Titre : Oxygène singulet

Oxygène singulet : Questions médicales fréquentes

Termes MeSH sélectionnés :

Multicenter Studies as Topic
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Oxygène singulet : Questions médicales les plus fréquentes", "headline": "Oxygène singulet : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Oxygène singulet : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-07-03", "dateModified": "2025-03-30", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Oxygène singulet" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Produits chimiques inorganiques", "url": "https://questionsmedicales.fr/mesh/D007287", "about": { "@type": "MedicalCondition", "name": "Produits chimiques inorganiques", "code": { "@type": "MedicalCode", "code": "D007287", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D01" } } }, "about": { "@type": "MedicalCondition", "name": "Oxygène singulet", "alternateName": "Singlet Oxygen", "code": { "@type": "MedicalCode", "code": "D026082", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Engin U Akkaya", "url": "https://questionsmedicales.fr/author/Engin%20U%20Akkaya", "affiliation": { "@type": "Organization", "name": "State Key Laboratory of Fine Chemicals, Department of Pharmacy, Dalian University of Technology 2 Linggong Road 116024 Dalian China." } }, { "@type": "Person", "name": "Lei Wang", "url": "https://questionsmedicales.fr/author/Lei%20Wang", "affiliation": { "@type": "Organization", "name": "State Key Laboratory of Fine Chemicals, and Department of Pharmaceutical Science, Dalian University of Technology, 2 Linggong Road, 116024, Dalian, China." } }, { "@type": "Person", "name": "Andrej Hovan", "url": "https://questionsmedicales.fr/author/Andrej%20Hovan", "affiliation": { "@type": "Organization", "name": "Department of Biophysics, Faculty of Science, P. J. Šafárik University in Košice, Jesenná 5, 041 54 Košice, Slovakia." } }, { "@type": "Person", "name": "Gregor Bánó", "url": "https://questionsmedicales.fr/author/Gregor%20B%C3%A1n%C3%B3", "affiliation": { "@type": "Organization", "name": "Department of Biophysics, Faculty of Science, P. J. Šafárik University in Košice, Jesenná 5, 041 54 Košice, Slovakia." } }, { "@type": "Person", "name": "Kristopher McNeill", "url": "https://questionsmedicales.fr/author/Kristopher%20McNeill", "affiliation": { "@type": "Organization", "name": "Institute of Biogeochemistry and Pollutant Dynamics (IBP), Department of Environmental Systems Science, ETH Zurich, 8092 Zurich, Switzerland." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "Incidence, risk factors and outcome of acute kidney injury in critically ill COVID-19 patients in Tyrol, Austria: a prospective multicenter registry study.", "datePublished": "2023-10-14", "url": "https://questionsmedicales.fr/article/37837501", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1007/s40620-023-01760-3" } }, { "@type": "ScholarlyArticle", "name": "Artificial intelligence-enhanced 12-lead electrocardiography for identifying atrial fibrillation during sinus rhythm (AIAFib) trial: protocol for a multicenter retrospective study.", "datePublished": "2023-10-11", "url": "https://questionsmedicales.fr/article/37886735", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3389/fcvm.2023.1258167" } }, { "@type": "ScholarlyArticle", "name": "Transarterial Chemoembolization Plus Lenvatinib and PD-1 Inhibitors for Hepatocellular Carcinoma with Main Trunk Portal Vein Tumor Thrombus: A Multicenter Retrospective Study.", "datePublished": "2023-10-11", "url": "https://questionsmedicales.fr/article/37850080", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.2147/JHC.S428980" } }, { "@type": "ScholarlyArticle", "name": "The impact of a structured assessment and decision tool (I-DECIDED®) on improving care of peripheral intravenous catheters: A multicenter, interrupted time-series study.", "datePublished": "2023-09-09", "url": "https://questionsmedicales.fr/article/37801935", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.ijnurstu.2023.104604" } }, { "@type": "ScholarlyArticle", "name": "A Longitudinal MRI-Based Artificial Intelligence System to Predict Pathological Complete Response After Neoadjuvant Therapy in Rectal Cancer: A Multicenter Validation Study.", "datePublished": "2023-09-08", "url": "https://questionsmedicales.fr/article/37682775", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1097/DCR.0000000000002931" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Produits chimiques inorganiques", "item": "https://questionsmedicales.fr/mesh/D007287" }, { "@type": "ListItem", "position": 3, "name": "Oxygène singulet", "item": "https://questionsmedicales.fr/mesh/D026082" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Oxygène singulet - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Oxygène singulet", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-16", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Oxygène singulet", "description": "Comment détecter l'oxygène singulet ?