Les plantes de Ligusticum se caractérisent par leurs feuilles découpées et leurs fleurs blanches.
Plantes médicinalesPhytothérapie
#2
Quels tests pour évaluer l'efficacité du Ligusticum ?
Des études cliniques et des essais contrôlés randomisés sont nécessaires pour évaluer son efficacité.
Essais cliniquesEfficacité thérapeutique
Symptômes
2
#1
Quels symptômes le Ligusticum peut-il traiter ?
Il est utilisé pour soulager les douleurs, les inflammations et les troubles circulatoires.
DouleurInflammation
#2
Le Ligusticum provoque-t-il des effets secondaires ?
Des effets secondaires comme des nausées ou des réactions allergiques peuvent survenir.
Effets indésirablesRéactions allergiques
Prévention
2
#1
Le Ligusticum aide-t-il à prévenir les maladies cardiovasculaires ?
Il est parfois utilisé pour améliorer la circulation sanguine et réduire les risques cardiovasculaires.
Maladies cardiovasculairesCirculation sanguine
#2
Peut-on utiliser le Ligusticum en prévention des inflammations ?
Oui, il est souvent recommandé pour ses propriétés anti-inflammatoires.
InflammationPrévention
Traitements
2
#1
Comment utiliser le Ligusticum en phytothérapie ?
Il peut être utilisé sous forme de décoction, d'extrait ou de teinture mère.
PhytothérapieDécoction
#2
Le Ligusticum est-il efficace contre les migraines ?
Certaines études suggèrent qu'il peut réduire la fréquence des migraines.
MigraineTraitement
Complications
2
#1
Quelles complications peuvent survenir avec le Ligusticum ?
Des complications comme des troubles gastro-intestinaux peuvent se produire en cas de surdosage.
ComplicationsTroubles gastro-intestinaux
#2
Le Ligusticum interagit-il avec d'autres médicaments ?
Oui, il peut interagir avec des anticoagulants et d'autres médicaments affectant la coagulation.
Interactions médicamenteusesAnticoagulants
Facteurs de risque
2
#1
Qui devrait éviter le Ligusticum ?
Les femmes enceintes, allaitantes et les personnes allergiques aux plantes de la famille doivent éviter son usage.
GrossesseAllergies
#2
Le Ligusticum est-il sûr pour les enfants ?
Son utilisation chez les enfants n'est pas bien étudiée, il est donc conseillé de consulter un médecin.
EnfantsSécurité
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State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. Electronic address: pengcheng@cdutcm.edu.cn.
State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China; Institute of Innovative Medicine Ingredients of Southwest Specialty Medicinal Materials, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. Electronic address: xiling@cdutcm.edu.cn.
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China. Electronic address: pczhang@imm.ac.cn.
School of Pharmacy, Chengdu University of Traditional Chinese Medicine Chengdu 611137, China State Key Laboratory of Southwestern Chinese Medicine Resources Chengdu 611137, China.
State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China; Institute of Innovative Medicine Ingredients of Southwest Specialty Medicinal Materials, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
National Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Jiangsu Provincial Key Construction Laboratory of Special Biomass Waste Resource Utilization, School of Food Science, Nanjing Xiaozhuang University, Nanjing, 211117, China.
National Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing 210023, China.
School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
Chuanxiong, the rhizome of Ligusticum chuanxiong Hort., is an ancient herbal medicine that has gained extensive popularity in alleviating migraines with satisfying therapeutic effects in China. As the...
To explore the anti-neuroinflammatory properties of Chuanxiong essential oil and its molecular mechanisms by network pharmacology analysis and in vitro experiments....
Gas chromatography-mass spectrometry (GC-MS) was used to identify the chemical components of Chuanxiong essential oil. Public databases were used to predict possible targets, build the protein-protein...
Thirty-six compounds were identified from Chuanxiong essential oil by GC-MS, and their corresponding putative targets were predicted. The network pharmacology study identified 232 candidate targets of...
Chuanxiong essential oil alleviates neuroinflammation through the NF-κB signaling pathway, which provides a theoretical foundation for a better understanding of the clinical application of Chuanxiong ...
Conioselinum anthriscoides (H. Boissieu) Pimenov & Kljuykov, also known as Ligusticum chuanxiong Hort. is a perennial Umbelliferae herb, whose dried rhizome commonly called Chuanxiong Rhizoma. Chuanxi...
The purpose of this review is to summarize the current experimental studies on Chuanxiong Rhizoma and explore its mechanism of action....
