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"description": "Comment diagnostiquer une anomalie d'éphrine A3 ?\nQuels examens sont recommandés pour évaluer l'éphrine A3 ?\nY a-t-il des biomarqueurs associés à l'éphrine A3 ?\nQuels symptômes peuvent indiquer un problème avec l'éphrine A3 ?\nPeut-on utiliser l'imagerie pour évaluer l'éphrine A3 ?",
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"@type": "Question",
"name": "Comment diagnostiquer une anomalie d'éphrine A3 ?",
"position": 1,
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"text": "Des tests génétiques et des analyses de tissus peuvent être utilisés pour détecter des anomalies."
}
},
{
"@type": "Question",
"name": "Quels examens sont recommandés pour évaluer l'éphrine A3 ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'immunohistochimie et la PCR sont souvent utilisés pour évaluer l'expression de l'éphrine A3."
}
},
{
"@type": "Question",
"name": "Y a-t-il des biomarqueurs associés à l'éphrine A3 ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'éphrine A3 elle-même peut servir de biomarqueur dans certaines pathologies neurologiques."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent indiquer un problème avec l'éphrine A3 ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles neurologiques ou des anomalies de développement peuvent indiquer un problème."
}
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"@type": "Question",
"name": "Peut-on utiliser l'imagerie pour évaluer l'éphrine A3 ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'imagerie cérébrale peut aider à visualiser des anomalies associées à des dysfonctionnements de l'éphrine A3."
}
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{
"@type": "Question",
"name": "Quels sont les symptômes d'une dysfonction d'éphrine A3 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent inclure des troubles cognitifs, des problèmes de coordination et des retards de développement."
}
},
{
"@type": "Question",
"name": "L'éphrine A3 est-elle liée à des maladies spécifiques ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies d'éphrine A3 sont associées à des maladies neurodégénératives et des cancers."
}
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{
"@type": "Question",
"name": "Comment l'éphrine A3 affecte-t-elle le système nerveux ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle joue un rôle dans la formation des synapses et la plasticité neuronale, influençant le comportement."
}
},
{
"@type": "Question",
"name": "Des troubles comportementaux peuvent-ils être liés à l'éphrine A3 ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des dysfonctionnements de l'éphrine A3 peuvent entraîner des troubles du comportement."
}
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{
"@type": "Question",
"name": "L'éphrine A3 influence-t-elle le développement cérébral ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle est essentielle pour le développement normal des circuits neuronaux dans le cerveau."
}
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{
"@type": "Question",
"name": "Peut-on prévenir les troubles liés à l'éphrine A3 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention passe par une détection précoce et une intervention dans les cas à risque."
}
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{
"@type": "Question",
"name": "Y a-t-il des facteurs environnementaux influençant l'éphrine A3 ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des facteurs environnementaux comme la nutrition et les toxines peuvent influencer son expression."
}
},
{
"@type": "Question",
"name": "Comment le mode de vie affecte-t-il l'éphrine A3 ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain peut favoriser une expression normale de l'éphrine A3 et réduire les risques."
}
},
{
"@type": "Question",
"name": "Des conseils nutritionnels peuvent-ils aider ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée riche en nutriments peut soutenir la santé neuronale et l'éphrine A3."
}
},
{
"@type": "Question",
"name": "L'éducation prénatale peut-elle prévenir des troubles ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'éducation prénatale sur les risques environnementaux peut aider à prévenir des troubles liés à l'éphrine A3."
}
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{
"@type": "Question",
"name": "Quels traitements ciblent l'éphrine A3 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies géniques et des médicaments ciblant les voies de signalisation peuvent être envisagés."
}
},
{
"@type": "Question",
"name": "Peut-on modifier l'expression de l'éphrine A3 ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des approches pharmacologiques peuvent moduler l'expression de l'éphrine A3 dans certaines conditions."
}
},
{
"@type": "Question",
"name": "Y a-t-il des essais cliniques sur l'éphrine A3 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des essais cliniques sont en cours pour évaluer des traitements ciblant l'éphrine A3 dans diverses pathologies."
}
},
{
"@type": "Question",
"name": "Quels médicaments peuvent affecter l'éphrine A3 ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments anticancéreux et neuroprotecteurs peuvent influencer l'activité de l'éphrine A3."
