Executive functions and play.
Executive functions and play have been researched separately over the last few decades. Only recently has the association between the two constructs received more attention. Thus, a Special Issue on t...
Stabilité de l'ARN : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment évaluer la stabilité de l'ARN ?
On utilise des techniques comme le Northern blot et la PCR en temps réel.
#2
Quels marqueurs indiquent une instabilité de l'ARN ?
Des niveaux élevés de dégradation et des variations dans l'expression génique peuvent indiquer une instabilité.
#3
Quels tests sont utilisés pour mesurer l'ARN ?
Les tests incluent l'électrophorèse et les analyses de séquençage.
#4
Peut-on détecter des anomalies d'ARN ?
Oui, des techniques comme le séquençage de nouvelle génération peuvent détecter des anomalies.
#5
Quel rôle joue l'ARNm dans le diagnostic ?
L'ARNm est crucial pour évaluer l'expression des gènes associés à des maladies.
Symptômes 5
#1
Quels symptômes sont liés à l'instabilité de l'ARN ?
Des symptômes variés peuvent apparaître, selon la maladie sous-jacente, comme la fatigue.
#2
L'instabilité de l'ARN peut-elle causer des maladies ?
Oui, elle est liée à des maladies comme certains cancers et des troubles neurodégénératifs.
#3
Quels signes cliniques sont observés ?
Les signes peuvent inclure des anomalies de croissance ou des troubles métaboliques.
#4
Y a-t-il des symptômes spécifiques aux maladies liées à l'ARN ?
Oui, des symptômes spécifiques peuvent inclure des troubles neurologiques ou immunitaires.
#5
Comment l'instabilité de l'ARN affecte-t-elle la santé ?
Elle peut perturber l'expression génique, entraînant des dysfonctionnements cellulaires.
Prévention 5
#1
Comment prévenir l'instabilité de l'ARN ?
Une alimentation équilibrée et un mode de vie sain peuvent aider à maintenir la stabilité de l'ARN.
#2
Y a-t-il des facteurs environnementaux à éviter ?
Oui, l'exposition à des toxines et à des radiations peut affecter la stabilité de l'ARN.
#3
L'exercice physique influence-t-il l'ARN ?
Oui, l'exercice régulier peut améliorer la santé cellulaire et la stabilité de l'ARN.
#4
Des suppléments peuvent-ils aider ?
Certains suppléments, comme les antioxydants, peuvent soutenir la stabilité de l'ARN.
#5
Comment le stress affecte-t-il l'ARN ?
Le stress chronique peut altérer la stabilité de l'ARN et affecter l'expression génique.
Traitements 5
#1
Quels traitements ciblent l'instabilité de l'ARN ?
Des thérapies géniques et des médicaments stabilisateurs d'ARN sont en développement.
#2
Peut-on utiliser des inhibiteurs pour stabiliser l'ARN ?
Oui, certains inhibiteurs peuvent réduire la dégradation de l'ARN dans les cellules.
#3
Quels médicaments sont efficaces contre l'instabilité de l'ARN ?
Des médicaments comme les antisens oligonucleotides sont utilisés pour cibler l'ARN.
#4
Comment la thérapie génique aide-t-elle ?
Elle peut corriger les défauts d'ARN, améliorant ainsi l'expression génique.
#5
Y a-t-il des traitements expérimentaux ?
Oui, des essais cliniques testent de nouvelles approches pour stabiliser l'ARN.
Complications 5
#1
Quelles complications peuvent survenir ?
Des complications incluent des maladies génétiques, des cancers et des troubles métaboliques.
#2
L'instabilité de l'ARN peut-elle entraîner des cancers ?
Oui, l'instabilité de l'ARN est souvent associée à des mécanismes tumoraux.
#3
Quels troubles métaboliques sont liés à l'ARN ?
Des troubles comme le diabète et l'obésité peuvent être influencés par l'instabilité de l'ARN.
#4
Y a-t-il des risques neurologiques ?
Oui, des maladies neurodégénératives peuvent être exacerbées par l'instabilité de l'ARN.
#5
Comment l'instabilité de l'ARN affecte-t-elle le système immunitaire ?
Elle peut altérer la réponse immunitaire, rendant l'organisme plus vulnérable aux infections.
Facteurs de risque 5
#1
Quels facteurs génétiques influencent l'ARN ?
Des mutations dans des gènes régulateurs peuvent affecter la stabilité de l'ARN.
#2
L'âge est-il un facteur de risque ?
Oui, le vieillissement peut affecter la stabilité de l'ARN et l'expression génique.
#3
Les infections virales impactent-elles l'ARN ?
Certaines infections virales peuvent perturber la stabilité de l'ARN dans les cellules hôtes.
#4
Le tabagisme influence-t-il l'ARN ?
