Séquence riche en AT : Questions médicales fréquentes
Nom anglais: AT Rich Sequence
Descriptor UI:D020856
Tree Number:G05.360.080.040
Termes MeSH sélectionnés :
Delphi Technique
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Séquence riche en AT : Questions médicales les plus fréquentes",
"headline": "Séquence riche en AT : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Séquence riche en AT : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-05-12",
"dateModified": "2025-05-07",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Séquence riche en AT"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Structures génétiques",
"url": "https://questionsmedicales.fr/mesh/D040342",
"about": {
"@type": "MedicalCondition",
"name": "Structures génétiques",
"code": {
"@type": "MedicalCode",
"code": "D040342",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "G05.360"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Séquence riche en AT",
"alternateName": "AT Rich Sequence",
"code": {
"@type": "MedicalCode",
"code": "D020856",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Norio Matsushima",
"url": "https://questionsmedicales.fr/author/Norio%20Matsushima",
"affiliation": {
"@type": "Organization",
"name": "Center for Medical Education, Sapporo Medical University, Sapporo 060-8556, Japan."
}
},
{
"@type": "Person",
"name": "Robert H Kretsinger",
"url": "https://questionsmedicales.fr/author/Robert%20H%20Kretsinger",
"affiliation": {
"@type": "Organization",
"name": "Department of Biology, University of Virginia, Charlottesville, VA 22904, United States."
}
},
{
"@type": "Person",
"name": "Hiroki Miyashita",
"url": "https://questionsmedicales.fr/author/Hiroki%20Miyashita",
"affiliation": {
"@type": "Organization",
"name": "Institute of Tandem Repeats, Noboribetsu 059-0464, Japan."
}
},
{
"@type": "Person",
"name": "Jean-Louis Mergny",
"url": "https://questionsmedicales.fr/author/Jean-Louis%20Mergny",
"affiliation": {
"@type": "Organization",
"name": "Laboratoire d'Optique et Biosciences, Ecole Polytechnique, CNRS, Inserm, Institut Polytechnique de Paris, 91128 Palaiseau, France."
}
},
{
"@type": "Person",
"name": "Yan Yan",
"url": "https://questionsmedicales.fr/author/Yan%20Yan",
"affiliation": {
"@type": "Organization",
"name": "Department of Emergency Medicine, Affiliated Hospital of Nantong University, Nantong, China."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Using the Behaviour Change Wheel and modified Delphi method to identify behavioural change techniques for improving adherence to smoking cessation medications.",
"datePublished": "2023-07-17",
"url": "https://questionsmedicales.fr/article/37455312",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s12889-023-16278-3"
}
},
{
"@type": "ScholarlyArticle",
"name": "Development of a decision support tool to prevent community acquired pressure injuries for use in the spinal cord injury clinic using the delphi technique.",
"datePublished": "2023-10-12",
"url": "https://questionsmedicales.fr/article/37828368",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1038/s41393-023-00937-8"
}
},
{
"@type": "ScholarlyArticle",
"name": "Delphi studies in social and health sciences-Recommendations for an interdisciplinary standardized reporting (DELPHISTAR). Results of a Delphi study.",
"datePublished": "2024-08-26",
"url": "https://questionsmedicales.fr/article/39186713",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1371/journal.pone.0304651"
}
},
{
"@type": "ScholarlyArticle",
"name": "Factors Associated with Non-Adherence to Self-Management Among Patients with Chronic Obstructive Pulmonary Disease: A Survey Using the Delphi Technique and Analytic Hierarchy Process.",
"datePublished": "2024-06-04",
"url": "https://questionsmedicales.fr/article/38854589",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.2147/COPD.S451332"
}
},
{
"@type": "ScholarlyArticle",
"name": "Delphi method applicability in drug foresight.",
"datePublished": "2024-07-27",
"url": "https://questionsmedicales.fr/article/39068443",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s13011-024-00617-7"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Phénomènes génétiques",
"item": "https://questionsmedicales.fr/mesh/D055614"
},
{
"@type": "ListItem",
"position": 3,
"name": "Structures génétiques",
"item": "https://questionsmedicales.fr/mesh/D040342"
},
{
"@type": "ListItem",
"position": 4,
"name": "Séquence riche en AT",
"item": "https://questionsmedicales.fr/mesh/D020856"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Séquence riche en AT - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Séquence riche en AT",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-13",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Séquence riche en AT",
"description": "Comment identifier une séquence riche en AT ?\nQuels tests génétiques sont utilisés ?\nLes séquences riches en AT sont-elles visibles en microscopie ?\nPeut-on détecter des mutations dans ces séquences ?\nQuel rôle jouent les séquences riches en AT dans le diagnostic ?",