}
},
{
"@type": "Question",
"name": "L'éphrine A3 peut-elle être une cible thérapeutique ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, en raison de son rôle dans diverses maladies, elle est considérée comme une cible thérapeutique potentielle."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec l'éphrine A3 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications neurologiques et des troubles de développement peuvent survenir en cas d'anomalies."
}
},
{
"@type": "Question",
"name": "L'éphrine A3 est-elle impliquée dans des cancers ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies d'éphrine A3 sont associées à certains types de cancers, notamment le gliome."
}
},
{
"@type": "Question",
"name": "Des troubles cognitifs peuvent-ils être des complications ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des dysfonctionnements de l'éphrine A3 peuvent entraîner des troubles cognitifs sévères."
}
},
{
"@type": "Question",
"name": "Comment les complications sont-elles gérées ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion des complications implique des traitements symptomatiques et des interventions ciblées."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de récidive avec l'éphrine A3 ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des risques de récidive peuvent exister dans les cas de cancers associés à des anomalies d'éphrine A3."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour l'éphrine A3 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs génétiques, environnementaux et le mode de vie peuvent influencer le risque d'anomalies."
}
},
{
"@type": "Question",
"name": "L'hérédité joue-t-elle un rôle dans les troubles d'éphrine A3 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de troubles neurologiques peuvent augmenter le risque d'anomalies."
}
},
{
"@type": "Question",
"name": "Les toxines environnementales affectent-elles l'éphrine A3 ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certaines toxines peut perturber l'expression de l'éphrine A3."
}
},
{
"@type": "Question",
"name": "Le stress peut-il influencer l'éphrine A3 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut affecter la signalisation de l'éphrine A3 et la santé neuronale."
}
},
{
"@type": "Question",
"name": "Y a-t-il des prédispositions génétiques pour l'éphrine A3 ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines variations génétiques peuvent prédisposer les individus à des troubles liés à l'éphrine A3."
}
}
]
}
]
}
ChatGPT represents a potential resource for patient guidance and education, with the possibility for quality improvement in healthcare delivery. The present study evaluates the role of ChatGPT as an i...
Sixteen patient profiles were generated to simulate postoperative patient presentations, with complications of varying acuity and severity. ChatGPT was assessed for its accuracy in generating a differ...
Overall accuracy in providing a complete differential diagnosis in response to simulated presentations was 85%, with an accuracy of 88% in identifying the most-likely diagnosis after history-taking. H...
ChatGPT overestimated the urgency of indicated patient dispositions in 44% of cases, concerning for potential unnecessary increase in healthcare resource utilization. Imperfect performance, and the to...
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Inst...
This study aimed to develop a natural language processing algorithm (NLP) using machine learning (ML) and Deep Learning (DL) techniques to identify and classify documentation of suicidal behaviors in ...
Ground-glass opacities (GGOs) appearing in computed tomography (CT) scans may indicate potential lung malignancy. Proper management of GGOs based on their features can prevent the development of lung ...
We aimed to develop, test, and validate a deep learning-based natural language processing (NLP) tool that automatically extracts GGO features to inform the longitudinal trajectory of GGO status from l...
We developed a bidirectional long short-term memory with a conditional random field-based deep-learning NLP pipeline to extract GGO and granular features of GGO retrospectively from radiology notes of...
Our NLP pipeline built on the GGO ontology we developed achieved between 95% and 100% precision, 89% and 100% recall, and 92% and 100% F...
Our deep learning-based NLP pipeline can automatically extract granular GGO features at scale from electronic health records when this information is documented in radiology notes and help inform the ...
Automated and data-driven methods for screening using natural language processing (NLP) and machine learning may replace resource-intensive manual approaches in the usual care of patients hospitalized...
This study aims to provide a study protocol to evaluate health outcomes and the costs and benefits of an AI-driven automated screener compared to manual human screening for unhealthy substance use....
A pre-post design is proposed to evaluate 12 months of manual screening followed by 12 months of automated screening across surgical and medical wards at a single medical center. The preintervention p...
The study will begin in September 2022. Monthly data monitoring and Data Safety Monitoring Board reporting are scheduled every 6 months throughout the study period. We anticipate reporting final resul...
