Titre : Facteurs de transcription EGR

Facteurs de transcription EGR : Questions médicales fréquentes

Termes MeSH sélectionnés :

Implementation Science
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compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-17", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Facteurs de transcription EGR", "description": "Comment diagnostiquer une dysrégulation des EGR ?\nQuels tests sont utilisés pour évaluer les EGR ?\nLes EGR peuvent-ils être mesurés dans le sang ?\nQuels symptômes indiquent une anomalie des EGR ?\nLes EGR sont-ils impliqués dans des maladies spécifiques ?", "url": "https://questionsmedicales.fr/mesh/D051765?mesh_terms=Implementation+Science&page=6#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Facteurs de transcription EGR", "description": "Quels symptômes sont liés à une surproduction d'EGR ?\nLes EGR affectent-ils le système immunitaire ?\nQuels signes cliniques sont associés aux EGR ?\nLes EGR sont-ils liés à des troubles mentaux ?\nComment les EGR influencent-ils le développement embryonnaire ?", "url": "https://questionsmedicales.fr/mesh/D051765?mesh_terms=Implementation+Science&page=6#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Facteurs de transcription EGR", "description": "Peut-on prévenir les anomalies liées aux EGR ?\nLes facteurs environnementaux influencent-ils les EGR ?\nComment réduire le risque de dysrégulation des EGR ?\nL'exercice physique influence-t-il les EGR ?\nLes suppléments nutritionnels affectent-ils les EGR ?", "url": "https://questionsmedicales.fr/mesh/D051765?mesh_terms=Implementation+Science&page=6#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Facteurs de transcription EGR", "description": "Existe-t-il des traitements ciblant les EGR ?\nComment moduler l'activité des EGR ?\nLes EGR peuvent-ils être une cible pour le cancer ?\nQuels médicaments affectent les EGR ?\nLes EGR sont-ils impliqués dans la thérapie cellulaire ?", "url": "https://questionsmedicales.fr/mesh/D051765?mesh_terms=Implementation+Science&page=6#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Facteurs de transcription EGR", "description": "Quelles complications peuvent survenir avec des EGR anormaux ?\nLes EGR sont-ils liés à des maladies chroniques ?\nComment les EGR affectent-ils la santé cardiovasculaire ?\nLes EGR peuvent-ils causer des troubles neurologiques ?\nQuelles sont les conséquences d'une surproduction d'EGR ?", "url": "https://questionsmedicales.fr/mesh/D051765?mesh_terms=Implementation+Science&page=6#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Facteurs de transcription EGR", "description": "Quels facteurs augmentent le risque de dysrégulation des EGR ?\nLe stress influence-t-il les EGR ?\nL'alimentation joue-t-elle un rôle dans les EGR ?\nLes infections affectent-elles les EGR ?\nL'âge est-il un facteur de risque pour les EGR ?", "url": "https://questionsmedicales.fr/mesh/D051765?mesh_terms=Implementation+Science&page=6#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une dysrégulation des EGR ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests génétiques et des analyses d'expression génique peuvent être utilisés." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour évaluer les EGR ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests PCR et les Western blot sont couramment utilisés pour évaluer l'expression des EGR." } }, { "@type": "Question", "name": "Les EGR peuvent-ils être mesurés dans le sang ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Actuellement, il n'existe pas de tests sanguins standardisés pour mesurer les EGR." } }, { "@type": "Question", "name": "Quels symptômes indiquent une anomalie des EGR ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des anomalies de croissance ou des troubles neurologiques peuvent indiquer une dysrégulation." } }, { "@type": "Question", "name": "Les EGR sont-ils impliqués dans des maladies spécifiques ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils sont associés à des maladies comme le cancer et les troubles neurodégénératifs." } }, { "@type": "Question", "name": "Quels symptômes sont liés à une surproduction d'EGR ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Une surproduction peut entraîner une hyperplasie cellulaire et des troubles de croissance." } }, { "@type": "Question", "name": "Les EGR affectent-ils le système immunitaire ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils régulent la réponse immunitaire et peuvent influencer l'inflammation." } }, { "@type": "Question", "name": "Quels signes cliniques sont associés aux EGR ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Des signes comme la fatigue, des douleurs musculaires et des troubles cognitifs peuvent apparaître." } }, { "@type": "Question", "name": "Les EGR sont-ils liés à des troubles mentaux ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Des études