"url": "https://questionsmedicales.fr/mesh/D020856?mesh_terms=Delphi+Technique&page=3#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Séquence riche en AT",
"description": "Quels symptômes sont associés aux anomalies des séquences riches en AT ?\nLes séquences riches en AT causent-elles des maladies ?\nY a-t-il des symptômes spécifiques à surveiller ?\nLes séquences riches en AT affectent-elles le système immunitaire ?\nPeut-on prédire des symptômes par l'analyse des séquences ?",
"url": "https://questionsmedicales.fr/mesh/D020856?mesh_terms=Delphi+Technique&page=3#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Séquence riche en AT",
"description": "Peut-on prévenir les anomalies des séquences riches en AT ?\nQuels conseils pour les familles à risque ?\nL'éducation génétique est-elle importante ?\nLes tests prénataux peuvent-ils aider ?\nY a-t-il des recommandations diététiques ?",
"url": "https://questionsmedicales.fr/mesh/D020856?mesh_terms=Delphi+Technique&page=3#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Séquence riche en AT",
"description": "Quels traitements ciblent les séquences riches en AT ?\nLes médicaments peuvent-ils cibler ces séquences ?\nY a-t-il des approches expérimentales en cours ?\nComment les traitements personnalisés sont-ils appliqués ?\nLes traitements peuvent-ils prévenir des complications ?",
"url": "https://questionsmedicales.fr/mesh/D020856?mesh_terms=Delphi+Technique&page=3#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Séquence riche en AT",
"description": "Quelles complications peuvent survenir ?\nLes complications sont-elles héréditaires ?\nComment gérer les complications ?\nLes complications affectent-elles la qualité de vie ?\nY a-t-il des risques de complications à long terme ?",
"url": "https://questionsmedicales.fr/mesh/D020856?mesh_terms=Delphi+Technique&page=3#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Séquence riche en AT",
"description": "Quels sont les facteurs de risque associés ?\nL'âge parental influence-t-il les risques ?\nLes facteurs environnementaux jouent-ils un rôle ?\nY a-t-il des tests pour évaluer les risques ?\nLes habitudes de vie affectent-elles les risques ?",
"url": "https://questionsmedicales.fr/mesh/D020856?mesh_terms=Delphi+Technique&page=3#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment identifier une séquence riche en AT ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'analyse bioinformatique des séquences d'ADN permet d'identifier les régions riches en AT."
}
},
{
"@type": "Question",
"name": "Quels tests génétiques sont utilisés ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de séquençage et des analyses PCR ciblées peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "Les séquences riches en AT sont-elles visibles en microscopie ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, elles ne sont pas visibles directement en microscopie, mais leur effet peut l'être."
}
},
{
"@type": "Question",
"name": "Peut-on détecter des mutations dans ces séquences ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des mutations peuvent être détectées par séquençage ciblé des régions riches en AT."
}
},
{
"@type": "Question",
"name": "Quel rôle jouent les séquences riches en AT dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent influencer l'expression génique et être liées à certaines pathologies."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont associés aux anomalies des séquences riches en AT ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les anomalies peuvent entraîner des troubles génétiques, mais les symptômes varient."
}
},
{
"@type": "Question",
"name": "Les séquences riches en AT causent-elles des maladies ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent être associées à des maladies génétiques, mais ne causent pas directement."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes spécifiques à surveiller ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes dépendent de la maladie associée, comme des anomalies de développement."
}
},
{
"@type": "Question",
"name": "Les séquences riches en AT affectent-elles le système immunitaire ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent influencer l'expression de gènes immunitaires, mais pas directement."
}
},
{
"@type": "Question",
"name": "Peut-on prédire des symptômes par l'analyse des séquences ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'analyse peut aider à prédire des risques, mais pas tous les symptômes."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les anomalies des séquences riches en AT ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un suivi génétique peut aider à identifier les risques."
}
},
{
"@type": "Question",
"name": "Quels conseils pour les familles à risque ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Consulter un conseiller en génétique pour évaluer les risques et options de dépistage."
}
},
{
"@type": "Question",
"name": "L'éducation génétique est-elle importante ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle aide à comprendre les risques et les implications des séquences riches en AT."
