{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Érythrokératodermie variabilis : Questions médicales les plus fréquentes",
"headline": "Érythrokératodermie variabilis : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Érythrokératodermie variabilis : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-06-24",
"dateModified": "2025-03-21",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Érythrokératodermie variabilis"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Maladies génétiques de la peau",
"url": "https://questionsmedicales.fr/mesh/D012873",
"about": {
"@type": "MedicalCondition",
"name": "Maladies génétiques de la peau",
"code": {
"@type": "MedicalCode",
"code": "D012873",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C17.800.827"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Érythrokératodermie variabilis",
"alternateName": "Erythrokeratodermia Variabilis",
"code": {
"@type": "MedicalCode",
"code": "D056266",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Yuuki Kodama",
"url": "https://questionsmedicales.fr/author/Yuuki%20Kodama",
"affiliation": {
"@type": "Organization",
"name": "Institute of Agricultural and Life Sciences, Academic Assembly, Shimane University, Matsue-shi, Japan. kodama@life.shimane-u.ac.jp."
}
},
{
"@type": "Person",
"name": "Matthew E M Yunik",
"url": "https://questionsmedicales.fr/author/Matthew%20E%20M%20Yunik",
"affiliation": {
"@type": "Organization",
"name": "Department of Biology, University of Saskatchewan, Saskatoon, SK, Canada."
}
},
{
"@type": "Person",
"name": "Neil B Chilton",
"url": "https://questionsmedicales.fr/author/Neil%20B%20Chilton",
"affiliation": {
"@type": "Organization",
"name": "Department of Biology, University of Saskatchewan, Saskatoon, SK, Canada."
}
},
{
"@type": "Person",
"name": "Chulantha P Diyes",
"url": "https://questionsmedicales.fr/author/Chulantha%20P%20Diyes",
"affiliation": {
"@type": "Organization",
"name": "Department of Biology, University of Saskatchewan, Saskatoon, SK, Canada."
}
},
{
"@type": "Person",
"name": "Mirye Park",
"url": "https://questionsmedicales.fr/author/Mirye%20Park",
"affiliation": {
"@type": "Organization",
"name": "Protist Research Team, Microbial Research Department, Nakdonggang National Institute of Biological Resources, Sangju, 37242, Republic of Korea."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "A randomized controlled trial evaluating the effects of motivational interviewing in new hearing aid users (MI-HAT): study protocol for a randomized controlled trial.",
"datePublished": "2023-05-22",
"url": "https://questionsmedicales.fr/article/37217960",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s13063-023-07352-7"
}
},
{
"@type": "ScholarlyArticle",
"name": "Protocol for a randomized controlled trial: exercise-priming of CBT for depression (the CBT+ trial).",
"datePublished": "2024-10-07",
"url": "https://questionsmedicales.fr/article/39375728",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s13063-024-08495-x"
}
},
{
"@type": "ScholarlyArticle",
"name": "Understanding explanatory and pragmatic trials: Examples from randomized controlled trials on vertebroplasty.",
"datePublished": "2022-12-23",
"url": "https://questionsmedicales.fr/article/36566693",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.neuchi.2022.101403"
}
},
{
"@type": "ScholarlyArticle",
"name": "Emulating Randomized Controlled Trials with Hybrid Control Arms in Oncology: A Case Study.",
"datePublished": "2023-01-22",
"url": "https://questionsmedicales.fr/article/36606735",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1002/cpt.2841"
}
},
{
"@type": "ScholarlyArticle",
"name": "Topical sirolimus solution for lingual microcystic lymphatic malformations in children and adults (TOPGUN): study protocol for a multicenter, randomized, assessor-blinded, controlled, stepped-wedge clinical trial.",
"datePublished": "2022-07-08",
"url": "https://questionsmedicales.fr/article/35804404",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s13063-022-06365-y"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Maladies de la peau et du tissu conjonctif",
"item": "https://questionsmedicales.fr/mesh/D017437"
},
{
"@type": "ListItem",
"position": 3,
"name": "Maladies de la peau",
"item": "https://questionsmedicales.fr/mesh/D012871"
},
{
"@type": "ListItem",
"position": 4,
"name": "Maladies génétiques de la peau",
"item": "https://questionsmedicales.fr/mesh/D012873"
},
{
"@type": "ListItem",
"position": 5,
"name": "Érythrokératodermie variabilis",
"item": "https://questionsmedicales.fr/mesh/D056266"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Érythrokératodermie variabilis - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Érythrokératodermie variabilis",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-13",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Érythrokératodermie variabilis",
