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"name": "Facteurs de risque",
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"@type": "Question",
"name": "Comment diagnostiquer la polyangéite microscopique ?",
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"text": "Le diagnostic repose sur des analyses sanguines, des biopsies et des examens d'imagerie."
}
},
{
"@type": "Question",
"name": "Quels tests sanguins sont utilisés ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests incluent la recherche d'anticorps anti-MPO et des marqueurs d'inflammation."
}
},
{
"@type": "Question",
"name": "Quels symptômes orientent vers ce diagnostic ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Symptômes comme la fatigue, la fièvre, et des douleurs articulaires peuvent indiquer la maladie."
}
},
{
"@type": "Question",
"name": "La biopsie est-elle toujours nécessaire ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, la biopsie n'est pas toujours nécessaire, mais elle peut confirmer le diagnostic."
}
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{
"@type": "Question",
"name": "Quels examens d'imagerie sont recommandés ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les IRM et les scanners peuvent aider à visualiser les atteintes organiques."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes courants ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent fatigue, fièvre, éruptions cutanées et douleurs musculaires."
}
},
{
"@type": "Question",
"name": "La polyangéite microscopique cause-t-elle des problèmes rénaux ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut entraîner une insuffisance rénale aiguë due à l'inflammation des vaisseaux rénaux."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes respiratoires associés ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des symptômes comme la toux et des douleurs thoraciques peuvent survenir."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils d'un patient à l'autre ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'intensité et la combinaison des symptômes peuvent varier considérablement."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des symptômes neurologiques ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des symptômes comme des maux de tête ou des troubles de la vision peuvent apparaître."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir la polyangéite microscopique ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de méthode de prévention spécifique, mais un suivi médical régulier est conseillé."
}
},
{
"@type": "Question",
"name": "Quels conseils de mode de vie peuvent aider ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Adopter un mode de vie sain, éviter le tabac et gérer le stress peuvent être bénéfiques."
}
},
{
"@type": "Question",
"name": "Les vaccinations sont-elles recommandées ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les vaccinations peuvent aider à prévenir certaines infections, surtout sous traitement immunosuppresseur."
}
},
{
"@type": "Question",
"name": "Faut-il éviter certains médicaments ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments peuvent aggraver la maladie, il est donc important de consulter un médecin."
}
},
{
"@type": "Question",
"name": "Le suivi médical est-il important ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi régulier permet de surveiller l'évolution de la maladie et d'ajuster le traitement."
}
},
{
"@type": "Question",
"name": "Quels traitements sont utilisés pour cette maladie ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des corticostéroïdes et des immunosuppresseurs pour réduire l'inflammation."
}
},
{
"@type": "Question",
"name": "Les corticostéroïdes sont-ils efficaces ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils sont souvent efficaces pour contrôler l'inflammation et soulager les symptômes."
}
},
{
"@type": "Question",
"name": "Combien de temps dure le traitement ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La durée du traitement varie, mais peut durer plusieurs mois à plusieurs années."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires aux traitements ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les effets secondaires peuvent inclure des infections, des troubles digestifs et des problèmes osseux."
}
},
{
"@type": "Question",
"name": "Des traitements biologiques sont-ils disponibles ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des traitements biologiques comme le rituximab peuvent être utilisés dans certains cas."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent l'insuffisance rénale, les infections et les problèmes pulmonaires."
}
},
{
"@type": "Question",
"name": "La polyangéite microscopique peut-elle être mortelle ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, sans traitement approprié, elle peut entraîner des complications graves et potentiellement mortelles."
}
},
{
"@type": "Question",
"name": "Comment prévenir les complications ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un traitement précoce et un suivi régulier sont essentiels pour prévenir les complications."
}
},
{
"@type": "Question",
"name": "Les complications affectent-elles la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les complications peuvent significativement affecter la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications à long terme ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications à long terme peuvent inclure des problèmes rénaux chroniques et des troubles pulmonaires."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque connus ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux, le tabagisme et certaines infections."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la polyangéite microscopique est plus fréquente chez les adultes âgés de 50 à 70 ans."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles déclencher la maladie ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines infections virales ou bactériennes peuvent être des déclencheurs."
}
},
{
"@type": "Question",
"name": "Le sexe joue-t-il un rôle dans le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la maladie est légèrement plus fréquente chez les hommes que chez les femmes."
}
},
{
"@type": "Question",
"name": "Des facteurs environnementaux sont-ils impliqués ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certains produits chimiques ou médicaments peut augmenter le risque."
}
}
]
}
]
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Dyslipidemia is a well-established cardiovascular disease (CVD) risk factor, although its association with mortality is less clear. This study aimed to assess the association between established dysli...
Prospective cohort study of 1,479 men aged 59.7±10.7 years was conducted between 1987 and 2012. At baseline, dyslipidemia markers of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C)...
