Comment diagnostiquer une dysfonction endothéliale ?

Des tests comme l'échographie Doppler et les marqueurs sanguins peuvent être utilisés.

Quels examens pour évaluer les cellules endothéliales ?

Les biopsies tissulaires et les analyses histologiques sont couramment pratiquées.

Quels marqueurs biologiques indiquent une inflammation endothéliale ?

Des marqueurs comme la protéine C-réactive et les cytokines peuvent être mesurés.

Comment évaluer la perméabilité endothéliale ?

Des tests de perméabilité utilisant des colorants ou des marqueurs radioactifs sont effectués.

Quels tests pour détecter des lésions endothéliales ?

L'angiographie et l'imagerie par résonance magnétique peuvent révéler des lésions.

Quels symptômes indiquent une dysfonction endothéliale ?

Des douleurs thoraciques, des troubles circulatoires et des œdèmes peuvent survenir.

Comment reconnaître une inflammation endothéliale ?

Rougeur, chaleur et gonflement au site affecté sont des signes d'inflammation.

Quels signes cliniques d'athérosclérose ?

Douleurs dans la poitrine, fatigue et essoufflement peuvent indiquer une athérosclérose.

Quels symptômes d'une thrombose veineuse ?

Gonflement, douleur et rougeur dans la zone touchée sont des symptômes courants.

Comment se manifeste une ischémie ?

L'ischémie se manifeste par des douleurs, des engourdissements et une faiblesse musculaire.

Comment prévenir la dysfonction endothéliale ?

Un mode de vie sain, incluant une alimentation équilibrée et de l'exercice, est essentiel.

Quelles habitudes pour réduire l'inflammation ?

Éviter le tabac, réduire le stress et consommer des aliments anti-inflammatoires aide.

Comment prévenir l'athérosclérose ?

Contrôler la pression artérielle, le cholestérol et pratiquer une activité physique régulière.

Quelles mesures pour éviter la thrombose ?

Rester actif, s'hydrater et éviter de rester immobile longtemps sont des mesures préventives.

Comment réduire le risque d'ischémie ?

Gérer le diabète, contrôler le poids et éviter les aliments riches en graisses saturées.

Quels traitements pour la dysfonction endothéliale ?

Des médicaments comme les statines et des changements de mode de vie sont recommandés.

Comment traiter l'inflammation endothéliale ?

Des anti-inflammatoires et des corticostéroïdes peuvent être prescrits selon la gravité.

Quelles interventions pour l'athérosclérose ?

Des procédures comme l'angioplastie ou le pontage peuvent être nécessaires.

Quels médicaments pour prévenir la thrombose ?

Les anticoagulants et les antiplaquettaires sont souvent utilisés pour prévenir la thrombose.

Comment gérer l'ischémie chronique ?

Des traitements médicaux, des exercices et parfois une chirurgie sont envisagés.

Quelles complications de la dysfonction endothéliale ?

Elle peut entraîner des maladies cardiovasculaires, des AVC et des troubles circulatoires.

Quels risques liés à l'inflammation endothéliale ?

L'inflammation peut provoquer des thromboses, des embolies et des maladies auto-immunes.

Quelles complications de l'athérosclérose ?

Elle peut mener à des crises cardiaques, des AVC et des douleurs angineuses.

Quels dangers d'une thrombose veineuse ?

Une thrombose peut provoquer une embolie pulmonaire, mettant en danger la vie.

Quelles complications de l'ischémie ?

L'ischémie peut entraîner des lésions tissulaires, des gangrènes et des amputations.

Quels facteurs de risque pour la dysfonction endothéliale ?

L'hypertension, le diabète, le tabagisme et l'obésité augmentent le risque.

Comment le stress influence-t-il l'endothélium ?

Le stress chronique peut aggraver l'inflammation et la dysfonction endothéliale.

Quels rôles du cholestérol dans la santé endothéliale ?

Un taux élevé de cholestérol LDL est un facteur de risque majeur pour les maladies vasculaires.

Comment l'alimentation affecte-t-elle l'endothélium ?