"description": "Comment diagnostiquer l'érythrokératodermie variabilis ?\nQuels tests sont utilisés pour le diagnostic ?\nQuels signes cliniques indiquent cette maladie ?\nL'érythrokératodermie variabilis est-elle héréditaire ?\nPeut-on confondre cette maladie avec d'autres ?",
"url": "https://questionsmedicales.fr/mesh/D056266?mesh_terms=Randomized+Controlled+Trials+as+Topic&page=4#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Érythrokératodermie variabilis",
"description": "Quels sont les principaux symptômes ?\nLes symptômes varient d'une personne à l'autre ?\nY a-t-il des symptômes associés ?\nLes symptômes s'aggravent-ils avec le temps ?\nLes symptômes peuvent-ils être déclenchés par des facteurs externes ?",
"url": "https://questionsmedicales.fr/mesh/D056266?mesh_terms=Randomized+Controlled+Trials+as+Topic&page=4#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Érythrokératodermie variabilis",
"description": "Peut-on prévenir l'érythrokératodermie variabilis ?\nComment gérer les symptômes au quotidien ?\nY a-t-il des conseils pour la peau ?\nLes soins de la peau sont-ils importants ?\nLes patients doivent-ils éviter certains aliments ?",
"url": "https://questionsmedicales.fr/mesh/D056266?mesh_terms=Randomized+Controlled+Trials+as+Topic&page=4#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Érythrokératodermie variabilis",
"description": "Quels traitements sont disponibles ?\nLes traitements sont-ils efficaces ?\nDes traitements alternatifs existent-ils ?\nLes traitements nécessitent-ils un suivi médical ?\nY a-t-il des effets secondaires aux traitements ?",
"url": "https://questionsmedicales.fr/mesh/D056266?mesh_terms=Randomized+Controlled+Trials+as+Topic&page=4#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Érythrokératodermie variabilis",
"description": "Quelles complications peuvent survenir ?\nL'érythrokératodermie variabilis augmente-t-elle le risque de cancer ?\nLes complications affectent-elles la qualité de vie ?\nDes complications psychologiques peuvent-elles survenir ?\nLes complications nécessitent-elles une intervention médicale ?",
"url": "https://questionsmedicales.fr/mesh/D056266?mesh_terms=Randomized+Controlled+Trials+as+Topic&page=4#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Érythrokératodermie variabilis",
"description": "Quels sont les facteurs de risque connus ?\nL'environnement joue-t-il un rôle ?\nLes infections peuvent-elles déclencher des symptômes ?\nLe stress influence-t-il la maladie ?\nY a-t-il des groupes à risque spécifique ?",
"url": "https://questionsmedicales.fr/mesh/D056266?mesh_terms=Randomized+Controlled+Trials+as+Topic&page=4#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer l'érythrokératodermie variabilis ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic repose sur l'examen clinique et l'historique familial, parfois confirmé par une biopsie cutanée."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques peuvent être effectués pour identifier des mutations spécifiques associées à la maladie."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques indiquent cette maladie ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des plaques rouges et squameuses sur la peau, souvent avec des zones de kératose, sont typiques."
}
},
{
"@type": "Question",
"name": "L'érythrokératodermie variabilis est-elle héréditaire ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle est généralement transmise de manière autosomique dominante dans les familles."
}
},
{
"@type": "Question",
"name": "Peut-on confondre cette maladie avec d'autres ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut être confondue avec d'autres dermatoses comme le psoriasis ou l'ichtyose."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux symptômes ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des plaques rouges, des démangeaisons et une peau squameuse."
}
},
{
"@type": "Question",
"name": "Les symptômes varient d'une personne à l'autre ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'intensité et l'étendue des symptômes peuvent varier considérablement entre les individus."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes associés ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des anomalies des ongles et des cheveux peuvent également être observées chez certains patients."
}
},
{
"@type": "Question",
"name": "Les symptômes s'aggravent-ils avec le temps ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent fluctuer, mais ils ont tendance à persister tout au long de la vie."
}
},
{
"@type": "Question",
"name": "Les symptômes peuvent-ils être déclenchés par des facteurs externes ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des facteurs comme le stress, les infections ou les irritants cutanés peuvent aggraver les symptômes."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir l'érythrokératodermie variabilis ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Étant une maladie génétique, il n'existe pas de méthode de prévention connue."
