Titre : Jumonji Domain-Containing Histone Demethylases

Jumonji Domain-Containing Histone Demethylases : Questions médicales fréquentes

Termes MeSH sélectionnés :

Avoidance Learning
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Jumonji Domain-Containing Histone Demethylases : Questions médicales les plus fréquentes", "headline": "Jumonji Domain-Containing Histone Demethylases : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Jumonji Domain-Containing Histone Demethylases : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-07-10", "dateModified": "2025-04-06", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Jumonji Domain-Containing Histone Demethylases" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Dioxygenases", "url": "https://questionsmedicales.fr/mesh/D049308", "about": { "@type": "MedicalCondition", "name": "Dioxygenases", "code": { "@type": "MedicalCode", "code": "D049308", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D08.811.682.690.416" } } }, "about": { "@type": "MedicalCondition", "name": "Jumonji Domain-Containing Histone Demethylases", "alternateName": "Jumonji Domain-Containing Histone Demethylases", "code": { "@type": "MedicalCode", "code": "D056484", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Danica Galonić Fujimori", "url": "https://questionsmedicales.fr/author/Danica%20Galoni%C4%87%20Fujimori", "affiliation": { "@type": "Organization", "name": "Department of Cellular and Molecular Pharmacology, University of California San Francisco; San Francisco, CA 94158, USA; Department of Pharmaceutical Chemistry, University of California San Francisco; San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California San Francisco; San Francisco, CA 94158, USA. Electronic address: danica.fujimori@ucsf.edu." } }, { "@type": "Person", "name": "James E Longbotham", "url": "https://questionsmedicales.fr/author/James%20E%20Longbotham", "affiliation": { "@type": "Organization", "name": "Department of Cellular and Molecular Pharmacology, University of California San Francisco, 600 16th Street, Genentech Hall, San Francisco, California 94158, United States." } }, { "@type": "Person", "name": "Feng Li", "url": "https://questionsmedicales.fr/author/Feng%20Li", "affiliation": { "@type": "Organization", "name": "Department of Cell Biology, Key Laboratory of Cell Biology, National Health Commission of the PRC, Shenyang, China." } }, { "@type": "Person", "name": "Christopher J Schofield", "url": "https://questionsmedicales.fr/author/Christopher%20J%20Schofield", "affiliation": { "@type": "Organization", "name": "Chemistry Research Laboratory , University of Oxford , 12 Mansfield Road , Oxford OX1 3TA , United Kingdom." } }, { "@type": "Person", "name": "Anthony Tumber", "url": "https://questionsmedicales.fr/author/Anthony%20Tumber", "affiliation": { "@type": "Organization", "name": "Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford UK christopher.schofield@chem.ox.ac.uk lennart.brewitz@chem.ox.ac.uk." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "Relation among, trait anxiety, intolerance to uncertainty and early maltreatment experiences on fear discrimination learning and avoidance generalization online task.", "datePublished": "2023-06-05", "url": "https://questionsmedicales.fr/article/37343426", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.jbtep.2023.101886" } }, { "@type": "ScholarlyArticle", "name": "Policy abstraction as a predictor of cognitive effort avoidance.", "datePublished": "2023-08-24", "url": "https://questionsmedicales.fr/article/37616076", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1037/xge0001449" } }, { "@type": "ScholarlyArticle", "name": "Safety signals reinforce instrumental avoidance in humans.", "datePublished": "2024-09-11", "url": "https://questionsmedicales.fr/article/39260876", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1101/lm.053914.123" } }, { "@type": "ScholarlyArticle", "name": "Foster children avoidance-related interactive behaviors with caregivers.", "datePublished": "2022-11-25", "url": "https://questionsmedicales.fr/article/36442420", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.chiabu.2022.105973" } }, { "@type": "ScholarlyArticle", "name": "A network perspective on real-life threat, anxiety, and avoidance.", "datePublished": "2023-08-02", "url": "https://questionsmedicales.fr/article/37531080", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1002/jclp.23575" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Enzymes et coenzymes", "item": "https://questionsmedicales.fr/mesh/D045762" }, { "@type": "ListItem", "position": 3, "name": "Enzymes", "item": "https://questionsmedicales.fr/mesh/D004798" }, { "@type": "ListItem", "position": 4, "name": "Oxidoreductases", "item": "https://questionsmedicales.fr/mesh/D010088" }, { "@type": "ListItem", "position": 5, "name": "Oxygénases", "item": "https://questionsmedicales.fr/mesh/D010105" }, { "@type": "ListItem", "position": 6, "name": "Dioxygenases", "item": "https://questionsmedicales.fr/mesh/D049308" }, { "@type": "ListItem", "position": 7, "name": "Jumonji Domain-Containing Histone Demethylases", "item": "https://questionsmedicales.fr/mesh/D056484" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Jumonji Domain-Containing Histone Demethylases - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Jumonji Domain-Containing Histone Demethylases", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-08", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Jumonji Domain-Containing Histone Demethylases", "description": "Comment diagnostiquer une dysfonction des Jumonji ?