Titre : Canaux calciques de type L

Canaux calciques de type L : Questions médicales fréquentes

Termes MeSH sélectionnés :

Neoplasm Recurrence, Local
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"Diagnostic sur Canaux calciques de type L", "description": "Comment diagnostiquer une dysfonction des canaux calciques de type L ?\nQuels examens sont recommandés pour évaluer ces canaux ?\nLes tests génétiques sont-ils utiles pour ces canaux ?\nQuels symptômes peuvent indiquer un problème avec ces canaux ?\nComment évaluer la fonction des canaux calciques ?", "url": "https://questionsmedicales.fr/mesh/D020746?mesh_terms=Neoplasm+Recurrence,+Local&page=3#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Canaux calciques de type L", "description": "Quels sont les symptômes d'une hyperactivité des canaux L ?\nComment se manifestent les troubles liés aux canaux calciques ?\nLes symptômes varient-ils selon l'âge ?\nY a-t-il des signes cliniques spécifiques à surveiller ?\nLes symptômes peuvent-ils être confondus avec d'autres maladies ?", "url": "https://questionsmedicales.fr/mesh/D020746?mesh_terms=Neoplasm+Recurrence,+Local&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Canaux calciques de type L", "description": "Comment prévenir les troubles liés aux canaux calciques ?\nL'alimentation joue-t-elle un rôle préventif ?\nLe stress peut-il affecter ces canaux ?\nEst-il important de contrôler la pression artérielle ?\nLes examens réguliers sont-ils nécessaires ?", "url": "https://questionsmedicales.fr/mesh/D020746?mesh_terms=Neoplasm+Recurrence,+Local&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Canaux calciques de type L", "description": "Quels médicaments sont utilisés pour traiter les troubles des canaux L ?\nLa thérapie physique est-elle bénéfique ?\nLes changements de mode de vie sont-ils recommandés ?\nDes interventions chirurgicales sont-elles possibles ?\nComment surveiller l'efficacité du traitement ?", "url": "https://questionsmedicales.fr/mesh/D020746?mesh_terms=Neoplasm+Recurrence,+Local&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Canaux calciques de type L", "description": "Quelles complications peuvent survenir avec des troubles des canaux L ?\nLes complications sont-elles réversibles ?\nComment les complications affectent-elles la qualité de vie ?\nLes complications sont-elles plus fréquentes chez certaines populations ?\nComment gérer les complications à long terme ?", "url": "https://questionsmedicales.fr/mesh/D020746?mesh_terms=Neoplasm+Recurrence,+Local&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Canaux calciques de type L", "description": "Quels sont les principaux facteurs de risque pour les troubles des canaux L ?\nLe tabagisme influence-t-il ces troubles ?\nL'obésité est-elle un facteur de risque ?\nLe manque d'exercice est-il préoccupant ?\nLe stress chronique est-il un facteur de risque ?", "url": "https://questionsmedicales.fr/mesh/D020746?mesh_terms=Neoplasm+Recurrence,+Local&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une dysfonction des canaux calciques de type L ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests électrophysiologiques et des études d'imagerie peuvent être utilisés." } }, { "@type": "Question", "name": "Quels examens sont recommandés pour évaluer ces canaux ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "L'électrocardiogramme et l'échocardiographie sont souvent recommandés." } }, { "@type": "Question", "name": "Les tests génétiques sont-ils utiles pour ces canaux ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent identifier des mutations liées à des troubles spécifiques." } }, { "@type": "Question", "name": "Quels symptômes peuvent indiquer un problème avec ces canaux ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des palpitations, des douleurs thoraciques ou des évanouissements peuvent survenir." } }, { "@type": "Question", "name": "Comment évaluer la fonction des canaux calciques ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Des tests de contraction musculaire et des mesures de calcium intracellulaire sont utilisés." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une hyperactivité des canaux L ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Des arythmies cardiaques, des douleurs thoraciques et des vertiges peuvent se manifester." } }, { "@type": "Question", "name": "Comment se manifestent les troubles liés aux canaux calciques ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Ils peuvent provoquer des spasmes musculaires, des crampes et des troubles de la conduction." } }, { "@type": "Question", "name": "Les symptômes varient-ils selon l'âge ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les symptômes peuvent être plus prononcés chez les personnes âgées." } }, { "@type": "Question", "name": "Y a-t-il des signes cliniques spécifiques à surveiller ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Surveillez les signes d'insuffisance cardiaque et les troubles neurologiques." } }, { "@type": "Question", "name": "Les symptômes peuvent-ils être confondus avec d'autres maladies ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent être similaires à ceux d'autres maladies cardiaques ou neurologiques." } }, { "@type": "Question", "name": "Comment prévenir les troubles liés aux canaux calciques ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Maintenir un mode de vie sain et gérer les facteurs de risque cardiovasculaires." } }, { "@type": "Question", "name": "L'alimentation joue-t-elle un rôle préventif ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une alimentation riche en calcium et en magnésium peut être bénéfique." } }, { "@type": "Question", "name": "Le stress peut-il affecter ces canaux ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le stress chronique peut perturber la fonction des canaux calciques." } }, { "@type": "Question", "name": "Est-il important de contrôler la pression artérielle ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un bon contrôle de la pression artérielle peut prévenir des complications." } }, { "@type": "Question", "name": "Les examens réguliers sont-ils nécessaires ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des examens réguliers peuvent aider à détecter précocement des problèmes." } }, { "@type": "Question", "name": "Quels médicaments sont utilisés pour traiter les troubles des canaux L ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les bloqueurs des canaux calciques sont couramment prescrits pour ces troubles." } }, { "@type": "Question", "name": "La thérapie physique est-elle bénéfique ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle peut aider à améliorer la fonction musculaire et réduire les symptômes." } }, { "@type": "Question", "name": "Les changements de mode de vie sont-ils recommandés ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une alimentation saine et l'exercice régulier peuvent améliorer la santé cardiaque." } }, { "@type": "Question", "name": "Des interventions chirurgicales sont-elles possibles ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Dans certains cas, des procédures comme l'ablation peuvent être envisagées." } }, { "@type": "Question", "name": "Comment surveiller l'efficacité du traitement ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Des suivis réguliers avec des tests cardiaques et des évaluations cliniques sont nécessaires." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec des troubles des canaux L ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des arythmies, des insuffisances cardiaques et des accidents vasculaires cérébraux peuvent survenir." } }, { "@type": "Question", "name": "Les complications sont-elles réversibles ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être réversibles avec un traitement approprié." } }, { "@type": "Question", "name": "Comment les complications affectent-elles la qualité de vie ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Elles peuvent réduire la qualité de vie en limitant l'activité physique et en causant de l'anxiété." } }, { "@type": "Question", "name": "Les complications sont-elles plus fréquentes chez certaines populations ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elles sont plus fréquentes chez les personnes âgées et celles avec des antécédents familiaux." } }, { "@type": "Question", "name": "Comment gérer les complications à long terme ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Un suivi médical régulier et un traitement adapté sont essentiels pour la gestion." } }, { "@type": "Question", "name": "Quels sont les principaux facteurs de risque pour les troubles des canaux L ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "L'hypertension, le diabète et les antécédents familiaux sont des facteurs clés." } }, { "@type": "Question", "name": "Le tabagisme influence-t-il ces troubles ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le tabagisme augmente le risque de complications cardiovasculaires." } }, { "@type": "Question", "name": "L'obésité est-elle un facteur de risque ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'obésité est associée à une augmentation des troubles cardiaques et vasculaires." } }, { "@type": "Question", "name": "Le manque d'exercice est-il préoccupant ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un mode de vie sédentaire augmente le risque de maladies cardiovasculaires." } }, { "@type": "Question", "name": "Le stress chronique est-il un facteur de risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le stress chronique peut contribuer à des troubles cardiaques et à des arythmies." } } ] } ] }

Sources (10000 au total)

Postoperative venous thromboembolism after surgery for locally recurrent rectal cancer.