Web of Science, PubMed, CBM, CNKI, Medline, Embase, Elsevier, Springer, Wiley Online Library, Scholar, and other databases were searched, and nearly one hundred experimental studies were collected to ...
Chuanxiong Rhizoma is composed of essential oil, terpenes, alkaloids, polysaccharide, organic acids, ceramides, and cerebrosides. It has the functions of promoting blood circulation, removing blood st...
In the past 20 years, a large number of research data have confirmed that Chuanxiong Rhizoma contains rich effective metabolites, has huge medicinal potential, and has a wide range of effective treatm...
In our program of screening natural products against the pests of medical and veterinary importance, ethanolic extract of the roots of Ligusticum porteri J.M.Coult. & Rose showed significant repellenc...
Ligusticum chuanxiong hort. (Chuanxiong, CX) is a well-known traditional edible-medicinal herb, especially in brain diseases. However, there is a lack of studies focusing on the action of CX in metabo...
To investigate the action of the aqueous extract of CX (LCH) on nitroglycerin (NTG)-induced migraine....
The effects and mechanisms of LCH on migraine were evaluated in NTG-induced mice and rats. Laser speckle contrast imaging was performed to detect the cerebral blood flow. Metabolomic analysis in serum...
Totally, 1480 metabolites were identified, among which, 50 and 49 differential metabolites were identified by t-test, fold change, and VIP score for NTG vs. CON and LCH+NTG vs. NTG, respectively. Next...
To sum up, the present study firstly reveals that LCH plays a therapeutic role for migraine through glucose-glutamate-Nrf-2 axis, which might represent a promising approach in the development of advan...
Falonolide A (1) and B (2), two novel polyyne hybrid phthalides resulting from unprecedented carbon skeleton polymerized by Z-ligustilide and falcarindiol, along with six new related phthalides (3-8),...
As the most famous and widely used traditional Chinese medicine (TCM), Ligusticum sinense cv. Chuanxiong (L. Chuaniong) has been affected by cadmium (Cd) exceeding with high ability of Cd accumulation...
Ligusticum striatum DC. (LDC) is often prescribed for Cerebral Ischemia (CI) and is commonly combined with Borneolum (BO) to enhance therapeutic outcomes. However, its specific active ingredients and ...
This study aimed to identify the active ingredients and mechanisms of LDC and BO combination therapy against CI using network pharmacology, molecular docking, and in vivo experiments....
Potential active ingredients and targets were sourced from relevant databases, and a drug-component-target-disease network was constructed to pinpoint key ingredients. Subsequently, a protein-protein ...
Venn analysis identified a total of 41 components and 292 potential targets. The drugcomponent-target-disease network revealed that the key components in LDC were palmitic acid, tetramethylpyrazine, a...
The combination of LDC and BO markedly improved CI and inhibited inflammation response via activating the PI3K/AKT pathway....
Ligusticum Chuanxiong is an essential medicinal and edible plant, but it is highly susceptible to the enrichment of soil Cadmium (Cd), which seriously affects its medical safety. However, the control ...
Ligusticum chuanxiong Hort (LCH), with the accepted name of Ligusticum striatum DC in "The Plant List" database, is a widely used ethnomedicine in treating ischemic stroke, and borneol (BO) is usually...
More and more evidence indicated that astrocytes (ACs) might be involved in the modulation of neurogenesis via polarization reaction. The study was designed to explore the synergic mechanism between L...
After primary cultures and identifications of ACs and neural stem cells (NSCs), the oxygen-glucose deprivation (OGD) model and the concentrations of LCH and BO were optimized. After the OGD-injured AC...
The most appropriate duration of OGD for the injury of both NSCs and ACs was 6 h, and the optimized concentrations of LCH and BO were 1.30 μg/mL and 0.03 μg/mL, respectively. The moderate OGD environm...
A certain degree of OGD might induce ACs to stimulate the proliferation, astrogenesis, and neurogenesis of NSCs. LCH and BO exhibited a marked synergy in promoting ACs-mediated neurogenesis and reduci...
Ligusticum chuanxiong Hort., with over 2000 years of medicinal use and cultivation history, is extensively used in clinical settings for treating heart disease, headache, dysmenorrhea, and amenorrhea....
The results reveal that the predominant environmental factors influencing the distribution were the minimum temperature of the coldest month (Bio6) and solar radiation (Srad), with cumulative account ...
These findings contribute to an enhanced understanding of how environmental factors impact the distribution and quality of medicinal plants and offer a theoretical reference for the introduction, cult...