\nQuels tests mesurent l'oxygène singulet ?\nL'oxygène singulet est-il mesurable dans le sang ?\nQuels indicateurs biologiques sont liés à l'oxygène singulet ?\nPeut-on évaluer l'oxygène singulet par imagerie ?", "url": "https://questionsmedicales.fr/mesh/D026082?mesh_terms=Multicenter+Studies+as+Topic&page=1000#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Oxygène singulet", "description": "Quels symptômes sont associés à l'oxygène singulet ?\nL'oxygène singulet provoque-t-il des maladies ?\nQuels effets l'oxygène singulet a-t-il sur les cellules ?\nL'oxygène singulet affecte-t-il la peau ?\nY a-t-il des symptômes respiratoires liés à l'oxygène singulet ?", "url": "https://questionsmedicales.fr/mesh/D026082?mesh_terms=Multicenter+Studies+as+Topic&page=1000#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Oxygène singulet", "description": "Comment réduire l'exposition à l'oxygène singulet ?\nL'alimentation peut-elle prévenir les effets de l'oxygène singulet ?\nLe tabagisme augmente-t-il les risques liés à l'oxygène singulet ?\nLe stress oxydatif peut-il être évité ?\nLes exercices physiques aident-ils à prévenir les effets de l'oxygène singulet ?", "url": "https://questionsmedicales.fr/mesh/D026082?mesh_terms=Multicenter+Studies+as+Topic&page=1000#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Oxygène singulet", "description": "Comment traiter les effets de l'oxygène singulet ?\nY a-t-il des médicaments spécifiques pour l'oxygène singulet ?\nLes thérapies photodynamiques utilisent-elles l'oxygène singulet ?\nComment prévenir les dommages causés par l'oxygène singulet ?\nLes suppléments antioxydants sont-ils efficaces ?", "url": "https://questionsmedicales.fr/mesh/D026082?mesh_terms=Multicenter+Studies+as+Topic&page=1000#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Oxygène singulet", "description": "Quelles complications peuvent survenir avec l'oxygène singulet ?\nL'oxygène singulet peut-il causer des cancers ?\nY a-t-il des effets à long terme de l'oxygène singulet ?\nL'oxygène singulet affecte-t-il le système immunitaire ?\nDes troubles respiratoires peuvent-ils être causés par l'oxygène singulet ?", "url": "https://questionsmedicales.fr/mesh/D026082?mesh_terms=Multicenter+Studies+as+Topic&page=1000#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Oxygène singulet", "description": "Quels sont les facteurs de risque liés à l'oxygène singulet ?\nL'âge est-il un facteur de risque pour l'oxygène singulet ?\nLe stress oxydatif est-il un facteur de risque ?\nLes maladies préexistantes augmentent-elles les risques ?\nL'exposition à des produits chimiques est-elle un risque ?", "url": "https://questionsmedicales.fr/mesh/D026082?mesh_terms=Multicenter+Studies+as+Topic&page=1000#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment détecter l'oxygène singulet ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "L'oxygène singulet peut être détecté par des méthodes spectroscopiques comme la fluorescence." } }, { "@type": "Question", "name": "Quels tests mesurent l'oxygène singulet ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests de chimiluminescence et de spectroscopie UV-visible sont utilisés." } }, { "@type": "Question", "name": "L'oxygène singulet est-il mesurable dans le sang ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Non, il n'est pas mesurable directement dans le sang, mais ses effets peuvent l'être." } }, { "@type": "Question", "name": "Quels indicateurs biologiques sont liés à l'oxygène singulet ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Les marqueurs de stress oxydatif, comme les produits de peroxydation, peuvent indiquer sa présence." } }, { "@type": "Question", "name": "Peut-on évaluer l'oxygène singulet par imagerie ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines techniques d'imagerie peuvent indirectement évaluer son activité dans les tissus." } }, { "@type": "Question", "name": "Quels symptômes sont associés à l'oxygène singulet ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "L'oxygène singulet peut causer des dommages cellulaires, entraînant inflammation et douleur." } }, { "@type": "Question", "name": "L'oxygène singulet provoque-t-il des maladies ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, il est impliqué dans des maladies comme le cancer et les maladies neurodégénératives." } }, { "@type": "Question", "name": "Quels effets l'oxygène singulet a-t-il sur les cellules ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Il peut induire des lésions oxydatives, affectant la fonction cellulaire et la survie." } }, { "@type": "Question", "name": "L'oxygène singulet affecte-t-il la peau ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, il peut provoquer un vieillissement cutané prématuré et des dommages aux cellules de la peau." } }, { "@type": "Question", "name": "Y