}
},
{
"@type": "Question",
"name": "Comment gérer les symptômes au quotidien ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'utilisation régulière d'émollients et l'évitement des irritants cutanés peuvent aider."
}
},
{
"@type": "Question",
"name": "Y a-t-il des conseils pour la peau ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est conseillé de garder la peau hydratée et de protéger les zones affectées du soleil."
}
},
{
"@type": "Question",
"name": "Les soins de la peau sont-ils importants ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des soins appropriés peuvent réduire l'inconfort et améliorer l'apparence de la peau."
}
},
{
"@type": "Question",
"name": "Les patients doivent-ils éviter certains aliments ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'y a pas de régime spécifique, mais une alimentation équilibrée peut soutenir la santé globale."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des émollients, des corticostéroïdes topiques et des thérapies systémiques."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils efficaces ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements peuvent aider à soulager les symptômes, mais il n'existe pas de cure définitive."
}
},
{
"@type": "Question",
"name": "Des traitements alternatifs existent-ils ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies comme la photothérapie peuvent être envisagées pour certains patients."
}
},
{
"@type": "Question",
"name": "Les traitements nécessitent-ils un suivi médical ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi régulier est essentiel pour ajuster les traitements et surveiller les effets secondaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires aux traitements ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains traitements peuvent entraîner des effets secondaires comme l'amincissement de la peau."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des infections cutanées peuvent survenir en raison de la peau endommagée et des lésions."
}
},
{
"@type": "Question",
"name": "L'érythrokératodermie variabilis augmente-t-elle le risque de cancer ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'y a pas de preuve claire que cette maladie augmente le risque de cancer de la peau."
}
},
{
"@type": "Question",
"name": "Les complications affectent-elles la qualité de vie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes et les complications peuvent avoir un impact significatif sur la qualité de vie."
}
},
{
"@type": "Question",
"name": "Des complications psychologiques peuvent-elles survenir ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'impact esthétique et les démangeaisons peuvent entraîner des problèmes psychologiques."
}
},
{
"@type": "Question",
"name": "Les complications nécessitent-elles une intervention médicale ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines complications peuvent nécessiter des soins médicaux supplémentaires pour être gérées."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque connus ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux de la maladie sont le principal facteur de risque identifié."
}
},
{
"@type": "Question",
"name": "L'environnement joue-t-il un rôle ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Bien que l'environnement ne soit pas un facteur direct, des irritants peuvent aggraver les symptômes."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles déclencher des symptômes ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines infections cutanées peuvent exacerber les symptômes de la maladie."
}
},
{
"@type": "Question",
"name": "Le stress influence-t-il la maladie ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut aggraver les symptômes et provoquer des poussées cutanées."
}
},
{
"@type": "Question",
"name": "Y a-t-il des groupes à risque spécifique ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les personnes ayant des antécédents familiaux sont plus susceptibles de développer la maladie."
}
}
]
}
]
}
Hearing loss is the third leading global cause of disability and is associated with poorer quality of life. Hearing aids are often recommended for hearing loss; however, hearing aid uptake and use rat...
A multi-center, prospective, randomized patient-blind controlled trial with a pre- and post-tests design. New hearing aid users ≥ 18 years of age will be recruited from Vancouver, Canada. They will be...
This trial is designed to evaluate the efficacy of one-on-one MI in improving hearing aid use in new adult users in the short and long terms. Results will contribute to the evidence on whether MI coun...
ClinicalTrials.gov NCT04673565 . Registered on 17 December 2020....
Depression is a leading cause of disability worldwide, and treatments could be more effective. Identifying methods to improve treatment success has the potential to reduce disease burden dramatically....
The CBT + trial will be a parallel-arm randomized controlled trial that will recruit 40 adult participants with DSM-5 diagnosed depression (verified with clinical interview) via referrals, mass emails...
The novel approach of priming CBT with moderate-intensity aerobic exercise evaluated in a randomized controlled trial (CBT + trial) has the potential to demonstrate the usefulness of exercise as an au...
ClinicalTrials.gov NCT06001346 . Registered on August 21, 2023....
To better understand the explanatory-pragmatic distinction in the design and interpretation of randomized controlled trials (RCTs)....
We review the explanatory-pragmatic distinction in clinical trial design. We use the PRECIS-2 tool to evaluate the trial design of selected RCTs on percutaneous vertebroplasty for osteoporotic vertebr...