\nQuels marqueurs biologiques sont associés aux Jumonji ?\nLes biopsies sont-elles utiles pour le diagnostic ?\nQuels tests sanguins sont recommandés ?\nY a-t-il des tests d'imagerie pour ces enzymes ?", "url": "https://questionsmedicales.fr/mesh/D056484?mesh_terms=Avoidance+Learning&page=2#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Jumonji Domain-Containing Histone Demethylases", "description": "Quels symptômes sont liés aux anomalies des Jumonji ?\nLes troubles neurologiques sont-ils associés ?\nY a-t-il des symptômes cutanés associés ?\nLes symptômes varient-ils selon le type de Jumonji ?\nLes symptômes sont-ils réversibles ?", "url": "https://questionsmedicales.fr/mesh/D056484?mesh_terms=Avoidance+Learning&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Jumonji Domain-Containing Histone Demethylases", "description": "Peut-on prévenir les dysfonctionnements des Jumonji ?\nLes tests génétiques peuvent-ils aider à la prévention ?\nY a-t-il des vaccins pour prévenir ces dysfonctionnements ?\nL'éducation génétique est-elle importante ?\nLes conseils diététiques peuvent-ils aider ?", "url": "https://questionsmedicales.fr/mesh/D056484?mesh_terms=Avoidance+Learning&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Jumonji Domain-Containing Histone Demethylases", "description": "Quels traitements sont disponibles pour les dysfonctionnements des Jumonji ?\nLes médicaments peuvent-ils cibler les Jumonji ?\nY a-t-il des traitements naturels recommandés ?\nLes traitements sont-ils personnalisés ?\nLes thérapies combinées sont-elles efficaces ?", "url": "https://questionsmedicales.fr/mesh/D056484?mesh_terms=Avoidance+Learning&page=2#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Jumonji Domain-Containing Histone Demethylases", "description": "Quelles complications peuvent survenir avec les dysfonctionnements des Jumonji ?\nLes complications sont-elles graves ?\nY a-t-il des complications à long terme ?\nLes complications sont-elles réversibles ?\nLes complications varient-elles selon le type de Jumonji ?", "url": "https://questionsmedicales.fr/mesh/D056484?mesh_terms=Avoidance+Learning&page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Jumonji Domain-Containing Histone Demethylases", "description": "Quels sont les facteurs de risque pour les dysfonctionnements des Jumonji ?\nL'âge est-il un facteur de risque ?\nLes antécédents familiaux jouent-ils un rôle ?\nL'exposition à des toxines est-elle un facteur ?\nLe mode de vie influence-t-il le risque ?", "url": "https://questionsmedicales.fr/mesh/D056484?mesh_terms=Avoidance+Learning&page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une dysfonction des Jumonji ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests génétiques et des analyses d'expression génique peuvent être utilisés." } }, { "@type": "Question", "name": "Quels marqueurs biologiques sont associés aux Jumonji ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les niveaux de méthylation des histones et l'expression des gènes sont des marqueurs clés." } }, { "@type": "Question", "name": "Les biopsies sont-elles utiles pour le diagnostic ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les biopsies peuvent aider à évaluer l'expression des Jumonji dans les tissus." } }, { "@type": "Question", "name": "Quels tests sanguins sont recommandés ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des tests pour mesurer les niveaux de protéines associées aux Jumonji peuvent être effectués." } }, { "@type": "Question", "name": "Y a-t-il des tests d'imagerie pour ces enzymes ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Non, l'imagerie ne permet pas de diagnostiquer directement les Jumonji." } }, { "@type": "Question", "name": "Quels symptômes sont liés aux anomalies des Jumonji ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Des troubles de croissance, des anomalies développementales et des cancers peuvent survenir." } }, { "@type": "Question", "name": "Les troubles neurologiques sont-ils associés ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des dysfonctionnements neurologiques peuvent être liés à des mutations des Jumonji." } }, { "@type": "Question", "name": "Y a-t-il des symptômes cutanés associés ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Certaines anomalies cutanées peuvent être observées, notamment dans des syndromes spécifiques." } }, { "@type": "Question", "name": "Les symptômes varient-ils selon le type de Jumonji ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, différents types de Jumonji peuvent entraîner des symptômes variés selon leur fonction." } }, { "@type": "Question", "name": "Les symptômes sont-ils réversibles ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Cela dépend de la gravité et de la nature de la dysfonction des Jumonji." } }, { "@type": "Question", "name": "Peut-on prévenir les dysfonctionnements des Jumonji ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention est difficile, mais un mode de vie sain peut réduire les risques." } }, { "@type": "Question", "name": "Les tests génétiques peuvent-ils aider à la prévention ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les tests génétiques peuvent identifier les individus à risque de dysfonctionnements." } }, { "@type": "Question", "name": "Y a-t-il des vaccins pour prévenir ces dysfonctionnements ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Non, il n'existe pas de vaccins spécifiques pour prévenir les dysfonctionnements des Jumonji." } }, { "@type": "Question", "name": "L'éducation génétique est-elle importante ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'éducation sur les risques génétiques peut aider à la prévention et à la détection précoce." } }, { "@type": "Question", "name": "Les conseils diététiques peuvent-ils aider ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée peut soutenir la santé cellulaire, mais ne prévient pas directement." } }, { "@type": "Question", "name": "Quels traitements sont disponibles pour les dysfonctionnements des Jumonji ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Des thérapies géniques et des inhibiteurs spécifiques sont en cours d'étude." } }, { "@type": "Question", "name": "Les médicaments peuvent-ils cibler les Jumonji ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains médicaments expérimentaux ciblent les Jumonji pour traiter des cancers." } }, { "@type": "Question", "name": "Y a-t-il des traitements naturels recommandés ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Des approches nutritionnelles et phytothérapeutiques sont explorées, mais peu prouvées." } }, { "@type": "Question", "name": "Les traitements sont-ils personnalisés ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les traitements peuvent être adaptés en fonction des mutations spécifiques des Jumonji." } }, { "@type": "Question", "name": "Les thérapies combinées sont-elles efficaces ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Des études montrent que les thérapies combinées peuvent améliorer les résultats cliniques." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec les dysfonctionnements des Jumonji ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des cancers, des troubles métaboliques et des anomalies développementales peuvent survenir." } }, { "@type": "Question", "name": "Les complications sont-elles graves ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines complications peuvent être potentiellement mortelles si non traitées." } }, { "@type": "Question", "name": "Y a-t-il des complications à long terme ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Des complications chroniques peuvent se développer, affectant la qualité de vie." } }, { "@type": "Question", "name": "Les complications sont-elles réversibles ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être gérées, mais d'autres peuvent être irréversibles." } }, { "@type": "Question", "name": "Les complications varient-elles selon le type de Jumonji ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les complications peuvent varier en fonction du type de Jumonji impliqué." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour les dysfonctionnements des Jumonji ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs génétiques, environnementaux et liés au mode de vie peuvent influencer le risque." } }, { "@type": "Question", "name": "L'âge est-il un facteur de risque ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains dysfonctionnements des Jumonji sont plus fréquents avec l'âge." } }, { "@type": "Question", "name": "Les antécédents familiaux jouent-ils un rôle ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents familiaux de maladies génétiques augmentent le risque." } }, { "@type": "Question", "name": "L'exposition à des toxines est-elle un facteur ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exposition à certaines toxines peut augmenter le risque de dysfonctionnements." } }, { "@type": "Question", "name": "Le mode de vie influence-t-il le risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un mode de vie malsain peut accroître le risque de dysfonctionnements des Jumonji." } } ] } ] }