montrent un lien potentiel entre les EGR et des troubles comme la dépression." } }, { "@type": "Question", "name": "Comment les EGR influencent-ils le développement embryonnaire ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Ils jouent un rôle crucial dans la régulation des gènes nécessaires au développement embryonnaire." } }, { "@type": "Question", "name": "Peut-on prévenir les anomalies liées aux EGR ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir certaines anomalies." } }, { "@type": "Question", "name": "Les facteurs environnementaux influencent-ils les EGR ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des facteurs comme le stress et la pollution peuvent affecter leur expression." } }, { "@type": "Question", "name": "Comment réduire le risque de dysrégulation des EGR ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Éviter les toxines et maintenir un bon équilibre hormonal peut réduire le risque." } }, { "@type": "Question", "name": "L'exercice physique influence-t-il les EGR ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exercice régulier peut moduler l'expression des EGR et améliorer la santé globale." } }, { "@type": "Question", "name": "Les suppléments nutritionnels affectent-ils les EGR ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Certains suppléments, comme les acides gras oméga-3, peuvent influencer leur expression." } }, { "@type": "Question", "name": "Existe-t-il des traitements ciblant les EGR ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Des thérapies géniques et des inhibiteurs spécifiques sont en cours de recherche." } }, { "@type": "Question", "name": "Comment moduler l'activité des EGR ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Des agents pharmacologiques et des modifications épigénétiques peuvent moduler leur activité." } }, { "@type": "Question", "name": "Les EGR peuvent-ils être une cible pour le cancer ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les EGR sont des cibles potentielles pour des traitements anticancéreux innovants." } }, { "@type": "Question", "name": "Quels médicaments affectent les EGR ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Certains médicaments anti-inflammatoires peuvent influencer l'expression des EGR." } }, { "@type": "Question", "name": "Les EGR sont-ils impliqués dans la thérapie cellulaire ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, leur régulation est essentielle pour le succès des thérapies cellulaires et régénératives." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec des EGR anormaux ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications comme le cancer, les maladies auto-immunes et les troubles métaboliques peuvent survenir." } }, { "@type": "Question", "name": "Les EGR sont-ils liés à des maladies chroniques ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une dysrégulation des EGR est associée à des maladies chroniques comme le diabète." } }, { "@type": "Question", "name": "Comment les EGR affectent-ils la santé cardiovasculaire ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Une régulation anormale des EGR peut contribuer à des maladies cardiovasculaires." } }, { "@type": "Question", "name": "Les EGR peuvent-ils causer des troubles neurologiques ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des anomalies dans l'expression des EGR sont liées à des troubles neurologiques." } }, { "@type": "Question", "name": "Quelles sont les conséquences d'une surproduction d'EGR ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Une surproduction peut entraîner des tumeurs et des désordres de croissance cellulaire." } }, { "@type": "Question", "name": "Quels facteurs augmentent le risque de dysrégulation des EGR ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Des facteurs comme l'exposition à des toxines et des prédispositions génétiques augmentent le risque." } }, { "@type": "Question", "name": "Le stress influence-t-il les EGR ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le stress chronique peut affecter l'expression des EGR et la santé cellulaire." } }, { "@type": "Question", "name": "L'alimentation joue-t-elle un rôle dans les EGR ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation riche en antioxydants peut aider à réguler l'expression des EGR." } }, { "@type": "Question", "name": "Les infections affectent-elles les EGR ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Certaines infections peuvent moduler l'expression des EGR, influençant la réponse immunitaire." } }, { "@type": "Question", "name": "L'âge est-il un facteur de risque pour les EGR ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le vieillissement peut affecter l'expression des EGR et la régulation génétique." } } ] } ] }

Sources (10000 au total)

Implementation Science and Pediatric Diabetes: A Scoping Review of the State of the Literature and Recommendations for Future Research.

