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"@type": "Question",
"name": "Quels examens utilisent l'imagerie 3D ?",
"position": 1,
"acceptedAnswer": {
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"text": "La tomodensitométrie (CT) et l'IRM sont couramment utilisés."
}
},
{
"@type": "Question",
"name": "Comment l'imagerie 3D aide-t-elle au diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet une visualisation détaillée des organes et des tissus, facilitant le diagnostic."
}
},
{
"@type": "Question",
"name": "L'imagerie 3D est-elle utilisée en oncologie ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle est essentielle pour localiser et évaluer les tumeurs."
}
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{
"@type": "Question",
"name": "Peut-on détecter des anomalies avec l'imagerie 3D ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle permet de détecter des anomalies structurelles avec précision."
}
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{
"@type": "Question",
"name": "L'imagerie 3D est-elle utile pour les fractures ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle aide à visualiser les fractures complexes et leur impact sur les tissus environnants."
}
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{
"@type": "Question",
"name": "Quels symptômes peuvent nécessiter une imagerie 3D ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des douleurs persistantes, des anomalies visibles ou des symptômes neurologiques."
}
},
{
"@type": "Question",
"name": "L'imagerie 3D peut-elle aider à évaluer des douleurs abdominales ?",
"position": 7,
"acceptedAnswer": {
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"text": "Oui, elle permet d'identifier des problèmes comme des tumeurs ou des malformations."
}
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"@type": "Question",
"name": "Quels symptômes cardiaques peuvent être évalués par imagerie 3D ?",
"position": 8,
"acceptedAnswer": {
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"text": "Des douleurs thoraciques ou des palpitations peuvent nécessiter une évaluation."
}
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"@type": "Question",
"name": "L'imagerie 3D est-elle utile pour les troubles respiratoires ?",
"position": 9,
"acceptedAnswer": {
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"text": "Oui, elle aide à visualiser les poumons et détecter des anomalies comme des nodules."
}
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"name": "Peut-on détecter des anomalies cérébrales avec l'imagerie 3D ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle est efficace pour visualiser des anomalies comme des tumeurs ou des AVC."
}
},
{
"@type": "Question",
"name": "L'imagerie 3D peut-elle aider à la détection précoce des maladies ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle permet de détecter des maladies à un stade précoce, améliorant les chances de traitement."
}
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{
"@type": "Question",
"name": "Comment l'imagerie 3D contribue-t-elle à la prévention des cancers ?",
"position": 12,
"acceptedAnswer": {
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"text": "Elle permet de surveiller les patients à risque et de détecter des anomalies précoces."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser l'imagerie 3D pour le dépistage ?",
"position": 13,
"acceptedAnswer": {
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"text": "Oui, elle est utilisée pour le dépistage de certaines maladies comme le cancer du sein."
}
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{
"@type": "Question",
"name": "L'imagerie 3D aide-t-elle à évaluer les risques cardiovasculaires ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle permet d'évaluer l'état des artères et de détecter des anomalies."
}
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{
"@type": "Question",
"name": "Peut-on prévenir des maladies avec l'imagerie 3D ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Indirectement, en permettant une détection précoce et un suivi régulier."
}
},
{
"@type": "Question",
"name": "L'imagerie 3D est-elle utilisée pour planifier des interventions chirurgicales ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle permet de planifier avec précision les interventions chirurgicales."
}
},
{
"@type": "Question",
"name": "Comment l'imagerie 3D aide-t-elle en radiothérapie ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet de cibler précisément les tumeurs tout en épargnant les tissus sains."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser l'imagerie 3D pour guider des biopsies ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle aide à localiser précisément les zones à biopsier."
}
},
{
"@type": "Question",
"name": "L'imagerie 3D est-elle utile pour le suivi des traitements ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle permet d'évaluer l'efficacité des traitements au fil du temps."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser l'imagerie 3D pour des traitements non invasifs ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle est utilisée pour des techniques comme l'ablation par radiofréquence."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec l'imagerie 3D ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des réactions allergiques aux agents de contraste ou des effets secondaires liés à l'exposition."
}
},
{
"@type": "Question",
"name": "L'imagerie 3D peut-elle causer des effets secondaires ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, notamment des effets liés à l'exposition aux radiations en cas de CT."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques liés à l'utilisation d'agents de contraste ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des réactions allergiques ou des problèmes rénaux peuvent survenir."
}
},
{
"@type": "Question",
"name": "L'imagerie 3D peut-elle entraîner des faux positifs ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies peuvent être détectées qui ne sont pas cliniquement significatives."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles après une biopsie guidée par imagerie 3D ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des saignements ou des infections peuvent survenir après la procédure."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le besoin d'imagerie 3D ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Antécédents familiaux de maladies, symptômes persistants ou exposition à des risques environnementaux."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque pour l'imagerie 3D ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes âgées sont plus susceptibles de nécessiter des examens d'imagerie."
}
},
{
"@type": "Question",
"name": "Le tabagisme influence-t-il le besoin d'imagerie 3D ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il augmente le risque de maladies pulmonaires nécessitant une évaluation."
