Chromosomes X humains : Questions médicales fréquentes
Nom anglais: Chromosomes, Human, X
Descriptor UI:D041321
Tree Number:G05.360.162.865.982.500
Termes MeSH sélectionnés :
Cognition
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"description": "Comment diagnostiquer une anomalie du chromosome X ?\nQuels tests génétiques sont utilisés pour le chromosome X ?\nQuels symptômes indiquent une anomalie du chromosome X ?\nLes échographies peuvent-elles détecter des anomalies chromosomiques ?\nQuel rôle joue le conseil génétique dans le diagnostic ?",
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"description": "Quels sont les symptômes du syndrome de Turner ?\nComment se manifeste le syndrome de Klinefelter ?\nQuels symptômes sont associés à l'X fragile ?\nLes anomalies du chromosome X affectent-elles le développement physique ?\nY a-t-il des symptômes psychologiques liés aux anomalies du chromosome X ?",
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"description": "Peut-on prévenir les anomalies du chromosome X ?\nQuel rôle joue la nutrition dans la prévention ?\nLes vaccinations peuvent-elles prévenir des anomalies ?\nComment le suivi médical aide-t-il à prévenir les anomalies ?\nLe dépistage prénatal est-il recommandé ?",
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"description": "Quelles complications peuvent survenir avec le syndrome de Turner ?\nLe syndrome de Klinefelter entraîne-t-il des complications ?\nQuelles sont les complications de l'X fragile ?\nLes anomalies du chromosome X affectent-elles la longévité ?\nY a-t-il des complications liées à la grossesse avec ces anomalies ?",
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"description": "Quels facteurs augmentent le risque d'anomalies chromosomiques ?\nLes facteurs environnementaux influencent-ils les anomalies ?\nLe tabagisme est-il un facteur de risque ?\nLes maladies génétiques familiales augmentent-elles le risque ?\nL'alimentation joue-t-elle un rôle dans le risque d'anomalies ?",
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"@type": "Question",
"name": "Comment diagnostiquer une anomalie du chromosome X ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un caryotype ou un test génétique peut révéler des anomalies du chromosome X."
}
},
{
"@type": "Question",
"name": "Quels tests génétiques sont utilisés pour le chromosome X ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests de séquençage et les analyses de microdélétions sont courants."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une anomalie du chromosome X ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes peuvent inclure des troubles du développement et des problèmes de fertilité."
}
},
{
"@type": "Question",
"name": "Les échographies peuvent-elles détecter des anomalies chromosomiques ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines anomalies peuvent être suspectées lors des échographies prénatales."
}
},
{
"@type": "Question",
"name": "Quel rôle joue le conseil génétique dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le conseil génétique aide à évaluer le risque et à interpréter les résultats des tests."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes du syndrome de Turner ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent un retard de croissance, des anomalies cardiaques et des problèmes hormonaux."
}
},
{
"@type": "Question",
"name": "Comment se manifeste le syndrome de Klinefelter ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il se manifeste par une gynécomastie, une infertilité et des troubles d'apprentissage."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont associés à l'X fragile ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des retards mentaux, des troubles du comportement et des caractéristiques physiques spécifiques."
}
},
{
"@type": "Question",
"name": "Les anomalies du chromosome X affectent-elles le développement physique ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent entraîner des malformations congénitales et des retards de développement."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes psychologiques liés aux anomalies du chromosome X ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles de l'humeur et des problèmes d'anxiété peuvent survenir."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les anomalies du chromosome X ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines anomalies peuvent être évitées par le dépistage génétique et le conseil prénatal."
}
},
{
"@type": "Question",
"name": "Quel rôle joue la nutrition dans la prévention ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une bonne nutrition maternelle peut réduire le risque de complications chromosomiques."
}
},
{
"@type": "Question",
"name": "Les vaccinations peuvent-elles prévenir des anomalies ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections évitables par vaccination peuvent réduire les risques de malformations."
