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Facteurs biologiques
Protéines et peptides de signalisation intercellulaire
Éphrines
Éphrine A3
Éphrine A3 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Angiotensin II Type 2 Receptor Blockers
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"name": "Diagnostic",
"headline": "Diagnostic sur Éphrine A3",
"description": "Comment diagnostiquer une anomalie d'éphrine A3 ?\nQuels examens sont recommandés pour évaluer l'éphrine A3 ?\nY a-t-il des biomarqueurs associés à l'éphrine A3 ?\nQuels symptômes peuvent indiquer un problème avec l'éphrine A3 ?\nPeut-on utiliser l'imagerie pour évaluer l'éphrine A3 ?",
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"headline": "Symptômes sur Éphrine A3",
"description": "Quels sont les symptômes d'une dysfonction d'éphrine A3 ?\nL'éphrine A3 est-elle liée à des maladies spécifiques ?\nComment l'éphrine A3 affecte-t-elle le système nerveux ?\nDes troubles comportementaux peuvent-ils être liés à l'éphrine A3 ?\nL'éphrine A3 influence-t-elle le développement cérébral ?",
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"headline": "Prévention sur Éphrine A3",
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"headline": "Traitements sur Éphrine A3",
"description": "Quels traitements ciblent l'éphrine A3 ?\nPeut-on modifier l'expression de l'éphrine A3 ?\nY a-t-il des essais cliniques sur l'éphrine A3 ?\nQuels médicaments peuvent affecter l'éphrine A3 ?\nL'éphrine A3 peut-elle être une cible thérapeutique ?",
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"description": "Quelles complications peuvent survenir avec l'éphrine A3 ?\nL'éphrine A3 est-elle impliquée dans des cancers ?\nDes troubles cognitifs peuvent-ils être des complications ?\nComment les complications sont-elles gérées ?\nY a-t-il des risques de récidive avec l'éphrine A3 ?",
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"@type": "Question",
"name": "Comment diagnostiquer une anomalie d'éphrine A3 ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques et des analyses de tissus peuvent être utilisés pour détecter des anomalies."
}
},
{
"@type": "Question",
"name": "Quels examens sont recommandés pour évaluer l'éphrine A3 ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'immunohistochimie et la PCR sont souvent utilisés pour évaluer l'expression de l'éphrine A3."
}
},
{
"@type": "Question",
"name": "Y a-t-il des biomarqueurs associés à l'éphrine A3 ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'éphrine A3 elle-même peut servir de biomarqueur dans certaines pathologies neurologiques."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent indiquer un problème avec l'éphrine A3 ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles neurologiques ou des anomalies de développement peuvent indiquer un problème."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser l'imagerie pour évaluer l'éphrine A3 ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'imagerie cérébrale peut aider à visualiser des anomalies associées à des dysfonctionnements de l'éphrine A3."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une dysfonction d'éphrine A3 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent inclure des troubles cognitifs, des problèmes de coordination et des retards de développement."
}
},
{
"@type": "Question",
"name": "L'éphrine A3 est-elle liée à des maladies spécifiques ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies d'éphrine A3 sont associées à des maladies neurodégénératives et des cancers."
}
},
{
"@type": "Question",
"name": "Comment l'éphrine A3 affecte-t-elle le système nerveux ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle joue un rôle dans la formation des synapses et la plasticité neuronale, influençant le comportement."
}
},
{
"@type": "Question",
"name": "Des troubles comportementaux peuvent-ils être liés à l'éphrine A3 ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des dysfonctionnements de l'éphrine A3 peuvent entraîner des troubles du comportement."
}
},
{
"@type": "Question",
"name": "L'éphrine A3 influence-t-elle le développement cérébral ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle est essentielle pour le développement normal des circuits neuronaux dans le cerveau."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les troubles liés à l'éphrine A3 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention passe par une détection précoce et une intervention dans les cas à risque."
}
},
{
"@type": "Question",
"name": "Y a-t-il des facteurs environnementaux influençant l'éphrine A3 ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des facteurs environnementaux comme la nutrition et les toxines peuvent influencer son expression."