Oui, le tabagisme peut induire des modifications qui affectent la stabilité de l'ARN.
#5
Y a-t-il des facteurs nutritionnels à considérer ?
Oui, une carence en nutriments essentiels peut compromettre la stabilité de l'ARN.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 26/04/2025
Contenu vérifié selon les dernières recommandations médicales
Auteurs principaux
Hannah K Wayment-Steele
3 publications dans cette catégorie
Affiliations :
- Department of Chemistry, Stanford University, Stanford, CA 94305, USA.
- Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Do Soon Kim
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
- Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA.
- Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
John J Nicol
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Roger Wellington-Oguri
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Andrew M Watkins
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
- Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Eterna Participants
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Rhiju Das
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
- Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.
- Department of Physics, Stanford University, Stanford, CA 94305, USA.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Nina Fasching
2 publications dans cette catégorie
Affiliations :
- IMBA-Institute of Molecular Biotechnology, Vienna Biocenter (VBC), Vienna, Austria.
Publications dans "Stabilité de l'ARN" :
-
Transcriptome-Wide Profiling of RNA Stability.
Methods in molecular biology (Clifton, N.J.)
-
Determining mRNA Stability by Metabolic RNA Labeling and Chemical Nucleoside Conversion.
Methods in molecular biology (Clifton, N.J.)
Veronika A Herzog
2 publications dans cette catégorie
Affiliations :
- IMBA-Institute of Molecular Biotechnology, Vienna Biocenter (VBC), Vienna, Austria.
Publications dans "Stabilité de l'ARN" :
-
Transcriptome-Wide Profiling of RNA Stability.
Methods in molecular biology (Clifton, N.J.)
-
Determining mRNA Stability by Metabolic RNA Labeling and Chemical Nucleoside Conversion.
Methods in molecular biology (Clifton, N.J.)
Stefan L Ameres
2 publications dans cette catégorie
Affiliations :
- IMBA-Institute of Molecular Biotechnology, Vienna Biocenter (VBC), Vienna, Austria. stefan.ameres@univie.ac.at.
- Max Perutz Labs, University of Vienna, Vienna Biocenter (VBC), Vienna, Austria. stefan.ameres@univie.ac.at.
Publications dans "Stabilité de l'ARN" :
-
Transcriptome-Wide Profiling of RNA Stability.
Methods in molecular biology (Clifton, N.J.)
-
Determining mRNA Stability by Metabolic RNA Labeling and Chemical Nucleoside Conversion.
Methods in molecular biology (Clifton, N.J.)
Besik Kankia
2 publications dans cette catégorie
Affiliations :
- Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
- Center for RNA Biology, The Ohio State University, Columbus, OH 43210, USA.
- Institute of Biophysics, Ilia State University, Tbilisi, 0162, Republic of Georgia.
Publications dans "Stabilité de l'ARN" :
-
A Chimeric DNA/RNA Antiparallel Quadruplex with Improved Stability.
ChemistryOpen
-
Stability Factors of the Parallel Quadruplexes: DNA Versus RNA.
The journal of physical chemistry. B 2019-01-25
Amos J Nissley
2 publications dans cette catégorie
Affiliations :
- Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, USA.
Publications dans "Stabilité de l'ARN" :
-
Interactions between terminal ribosomal RNA helices stabilize the
RNA (New York, N.Y.) 2023-07-07
-
Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome.
Nucleic acids research
Jamie H D Cate
2 publications dans cette catégorie
Affiliations :
- Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, USA j-h-doudna-cate@berkeley.edu.
- Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.
- Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
Publications dans "Stabilité de l'ARN" :
-
Interactions between terminal ribosomal RNA helices stabilize the
RNA (New York, N.Y.) 2023-07-07
-
Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome.
Nucleic acids research
Seyed-Fakhreddin Torabi
2 publications dans cette catégorie
Affiliations :
- Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
- HHMI, Yale University School of Medicine, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
-
Structural analyses of an RNA stability element interacting with poly(A).
Proceedings of the National Academy of Sciences of the United States of America
-
RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science (New York, N.Y.) 2021-01-07
Jimin Wang
2 publications dans cette catégorie
Affiliations :
- Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
-
Structural analyses of an RNA stability element interacting with poly(A).
Proceedings of the National Academy of Sciences of the United States of America
-
RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science (New York, N.Y.) 2021-01-07
Suzanne J DeGregorio
2 publications dans cette catégorie
Affiliations :
- Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
- HHMI, Yale University School of Medicine, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
-
Structural analyses of an RNA stability element interacting with poly(A).
Proceedings of the National Academy of Sciences of the United States of America
-
RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science (New York, N.Y.) 2021-01-07
Anand T Vaidya
2 publications dans cette catégorie
Affiliations :
- Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
- HHMI, Yale University School of Medicine, New Haven, CT 06536.