Une alimentation riche en graisses saturées et en sucres peut nuire à la fonction endothéliale.

Quels impacts de l'inactivité physique sur l'endothélium ?

Le manque d'exercice physique contribue à la dysfonction endothéliale et aux maladies cardiovasculaires.

Cellules endothéliales - Informations médicales vérifiées

Method evaluation in the clinical laboratory.

25 04 2023

DOI: 10.1515/cclm-2022-0878 PMID: 36327459

Method evaluation is one of the critical components of the quality system that ensures the ongoing quality of a clinical laboratory. As part of implementing new methods or reviewing best practices, th...

Humans Laboratories, Clinical Clinical Laboratory Services Clinical Laboratory Techniques Laboratories

The publication quality of laboratory values in clinical studies in neonates.

07 2023

DOI: 10.1038/s41390-022-02385-1 PMID: 36550353

There are no generally accepted age-appropriate reference ranges for laboratory values in neonates. This also matters for drug development. The International Neonatal Consortium (INC) is engaged to de... A structured literature search was performed to identify standards or recommendations for publications that present neonatal laboratory data to assess the publication quality of laboratory values in n... On 2908 hits, 281 papers were retained for full reading and 257 for data extraction. None of the papers reported a publication standard. Using the extraction instrument, most papers presented single c... Published information on laboratory values for neonates is sparse, not systematic, and incomplete. This undermines efforts to compare treatments, safety monitoring, or clinical management. Furthermore... There are no generally accepted age-appropriate reference ranges for laboratory values in neonates, leading to a significant knowledge gap, also for safety reporting and drug development in neonates. ...

Humans Infant, Newborn Bibliometrics Publications Reference Values +3 autres

A comprehensive review of COVID-19 detection techniques: From laboratory systems to wearable devices.

10 2022

DOI: 10.1016/j.compbiomed.2022.106070 PMID: 36099862

Screening of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among symptomatic and asymptomatic patients offers unique opportunities for curtailing the transmission of novel coronavirus d...

Artificial Intelligence COVID-19 COVID-19 Testing Clinical Laboratory Techniques Humans +3 autres

Compliance with the clinical laboratory quality protocol in public primary healthcare centres.

29 Jul 2022

DOI: 10.1097/MD.0000000000029095 PMID: 35905269

The clinical and economic relevance of the clinical laboratories procedures in Andalusia (Spain) have led the Regional Department of Health to focus attention on their improvement. A unified laborator...

Clinical Laboratory Techniques Cross-Sectional Studies Humans Laboratories Laboratories, Clinical +1 autres

Analysis of preanalytical errors in a clinical chemistry laboratory: A 2-year study.

08 Jul 2022

DOI: 10.1097/MD.0000000000029853 PMID: 35801773

Patient safety and medical diagnosis of patients are mainly influenced by laboratory results. The present study aimed to evaluate the errors in the preanalytical phase of testing in a Clinical Chemist...

Chemistry, Clinical Clinical Laboratory Services Clinical Laboratory Techniques Diagnostic Errors Hemolysis +2 autres

Clinical decision limits as criteria for setting analytical performance specifications for laboratory tests.

01 Feb 2023

DOI: 10.1016/j.cca.2023.117233 PMID: 36693582

The biological (CV... The sum of the CV... The obtained CAAPS were 44.9% for urine albumin, 0.6% for plasma sodium, 22.9% for plasma pancreatic amylase, and 8.0% for plasma creatinine (z = 3, α = 2.5%, 1-β = 85%). For blood HbA... The CAAPS models pose a new tool for assessing APS in a clinical laboratory. Their usability depends on the relevance of CD limits, required statistical power and the feasibility of repeated measureme...

Humans Clinical Laboratory Techniques Chemistry, Clinical

Interpreting changes in consecutive laboratory results: clinician's perspectives on clinically significant change.