}
},
{
"@type": "Question",
"name": "Comment le mode de vie affecte-t-il l'éphrine A3 ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain peut favoriser une expression normale de l'éphrine A3 et réduire les risques."
}
},
{
"@type": "Question",
"name": "Des conseils nutritionnels peuvent-ils aider ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée riche en nutriments peut soutenir la santé neuronale et l'éphrine A3."
}
},
{
"@type": "Question",
"name": "L'éducation prénatale peut-elle prévenir des troubles ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'éducation prénatale sur les risques environnementaux peut aider à prévenir des troubles liés à l'éphrine A3."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent l'éphrine A3 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies géniques et des médicaments ciblant les voies de signalisation peuvent être envisagés."
}
},
{
"@type": "Question",
"name": "Peut-on modifier l'expression de l'éphrine A3 ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des approches pharmacologiques peuvent moduler l'expression de l'éphrine A3 dans certaines conditions."
}
},
{
"@type": "Question",
"name": "Y a-t-il des essais cliniques sur l'éphrine A3 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des essais cliniques sont en cours pour évaluer des traitements ciblant l'éphrine A3 dans diverses pathologies."
}
},
{
"@type": "Question",
"name": "Quels médicaments peuvent affecter l'éphrine A3 ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments anticancéreux et neuroprotecteurs peuvent influencer l'activité de l'éphrine A3."
}
},
{
"@type": "Question",
"name": "L'éphrine A3 peut-elle être une cible thérapeutique ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, en raison de son rôle dans diverses maladies, elle est considérée comme une cible thérapeutique potentielle."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec l'éphrine A3 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications neurologiques et des troubles de développement peuvent survenir en cas d'anomalies."
}
},
{
"@type": "Question",
"name": "L'éphrine A3 est-elle impliquée dans des cancers ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies d'éphrine A3 sont associées à certains types de cancers, notamment le gliome."
}
},
{
"@type": "Question",
"name": "Des troubles cognitifs peuvent-ils être des complications ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des dysfonctionnements de l'éphrine A3 peuvent entraîner des troubles cognitifs sévères."
}
},
{
"@type": "Question",
"name": "Comment les complications sont-elles gérées ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion des complications implique des traitements symptomatiques et des interventions ciblées."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de récidive avec l'éphrine A3 ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des risques de récidive peuvent exister dans les cas de cancers associés à des anomalies d'éphrine A3."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour l'éphrine A3 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs génétiques, environnementaux et le mode de vie peuvent influencer le risque d'anomalies."
}
},
{
"@type": "Question",
"name": "L'hérédité joue-t-elle un rôle dans les troubles d'éphrine A3 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de troubles neurologiques peuvent augmenter le risque d'anomalies."
}
},
{
"@type": "Question",
"name": "Les toxines environnementales affectent-elles l'éphrine A3 ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certaines toxines peut perturber l'expression de l'éphrine A3."
}
},
{
"@type": "Question",
"name": "Le stress peut-il influencer l'éphrine A3 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut affecter la signalisation de l'éphrine A3 et la santé neuronale."
}
},
{
"@type": "Question",
"name": "Y a-t-il des prédispositions génétiques pour l'éphrine A3 ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines variations génétiques peuvent prédisposer les individus à des troubles liés à l'éphrine A3."
}
}
]
}
]
}
Animal and human studies have suggested that the use of angiotensin receptor blockers (ARBs) may be associated with a lower risk of incident epilepsy compared with other antihypertensive medications. ...
To evaluate the association between ARB use and epilepsy incidence in subgroups of US patients with hypertension....
This retrospective cohort study used data from a national health administrative database from January 2010 to December 2017 with propensity score (PS) matching. The eligible cohort included privately ...
Propensity scores were generated based on baseline covariates and used to match patients who received ARBs with those who received either ACEIs, β-blockers, CCBs, or a combination of these antihyperte...
