Titre : Syndromes parkinsoniens

Syndromes parkinsoniens : Questions médicales fréquentes

Termes MeSH sélectionnés :

Double-Blind Method
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"name": "Diagnostic", "headline": "Diagnostic sur Syndromes parkinsoniens", "description": "Comment diagnostiquer un syndrome parkinsonien ?\nQuels tests sont utilisés pour le diagnostic ?\nQuels sont les critères de diagnostic ?\nPeut-on confondre avec d'autres maladies ?\nQuel rôle joue l'historique médical ?", "url": "https://questionsmedicales.fr/mesh/D020734?mesh_terms=Double-Blind+Method&page=5#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Syndromes parkinsoniens", "description": "Quels sont les symptômes moteurs principaux ?\nQuels symptômes non moteurs sont fréquents ?\nComment évoluent les symptômes ?\nY a-t-il des symptômes précoces ?\nLes symptômes affectent-ils la qualité de vie ?", "url": "https://questionsmedicales.fr/mesh/D020734?mesh_terms=Double-Blind+Method&page=5#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Syndromes parkinsoniens", "description": "Peut-on prévenir les syndromes parkinsoniens ?\nQuel rôle joue l'exercice physique ?\nL'alimentation influence-t-elle le risque ?\nY a-t-il des facteurs environnementaux à considérer ?\nLe stress a-t-il un impact ?", "url": "https://questionsmedicales.fr/mesh/D020734?mesh_terms=Double-Blind+Method&page=5#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Syndromes parkinsoniens", "description": "Quels sont les traitements médicamenteux ?\nLa chirurgie est-elle une option ?\nQuels sont les effets secondaires des médicaments ?\nY a-t-il des thérapies complémentaires ?\nComment gérer les symptômes non moteurs ?", "url": "https://questionsmedicales.fr/mesh/D020734?mesh_terms=Double-Blind+Method&page=5#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Syndromes parkinsoniens", "description": "Quelles sont les complications courantes ?\nComment les chutes affectent-elles les patients ?\nLes troubles cognitifs sont-ils fréquents ?\nQuelles sont les complications psychologiques ?\nComment gérer les complications ?", "url": "https://questionsmedicales.fr/mesh/D020734?mesh_terms=Double-Blind+Method&page=5#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Syndromes parkinsoniens", "description": "Quels sont les principaux facteurs de risque ?\nLe sexe influence-t-il le risque ?\nLes traumatismes crâniens sont-ils un facteur ?\nL'exposition professionnelle joue-t-elle un rôle ?\nY a-t-il des liens avec d'autres maladies ?", "url": "https://questionsmedicales.fr/mesh/D020734?mesh_terms=Double-Blind+Method&page=5#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer un syndrome parkinsonien ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic repose sur l'examen clinique et l'évaluation des symptômes moteurs et non moteurs." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour le diagnostic ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests d'imagerie comme l'IRM et des évaluations neuropsychologiques peuvent être réalisés." } }, { "@type": "Question", "name": "Quels sont les critères de diagnostic ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Les critères incluent la bradykinésie, la rigidité et les tremblements au repos." } }, { "@type": "Question", "name": "Peut-on confondre avec d'autres maladies ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des maladies comme la maladie de Wilson ou des syndromes atypiques peuvent être confondues." } }, { "@type": "Question", "name": "Quel rôle joue l'historique médical ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "L'historique médical aide à identifier des facteurs de risque et des symptômes précurseurs." } }, { "@type": "Question", "name": "Quels sont les symptômes moteurs principaux ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes moteurs incluent la bradykinésie, la rigidité, et les tremblements." } }, { "@type": "Question", "name": "Quels symptômes non moteurs sont fréquents ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes non moteurs incluent la dépression, l'anxiété et les troubles du sommeil." } }, { "@type": "Question", "name": "Comment évoluent les symptômes ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes évoluent progressivement, souvent en s'aggravant avec le temps." } }, { "@type": "Question", "name": "Y a-t-il des symptômes précoces ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des symptômes comme la perte de l'odorat ou des troubles du sommeil peuvent apparaître tôt." } }, { "@type": "Question", "name": "Les symptômes affectent-ils la qualité de vie ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les symptômes peuvent considérablement réduire la qualité de vie des patients." } }, { "@type": "Question", "name": "Peut-on prévenir les syndromes parkinsoniens ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Il n'existe pas de méthode de prévention garantie, mais un mode de vie sain peut aider." } }, { "@type": "Question", "name": "Quel rôle joue l'exercice physique ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "L'exercice régulier peut améliorer la santé neurologique et retarder l'apparition des symptômes." } }, { "@type": "Question", "name": "L'alimentation influence-t-elle le risque ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation riche en antioxydants peut réduire le risque de développer la maladie." } }, { "@type": "Question", "name": "Y a-t-il des facteurs environnementaux à considérer ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exposition à certains pesticides et toxines peut augmenter le risque de Parkinson." } }, { "@type": "Question", "name": "Le stress a-t-il un impact ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Le stress chronique peut aggraver les symptômes et influencer la progression de la maladie." } }, { "@type": "Question", "name": "Quels sont les traitements médicamenteux ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent la lévodopa, les agonistes de la dopamine et les inhibiteurs de la COMT." } }, { "@type": "Question", "name": "La chirurgie est-elle une option ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la stimulation cérébrale profonde peut être envisagée pour certains patients." } }, { "@type": "Question", "name": "Quels sont les effets secondaires des médicaments ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Les effets secondaires peuvent inclure des nausées, des vertiges et des mouvements involontaires." } }, { "@type": "Question", "name": "Y a-t-il des thérapies complémentaires ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la physiothérapie et l'ergothérapie peuvent aider à améliorer la fonction motrice." } }, { "@type": "Question", "name": "Comment gérer les symptômes non moteurs ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Des traitements psychologiques et des médicaments peuvent aider à gérer les symptômes non moteurs." } }, { "@type": "Question", "name": "Quelles sont les complications courantes ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent les chutes, les troubles de la déglutition et les infections." } }, { "@type": "Question", "name": "Comment les chutes affectent-elles les patients ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Les chutes peuvent entraîner des blessures graves, comme des fractures, et réduire l'autonomie." } }, { "@type": "Question", "name": "Les troubles cognitifs sont-ils fréquents ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Oui, de nombreux patients développent des troubles cognitifs ou démence au cours de la maladie." } }, { "@type": "Question", "name": "Quelles sont les complications psychologiques ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Les patients peuvent souffrir de dépression, d'anxiété et d'isolement social." } }, { "@type": "Question", "name": "Comment gérer les complications ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Une approche multidisciplinaire est essentielle pour gérer les complications efficacement." } }, { "@type": "Question", "name": "Quels sont les principaux facteurs de risque ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent l'âge avancé, les antécédents familiaux et l'exposition à des toxines." } }, { "@type": "Question", "name": "Le sexe influence-t-il le risque ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les hommes sont généralement plus susceptibles de développer des syndromes parkinsoniens." } }, { "@type": "Question", "name": "Les traumatismes crâniens sont-ils un facteur ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des traumatismes crâniens répétés peuvent augmenter le risque de développer la maladie." } }, { "@type": "Question", "name": "L'exposition professionnelle joue-t-elle un rôle ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines professions exposant à des produits chimiques peuvent augmenter le risque." } }, { "@type": "Question", "name": "Y a-t-il des liens avec d'autres maladies ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Certaines maladies auto-immunes et métaboliques peuvent être associées à un risque accru." } } ] } ] }