a-t-il des symptômes respiratoires liés à l'oxygène singulet ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Des dommages aux tissus pulmonaires peuvent survenir, entraînant des symptômes respiratoires." } }, { "@type": "Question", "name": "Comment réduire l'exposition à l'oxygène singulet ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Éviter les environnements pollués et utiliser des antioxydants peut aider à réduire l'exposition." } }, { "@type": "Question", "name": "L'alimentation peut-elle prévenir les effets de l'oxygène singulet ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une alimentation riche en fruits et légumes antioxydants peut aider à prévenir les dommages." } }, { "@type": "Question", "name": "Le tabagisme augmente-t-il les risques liés à l'oxygène singulet ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le tabagisme génère des radicaux libres, augmentant les effets nocifs de l'oxygène singulet." } }, { "@type": "Question", "name": "Le stress oxydatif peut-il être évité ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Réduire le stress, avoir une bonne hygiène de vie et consommer des antioxydants aide à prévenir." } }, { "@type": "Question", "name": "Les exercices physiques aident-ils à prévenir les effets de l'oxygène singulet ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exercice régulier peut améliorer la défense antioxydante de l'organisme." } }, { "@type": "Question", "name": "Comment traiter les effets de l'oxygène singulet ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Des antioxydants peuvent être utilisés pour neutraliser les effets nocifs de l'oxygène singulet." } }, { "@type": "Question", "name": "Y a-t-il des médicaments spécifiques pour l'oxygène singulet ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Il n'existe pas de médicaments spécifiques, mais des traitements antioxydants sont recommandés." } }, { "@type": "Question", "name": "Les thérapies photodynamiques utilisent-elles l'oxygène singulet ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elles exploitent l'oxygène singulet pour détruire les cellules cancéreuses." } }, { "@type": "Question", "name": "Comment prévenir les dommages causés par l'oxygène singulet ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "L'utilisation d'antioxydants et la réduction de l'exposition aux polluants peuvent aider." } }, { "@type": "Question", "name": "Les suppléments antioxydants sont-ils efficaces ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Ils peuvent réduire les effets de l'oxygène singulet, mais leur efficacité varie selon les individus." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec l'oxygène singulet ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications incluent des maladies cardiovasculaires et des troubles neurodégénératifs." } }, { "@type": "Question", "name": "L'oxygène singulet peut-il causer des cancers ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, il est impliqué dans la formation de radicaux libres, augmentant le risque de cancer." } }, { "@type": "Question", "name": "Y a-t-il des effets à long terme de l'oxygène singulet ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Des effets à long terme incluent le vieillissement cellulaire et des maladies chroniques." } }, { "@type": "Question", "name": "L'oxygène singulet affecte-t-il le système immunitaire ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, il peut altérer la fonction immunitaire, rendant l'organisme plus vulnérable aux infections." } }, { "@type": "Question", "name": "Des troubles respiratoires peuvent-ils être causés par l'oxygène singulet ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, il peut provoquer des lésions pulmonaires, entraînant des troubles respiratoires." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque liés à l'oxygène singulet ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent le tabagisme, la pollution, et une alimentation pauvre en antioxydants." } }, { "@type": "Question", "name": "L'âge est-il un facteur de risque pour l'oxygène singulet ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le vieillissement augmente la susceptibilité aux dommages causés par l'oxygène singulet." } }, { "@type": "Question", "name": "Le stress oxydatif est-il un facteur de risque ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un stress oxydatif accru peut augmenter les effets nocifs de l'oxygène singulet." } }, { "@type": "Question", "name": "Les maladies préexistantes augmentent-elles les risques ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des maladies comme le diabète et les maladies cardiovasculaires augmentent les risques." } }, { "@type": "Question", "name": "L'exposition à des produits chimiques est-elle un risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exposition à des produits chimiques toxiques peut augmenter la production d'oxygène singulet." } } ] } ] }