01 Aug 2023

DOI: 10.1016/j.cca.2023.117462 PMID: 37390943

Clinical laboratory tests are inevitably affected by various factors. Therefore, when comparing consecutive test results, it is crucial to consider the inherent uncertainty of the test. Clinical labor... We performed a questionnaire survey on clinicians, which comprised 2 scenarios with 22 laboratory test items suggesting initial test results. Clinicians were asked to choose a result showing clinicall... We received 290 valid questionnaire responses. Clinicians' opinions on clinically significant change was inconsistent between clinicians and scenarios, and was generally larger than RCV. Clinicians co... Clinicians' opinions on clinically significant changes were more prominent than RCV. Meanwhile, they tended to neglect the analytical and biological variation. Laboratories should properly guide clini...

Humans Laboratories Clinical Laboratory Techniques Uncertainty Clinical Laboratory Services +1 autres

Incorporating informatively collected laboratory data from EHR in clinical prediction models.

24 Jul 2024

DOI: 10.1186/s12911-024-02612-1 PMID: 39049049

Electronic Health Records (EHR) are widely used to develop clinical prediction models (CPMs). However, one of the challenges is that there is often a degree of informative missing data. For example, l... We considered a predictive model for rapid inpatient deterioration as an exemplar implementation. This model incorporated twelve laboratory measures with varying levels of missingness. Five labs had m... We had 105,198 inpatient encounters, with 4.7% having experienced the deterioration outcome of interest. LSTM models generally outperformed other cross-sectional models, where embedding approaches and... Strategies that accounted for the possibility of NMAR missing data yielded better model performance than those did not. The embedding method had an advantage as it did not require prior clinical knowl...

Electronic Health Records Humans Clinical Deterioration Models, Statistical Clinical Laboratory Techniques

The Nature, Causes, and Clinical Impact of Errors in the Clinical Laboratory Testing Process Leading to Diagnostic Error: A Voluntary Incident Report Analysis.

01 Dec 2023

DOI: 10.1097/PTS.0000000000001166 PMID: 37796227

Diagnostic errors, that is, missed, delayed, or wrong diagnoses, are a common type of medical errors and preventable iatrogenic harm. Errors in the laboratory testing process can lead to diagnostic er... We used a sample of 600 voluntary incident reports concerning diagnostic testing selected from all incident reports filed at the University Medical Center Utrecht in 2017-2018. From these incident rep... Three hundred twenty-seven reports were included in the analysis. In 77.1%, the error occurred in the preanalytical phase, 13.5% in the analytical phase and 8.0% in the postanalytical phase (1.5% unde... Errors in the laboratory testing process often lead to potential diagnostic errors. Although prone to incomplete information on causes and clinical impact, voluntary incident reports are a valuable so...

Humans Retrospective Studies Risk Management Diagnostic Errors Clinical Laboratory Techniques +1 autres

The experience and reflections of GC labs as an independent clinical laboratory to the COVID-19 pandemic in South Korea.

06 Dec 2023

DOI: 10.1186/s12879-023-08684-0 PMID: 38057704

Amid the COVID-19 pandemic, extensive testing was undertaken by independent clinical laboratories (ICLs), yet limited research exists on this matter. Drawing from Green Cross Laboratories (GC Labs)' p... This retrospective study analyzed the outcomes of SARS-CoV-2 real-time reverse transcription polymerase chain reaction (SARS-CoV-2 rRT PCR) tests administered by GC Labs for COVID-19 diagnosis, upon r... ICLs were responsible for conducting 85.6% of all tests carried out under South Korea's COVID-19 testing policy during the pandemic. The availability of free testing regardless of symptoms led to a si... South Korea's ICLs were able to conduct large volumes of testing during the COVID-19 pandemic because of their logistics and computer systems, scalable testing space, and trained testing personnel. Th...

Humans COVID-19 COVID-19 Testing SARS-CoV-2 Laboratories, Clinical +4 autres

Cellules endothéliales : Questions médicales fréquentes

Termes MeSH sélectionnés :

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Progéniteurs endothéliaux

Cellules endothéliales de la veine ombilicale humaine

Podosomes

Auteurs principaux

Sources (10000 au total)