}
},
{
"@type": "Question",
"name": "Comment le suivi médical aide-t-il à prévenir les anomalies ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi médical régulier permet de détecter précocement des problèmes potentiels."
}
},
{
"@type": "Question",
"name": "Le dépistage prénatal est-il recommandé ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage prénatal est recommandé pour évaluer les risques d'anomalies chromosomiques."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour le syndrome de Turner ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des thérapies hormonales et un suivi médical régulier."
}
},
{
"@type": "Question",
"name": "Comment traiter le syndrome de Klinefelter ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement peut inclure des thérapies hormonales et des interventions pour l'infertilité."
}
},
{
"@type": "Question",
"name": "Y a-t-il un traitement pour l'X fragile ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de traitement curatif, mais des thérapies éducatives et comportementales aident."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils différents selon le sexe ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent varier en fonction des symptômes et des besoins spécifiques."
}
},
{
"@type": "Question",
"name": "Comment la physiothérapie aide-t-elle les patients ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "La physiothérapie peut améliorer la mobilité et la force musculaire chez les patients affectés."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec le syndrome de Turner ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des problèmes cardiaques, rénaux et des troubles de la fertilité."
}
},
{
"@type": "Question",
"name": "Le syndrome de Klinefelter entraîne-t-il des complications ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il peut entraîner des complications endocriniennes et des problèmes de santé mentale."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications de l'X fragile ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles d'apprentissage et des problèmes comportementaux."
}
},
{
"@type": "Question",
"name": "Les anomalies du chromosome X affectent-elles la longévité ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines anomalies peuvent réduire l'espérance de vie en raison de complications associées."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications liées à la grossesse avec ces anomalies ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les femmes avec des anomalies chromosomiques peuvent avoir des grossesses à risque."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque d'anomalies chromosomiques ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'âge maternel avancé et des antécédents familiaux augmentent le risque."
}
},
{
"@type": "Question",
"name": "Les facteurs environnementaux influencent-ils les anomalies ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certaines substances chimiques peut augmenter le risque d'anomalies."
}
},
{
"@type": "Question",
"name": "Le tabagisme est-il un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme pendant la grossesse est associé à un risque accru d'anomalies chromosomiques."
}
},
{
"@type": "Question",
"name": "Les maladies génétiques familiales augmentent-elles le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents de maladies génétiques dans la famille peuvent accroître le risque."
}
},
{
"@type": "Question",
"name": "L'alimentation joue-t-elle un rôle dans le risque d'anomalies ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation déséquilibrée peut contribuer à des risques accrus d'anomalies chromosomiques."
}
}
]
}
]
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To explore the interrelationships between oral hygiene habits, oral health status and cognitive function in older adults....
A cross-sectional study....
A total of 371 participants (age 76.79 [7.99] years) were enrolled from June 2020 to November 2021 in an aged care facility....
Cognitive function was screened using the mini-mental state examination (MMSE) with adjusted cut-off points for age and education. Periodontal status (Biofilm-Gingival Interface index based on periodo...
Poor periodontal status was an associated factor for MCI (OR = 2.89, 95% CI = 1.20-6.95), while multiple tooth loss (OR = 4.90, 95% CI = 1.06 ~ 22.59), brushing teeth less than once a day (OR = 2.88, ...
Adequate toothbrushing might prevent cognitive decline indirectly by improving periodontal health only in older adults without cognitive impairment. Multiple tooth loss, infrequent toothbrushing, and ...
The information on oral health habits of this study was based on an interview with the participants or their caregivers during the study period....
Dual-task training may be relevant and efficient in the context of active aging. An issue in training programs lies in enhancing the adherence of participants. This can potentially be improved using g...
Older adults aged 65 years or older were recruited and realized 30 min of supervised training in groups of 4, 2-3 times a week for 12 weeks. Exercises consisted of incorporated cognitive and motor dua...