Cox regression analyses were used to evaluate epilepsy incidence during follow-up comparing the ARB cohort with other antihypertensive classes. Subgroup and sensitivity analyses were conducted to exam...
Of 2 261 964 patients (mean [SD] age, 61.7 [13.9] years; 1 120 630 [49.5%] female) included, 309 978 received ARBs, 807 510 received ACEIs, 695 887 received β-blockers, and 448 589 received CCBs. Demo...
This cohort study found that ARBs, mainly losartan, were associated with a lower incidence of epilepsy compared with other antihypertensive agents in hypertensive patients with no preexisting stroke o...
Alzheimer's disease (AD) and dementia are preventable and highly prevalent diseases, as is systemic arterial hypertension. Thus, it is speculated that angiotensin receptor blockers (ARBs) may be neuro...
The aim of this study was to evaluate if the use of ARBs confers a neuroprotective effect on AD, through a systematic review....
Studies published on Embase, LILACS, SciELO, and PubMed were evaluated. The selection of the studies included those that evaluated the use of antihypertensive drugs in individuals with a previous diag...
A total of 12 articles were identified, and 3 articles were selected. Two of them analyzed the use of ARB/ACEI versus other antihypertensives and the development of dementia....
There is a tendency for ARBs to be superior to other antihypertensives in preventing dementia....
Hypertension is a known risk factor for cognition-related pathologies including dementia. The National Institute of Health and Care Excellence (NICE) guidelines recommend angiotensin (Ang) II receptor...
Neurofibromatosis type 2 (NF-2) is a genetic condition that by definition includes bilateral vestibular schwannoma, a non-malignant lesion also known as acoustic neuroma. Patients often develop hearin...
Background PARAGON-HF (Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction) suggested a potential benefit of sacu...
Patients with acute myocardial infarction (AMI) are usually treated with angiotensin-converting enzyme inhibitors (ACEi) or angiotensin II receptor blockers (ARB). The aim of this meta-analysis is to ...
Despite the observation of synergistic interactions between the urotensinergic and angiotensinergic systems, the interplay between the urotensin II receptor (hUT) and the angiotensin II type 1 recepto...
The renin-angiotensin system in the brain plays a pivotal role in modulating sympathetic nerve activity and contributes to the pathogenesis of hypertension. Angiotensin II (Ang II) type 1 receptor (AT...
Although enteropathy due to angiotensin II receptor blockers (ARBs) has been known for over 10 years, clinicians' awareness of this condition is still low....
To systematically review the literature about clinical phenotypes, distribution of mucosal changes throughout the gastrointestinal tract and prognosis of enteropathy due to ARBs....
According to PRISMA guidelines, we searched PubMed and Embase for relevant articles up to November 6, 2023. We included full-text papers, letters, case reports and case series describing enteropathy d...
We included 94 articles reporting 183 cases (101 female, mean age at diagnosis 69 ± 10 years). The clinical picture at diagnosis was characterised by severe diarrhoea (97%) and weight loss (84%, media...
Enteropathy due to ARBs is characterised by severe malabsorption often requiring hospital admission and can involve the entire gastrointestinal tract. Clinician awareness can lead to prompt diagnosis ...
The antihypertensive effects of angiotensin II receptor blockers (ARBs) are well recognized. However, conventional meta-analyses have reported inconsistent results on their efficacy and safety....
This study aimed to evaluate the efficacy and safety of six ARBs (losartan, valsartan, irbesartan, telmisartan, candesartan, and olmesartan) commonly used to treat hypertension, using a network meta-a...
We retrieved randomized controlled trials on hypertension treatment using ARBs from the PubMed, Embase, Cochrane Library, CNKI, and Wanfang databases. The efficacy outcomes included absolute changes i...
A total of 193 studies were included. Olmesartan had the highest surface under the cumulative ranking in reducing office systolic (91.4%) and diastolic blood pressure (87.2%). Candesartan has the high...
Valsartan and losartan were less effective in lowering blood pressure than other drugs, with no significant differences. Olmesartan and telmisartan were associated with fewer AEs than losartan, althou...