Mean and standard deviations of TC, LDL-C and HDL-C were 199.5±45.2, 149.4±47.4 and 44.3±12.2 mg/dL, respectively. During 8.9±4.5 years follow-up, 284 participants died. Compared to TC <200 mg/dL, lev...
In reference to established dyslipidemia criteria, this study showed that higher TC and LDL-C were independently and paradoxically associated with lower risk of all-cause mortality and longer survival...
Cardiopulmonary exercise testing (CPET) remains poorly understood and, consequently, largely underused in respiratory medicine. In addition to a widespread lack of knowledge of integrative physiology,...
Despite the numerous recent advancements in therapy, heart failure (HF) remains a principle cause of both morbidity and mortality. HF with preserved ejection fraction (HFpEF), a condition that shares ...
Multiple sclerosis (MS) is a chronic demyelinating inflammatory disorder of the central nervous system that may affect respiratory system at the later stages of the disease. The aim of our study was t...
25 pwMS and 16 healthy controls were included in this study. Pulmonary function tests were performed and were followed by proper cardiopulmonary exercise testing with the use of treadmill. Quality of ...
The mean age of the patient group was 38.4 ± 8.2 years. Spirometric values were within normal limits, and so did lung diffusion capacity, while maximal voluntary ventilation was reduced. In cardiopulm...
Our study showed that the main cardiopulmonary exercise testing parameters were affected in ambulatory pwMS, even without evidence of respiratory symptoms. Therefore, these people should be evaluated ...
Although walking is the most common exercise modality in daily life for most humans, running and cycling are the most applied exercise modalities during maximal oxygen uptake (VO<inf>2max</inf>) testi...
Sixteen participants (25±3 years, 172±9 cm, 69±15 kg, and VO<inf>2max</inf> 50±4 mL/kg/min) performed four incremental running- and walking VO<inf>2max</inf> tests (two tests in each condition) within...
The walking protocol achieved similar reliability values for absolute and relative VO<inf>2max</inf> when compared to the running condition. No significant differences in VO<inf>2max</inf> were observ...
Although the present participants achieved 2-3% lower VO<inf>2max</inf> when the walking test protocol was applied, walking seems to be a promising exercise-modality alternative during VO<inf>2max</in...
the main objective of this study was to evaluate the test-retest reliability of two different functional electromechanical dynamometry (FEMD)-controlled squat training protocols....
twenty-eight healthy young adults volunteered to participate in this study. They attended the laboratory on four different days and performed four sessions: two of three sets of 12 repetitions at 75% ...
reliability was very high for ROM (CV: 3.72%, ICC: 0.95), MDS (CV: 1.09%, ICC: 1.00), PDS (CV: 1.97%, ICC: 1.00), and W (CV: 4.69%, ICC: 1.00) conditions at 50% 1RM and for ROM (CV: 3.90%, ICC: 0.95),...
this study demonstrates that FEMD is a reliable instrument to measure ROM, MDS, PDS, MV, PV, PV, MP, MP, W, and I during both squat protocols (50 and 75% 1RM) in healthy young adults....
Cardiopulmonary exercise testing (CPET), and its primary outcome of peak oxygen uptake (VO...
Twenty-six people with ILD were recruited, and 21 successfully completed three CPETs. Of these, 17 completed two valid CPETs within a 3-month window, and 11 completed two valid CPETs within a 6-month ...
Every participant (100%) who successfully exercised to volitional exhaustion produced a maximal, and therefore valid, CPET. Approximately 20% of participants presented with a plateau in VO...
This work has, for the first time, fully characterised how patients with ILD respond to CPET in terms of primary and secondary verification criteria, and generated novel repeatability data that will p...
BACKGROUND This study aimed to analyze the correlations among peak oxygen uptake (VO2) in cardiopulmonary exercise test (CPX), incremental shuttle walking test (ISWT), and 6-minute walking test (6MWT)...
Exaggerated exercise blood pressure (BP) is linked to cardiovascular disease (CVD). Although evening chronotypes have greater CVD risk than morning (Morn) types, it is unknown if exercise BP differs i...
This study aimed to explore the application of cardiopulmonary exercise testing in coronary artery disease (CAD) patients, evaluate its impact on exercise ability and cardiopulmonary function in patie...
Fifty CHD patients after percutaneous coronary intervention (PCI) were recruited and randomly enrolled into the control (Ctrl) group and intervention (Int) group. Routine health education and health e...
Compared with those in the Ctrl group, the levels of serum total cholesterol (TC), triglycerides (TGs), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) decreased in the Int group, wh...
RT training can reduce postoperative blood lipid and quantitative load levels in CAD patients and improve adverse mood. Furthermore, it can improve patients' cardiopulmonary function, cardiopulmonary ...