questionsmedicales.fr/mesh/D013676" }, { "@type": "ListItem", "position": 3, "name": "Technologie", "item": "https://questionsmedicales.fr/mesh/D013672" }, { "@type": "ListItem", "position": 4, "name": "Technologie pharmaceutique", "item": "https://questionsmedicales.fr/mesh/D013678" }, { "@type": "ListItem", "position": 5, "name": "Techniques de chimie synthétique", "item": "https://questionsmedicales.fr/mesh/D060326" }, { "@type": "ListItem", "position": 6, "name": "Techniques de chimie combinatoire", "item": "https://questionsmedicales.fr/mesh/D020650" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Techniques de chimie combinatoire - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Techniques de chimie combinatoire", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-16", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Techniques de chimie combinatoire", "description": "Comment la chimie combinatoire aide-t-elle au diagnostic ?\nQuels outils sont utilisés pour le diagnostic en chimie combinatoire ?", "url": "https://questionsmedicales.fr/mesh/D020650?mesh_terms=Reproducibility+of+Results&page=6#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Techniques de chimie combinatoire", "description": "Quels symptômes peuvent être ciblés par des composés issus de la chimie combinatoire ?\nLa chimie combinatoire peut-elle aider à identifier des symptômes ?", "url": "https://questionsmedicales.fr/mesh/D020650?mesh_terms=Reproducibility+of+Results&page=6#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Techniques de chimie combinatoire", "description": "La chimie combinatoire joue-t-elle un rôle dans la prévention des maladies ?\nQuels composés préventifs sont issus de la chimie combinatoire ?", "url": "https://questionsmedicales.fr/mesh/D020650?mesh_terms=Reproducibility+of+Results&page=6#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Techniques de chimie combinatoire", "description": "Quels types de traitements sont développés par la chimie combinatoire ?\nComment la chimie combinatoire améliore-t-elle les traitements ?", "url": "https://questionsmedicales.fr/mesh/D020650?mesh_terms=Reproducibility+of+Results&page=6#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Techniques de chimie combinatoire", "description": "Quelles complications peuvent survenir avec des traitements issus de la chimie combinatoire ?\nComment minimiser les complications des traitements ?", "url": "https://questionsmedicales.fr/mesh/D020650?mesh_terms=Reproducibility+of+Results&page=6#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Techniques de chimie combinatoire", "description": "Quels facteurs de risque sont pris en compte en chimie combinatoire ?\nComment la chimie combinatoire évalue-t-elle les facteurs de risque ?", "url": "https://questionsmedicales.fr/mesh/D020650?mesh_terms=Reproducibility+of+Results&page=6#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment la chimie combinatoire aide-t-elle au diagnostic ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Elle permet de créer des bibliothèques de composés pour identifier des biomarqueurs." } }, { "@type": "Question", "name": "Quels outils sont utilisés pour le diagnostic en chimie combinatoire ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des techniques comme la spectrométrie de masse et la chromatographie sont courantes." } }, { "@type": "Question", "name": "Quels symptômes peuvent être ciblés par des composés issus de la chimie combinatoire ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes variés comme la douleur, l'inflammation ou des troubles neurologiques." } }, { "@type": "Question", "name": "La chimie combinatoire peut-elle aider à identifier des symptômes ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, en développant des molécules qui interagissent avec des cibles biologiques spécifiques." } }, { "@type": "Question", "name": "La chimie combinatoire joue-t-elle un rôle dans la prévention des maladies ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Oui, en développant des agents préventifs et des vaccins ciblés." } }, { "@type": "Question", "name": "Quels composés préventifs sont issus de la chimie combinatoire ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Des inhibiteurs d'enzymes ou des modulateurs de récepteurs pour prévenir des maladies." } }, { "@type": "Question", "name": "Quels types de traitements sont développés par la chimie combinatoire ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Des traitements pour des maladies comme le cancer, le diabète et les infections." } }, { "@type": "Question", "name": "Comment la chimie combinatoire améliore-t-elle les traitements ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Elle permet de découvrir des médicaments plus efficaces et avec moins d'effets secondaires." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec des traitements issus de la chimie combinatoire ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Des complications comme des réactions allergiques ou des résistances médicamenteuses." } }, { "@type": "Question", "name": "Comment minimiser les complications des traitements ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "En optimisant la structure des composés pour réduire les effets indésirables." } }, { "@type": "Question", "name": "Quels facteurs de risque sont pris en compte en chimie combinatoire ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Des facteurs comme la génétique, l'environnement et le mode de vie des patients." } }, { "@type": "Question", "name": "Comment la chimie combinatoire évalue-t-elle les facteurs de risque ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "En développant des modèles prédictifs basés sur des données biologiques et chimiques." } } ] } ] }

Sous-catégories

1 au total
└─

Technique SELEX

SELEX Aptamer Technique D052156 - J01.897.836.249.249.500

Sources (10000 au total)

Reproducibility of high-resolution manometry among healthy and constipated persons.