The selection of criteria and the scoring of multiple PRECIS domains were subjective and thus debatable. The pragmascope patterns of various vertebroplasty trials were heterogeneous. Many trials had b...
The results of a trial cannot be interpreted without understanding the various design choices made along the explanatory-pragmatic spectrum....
This proof-of-concept study retrospectively assessed the feasibility of applying a hybrid control arm design to a completed phase III randomized controlled trial (RCT; CheckMate-057) in advanced non-s...
Lingual microcystic lymphatic malformations (LMLMs) are rare congenital vascular malformations presenting as clusters of cysts filled with lymph fluid or blood. Even small well-limited lesions can be ...
This is a randomized, multicentric study using an individually randomized stepped-wedge design over 24 weeks to evaluate topical application of a 1 mg/mL sirolimus solution once daily, on LMLM, versus...
Given the disappointing state of current treatment options in LMLMs, topical sirolimus could become firstline therapy in treating LMLMs if its efficacy and safety were to be demonstrated....
ClinicalTrials.gov NCT04128722 . Registered on 24 September 2019. EudraCT: EUCTR2019-001530-33-FR Sponsor (University Hospital Center of Tours - CHRU Tours): DR190041-TOPGUN French regulatory authorit...
Allergic rhinitis (AR) is the inflammation of the membranes lining the nose due to allergen exposure and is characterized by sneezing, nasal congestion, itching of the nose, or postnasal discharge. Th...
The primary aim is to assess the efficacy of Ayurvedic management for AR (or vataja pratishyaya) by comparing it to a conventional control group. The secondary aims are to determine the mean change in...
This ongoing study is an open-label randomized controlled interventional trial, with a sample size of 90 both in the trial and standard control group (including dropouts, 20%), and will be carried out...
As of May 2024, 72 patients have been enrolled in both groups. Data analysis should be completed by February 2025. The study will be reported following standard guidelines for reporting randomized con...
The Ayurvedic approach could be an evidence-based therapeutic tactic for the management of AR....
Clinical Trials Registry India CTRI/2023/06/053395; https://tinyurl.com/564d2zz8....
DERR1-10.2196/56063....
Contemporary management of uncomplicated type B aortic dissections (uTBAD) is based on the acuity and various morphological features. Medical therapy is mandatory, while the risks of early thoracic en...
The trial is a randomized, open-label, superiority clinical trial with parallel assignment of subjects at 23 clinical sites in Denmark, Norway, Sweden, Finland, and Iceland. Eligibility includes patie...
This trial will evaluate the primary question of whether early TEVAR improves survival at 5 years among uTBAD patients. Moreover, the costs and the impact on quality of life should provide sorely need...
ClinicalTrials.gov NCT05215587. Registered on January 31, 2022....
With advances in antiretroviral therapy, people with HIV (PWH) are living longer and are less likely to die from AIDS-related complications. Yet, prior research has shown that smoking is often not add...
The current study is a type 1 hybrid effectiveness-implementation trial to evaluate the impact of a proactive, opt-out tobacco treatment intervention on cessation outcomes and advance understanding of...
This study will examine a novel approach to optimizing tobacco treatment delivery for PWH. Integrating effectiveness and implementation results will help define best practices for engaging PWH with ev...
ClinicalTrials.gov: NCT05019495 (August 24, 2021)....
Glaucoma is a chronic progressive optic neuropathy that necessitates lifelong treatment to reduce the decline of the optic nerve. Due to the extended and continuous treatments required for patients, c...
The primary objective of this study is to conduct a single-center randomized control trial involving patients with glaucoma. Acupuncture will be evaluated as an adjunctive therapy. The trial aims to e...
In this single-center randomized controlled trial, participants (N=50) with primary open-angle glaucoma will be randomly assigned to the treatment group, receiving ophthalmic acupuncture with "De Qi" ...
Recruitment of participants for the trial commenced on June 28, 2023. A total of 10 participants have been enrolled to test the feasibility of the experiment. We anticipate that the preliminary data f...
This trial uses rigorous methodology and comprehensive outcome measurements to assess the clinical efficacy of acupuncture as an adjunctive therapy for glaucoma, providing valuable insights for future...
ClinicalTrials.gov NCT05753137; https://clinicaltrials.gov/study/NCT05753137....
DERR1-10.2196/57888....
Investigators often conduct randomized controlled trials (RCTs) at multiple centers/sites when determining the effect of a treatment or an intervention. Diversifying recruitment across multiple instit...