Local recurrence is common after curative resections of rectal cancer. Surgical resection is considered a primary curative treatment option for patients with locally recurrent rectal cancer (LRRC). LR... From April 2010 to March 2022, a total of 166 patients underwent surgery for LRRC in the pelvic region at our institutions. Clinicopathological background and VTE incidence were compared retrospective... Among the 166 patients included in the study, 55 patients (33.1%) needed sacral resection. Pharmacological prophylaxis for prevention of VTE was performed in 121 patients (73.3%), and the incidence of... This study demonstrates that surgery for LRRC combined with sacral resection could be a significant risk factor for VTE....

Examination of the effectiveness of local therapy for oligo-recurrence of EGFR-mutated NSCLC.

The effectiveness of local therapy has been reported in patients with oligo-recurrence of non-small cell lung cancer (NSCLC), a metachronous recurrence with a limited number of recurrences, which can ... From 2004 to 2014, 811 patients underwent complete resection for NSCLC at Kitasato University Hospital and, of these, 244 patients developed recurrence. Oligo-recurrence was defined as the presence of... We retrospectively examined and compared the effects of EGFR-TKIs with those of radical local therapy in patients with oligo-recurrent EGFR-mutated NSCLC. The five-year post-recurrence survival (PRS) ... Radical local therapy did not affect PRS in patients with oligo-recurrent EGFR-mutated NSCLC. Even in cases of oligo-recurrence, the administration of local therapy in patients with EGFR-mutated NSCLC...

Development of a consensus-based delineation guideline for locally recurrent rectal cancer.

Neoadjuvant chemoradiotherapy (nCRT) is used in locally recurrent rectal cancer (LRRC) to increase chances of a radical surgical resection. Delineation in LRRC is hampered by complex disease presentat... Eight radiation oncologists, from Dutch and Swedish expert centres, participated in two meetings, delineating GTV and CTV in six cases. Regions at-risk for re-recurrence or irradical resection were id... Inter-observer variation in delineation of LRRC appeared large. Multidisciplinary evaluation per case is beneficial in determining target volumes. The following consensus regarding target volumes was ... This study provides a first consensus-based delineation guideline for LRRC. Analyses of re-recurrences is needed to understand disease behaviour and to optimize delineation guidelines accordingly....

The clinical relevance of various methods of classifying ipsilateral breast tumour recurrence as either true local recurrence or new primary.

Describes the relevance of -various classification methods for ipsilateral breast tumour recurrence (IBTR) as either true recurrence (TR) or new primary (NP) on both disease-specific survival (DSS) an... Two hundred and thirty-four of 4359 women undergoing breast-conserving therapy experienced IBTR. We compared the impact of four known classification methods and two newly created classification method... For three of the methods, a better DSS was observed for NP compared to TR with the hazard ratio (HR) ranging from 0.5 to 0.6. The new Twente method classification, comprising all classification criter... IBTR classified as TR or NP has a prognostic value for both DSS and DMFS, but depends on the classification method used. Developing and validating a generally accepted form of classification are imper...

Optimal surveillance of intraductal papillary mucinous neoplasms of the pancreas focusing on remnant pancreas recurrence after surgical resection.

The international consensus guidelines for intraductal papillary mucinous neoplasm of the pancreas (IPMN) presented clinical features as indications for surgery. Whereas surveillance for recurrence, i... This study aimed to assess the clinical features of recurrence at the remnant pancreas (Rem-Panc) and extra-pancreas (Ex-Panc) after surgery for IPMN. Ninety-one patients of IPMN that underwent detail... The IPMNs were finally diagnosed as low-grade dysplasia (LDA, n = 42), high-grade dysplasia (HAD, n = 19), and invasive carcinoma (IPMC, n = 30). Recurrence was observed in 26 patients (29%), of which... The risk factors for Rem-Panc and Ex-Panc recurrence differ. Therefore, optimal surveillance on these features is desirable to ensure that repeat pancreatectomy for Rem-Panc recurrence can be an appro...

