Titre : Polyangéite microscopique

Polyangéite microscopique : Questions médicales fréquentes

Termes MeSH sélectionnés :

Complement Inactivating Agents
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Polyangéite microscopique : Questions médicales les plus fréquentes", "headline": "Polyangéite microscopique : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Polyangéite microscopique : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-07-03", "dateModified": "2025-03-30", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Polyangéite microscopique" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Vascularites associées aux anticorps anti-cytoplasme des neutrophiles", "url": "https://questionsmedicales.fr/mesh/D056648", "about": { "@type": "MedicalCondition", "name": "Vascularites associées aux anticorps anti-cytoplasme des neutrophiles", "code": { "@type": "MedicalCode", "code": "D056648", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "C20.111.193" } } }, "about": { "@type": "MedicalCondition", "name": "Polyangéite microscopique", "alternateName": "Microscopic Polyangiitis", "code": { "@type": "MedicalCode", "code": "D055953", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Jason Jungsik Song", "url": "https://questionsmedicales.fr/author/Jason%20Jungsik%20Song", "affiliation": { "@type": "Organization", "name": "Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, and Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea." } }, { "@type": "Person", "name": "Sang-Won Lee", "url": "https://questionsmedicales.fr/author/Sang-Won%20Lee", "affiliation": { "@type": "Organization", "name": "Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, and Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea. sangwonlee@yuhs.ac." } }, { "@type": "Person", "name": "Sung Soo Ahn", "url": "https://questionsmedicales.fr/author/Sung%20Soo%20Ahn", "affiliation": { "@type": "Organization", "name": "Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea." } }, { "@type": "Person", "name": "Yong-Beom Park", "url": "https://questionsmedicales.fr/author/Yong-Beom%20Park", "affiliation": { "@type": "Organization", "name": "Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, and Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea." } }, { "@type": "Person", "name": "Taejun Yoon", "url": "https://questionsmedicales.fr/author/Taejun%20Yoon", "affiliation": { "@type": "Organization", "name": "Department of Medical Science, College of Medicine, BK21 Plus Project, Yonsei University, Seoul, Republic of Korea." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "Inactivation of the Complement Lectin Pathway by Candida tropicalis Secreted Aspartyl Protease-1.", "datePublished": "2022-08-28", "url": "https://questionsmedicales.fr/article/36063565", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.imbio.2022.152263" } }, { "@type": "ScholarlyArticle", "name": "Complement C3a receptor inactivation attenuates retinal degeneration induced by oxidative damage.", "datePublished": "2022-08-30", "url": "https://questionsmedicales.fr/article/36110094", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3389/fnins.2022.951491" } }, { "@type": "ScholarlyArticle", "name": "Evaluation and comparison of three virucidal agents on inactivation of Nipah virus.", "datePublished": "2022-07-05", "url": "https://questionsmedicales.fr/article/35790865", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1038/s41598-022-15228-0" } }, { "@type": "ScholarlyArticle", "name": "Importance of Inactivation Methodology in Enzymatic Processing of Raw Potato Starch: NaOCl as Efficient α-Amylase Inactivation Agent.", "datePublished": "2023-03-25", "url": "https://questionsmedicales.fr/article/37049710", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3390/molecules28072947" } }, { "@type": "ScholarlyArticle", "name": "Role of Surface Charge of Nanoscale Ultrasound Contrast Agents in Complement Activation and Phagocytosis.", "datePublished": "2022-12-05", "url": "https://questionsmedicales.fr/article/36506344", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.2147/IJN.S364381" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Maladies du système immunitaire", "item": "https://questionsmedicales.fr/mesh/D007154" }, { "@type": "ListItem", "position": 3, "name": "Maladies auto-immunes", "item": "https://questionsmedicales.fr/mesh/D001327" }, { "@type": "ListItem", "position": 4, "name": "Vascularites associées aux anticorps anti-cytoplasme des neutrophiles", "item": "https://questionsmedicales.fr/mesh/D056648" }, { "@type": "ListItem", "position": 5, "name": "Polyangéite microscopique", "item": "https://questionsmedicales.fr/mesh/D055953" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Polyangéite microscopique - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Polyangéite microscopique", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-15", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Polyangéite microscopique", "description": "Comment diagnostiquer la polyangéite microscopique ?\nQuels tests sanguins sont utilisés ?\nQuels symptômes orientent vers ce diagnostic ?\nLa biopsie est-elle toujours nécessaire ?\nQuels examens d'imagerie sont recommandés ?", "url": "https://questionsmedicales.fr/mesh/D055953?mesh_terms=Complement+Inactivating+Agents&page=4#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Polyangéite microscopique", "description": "Quels sont les symptômes courants ?\nLa polyangéite microscopique cause-t-elle des problèmes rénaux ?\nY a-t-il des symptômes respiratoires associés ?\nLes symptômes varient-ils d'un patient à l'autre ?\nPeut-on avoir des symptômes neurologiques ?", "url": "https://questionsmedicales.fr/mesh/D055953?mesh_terms=Complement+Inactivating+Agents&page=4#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Polyangéite microscopique", "description": "Peut-on prévenir la polyangéite microscopique ?\nQuels conseils de mode de vie peuvent aider ?\nLes vaccinations sont-elles recommandées ?\nFaut-il éviter certains médicaments ?\nLe suivi médical est-il important ?", "url": "https://questionsmedicales.fr/mesh/D055953?mesh_terms=Complement+Inactivating+Agents&page=4#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Polyangéite microscopique", "description": "Quels traitements sont utilisés pour cette maladie ?\nLes corticostéroïdes sont-ils efficaces ?\nCombien de temps dure le traitement ?\nY a-t-il des effets secondaires aux traitements ?\nDes traitements biologiques sont-ils disponibles ?", "url": "https://questionsmedicales.fr/mesh/D055953?mesh_terms=Complement+Inactivating+Agents&page=4#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Polyangéite microscopique", "description": "Quelles sont les complications possibles ?\nLa polyangéite microscopique peut-elle être mortelle ?\nComment prévenir les complications ?\nLes complications affectent-elles la qualité de vie ?