- Tata Institute of Fundamental Research Centre for Interdisciplinary Sciences, Tata Institute of Fundamental Research, 10 500046 Hyderabad, India.
Publications dans "Stabilité de l'ARN" :
-
Structural analyses of an RNA stability element interacting with poly(A).
Proceedings of the National Academy of Sciences of the United States of America
-
RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science (New York, N.Y.) 2021-01-07
Joan A Steitz
2 publications dans cette catégorie
Affiliations :
- Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536; wahc@stanford.edu LP26@cornell.edu joan.steitz@yale.edu.
- HHMI, Yale University School of Medicine, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
-
Structural analyses of an RNA stability element interacting with poly(A).
Proceedings of the National Academy of Sciences of the United States of America
-
RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science (New York, N.Y.) 2021-01-07
Jorge R Espinosa
2 publications dans cette catégorie
Affiliations :
- Cavendish Laboratory, Maxwell Centre, Department of Physics, University of Cambridge, Cambridge, United Kingdom. Electronic address: jr752@cam.ac.uk.
Publications dans "Stabilité de l'ARN" :
-
'RNA modulation of transport properties and stability in phase-separated condensates.
Biophysical journal 2021-11-09
-
RNA length has a non-trivial effect in the stability of biomolecular condensates formed by RNA-binding proteins.
PLoS computational biology 2022-02-02
Kathrin Leppek
2 publications dans cette catégorie
Affiliations :
- Department of Genetics, Stanford University, Stanford, CA, 94305, USA.
Publications dans "Stabilité de l'ARN" :
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Sources (10000 au total)
Executive functions and functioning in women with fibromyalgia.
Fibromyalgia (FM) is a chronic condition characterized by widespread pain that is associated with sleep, emotional, and cognitive disturbances, including in executive functions (EFs).... To investigate the relationship between EFs and functionality in women with FM.... The study included 17 women with FM, aged between 30 and 59 years, with no history of neurological disease. The EFs were assessed using the Digit Span Subtest (DS), Five Digit Test, Trail Making Test ... The FM patients showed longer response latency on the HT and TMT. They made fewer errors on part B of the HT, and they performed worse on the DS backward and on the Corsi Block-Tapping Task forward an... The results suggest lower efficiency in processes such as inhibitory control and cognitive flexibility, difficulties in working memory and non-executive processes such as processing speed. Even with p...
The effect of metacognitive executive function training on children's executive function, proactive control, and academic skills.
The current study investigated the effects of metacognitive and executive function (EF) training on childhood EF (inhibition, working memory [WM], cognitive flexibility, and proactive/reactive control...
The depth of executive function: Depth information aids executive function under challenging task conditions.
The present studies investigated how three core aspects of executive functioning may be influenced by the presence of depth information. Specifically, participants were assigned to one of three execut...
Exploring Executive Functioning of Adults With Probable Developmental Coordination Disorder Using the Jansari Assessment of Executive Functions.
Many individuals with Developmental Coordination Disorder (DCD) demonstrate executive functioning difficulties on standardized assessments, yet these difficulties have not been investigated using ecol...
Sleep Duration and Executive Function in Adults.
To review the literature examining the relationship between sleep and cognition, specifically examining the sub-domain of executive function. We explore the impact of sleep deprivation and the importa... Sleep duration and executive function display a quadratic relationship. This suggests an optimal amount of sleep is required for daily cognitive processes. Poor sleep efficiency and sleep fragmentatio...
Hierarchical functional system development supports executive function.
In this perspective, we describe how developmental improvements in youth executive function (EF) are supported by hierarchically organized maturational changes in functional brain systems. We first hi...
Neurobiological perspective on the development of executive functions.
Executive functions are a set of top-down cognitive processes necessary for emotional self-regulation and goal-directed behaviour supporting, among others, academic abilities. Premature infants are at...
An ecological view of executive function in young children: Variation in and predictors of executive function skills over one school year.
For many years, researchers studied executive functions (EFs) in the laboratory with a focus on understanding an individual child's development and brain processes in a controlled environment. Buildin...
Evaluation of functional mobility, balance, and executive functions in children with epilepsy.
It is known that motor skills and executive functions are interrelated in healthy children. The study aims to evaluate the functional mobility, balance and executive functions in children who are diag... The study included 21 children who were diagnosed with epilepsy and have no additional comorbidities and 21 healthy children who had similar age and sex to those diagnosed with epilepsy. Their demogra... Our study found a statistically significant difference between the children with epilepsy and their healthy peers in terms of functional mobility and executive functions (p < 0.05). However, there was... Epilepsy can negatively affect several aspects of functional mobility and executive functions in childhood. According to the results of our study, it is important to recognize the motor skills and exe...