12 2022
DOI: 10.1111/nmo.14438 PMID: 36017816

Although high-resolution manometry (HR_ARM) is commonly used to diagnose defecatory disorders, its intraindividual day-to-day reproducibility is unknown. Since these measurements entail voluntary effo... In 22 healthy women (35 years [14] mean [SD]) and 53 constipated patients (42 years [13], 46 women), the rectal balloon expulsion time (BET), and anorectal pressures were measured with HR_ARM on 2 day... Among constipated patients, the anal resting (mean CCC [95%CI] 0.62 [0.43-0.76]) and squeeze pressures (CCC 0.65 [0.47-0.79]), rectoanal gradient during evacuation (CCC 0.42 [0.17-0.62]), and rectal s... While HR_ARM variables and the BET are reproducible within healthy and constipated persons, the outcome on repeat testing differed in 79% of constipated patients....

Humans Female Reproducibility of Results Manometry Constipation +3 autres

Rigor and reproducibility for data analysis and design in the study of eating disorders.

10 2022
DOI: 10.1002/eat.23774 PMID: 35852964

Incorporating open science practices has become a priority for submission criteria in the International Journal of Eating Disorders (IJED). In this systematic review, we used the rigor and reproducibi... For this systematic review, six trained coders examined 1145 articles published from January 2011 to May 2021, including the 5 years prior to the 2016 introduction of the Open Science Foundation artic... There was evidence of a significant positive relationship between time and total rigor and reproducibility (Total RR) criteria included in IJED articles following the implementation of preregistration... Although findings indicate that statistical rigor and reproducibility in this field has increased, the lack of direct relationship between open science methods and article visibility for scientists su... Statistical controversies within science threaten the rigor and reproducibility of published research. Open science practices, including the preregistration of study hypotheses, links to statistical c...

Data Analysis Feeding and Eating Disorders Humans Reproducibility of Results Research Personnel

Multicenter Repeatability and Reproducibility of MR Fingerprinting in Phantoms and in Prostatic Tissue.

10 2022
DOI: 10.1002/mrm.29264 PMID: 35713379

To evaluate multicenter repeatability and reproducibility of T... MRF experiments were performed on 5 different 3 Tesla MRI scanners at 3 different institutions: University Hospitals Cleveland Medical Center (Cleveland, OH), Brigham and Women's Hospital (Boston, MA)... The intrascanner variation of values measured using MRF was less than 2% for T... Prostate MRF measurements of T...

Brazil Female Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging +4 autres

Reproducible Speech Research With the Artificial Intelligence-Ready PERCEPT Corpora.

20 06 2023
DOI: 10.1044/2023_JSLHR-22-00343 PMID: 37319018

Publicly available speech corpora facilitate reproducible research by providing open-access data for participants who have consented/assented to data sharing among different research teams. Such corpo... In this research note, we introduce the PERCEPT (Perceptual Error Rating for the Clinical Evaluation of Phonetic Targets) corpora, PERCEPT-R (Rhotics) and PERCEPT-GFTA (Goldman-Fristoe Test of Articul... We demonstrate the use of PERCEPT corpora, PhonBank, and Phon for clinical training and research questions appropriate to child citation speech. Increased use of these tools has the potential to enhan...

Child Adolescent Humans Speech Artificial Intelligence +4 autres

Reproducibility of the 6-minute walk test in lung transplant recipients.

Oct 2023
DOI: 10.1007/s00508-022-02132-w PMID: 36576557

There is reason to believe that the favorable measurement properties of the 6‑minute walk test (6MWT) reported for retest reliability and its capability to detect a true change in healthy individuals ... Immediately before postacute rehabilitation, 50 LuTXr completed 6MWT testing twice, separated by 1-2 workdays (retest reliability), and were reassessed after completion of rehabilitation 2 months late... Baseline retest 6‑minute walk distance (6MWD) and the age-related predicted walking distance (6MWD%... The 6MWT overall represents a reliable functional performance tool in LuTXr that is sensitive to detect changes in physical performance as a result of medical postacute rehabilitation....

Humans Walk Test Reproducibility of Results Exercise Test Quality of Life +3 autres

Improved reproducibility for myocardial ASL: Impact of physiological and acquisition parameters.

01 2024
DOI: 10.1002/mrm.29834 PMID: 37667643

To investigate and mitigate the influence of physiological and acquisition-related parameters on myocardial blood flow (MBF) measurements obtained with myocardial Arterial Spin Labeling (myoASL).... A Flow-sensitive Alternating Inversion Recovery (FAIR) myoASL sequence with bSSFP and spoiled GRE (spGRE) readout is investigated for MBF quantification. Bloch-equation simulations and phantom experim... Simulated and phantom experiments showed a strong dependence on AMS and FA (... Our results show that physiological and acquisition-related factors can lead to spurious changes in myoASL-MBF if not accounted for. Using individual...

Humans Reproducibility of Results Coronary Circulation Myocardium Heart Rate +2 autres