\nY a-t-il des complications à long terme ?", "url": "https://questionsmedicales.fr/mesh/D055953?mesh_terms=Complement+Inactivating+Agents&page=4#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Polyangéite microscopique", "description": "Quels sont les facteurs de risque connus ?\nL'âge influence-t-il le risque ?\nLes infections peuvent-elles déclencher la maladie ?\nLe sexe joue-t-il un rôle dans le risque ?\nDes facteurs environnementaux sont-ils impliqués ?", "url": "https://questionsmedicales.fr/mesh/D055953?mesh_terms=Complement+Inactivating+Agents&page=4#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer la polyangéite microscopique ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic repose sur des analyses sanguines, des biopsies et des examens d'imagerie." } }, { "@type": "Question", "name": "Quels tests sanguins sont utilisés ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests incluent la recherche d'anticorps anti-MPO et des marqueurs d'inflammation." } }, { "@type": "Question", "name": "Quels symptômes orientent vers ce diagnostic ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Symptômes comme la fatigue, la fièvre, et des douleurs articulaires peuvent indiquer la maladie." } }, { "@type": "Question", "name": "La biopsie est-elle toujours nécessaire ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Non, la biopsie n'est pas toujours nécessaire, mais elle peut confirmer le diagnostic." } }, { "@type": "Question", "name": "Quels examens d'imagerie sont recommandés ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Les IRM et les scanners peuvent aider à visualiser les atteintes organiques." } }, { "@type": "Question", "name": "Quels sont les symptômes courants ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent fatigue, fièvre, éruptions cutanées et douleurs musculaires." } }, { "@type": "Question", "name": "La polyangéite microscopique cause-t-elle des problèmes rénaux ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle peut entraîner une insuffisance rénale aiguë due à l'inflammation des vaisseaux rénaux." } }, { "@type": "Question", "name": "Y a-t-il des symptômes respiratoires associés ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des symptômes comme la toux et des douleurs thoraciques peuvent survenir." } }, { "@type": "Question", "name": "Les symptômes varient-ils d'un patient à l'autre ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'intensité et la combinaison des symptômes peuvent varier considérablement." } }, { "@type": "Question", "name": "Peut-on avoir des symptômes neurologiques ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des symptômes comme des maux de tête ou des troubles de la vision peuvent apparaître." } }, { "@type": "Question", "name": "Peut-on prévenir la polyangéite microscopique ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Il n'existe pas de méthode de prévention spécifique, mais un suivi médical régulier est conseillé." } }, { "@type": "Question", "name": "Quels conseils de mode de vie peuvent aider ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Adopter un mode de vie sain, éviter le tabac et gérer le stress peuvent être bénéfiques." } }, { "@type": "Question", "name": "Les vaccinations sont-elles recommandées ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les vaccinations peuvent aider à prévenir certaines infections, surtout sous traitement immunosuppresseur." } }, { "@type": "Question", "name": "Faut-il éviter certains médicaments ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains médicaments peuvent aggraver la maladie, il est donc important de consulter un médecin." } }, { "@type": "Question", "name": "Le suivi médical est-il important ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un suivi régulier permet de surveiller l'évolution de la maladie et d'ajuster le traitement." } }, { "@type": "Question", "name": "Quels traitements sont utilisés pour cette maladie ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des corticostéroïdes et des immunosuppresseurs pour réduire l'inflammation." } }, { "@type": "Question", "name": "Les corticostéroïdes sont-ils efficaces ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils sont souvent efficaces pour contrôler l'inflammation et soulager les symptômes." } }, { "@type": "Question", "name": "Combien de temps dure le traitement ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "La durée du traitement varie, mais peut durer plusieurs mois à plusieurs années." } }, { "@type": "Question", "name": "Y a-t-il des effets secondaires aux traitements ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les effets secondaires peuvent inclure des infections, des troubles digestifs et des problèmes osseux." } }, { "@type": "Question", "name": "Des traitements biologiques sont-ils disponibles ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des traitements biologiques comme le rituximab peuvent être utilisés dans certains cas." } }, { "@type": "Question", "name": "Quelles sont les complications possibles ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent l'insuffisance rénale, les infections et les problèmes pulmonaires." } }, { "@type": "Question", "name": "La polyangéite microscopique peut-elle être mortelle ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, sans traitement approprié, elle peut entraîner des complications graves et potentiellement mortelles." } }, { "@type": "Question", "name": "Comment prévenir les complications ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Un traitement précoce et un suivi régulier sont essentiels pour prévenir les complications." } }, { "@type": "Question", "name": "Les complications affectent-elles la qualité de vie ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les complications peuvent significativement affecter la qualité de vie des patients." } }, { "@type": "Question", "name": "Y a-t-il des complications à long terme ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des complications à long terme peuvent inclure des problèmes rénaux chroniques et des troubles pulmonaires." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque connus ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des antécédents familiaux, le tabagisme et certaines infections." } }, { "@type": "Question", "name": "L'âge influence-t-il le risque ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la polyangéite microscopique est plus fréquente chez les adultes âgés de 50 à 70 ans." } }, { "@type": "Question", "name": "Les infections peuvent-elles déclencher la maladie ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines infections virales ou bactériennes peuvent être des déclencheurs." } }, { "@type": "Question", "name": "Le sexe joue-t-il un rôle dans le risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la maladie est légèrement plus fréquente chez les hommes que chez les femmes." } }, { "@type": "Question", "name": "Des facteurs environnementaux sont-ils impliqués ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exposition à certains produits chimiques ou médicaments peut augmenter le risque." } } ] } ] }