Sources (10000 au total)

Incidence, risk factors and outcome of acute kidney injury in critically ill COVID-19 patients in Tyrol, Austria: a prospective multicenter registry study.

Acute kidney injury is a frequent complication in critically ill patients with and without COVID-19. The aim of this study was to evaluate the incidence of, and risk factors for, acute kidney injury a... This multicenter prospective registry study included adult patients with a SARS-CoV-2 infection confirmed by polymerase chain reaction, who were treated in one of the 12 dedicated intensive care units... In total, 1042 patients were included during the study period. The median age of the overall cohort was 66 years. Of the included patients, 267 (26%) developed acute kidney injury during their intensi... As in non-COVID-19 patients, acute kidney injury is clearly associated with increased mortality in critically ill COVID-19 patients. Among known risk factors, invasive mechanical ventilation has been ...

Artificial intelligence-enhanced 12-lead electrocardiography for identifying atrial fibrillation during sinus rhythm (AIAFib) trial: protocol for a multicenter retrospective study.

Atrial fibrillation (AF) is the most common arrhythmia, contributing significantly to morbidity and mortality. In a previous study, we developed a deep neural network for predicting paroxysmal atrial ... We will conduct a retrospective cohort study of more than 50,000 12-lead ECGs from November 1, 2012, to December 31, 2021, at 10 Korean University Hospitals. Data will be collected from patient record... This study will advance PAF prediction based on AI-enhanced ECGs. This approach is a novel method for risk stratification and emphasizes shared decision-making for early detection and management of pa... The study findings will be published in peer-reviewed publications and disseminated at national and international conferences and through social media. This study was approved by the institutional rev... [cris.nih.go.kr], identifier (KCT0007881)....

Transarterial Chemoembolization Plus Lenvatinib and PD-1 Inhibitors for Hepatocellular Carcinoma with Main Trunk Portal Vein Tumor Thrombus: A Multicenter Retrospective Study.

In recent years, immune checkpoint inhibitors have been used in combination with tyrosine kinase inhibitors and local therapies, creating a new era in treating hepatocellular carcinoma (HCC) with port... This study enrolled patients receiving triple therapy at four institutions between August 2018 and April 2022. Patient characteristics and course of treatment were extracted from patient records. Tumo... Median follow-up duration was 18 (4.0-26.3) months. Overall, 41 patients with HCC and Vp4 receiving first-line triple therapy were enrolled. The intrahepatic tumor objective response rate was 68.3%. T... TACE plus lenvatinib and PD-1 inhibition was effective and tolerable for treating unresectable HCC with Vp4, with a high tumor response rate and favorable prognosis....

The impact of a structured assessment and decision tool (I-DECIDED®) on improving care of peripheral intravenous catheters: A multicenter, interrupted time-series study.

Peripheral intravenous catheters are the most widely used invasive device in hospitals but have serious risks.... To determine if a structured assessment and decision tool (I-DECIDED®) improves daily peripheral intravenous catheter assessment and care decisions.... Prospective, interrupted time-series study.... Seven adult inpatient wards in three Australian hospitals.... 825 adults with 867 peripheral intravenous catheters.... Between August 2017 and December 2018, peripheral intravenous catheter assessments and chart audits were undertaken with informed patient consent. Following a 4-month pre-intervention period (with 2-w... Of 2055 patients screened, 1175 (57.2%) had a peripheral intravenous catheter, and 825 patients (867 catheters) consented and were included in the final analysis. Device utilization increased from 42.... Implementation of a comprehensive device assessment and decision tool (I-DECIDED®) reduced idle catheters and catheter complications, despite higher device utilization. Dressing quality improved but w... ACTRN12617000067370. Date of registration 13 January 2017. Date of first data collection 3rd August 2017.... #IDECIDEDassessment reduces prevalence of idle peripheral catheters and device complications....