The use of augmented intelligence for clinical decision support is growing with an increasing number of AI tools. We provide a research protocol for prospective evaluation of an automated NLP system f...
ClinicalTrials.gov NCT03833804; https://clinicaltrials.gov/ct2/show/NCT03833804....
DERR1-10.2196/42971....
Maternal cytomegalovirus (CMV) infection in pregnancy may result in vertical transmission of CMV to the child. Long-term effects of congenital CMV infection include visual, cognitive as well as neurol...
The Norwegian Mother, Father and Child Cohort Study (MoBa) is a prospective population-based pregnancy cohort that includes 95 200 mothers and 114 500 children. Blood samples were obtained from mother...
Among mothers of cases, 63.2% were CMV-IgG positive in the sample at birth, as compared to 55.9% among controls; OR 1.36, (95% CI; 1.05 to 1.76). Also, among case mothers, 8/118 (6.8%) initially seron...
This study shows a higher risk of delayed language development at three years of age in children born by mothers seropositive for CMV, compared to children born from seronegative mothers....
Young children from low-SES backgrounds are at higher risk for delayed language development, likely due to differences in their home language environment and decreased opportunities for back and forth...
To accelerate the use of outcome measures in rheumatology, we developed and evaluated a natural language processing (NLP) pipeline for extracting these measures from free-text outpatient rheumatology ...
We included all patients in RISE (2015-2018). The NLP pipeline extracted scores corresponding to 8 measures of rheumatoid arthritis (RA) disease activity (DA) and functional status (FS) documented in ...
We processed over 34 million notes from 854,628 patients, 158 practices, and 24 electronic health record (EHR) systems from RISE. Manual chart review revealed a sensitivity, positive predictive value ...
We developed an NLP pipeline to extract RA outcome measures from a national registry of notes from multiple EHR systems and found it to have good internal and external validity. This pipeline can faci...
Prenatal and infant daily exposures to pyrethroid pesticides (PYRs), used in the elimination of harmful organisms in the family environment and agricultural activities, may have an impact on children'...
To determine the impacts of prenatal and infant PYRs exposure on 2-year-old toddlers' language development....
From January 2016 to December 2018, women in the third trimester of pregnancy, in Yunnan rural area, China, were recruited, and the development of their newborns was observed from birth till the age o...
The median concentrations of 3PBA, 4F3PBA and DBCA creatinine-adjusted were 0.21, 0.19, and 0.15 μg/g in pregnancy, and 0.25, 0.72, and <LOD μg/g in infancy, respectively. The average scores of Langua...
Women in the third trimester of pregnancy and their infants were widely exposed to low-dose PYRs. Infant daily exposure to PYRs may negatively impact toddlers' language development, with the 6-8 month...
Simulation plays an important role as an alternative method for training of students, particularly in health education. As a result of coronavirus disease 2019 (COVID-19) restrictions of face-to-face ...
The scoping review aimed to determine what has been documented about simulation as a mode of clinical training in healthcare professions (HCPs) in order to guide speech-language pathology and audiolog...
A scoping review was conducted. Electronic bibliographic databases including Science Direct, PubMed, Scopus MEDLINE, ProQuest, Google Scholar and WorldCat were searched to identify peer reviewed publi...
A total of 32 articles met the inclusion criteria for this scoping review. Three themes emerged when reviewing the studies: (1) face-to-face simulations as a mode of clinical training, (2) virtual rea...
Current findings highlight the role and value of simulation as a clinical training mode during COVID-19 and beyond. However, there are aspects that need to be considered to ensure that this mode of cl...
Developmental Language Disorder (DLD) remains prevalent for secondary school students and continues to compromise educational, social and vocational outcomes within and beyond school. Community-based ...
Twenty-one educators were interviewed across three schools to understand their perceptions and experiences of the project and their view(s) of what assisted or compromised early implementation. Data w...
Educators reported gaining increased knowledge and awareness of DLD, which supported a reframing of their perceptions of student behaviour and learning issues. They identified the project provided the...
Overall, the educators found the project and implementation of strategies doable, acceptable, important, and sustainable. We explore the features of project design that appeared to contribute to educa...