Thirty-nine participants (aged 84.6 ± 8.5 years) were recruited. No adverse events, and 89% adherence, 88% attendance, and 87% completion rates were observed. A potentially significant effect of our e...
Our exergame seemed feasible and safe and was enjoyed by participants, mainly due to the gamification of our training program. Moreover, our exergame may be efficient for cognitive training in older a...
The aim of the study is to observe the effects of cognitive behavioral therapy on stress disorder, cognitive function, motor function, and daily living ability of traumatic brain injury (TBI) patients...
84 patients with TBI admitted to our hospital from June 2019 to May 2021 were selected as the research subjects. They were divided into a control group (from June 2019 to May 2020) and an observation ...
After intervention, the PTSD-self-rating scale (PTSD-SS) scores of both groups were lower than those before intervention, and the PTSD-SS scores of the observation group were lower than those of the c...
The application of cognitive behavioral therapy to TBI patients is beneficial to reduce the degree of PTSD and improve cognitive function, motor function, and daily living ability, which is worthy of ...
In 2021, the US Food and Drug Administration granted an accelerated approval to aducanumab for patients with mild cognitive impairment (MCI) and mild dementia caused by Alzheimer's disease (AD); howev...
PubMed, the Cochrane Library, CINHAL, and ClinicalTrials.gov were searched for randomized controlled trials testing lithium or aducanumab for the treatment of cognitive decline in patients with MCI or...
Network meta-analysis demonstrated that lithium was significantly more effective than aducanumab in the primary outcome....
Although there were various limitations in this study, lithium may be a more cost-effective treatment than aducanumab for MCI and AD....
Whole genome methylation sequencing (WGMS) in blood identifies differential DNA methylation in persons with late-onset dementia due to Alzheimer's disease (AD) but has not been tested in persons with ...
We used WGMS to compare DNA methylation levels at 25,244,219 CpG loci in 382 blood samples from 99 persons with MCI, 109 with AD, and 174 who are cognitively unimpaired (CU)....
WGMS identified 9,756 differentially methylated positions (DMPs) in persons with MCI, including 1,743 differentially methylated genes encoding proteins in biological pathways related to synapse organi...
WGMS identifies DMPs in known and newly detected genes in blood from persons with MCI and AD that support blood DNA methylation levels as candidate biomarkers of cognitive status....
The Cognitive Failures Questionnaire (CFQ) has been widely used as a measure of subjective cognitive function in everyday life for decades. However, the evidence on how it relates to objective perform...
Olfactory dysfunction is an early sign of such neurodegenerative diseases as Parkinson's (PD) and Alzheimer's (AD), and is often present in Mild Cognitive Impairment (MCI), a precursor of AD. Understa...
This study aimed to explore the associations between brain structures, cognition, and motor control in participants with mild cognitive impairment (MCI), with a focus on dual-task performance....
Thirty MCI patients and thirty healthy controls were enrolled. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA). Structural magnetic resonance imaging data were analyzed ...
MCI patients showed significantly lower MoCA scores, particularly in visuospatial/executive, attention, and delayed recall domains (p < 0.05). Dual-task TUG execution time was significantly increased ...
Smaller GMV in the right anterior lobe of the cerebellum was associated with impaired dual-task performance, which may provide more evidence for the neural mechanisms of cognitive and motor function i...
This study investigated the impact of language learning in comparison to other complex learning activities on cognitive functioning and psychosocial well-being in cognitively healthy, community-dwelli...
Computerized cognitive training (CCT) has been proposed as a potential therapy for cognitive decline. One of the benefits of CCT is a transfer effect, but its mechanism on the memory domain is unclear...
Patients with MCI recruited from memory clinics were randomly assigned to either the CCT or the control group. The CCT group received multidomain CCT training excluding memory training, while the cont...
The CCT group showed improvement over the control group in memory domain (Group × time, F = 5.87, P = 0.03, η...
Eight weeks of multidomain CCT without memory training improved memory function and restored functional network in the hippocampal and medial temporal region in MCI patients. These results can provide...