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"description": "Comment diagnostiquer une déficience en 16-alpha-hydroxylase ?\nQuels tests génétiques sont utilisés pour cette enzyme ?\nQuels symptômes peuvent indiquer un problème avec cette enzyme ?\nQuel rôle joue l'imagerie dans le diagnostic ?\nLes tests de fonction hépatique sont-ils pertinents ?",
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"description": "Quels traitements sont disponibles pour les déséquilibres hormonaux ?\nLes médicaments peuvent-ils aider à réguler cette enzyme ?\nY a-t-il des traitements non médicamenteux ?\nComment la chirurgie peut-elle être impliquée ?\nLes traitements sont-ils différents pour les hommes et les femmes ?",
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"description": "Quelles complications peuvent survenir avec un déséquilibre hormonal ?\nLes troubles psychologiques sont-ils liés à cette enzyme ?\nY a-t-il des risques de cancer associés ?\nComment les maladies métaboliques sont-elles liées ?\nLes complications sont-elles réversibles ?",
"url": "https://questionsmedicales.fr/mesh/D039181?mesh_terms=Interrupted+Time+Series+Analysis&page=4#section-complications"
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"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Steroid 16-alpha-hydroxylase",
"description": "Quels facteurs de risque sont associés à des troubles hormonaux ?\nL'âge influence-t-il le risque de déséquilibre hormonal ?\nLes médicaments peuvent-ils affecter cette enzyme ?\nLe mode de vie joue-t-il un rôle dans le risque ?\nLes facteurs environnementaux influencent-ils le risque ?",
"url": "https://questionsmedicales.fr/mesh/D039181?mesh_terms=Interrupted+Time+Series+Analysis&page=4#section-facteurs de risque"
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"@type": "Question",
"name": "Comment diagnostiquer une déficience en 16-alpha-hydroxylase ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins pour mesurer les niveaux d'hormones stéroïdiennes sont effectués."
}
},
{
"@type": "Question",
"name": "Quels tests génétiques sont utilisés pour cette enzyme ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des analyses génétiques ciblent les mutations dans le gène CYP3A4."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent indiquer un problème avec cette enzyme ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme l'hyperandrogénie ou des irrégularités menstruelles peuvent survenir."
}
},
{
"@type": "Question",
"name": "Quel rôle joue l'imagerie dans le diagnostic ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'imagerie peut aider à évaluer les glandes endocrines, mais n'est pas spécifique."
}
},
{
"@type": "Question",
"name": "Les tests de fonction hépatique sont-ils pertinents ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, car le foie est crucial pour le métabolisme des stéroïdes et peut indiquer des anomalies."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une surproduction d'androgènes ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Acné, hirsutisme, irrégularités menstruelles et infertilité peuvent se manifester."
}
},
{
"@type": "Question",
"name": "Comment se manifeste une insuffisance en stéroïdes ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fatigue, perte de poids, hypotension et dépression peuvent être des signes d'insuffisance."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon le sexe ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les hommes et les femmes peuvent présenter des symptômes différents en raison des hormones."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes associés à des troubles métaboliques ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles comme le diabète peuvent être liés à des anomalies hormonales."
}
},
{
"@type": "Question",
"name": "Les symptômes peuvent-ils apparaître à l'adolescence ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des changements hormonaux peuvent se manifester durant la puberté."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les troubles liés à cette enzyme ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une surveillance régulière et un mode de vie sain peuvent aider à prévenir certains troubles."
}
},
{
"@type": "Question",
"name": "Y a-t-il des tests de dépistage recommandés ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests hormonaux réguliers peuvent être recommandés pour les personnes à risque."
}
},
{
"@type": "Question",
"name": "Comment l'éducation peut-elle aider à la prévention ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'éducation sur les symptômes et les risques peut aider à une détection précoce."
}
},
{
"@type": "Question",
"name": "Les habitudes alimentaires influencent-elles la santé hormonale ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation équilibrée peut soutenir la santé hormonale et prévenir des déséquilibres."
}
},
{
"@type": "Question",
"name": "Le stress a-t-il un impact sur cette enzyme ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut affecter la production hormonale et aggraver les symptômes."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour les déséquilibres hormonaux ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies hormonales substitutives peuvent être prescrites pour rétablir l'équilibre."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils aider à réguler cette enzyme ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains inhibiteurs enzymatiques peuvent être utilisés pour moduler l'activité."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements non médicamenteux ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des changements de mode de vie, comme l'alimentation et l'exercice, peuvent aider."
}
},
{
"@type": "Question",
"name": "Comment la chirurgie peut-elle être impliquée ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Dans certains cas, une intervention chirurgicale peut être nécessaire pour corriger des anomalies."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils différents pour les hommes et les femmes ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent être adaptés en fonction des besoins hormonaux spécifiques."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec un déséquilibre hormonal ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme l'infertilité, le diabète et des maladies cardiovasculaires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Les troubles psychologiques sont-ils liés à cette enzyme ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles comme l'anxiété et la dépression peuvent être exacerbés par des déséquilibres."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de cancer associés ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent un lien entre les déséquilibres hormonaux et le cancer hormonal."
}
},
{
"@type": "Question",
"name": "Comment les maladies métaboliques sont-elles liées ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les déséquilibres hormonaux peuvent contribuer à des maladies métaboliques comme le diabète."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être réversibles avec un traitement approprié et précoce."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque sont associés à des troubles hormonaux ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des antécédents familiaux, l'obésité et le stress sont des facteurs de risque connus."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque de déséquilibre hormonal ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque augmente avec l'âge, surtout pendant la ménopause chez les femmes."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils affecter cette enzyme ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments peuvent interférer avec l'activité de la stéroïde 16-alpha-hydroxylase."