This scoping review aimed to identify implementation science (IS) research in pediatric diabetes, report integration of IS theory and terminology, and offer guidance for future research.... Of 23 papers identified, 19 were published since 2017 and 21 focused on type 1 diabetes. Most involved medical evidence-based practices (EBPs; n = 15), whereas fewer focused on psychosocial (n = 7) an...

Economic evaluation of implementation science outcomes in low- and middle-income countries: a scoping review.

Historically, the focus of cost-effectiveness analyses has been on the costs to operate and deliver interventions after their initial design and launch. The costs related to design and implementation ... We searched Web of Science and PubMed for papers published between January 1, 2010, and December 31, 2021, that included components of both implementation science and economic evaluation. Studies from... Six thousand nine hundred eighty-six studies were screened, of which 55 were included in full-text review and 23 selected for inclusion and data extraction. Most papers were theoretical, though some f... A sparse but growing literature explores the intersection of implementation science and economic evaluation. Key needs include more research in LMICs, greater consensus on the definition of implementa... The protocol for this manuscript was published on the Open Science Framework. It is available at: https://osf.io/ms5fa/ (DOI: 10.17605/OSF.IO/32EPJ)....

Generative AI in healthcare: an implementation science informed translational path on application, integration and governance.

Artificial intelligence (AI), particularly generative AI, has emerged as a transformative tool in healthcare, with the potential to revolutionize clinical decision-making and improve health outcomes. ... This article aims to provide a comprehensive overview of the use of generative AI in healthcare, focusing on the utility of the technology in healthcare and its translational application highlighting ... Generative AI has the potential to transform healthcare through automated systems, enhanced clinical decision-making and democratization of expertise with diagnostic support tools providing timely, pe... It is strongly argued in this article that generative AI can usher in tremendous healthcare progress, if introduced responsibly. Strategic adoption based on implementation science, incremental deploym...

Using implementation science frameworks to translate and adapt a pregnancy app for an emerging Latino community.

Digital mobile health (mHealth) applications are a popular form of prenatal education and care delivery in the U.S.; yet there are few Spanish language options for native speakers. Furthermore, existi... To adapt and translate an English-language pregnancy mobile health app to meet the language and cultural needs of Spanish-speaking Latino immigrants living in the United States.... We use a multi-step process, grounded in implementation science frameworks, to adapt and translate the contents of an existing pregnancy app. Interviews with stakeholders (n = 12) who advocate for the... The interviews with stakeholders revealed seven critical domains that need to be addressed in an adapted prenatal app: language and communication, financial concerns, social support, immigration statu... This work illustrates a process to adapt an mHealth pregnancy app to the needs of an emerging Latino community, by incorporating culturally sensitive Spanish language content while focusing on address...

Reducing Ileostomy Readmissions: Using Implementation Science to Evaluate the Adoption of a Quality Improvement Initiative.

Translating empirical evidence into clinical practice remains challenging. Prevention of morbidity from new ileostomies may serve as an example. Despite evidence demonstrating improvements in electrol... We used the Reach, Effectiveness, Adoption, Implementation, and Maintenance implementation science framework to identify barriers and facilitators in the adoption of a quality improvement initiative a... Qualitative interviews were conducted with stakeholders based on the domains of the Reach, Effectiveness, Adoption, Implementation, and Maintenance framework.... Participating community and academic hospitals across Michigan (n = 12).... Convenience sampling was used to recruit 25 key stakeholders, including wound, ostomy, and continence nurses; registered nurses; nurse practitioners; nurse managers; colorectal surgeons; surgery resid... Through qualitative content analysis, we located, analyzed, and identified patterns using the Reach, Effectiveness, Adoption, Implementation, and Maintenance framework.... We identified the following factors to increase the adoption of quality improvement initiatives at the provider level: 1) selection and coaching of champions, 2) broadening of multidisciplinary teams,... Limited to high-volume ileostomy surgery hospitals, did not include in-person site visits to each hospital before and after implementation, and did not consider the hospital- and patient-level factors... Integrating implementation science frameworks to rigorously study quality improvement initiatives may reveal the determinants of the widespread adoption of evidence-based practices.... ANTECEDENTES:Traducir la evidencia empírica a la práctica clínica sigue siendo un desafío. La prevención de la morbilidad por nuevas ileostomías puede servir como ejemplo. A pesar de la evidencia que ...