A Longitudinal MRI-Based Artificial Intelligence System to Predict Pathological Complete Response After Neoadjuvant Therapy in Rectal Cancer: A Multicenter Validation Study.

Accurate prediction of response to neoadjuvant chemoradiotherapy is critical for subsequent treatment decisions for patients with locally advanced rectal cancer.... To develop and validate a deep learning model based on the comparison of paired MRI before and after neoadjuvant chemoradiotherapy to predict pathological complete response.... By capturing the changes from MRI before and after neoadjuvant chemoradiotherapy in 638 patients, we trained a multitask deep learning model for response prediction (DeepRP-RC) that also allowed simul... Multicenter study.... We retrospectively enrolled 1201 patients diagnosed with locally advanced rectal cancer who underwent neoadjuvant chemoradiotherapy before total mesorectal excision. Patients had been treated at 1 of ... The main outcome was the accuracy of predicting pathological complete response, measured as the area under receiver operating curve for the training and validation data sets.... DeepRP-RC achieved high performance in predicting pathological complete response after neoadjuvant chemoradiotherapy, with area under the curve values of 0.969 (0.942-0.996), 0.946 (0.915-0.977), 0.94... This study was limited by its retrospective design and absence of multiethnic data.... DeepRP-RC could be an accurate preoperative tool for pathological complete response prediction in rectal cancer after neoadjuvant chemoradiotherapy.... ANTECEDENTES:La predicción precisa de la respuesta a la quimiorradioterapia neoadyuvante es fundamental para las decisiones de tratamiento posteriores para los pacientes con cáncer de recto localmente...

Infarct severity and outcomes in ST-elevation myocardial infarction patients without standard modifiable risk factors - A multicenter cardiac magnetic resonance study.

Standard modifiable cardiovascular risk factors (SMuRFs) are well-established players in the pathogenesis of ST-elevation myocardial infarction (STEMI). However, in a significant proportion of STEMI p... To assess the infarct characteristics at myocardial-tissue level and subsequent clinical outcomes in SMuRF-less STEMIs.... This multicenter, individual patient-data analysis included 2012 STEMI patients enrolled in four cardiac magnetic resonance (CMR) imaging studies conducted in Austria, Germany, Scotland, and the Nethe... No SMuRF was identified in 185 patients (9%). These SMuRF-less patients were older, more often male, had lower TIMI risk score and pre-interventional TIMI flow, and less frequently multivessel-disease... In this large individual patient-data pooled analysis of low-risk STEMI patients, infarct characteristics and clinical outcomes were not different according to SMuRF status....

MesenchymAl stromal cells for Traumatic bRain Injury (MATRIx): a study protocol for a multicenter, double-blind, randomised, placebo-controlled phase II trial.

Traumatic brain injury (TBI) is a significant cause of death and disability, with no effective neuroprotective drugs currently available for its treatment. Mesenchymal stromal cell (MSC)-based therapy... The study will be conducted in two steps. Step 1 will enrol 42 patients, randomised in a 1:1:1 ratio to receive 80 million MSCs, 160 million MSCs or a placebo to establish safety and identify the most... Overall, the MATRIx trial is a critical step towards developing an effective treatment for TBI, which could significantly improve the lives of millions worldwide affected by this debilitating conditio...

Adoptive Immunotherapy via Donor Lymphocyte Infusions following Allogeneic Hematopoietic Stem Cell Transplantation for Myelofibrosis: A Real-World, Retrospective Multicenter Study.

Allogeneic hematopoietic cell transplantation (allo-HCT) remains the sole curative option for myelofibrosis (MF). Relapse remains a significant problem, however, occurring in up to 20% to 30% of cases...

Clinical Outcomes and Predictors of Long-Term Survival in Patients With and Without Previously Known Extracardiac Sarcoidosis Using Machine Learning: A Swedish Multicenter Study.

Background Cardiac involvement can be an initial manifestation in sarcoidosis. However, little is known about the association between various clinical phenotypes of cardiac sarcoidosis (CS) and outcom...