}
},
{
"@type": "Question",
"name": "Les antécédents médicaux influencent-ils l'imagerie 3D ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents de maladies peuvent justifier des examens d'imagerie réguliers."
}
},
{
"@type": "Question",
"name": "Y a-t-il des facteurs environnementaux affectant l'imagerie 3D ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des substances toxiques peut augmenter le besoin d'examens."
}
}
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Currently, immunotherapy has entered the clinical diagnosis and treatment guidelines for colon cancer, but existing immunotherapy markers cannot predict the effectiveness of immunotherapy well. This s...
Large deletions and duplications within the low-density lipoprotein receptor (LDLR) gene make up approximately 10% of LDLR pathogenic variants found in Czech patients with familial hypercholesterolemi...
The breakpoint sequence was determined by PCR amplification and Sanger sequencing. To confirm the breakpoint position, an NGS analysis was performed. Haplotype analysis of common LDLR variants was per...
The breakpoints of 8 rearrangements within the LDLR gene were analysed, including the four most common LDLR rearrangements in the Czech population (number of probands ranging from 8 to 28), and four l...
The most common rearrangements of the LDLR gene in the Czech population likely arose from one mutational event. Alu elements likely played a role in the generation of the majority of rearrangements in...
The objective of this multicenter retrospective study aimed to evaluate the association of clinical variables and the incidence of ovarian cancer in patients with BRCA 1-2 mutation carriers who underw...
Patients with a pathogenic mutation of BRCA 1-2 genes and with no evidence of disease are considered eligible. The exclusion criterion was the refusal to undergo the surgery. The retrospective study i...
Age, menarche age, BMI, menopause at time of RRSO, breast cancer first and second-degree relatives, ovarian cancer first and second-degree relatives, estroprogestin use, pregnancy normal full-term del...
184 were recruited. One was excluded. To assess cancer risk, the outcome variable was classified into three classes: no event, cancer and other conditions excluding cancer. 14 women presented ovarian ...
Our study did not demonstrate a correlation between clinical features and the occurrence of precancerous or cancerous lesions in BRCA mutation carrier patients....
This study aimed to conduct a systematic review and meta-analysis of randomized controlled trials to evaluate the effects of elexacaftor-tezacaftor-ivacaftor (ELX-TEZ-IVA) on patients with cystic fibr...
A systematic search was performed in PubMed, Embase, and the Cochrane Library from inception to August 1, 2022. Meta-analysis was conducted using Review Manager 5.3 software....
Six studies comprising seven reports involving a total of 1125 CF patients were included. The meta-analyses indicated that ELX-TEZ-IVA significantly improved the percentage predicted forced expiratory...
ELX-TEZ-IVA demonstrated efficacy in improving ppFEV1, CFQ-R RD, and sweat chloride concentrations in patients with CF. However, caution should be exercised regarding the incidence of AEs, particularl...
Caveolae constitute membrane microdomains where receptors and ion channels functionally interact. Caveolin-3 (cav-3) is the key structural component of muscular caveolae. Mutations in...
Autosomal dominant polycystic kidney disease (ADPKD) is a monogenic disease characterized by the accumulation of fluid-filled cysts in the kidneys, leading to renal volume enlargement and progressive ...
We established a single center retrospective cohort study in Kuwait where we followed every patient with a confirmed PKD1-ADPKD diagnosis clinically and genetically. Renal function tests were performe...
The study included 22 truncating and 20 non-truncating (42 total) patients followed for an average of 6.6 years (range: 1 to 12 years). Those with PKD1 truncating mutations had a more rapid rate of eG...
In longitudinal and survival analyses, patients with PKD1 truncating mutations showed a faster decline in kidney function compared to patients PKD1 non-truncating mutations. Early identification of pa...
There is preliminary evidence suggesting that FCR is a major problem for breast cancer survivors carrying a BRCA1/2 mutation. The goal of this qualitative study, conducted among women who were treated...
Three focus groups (90-110 min) were conducted with 19 breast cancer survivors carrying a BRCA1/2 mutation. The semistructured interview probed FCR level and impact, the role FCR played in the decisio...
Findings indicated that FCR was a significant issue in these women, even though a majority had undergone a prophylactic surgery. Patients strongly affirmed the need to develop and provide access to FC...
These results suggest that, although being the most effective medical option to reduce the actual risk of local recurrence (or second breast cancer), prophylactic surgery only partially reduces FCR. A...
POLE driver mutations in the exonuclease domain (ExoD driver) are prevalent in several cancers, including colorectal cancer (CRC) and endometrial cancer (EC), leading to dramatically ultra-high tumor ...
Serine/threonine kinase 11 (STK11), a tumor suppressor gene, exhibits frequent mutations in lung adenocarcinoma (LUAD). However, the specific molecular mechanisms by which STK11 mutations exert an inf...
Al Kaissi syndrome, a rare autosomal recessive genetic disorder, is characterized by intellectual disability, abnormal facial features, growth retardation, and spinal deformity, caused by CDK10 mutati...