Increasing Uptake of Depression Screening and Treatment Guidelines in Cardiac Patients: A Behavioral and Implementation Science Approach to Developing a Theory-Informed, Multilevel Implementation Strategy.

Depression leads to poor health outcomes in patients with coronary heart disease (CHD). Despite guidelines recommending screening and treatment of depressed patients with CHD, few patients receive opt... We conducted a narrative review of barriers to depression screening and treatment in patients with CHD (ie, medications, exercise, cardiac rehabilitation, or therapy) comprising data from 748 study pa... We identified implementation barriers at the system/provider level (eg, Capability: knowledge; Opportunity: workflow integration; Motivation: ownership) and patient level (eg, Capability: knowledge; O... We applied implementation and behavioral science methods to identify implementation barriers and to develop a multilevel implementation strategy for increasing uptake of depression screening and treat...

Integrating Implementation Science in a Quality and Patient Safety Improvement Learning Collaborative: Essential Ingredients and Impact.

There is a current lack of research exploring the contextual factors of why and how quality improvement collaboratives (QICs) work. To this end, a mixed methods study was undertaken to improve our und... The authors used a mixed methods approach consisting of a written survey and 30-to-45-minute telephone interviews with collaborative team members, coaches, and senior leaders of participating safety i... Four themes emerged as the essential elements: (1) integrating implementation science into the QI/patient safety learning collaborative; (2) reinforcing of and opening eyes to implementation science b... This study's findings provide deeper insight into the "essential ingredients" (expert implementation specialist, coaches) grounded in an integrated approach that drew from QI, patient safety, and impl...

Sustained Effect of Clinical Decision Support for Heart Failure: A Natural Experiment Using Implementation Science.

In a randomized controlled trial, we found that applying implementation science (IS) methods and best practices in clinical decision support (CDS) design to create a locally customized, "enhanced" CDS... In this natural experiment of 28 primary care clinics, we compared clinics exposed to the commercial CDS (preperiod) to clinics exposed to the enhanced CDS (both periods). The primary effectiveness ou... There were 367 alerts for 183 unique patients and 171 unique clinicians (pre: March 2019-August 2019; post: October 2019-March 2020). The enhanced CDS increased prescribing by 26.1% compared with the ... Applying IS methods with CDS best practices was associated with improved and sustained clinician adoption and effectiveness compared with a commercially available CDS tool....

Time to re-envisage culturally responsive care: Intersection of participatory health research and implementation science.

In the context of widening societal diversity, culturally and linguistically diverse patients continue to experience inequities in healthcare access and deficiencies in standards of nursing care. Re-f... Discussion Paper.... A co-design case study is presented as an example of combining normalization process theory and participatory learning and action to investigate and support the implementation of culturally responsive... Enacting culturally responsive health care is inherently complex in that it is influenced by multiple interacting factors. Viewing culturally responsive care as a complex intervention and incorporatin... There is a need to move away from conventional approaches to conceptualizing and generating evidence on culturally responsive care. Incorporating participatory implementation methodologies can provide... The combination of participatory and implementation methodologies is both theoretically and empirically informed. Engaging stakeholders in the co-design and co-production of evidence and solutions to ... This work is part of a wider programme of participatory health research on migrant health, partnering with a non-governmental organization that supports migrants....