Sources (10000 au total)

Individualized Homeopathic Medicines in the Treatment of Psoriasis Vulgaris: Double-Blind, Randomized, Placebo-Controlled Trial.

Psoriasis is a chronic inflammatory skin disorder, affecting the trunk and extensor surfaces of the limbs and scalp predominantly. Worldwide prevalence ranges between 0.1 and 11.4%, and in India betwe... This 6-month, double-blind, randomized trial was conducted on 51 patients suffering from psoriasis at the National Institute of Homoeopathy, India. Patients were randomized to receive either individua... Although intragroup changes were significant in both groups in the outcome measures, improvements were significantly higher in the IHMs group than in placebos in PASI scores after 6 months of interven... IHMs exhibited better results than placebos in the treatment of psoriasis. Further research is warranted.... <title>Einleitung</title>Psoriasis ist eine chronisch entzündliche Hauterkrankung, die vor allem den Körperstamm und die Streckseiten der Extremitäten sowie die Kopfhaut betrifft. Die weltweite Präval...

Efficacy of Oral Psyllium in Pediatric Irritable Bowel Syndrome: A Double-Blind Randomized Control Trial.

Pediatric irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder with variable response to various therapeutic agents. Psyllium has been proven to be effective in adults; howe... In this double-blind randomized controlled trial, 43 children were assigned to psyllium arm (Group A) and 38 into placebo arm (Group B). Severity is assessed at baseline and after 4 weeks of treatment... Mean ages (±SD; in years) of Groups A and B were 9.87 (2.7) and 9.82 (3.17), respectively, with median duration of illness of 12 months. At baseline, type, severity, and parameters (IBS-SSS) of IBS we... Psyllium husk is effective for the therapy of pediatric IBS when compared with placebo in short term....