Sources (10000 au total)

Role of Surface Charge of Nanoscale Ultrasound Contrast Agents in Complement Activation and Phagocytosis.

To prepare nanoscale ultrasound contrast agents (Nano-UCAs) and examine the role of their surface charge in complement activation and phagocytosis.... We analyzed serum proteins present in the corona formed on Nano-UCAs and evaluated two important protein markers of complement activation (C3 and SC5b-9). The effect of surface charge on phagocytosis ... When Nano-UCAs were incubated with human serum, they were opsonized by various blood proteins, especially C3. Highly charged Nano-UCAs, whether positive or negative, were favorably opsonized by comple... Charged Nano-UCAs show a higher tendency to activated complement system, and are efficiently engulfed by macrophages. The present results provide meaningful insights into the role of the surface charg...

Bacterial Inactivation Studies in Shrimp Pond Water by using Different Disinfectant Agents.

Aquaculture water plays an important role in the dissemination of antibiotic-resistant bacteria during harvest of shrimps. Mitigation of bacteria through discharge is essential to prevent disseminatio... To study the effect of different disinfectant agent's viz., chlorine, Fenton's reagent, and hydrogen peroxide (H2O2) on inactivation of bacteria from shrimp pond water.... The water samples were subjected to treatment with various concentrations of chlorine (0.0, 1.0, 2.5, 5.0 and 10.0 mg L-1), Fenton's reagent (1:10 mM ratio of Fe2+:H2O2; 2:20, 3:30, 4:40, 5:50) and H2... The results indicated that all the disinfecting agents inactivated both the total heterotrophic bacteria and tetracycline-resistant bacteria with increased concentrations and time. At the end of 60 mi... The study revealed that disinfection agents can be successfully employed in the inactivation of antibiotic-resistant bacteria discharged through aquaculture water. Among three disinfection agents, Fen... Bacterial inactivation studies were carried with Chlorination, Fenton's reagent, and Hydrogen peroxide. The highest decrease in HPC (2.65 log) and tetracycline-resistant bacterial (1.66 log) was notic...

Clinical efficacy and safety of switching from eculizumab to ravulizumab in adult patients with aHUS- real-world data.

The complement factor 5 (C5)-inhibitor eculizumab has been established as standard-of-care for the treatment of atypical hemolytic uremic syndrome (aHUS). In 2021, the long-acting C5-inhibitor ravuliz... This multicenter, retrospective data analysis of 32 adult patients with aHUS (including 10 kidney transplant recipients) treated with eculizumab for at least three months and switched to ravulizumab a... Mean age (range) at ravulizumab initiation was 41 years (19-78 years) and 59% of the patients were female. Genetic analysis was available for all patients with 72% showing a pathogenic variant. Median... This is the largest, non-industry derived, multi-center retrospective analysis of adult patients with aHUS switching C5-inhibitor treatment from eculizumab to ravulizumab in the real-world setting. Sw...