}
},
{
"@type": "Question",
"name": "Le mode de vie joue-t-il un rôle dans le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation augmentent le risque."
}
},
{
"@type": "Question",
"name": "Les facteurs environnementaux influencent-ils le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certains produits chimiques peut affecter la fonction hormonale."
}
}
]
}
]
}
To analyze the impact of the fiscal austerity policy (PAF) on health spending in Brazilian municipalities, considering population size and source of funds....
The interrupted time series method was used to analyze the effect of the PAF on total expenditure, resources transferred by the Federal Government, and own/state per capita resources allocated to heal...
The results for the national average of municipalities show that the PAF had a negative impact on the level of total expenditure and own/state resources allocated to health in the first half of 2015, ...
In general, the impact of the PAF on health financing in municipalities was immediate and based on the decrease in own/state resources allocated to health. In large municipalities, however, the impact...
Although the transfer of patients between acute care hospitals (interhospital transfer, IHT) is common, health information exchange (HIE) during IHT remains inadequate, with fragmented communication a...
Study subjects include patients aged >18 transferred to the medical, cardiology, oncology, or intensive care unit (ICU) services at an 800-bed quaternary care hospital; and healthcare workers involved...
We will track patient safety endpoints and clinician workflow burdens and ensure the protection of patient data throughout the study. We will disseminate our findings via the creation of a toolkit for...
Fixed and broad screening intervals for drug-drug interaction (DDI) alerts lead to false positive alerts, thereby contributing to alert fatigue among healthcare professionals. Hence, we aimed to inves...
Pregnancy and childbirth complications are the leading cause of death among girls aged 15-19 years globally, with low- and middle-income countries (LMICs) accounting for 99% of global maternal deaths ...
Using interrupted time series analysis (ITS), sometimes known as quasi-experimental time series analysis. We constructed a time series of the first ANC service utilization records for girls aged 10-19...
The teenage pregnancy trend before the lockdown was decreasing by - 0.203 pregnancies per month, but in the first month after the institution of the lockdown (March 20, 2020), there was an increase in...
Teenage pregnancies increased during the lockdown. This slight increase depicted the impact of the pandemic on the teenage pregnancy trend associated with the COVID-19 outbreak. The government needs t...
Bans on evictions were implemented to reduce the spread of COVID-19 and to protect vulnerable populations during a public health crisis. Our objective was to examine how three bans on eviction enforce...
Data were derived from eviction application records kept by the Ontario Landlord and Tenant Board. We used segmented regression analysis to model changes in the average weekly filing rates for evictio...
The average number of weekly L1 and L2 applications dropped by 67.5 (95% CI: 55.2, 79.9) and 31.7 (95% CI: 26.7, 36.6) filings per 100,000 rental dwellings, respectively, following the first ban on ev...
Our findings suggest that while the first ban on eviction enforcement appeared to substantially reduce filing rates, subsequent bans were less effective and none of them eliminated eviction filings al...
Epidemics are anticipated to influence the coverage of health services. We assessed the impact of the COVID-19 pandemic on maternal healthcare indices and care providers' performance....
1801 maternal healthcare centres under the auspices of Shiraz University of Medical Sciences, Shiraz, Southern Iran....
Approximately 63 000 pregnant women....
In this prospective ecological study, interrupted time series analysis was used to model and compare the trend of maternal healthcare indices before and after the COVID-19 pandemic announcement....
The results showed a significant drop in count of preconception healthcare visits, first routine laboratory tests, first trimester prenatal care, first trimester sonography, prenatal screening for bir...
Using ecological data during the COVID-19 pandemic era, we observed a 'level change and slope change' as the major pattern of interruption of maternal healthcare coverage, indicating a possible indire...
In 2016, China initiated the merge of the urban resident basic medical insurance scheme and new rural cooperative medical scheme into one unified health insurance scheme: the urban and rural resident ...
Data published early in the COVID-19 pandemic suggested that smokers infected with SARS-CoV-2 were more likely to need hospital treatment or die than non-smokers, and thus this was seen as a motivator...
Interrupted time series analysis to investigate the impact of COVID-19, and the shift to remote delivery of smoking cessation support, on the number of smokers who accessed cessation support with LLBD...
11,393 episodes of smoking cessation support were opened with LLBD between 01 January 2018 and 31 December 2021. The weekly count of all outcomes was increasing prior to the date when LLBD converted t...
The COVID-19 pandemic, and associated shift to remote delivery of smoking cessation support by LLBD, had no substantial sustained overall impact on measures of smoking cessation service activity and s...
Preliminary evidence from China and other countries has suggested that coronavirus disease 2019 (COVID-19) mitigation measures have caused a decline in preterm births, but evidence is conflicting. Uti...
To prevent tobacco use in Korea, the national quitline number was added to tobacco packages in December 2012, tobacco prices were raised by 80% in January 2015, and graphic health warning labels were ...
Monthly mortality from suicide was obtained from Cause-of-Death Statistics in Korea from December 2007 to December 2019. Interrupted time-series analysis was performed using segmented Poisson regressi...
Suicide mortality was 20 per 1,000,000 in December 2007 and showed a downward trend over the study period. After the implementation of tobacco packaging and pricing policies, suicide mortality immedia...
The findings of this study provide new evidence for an association between tobacco control policies and deaths by suicide. An array of effective tobacco control policies should be considered for preve...