}
},
{
"@type": "Question",
"name": "Les tests prénataux peuvent-ils aider ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les tests prénataux peuvent détecter certaines anomalies génétiques liées aux séquences."
}
},
{
"@type": "Question",
"name": "Y a-t-il des recommandations diététiques ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut soutenir la santé génétique, mais n'influence pas directement."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent les séquences riches en AT ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de traitements spécifiques, mais des thérapies géniques peuvent être envisagées."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils cibler ces séquences ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments peuvent influencer l'expression des gènes associés, indirectement."
}
},
{
"@type": "Question",
"name": "Y a-t-il des approches expérimentales en cours ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des recherches sur les thérapies géniques et les modulateurs d'expression sont en cours."
}
},
{
"@type": "Question",
"name": "Comment les traitements personnalisés sont-ils appliqués ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements sont adaptés en fonction des mutations spécifiques dans les séquences."
}
},
{
"@type": "Question",
"name": "Les traitements peuvent-ils prévenir des complications ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un traitement précoce peut réduire le risque de complications associées."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications génétiques, des troubles de développement et des maladies associées."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles héréditaires ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être héréditaires, selon la mutation spécifique."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une approche multidisciplinaire est souvent nécessaire pour gérer les complications."
}
},
{
"@type": "Question",
"name": "Les complications affectent-elles la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent avoir un impact significatif sur la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de complications à long terme ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines anomalies peuvent entraîner des complications à long terme, nécessitant un suivi."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque associés ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux, l'exposition environnementale et certaines mutations génétiques."
}
},
{
"@type": "Question",
"name": "L'âge parental influence-t-il les risques ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'âge avancé des parents peut augmenter le risque de certaines anomalies génétiques."
}
},
{
"@type": "Question",
"name": "Les facteurs environnementaux jouent-ils un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des toxines ou radiations peut influencer les risques génétiques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des tests pour évaluer les risques ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques peuvent évaluer les risques associés aux séquences riches en AT."
}
},
{
"@type": "Question",
"name": "Les habitudes de vie affectent-elles les risques ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des habitudes de vie saines peuvent réduire certains risques génétiques."
}
}
]
}
]
}
Medication adherence is a crucial component of the pharmacological treatment of smoking. Previous interventions targeted to improve adherence to smoking cessation medications (SCMs) were designed usin...
Recommendations for the design of intervention strategies were based on the BCW guide and six studies conducted by the research team. Factors related to healthcare providers and consumers (person maki...
Following a stepped approach, an adherence support wheel was designed to guide implementation strategies and programmes. Thirteen intervention strategies were selected. The selected interventions incl...
The BCW guide and a modified Delphi were applied successfully to design interventions tailored to improve adherence to SCMs. Improving adherence to SCMs requires a comprehensive intervention approach ...
Delphi Technique....
Describe the development of a decision support tool to prevent community-acquired pressure injuries (CAPrIs) in individuals with spinal cord injury (SCI) for use in SCI clinics, called the Community-A...
Veteran Health Administration Hospital, Chicago, Illinois, USA....
Concept mapping of current pressure injury (PrI) guidelines and qualitative research describing risks, actions, and resources needed to prevent CAPrIs associated with SCI were used to develop 40 veter...
Panelists were 60% female, 62% White, 33% veterans with SCI or caregivers, 33% wound care certified with a mean age of 59 years. Two survey rounds were required for consensus for 41 Item and 38 Action...
The CAPP-FIT could become a useful tool for Veterans living with SCI, caregivers, and SCI providers....
While different proposals exist for a guideline on reporting Delphi studies, none of them has yet established itself in the health and social sciences and across the range of Delphi variants. This see...
In an international Delphi procedure, Delphi experts were surveyed online in three rounds to find consensus on a reporting guideline for Delphi studies in the health and social sciences. The responden...
1,072 experts were invited to participate. A total of 91 experts completed the first Delphi round, 69 experts the second round, and 56 experts the third round. Of the 65 items in the first draft of th...
We assume a high level of acceptance and interdisciplinary suitability regarding the reporting guideline presented here and referred to as the "Delphi studies in social and health sciences-recommendat...
The relevant factors and patterns of non-adherence to self-management among patients with chronic obstructive pulmonary disease (COPD) need to be elucidated to improve self-management....
This study was a survey to prioritize the relevance of factors associated with non-adherence to COPD self-management using the Delphi technique and analytic hierarchy process (AHP)....