Galcanezumab in episodic migraine: the phase 3, randomized, double-blind, placebo-controlled PERSIST study.

Galcanezumab, a humanized monoclonal antibody that binds calcitonin gene-related peptide, has demonstrated efficacy and good tolerability in patients with episodic migraine in previous phase 3 trials.... This phase 3 study was conducted at 40 centers in China (n = 26), India (n = 10), and Russia (n = 4). Eligible adult patients with episodic migraine were randomized in a 1:1 ratio to receive monthly g... In total, 520 patients were randomized and received at least one dose of galcanezumab (N = 261) or placebo (N = 259). The least squares (LS) mean reduction from baseline in monthly MHDs over 3 months ... Galcanezumab 120 mg once monthly was effective and well tolerated in patients with episodic migraine from China, India, and Russia.... ClinicalTrials.gov Identifier NCT03963232 (PERSIST), registered May 24, 2019....

The minimal important difference in obsessive-compulsive disorder: An analysis of double-blind SSRI trials in adults.

The change in symptoms necessary to be clinically relevant in obsessive-compulsive disorder (OCD) is currently unknown. In this study, we aimed to create an empirically validated threshold for clinica... We analyzed individual participant data from short-term, double-blind, placebo-controlled registration trials of selective serotonin reuptake inhibitors in adult OCD patients. Data were collected from... We included 7 trials with a total of 1216 patients. The CGI-scores and YBOCS were moderately to highly correlated. The MID corresponded to 4.9 YBOCS points (95% CI 4.4-5.4) for the full sample, or a 2... By linking the YBOCS to the CGI-I, this is the first study to propose an MID in OCD trials. Having a clearly defined MID can guide future clinical research and help interpretation of efficacy of exist...

The clinical effect of benesco™ on reflux symptoms: A double-blind randomized placebo-controlled trial.

Gastroesophageal reflux disease (GERD) is one of the most prevalent gastrointestinal diseases in the western world. Lifestyle modifications and proton pump inhibitors (PPIs) form the basis of the mana... We performed a double-blind randomized placebo-controlled trial in participants with reflux symptoms. Participants were assigned randomly (1:1) to receive 6 weeks of benesco™ (three times daily one lo... One hundred participants were randomized. Treatment success was seen in 18 (39%) of 46 participants in the intervention group versus 21 (47%) of 45 in the placebo group (p = 0.468). In the interventio... In our trial benesco™ showed no significant benefit over placebo at group level....

Turpentine Ointment in Bacterial Skin Infections: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial.

Turpentine-containing substances are considered effective in treating cutaneous bacterial infections, but reliable clinical data are scant.... We investigated the efficacy and safety of an ointment containing larch turpentine (from Larix decidua), eucalyptus oil (from Eucalyptus globulus), and turpentine oil (from Pinus pinaster) in outpatie... 116 outpatients with skin abscesses used verum or placebo for 10 days. Sum score of the patient's discomforts, changes in abscess size, rate of therapeutic success, and complete healing served as outc... Fifty-four patients were treated with verum and 56 with placebo. According to the patient's discomfort sum score, patients in the verum group showed a better improvement compared to the placebo group ... The ointment studied is an effective and safe option for the treatment of bacterial skin diseases....

Individualized Homeopathic Medicines in Treatment of Hyperuricemia: Evaluation by Double-Blind, Randomized, Placebo-Controlled Trial.

Hyperuricemia (HU) is a major health issue in India and across the globe. It increases the disease burden and hampers quality of life. This study was aimed at exploring the effects of individualized h... This double-blind, randomized, placebo-controlled trial was conducted on 60 patients suffering from HU in the outpatient department of D. N. De Homoeopathic Medical College and Hospital, Kolkata. Each... The intention-to-treat sample (... IHMs showed significantly better results than placebos in reducing SUA levels and improving quality of life in patients suffering from HU.... CTRI/2019/10/021503; UTN: U1111-1241-1431....

Individualized Homeopathic Medicines in the Treatment of Tinea Corporis: Double-Blind, Randomized, Placebo-Controlled Trial.

Tinea corporis (TC; ringworm or dermatophytosis) is a superficial skin infection caused by... A double-blind, randomized, placebo-controlled, two parallel arms trial was conducted on 62 individuals suffering from TC at the National Institute of Homoeopathy, India. Participants were randomized ... The primary outcome revealed no improvement in either of the groups (... Results were negative on the primary outcome; however, secondary outcomes included some statistically significant results favoring IHMs against placebo after 3 months.... CTRI/2019/11/021999; UTN: U1111-1242-0070....