Brain magnetic resonance spectroscopy to differentiate recurrent neoplasm from radiation necrosis: A systematic review and meta-analysis.

Postradiation treatment necrosis is one of the most serious late sequelae and appears within 6 months. The magnetic resonance spectroscopy imaging (MRSI) has been used for the detection of brain tumor... The research was performed in accordance with the preferred reporting items for systematic review and meta-analysis guidelines. International electronic databases including 15 English sources were inv... Nine studies were enrolled in the meta-analysis with a total of 354 patients (203 male and 151 female) whose average age ranged from 4 to 74 years. Anbarloui et al., Elias et al., Nemattalla et al., S... MR spectroscopy is effective in distinguishing recurrent brain tumors from necrosis. Our meta-analysis revealed that Cho/NAA, Cho/Cr, and NAA/Cr ratios were significantly better predictor of detected ...

A systematic review of the pathological determinants of outcome following resection by pelvic exenteration of locally advanced and locally recurrent rectal cancer.

Despite multimodal therapy 5-15% of patients who undergo resection for advanced rectal cancer (LARC) will develop local recurrence. Management of locally recurrent rectal cancer (LRRC) presents a sign... A systematic review was carried out searching MEDLINE, EMBASE and COCHRANE Trials database for all studies assessing pathological factors influencing survival following pelvic exenteration for LARC or... Nine cohort studies met inclusion criteria, reporting outcomes for 2864 patients. Meta-analysis was not possible due to significant heterogeneity of reported outcomes. Resection margin status and noda... Pathological resection margin status is widely demonstrated to influence disease free and overall survival following pelvic exenteration for rectal cancer. With increasing R0 rates, other adverse tumo...

Image-guided navigation for locally advanced primary and locally recurrent rectal cancer: evaluation of its early cost-effectiveness.

A first pilot study showed that an image-guided navigation system could improve resection margin rates in locally advanced (LARC) and locally recurrent rectal cancer (LRRC) patients. Incremental surgi... A Markov decision model was constructed to estimate the expected costs and outcomes for navigated and standard surgery. The input parameters were based on pilot data from a prospective (navigation coh... Based on this early evaluation, navigated surgery showed incremental costs of €3141 and €2896 in LARC and LRRC. In LARC, navigated surgery resulted in 2.05 Quality-Adjusted Life Years (QALYs) vs 2.02 ... Adding navigation system use is expected to be cost-effective in LRRC and has the potential to become cost-effective in LARC. To increase the probability of being cost-effective, it is crucial to opti...

The role of surgery in recurrent local cerebral metastases: a multi-institutional retrospective analysis.

Local recurrent brain metastases are defined as lesions that recur in the brain at the same site after a previous local therapy. In patients already submitted to surgery, a second operation may be pot... 37 patients submitted to surgery for a local, histologically confirmed, recurrent brain metastases between 2000 and 2022 were retrospectively analyzed with respect to the following parameters: age, hi... A significant improvement of post-operative KPS status was obtained after second surgery. At multivariate analysis better results in terms of OS were achieved in patients with a pre-operative KPS ≥ 70... Surgical resection of local recurrent brain metastases may improve patients ́ neurologic conditions allowing more time for systemic therapies to act with a low incidence of surgery-related morbidity a...

Salvage radiotherapy for locally recurrent cervical and endometrial carcinoma: clinical outcomes and toxicities.

The management of locally recurrent gynecological carcinoma remains a challenge due to the limited availability of data. This study aims to share our institutional experience in using definitive radio... The study retrospectively reviewed 20 patients in our hospital completing salvage 3D image-based HDR brachytherapy, with or without EBRT, for locally recurrent cervical and endometrial carcinoma after... During a median observation period of 21 months, the study reported a tumor objective response rate of 95%. The 3-year DFS and OS rates were 89.4% and 90.9%, respectively. The EBRT combined with brach... 3D image-guided brachytherapy combined with EBRT shows effective tumor control and acceptable toxicity profile for women with locally recurrent gynecologic cancer. The success in managing vaginal recu...