A total of 15 expert panels were established to determine the priority of relevant factors in a three-round Delphi survey and an AHP. To develop the preliminary conceptual framework for non-adherence ...
In developing the preliminary conceptual framework, 8 factor categories and 53 factors were identified as relevant to non-adherence to COPD self-management. Of the 53 factors, 22 factors with a CVR of...
Through consensus decision-making by experts, 14 factors were identified as relevant factors associated with non-adherence to COPD self-management. A hierarchical and systematic framework incorporatin...
The aim of the current study was to assess the accuracy of expert predictions, which were derived using a Delphi panel foresight study between 2009 and 2011, on a variety of drug-related topics in Fin...
The material used to evaluate the accuracy of the predictions consists of published reports on statistics, survey results, official register data, wastewater analyses and official documents. Whenever ...
Between 2009 and 2011, the majority - but not all - of the experts accurately predicted an increase in drug use. Indeed, more people experimented with or used drugs, and more drug residues were found ...
It seems to have been easier for the experts to foresee the continuation of existing trends, e.g., increasing use of drugs or widening approval of drugs, than to predict possible changes in the popula...
Moral distress is a psychological concept that describes the harm associated with actions or inactions that oppose an individuals' moral beliefs. Moral distress is linked to moral compromise in the wo...
The aim of this study was to develop a list of situational and outcome statements associated with moral compromise and levels of moral distress in midwifery to inform the development of a tool to meas...
This e-Delphi study was the third stage of a sequential exploratory mixed-methods study. Using an online strategy, three iterative rounds of e-Delphi were collected and analysed for consensus on situa...
Twenty participants contributed across the three rounds. Consensus was met in 40 morally compromising situation statements. The highest level of consensus related to excessive workloads and the associ...
This is the first study to use a consensus method to establish different levels of moral compromise, frustration, distress, and injury in midwifery practice. The findings of this study contribute to a...
Nasal irrigation is regularly used in infants to relieve upper airway symptoms. However, because there is no consensus on good practice, nasal irrigation in infants is described and applied heterogene...
The aim of this study was to establish consensus regarding the use of nasal irrigation in infants....
A panel of Belgian physiotherapists and physicians experienced in performing nasal irrigation in infants were surveyed using the Delphi technique. Three survey rounds were used. Participants rated the...
Thirty experts (12 physicians and 18 physiotherapists) completed all 3 questionnaires. Consensus was achieved for 47 of 75 statements (63%) distributed over the following domains: "contraindications,"...
This study provides the first well-constructed consensus on good practice on nasal irrigation in infants. Consensus on several statements across different domains were established but require validati...
Paracetamol and ibuprofen are the most commonly used drugs for pain treatment in children and their combination has shown improved analgesic effect compared to treatment with either drug alone. Curren...
The survey, conducted with Delphi methodology, involved 75 hospital and outpatient pediatricians with clinical experience in the management of pain in children. Pediatricians involved were asked to va...
The results confirm the importance of the fixed-dose paracetamol and ibuprofen combination for the control of mild-to-moderate acute pain in children. Particularly, this association seems to be approp...
Both the NGT consensus and the broader Delphi consensus confirm the usefulness of the paracetamol-ibuprofen fixed-dose combination in pediatric pain. This is attributed to its superior effectiveness c...
Intersphincteric resection (ISR) is an oncologically complex operation for very low-lying rectal cancers. Yet, definition, anatomical description, operative indications and operative approaches to ISR...
A modified Delphi approach with three rounds of questionnaire was adopted. A total of 29 international experts from 11 countries were recruited for this study. Six domains with a total of 37 statement...
Three rounds of questionnaire were performed (response rate 100%, 89.6%, 89.6%). Agreement (≥80%) reached standardization on 36 statements....
This study provides an international expert consensus-based definition and standardization of ISR. This is the first study standardizing terminology and definition of deep pelvis/anal canal anatomy fr...
The current context of the COVID-19 pandemic has demonstrated the need for home exercise strategies for the relief of neck pain, which, in recent times, has increased. However, there is a gap regardin...
This was an observational study conducted in three stages: (1) Developing an online search of databases for articles on neck pain exercises. (2) Validating a panel of 12 physical therapists, using the...
A protocol was developed with the principles of neck and scapular stabilization and upper limb movements, for a period of 4 weeks. Nine physical therapists completed two rounds online, and all items i...
A 4-week home exercise protocol was created based on the best evidence in the literature, was validated by physical therapists and adapted for the population with neck pain. It proved to be an underst...
GOV: (NCT04187001)....