Sources (10000 au total)

Relation among, trait anxiety, intolerance to uncertainty and early maltreatment experiences on fear discrimination learning and avoidance generalization online task.

Early aversive experiences, which have been associated with elevated anxiety and intolerance of uncertainty (IUS), may contribute negatively to fear conditioning learning. The aim of the present study... We adapted an avoidance procedure in an online fear learning task. Two pictures of different lamp colors (CS+) were first associated with two aversive images (US), while a third color was not (CS-). N... Aversive early experiences were positively related to trait anxiety and intolerance of uncertainty. The results of the task further suggested that maltreatment experience contributes to be more attent... Online experiments implies some loss of control over subjects and environment that can threaten internal validity. Likewise, the commitment of participants may be low.... Results suggest that early aversive experience and anxiety could contribute to the development of IUS, which likely contributes to the development of avoidance behavior....

Foster children avoidance-related interactive behaviors with caregivers.

A lot of the research concerning foster children - often children who have suffered maltreatment in the family home - has focused on internalized and externalized symptoms. Few studies, however, have ... The purpose of this study is to explore the Emotion Regulation Strategies (ERS) of children in foster care and to highlight those most commonly employed in family or placement contexts. The parents' a... An in-depth analysis of observation sequences was performed. Three data collection times, spaced across a period of 6 months (t1, t2 and t3), were included in the observation protocol. Each observatio... Children tended to be readily distracted when interacting with adults, and more particularly so with their parents. While they tended to display relatively normative processes with a foster carer, the... This study highlights the prevalence of distraction behavior in foster children during their interactions with caregivers, and offers an insight into how structured interactions provide a framework th...

A network perspective on real-life threat, anxiety, and avoidance.

Anxiety, approach, and avoidance motivation crucially influence mental and physical health, especially when environments are stressful. The interplay between anxiety and behavioral motivation is modul... A total of 436 participants who were matched on age and gender (218 psychotherapy patients, 218 online-recruited nonpatients) completed an online survey assessing these factors in response to the COVI... The resulting cross-sectional psychological network revealed a complex pattern with multiple positive (e.g., between trait anxiety, avoidance motivation, and avoidance behavior) and negative associati...

Avoidance behaviour modulates but does not condition phonophobia in migraine.

Past studies do not account for avoidance behaviour in migraine as a potential confounder of phonophobia.... To analyse whether phonophobia is partially driven by avoidance behaviour when using the classic methodology (method of limits).... This is a case-control study where we tested phonophobia in a cohort of high-frequency/chronic migraine patients (15.5 ± 0.74 headache days/month) and non-headache controls. Auditory stimuli, delivere... In this study, we successfully replicate previously reported reduction in sound aversion threshold using three different methods in a group of 35 patients and 25 controls (p < 0.0001). Avoidance be... Avoidance behaviour can exacerbate phonophobia. The current methodology to measure phonophobia needs to be revised....

More engagement in inefficient avoidance through partial reinforcement.

In anxiety-related disorders, excessive avoidance often coexists with an impaired sense of control over external threats. In contrast, lab studies have shown that avoidance responding increase with hi... We conducted an experiment that additionally included a completely uncontrollable threat, and we manipulated the reinforcement rate of the avoidance response to the (semi-)controllable threat (75% ver... The 100% group showed increased avoidance to the controllable threat and decreased avoidance to the unavoidable threat over learning. Interestingly, compared to the 100% group, the 75% group displayed... Only two reinforcement rates of effective avoidance were included, which may limit the generalizability of the current findings. Perceived control was not directly measured.... Lower reinforcement rates create ambiguity between effective and ineffective situations of avoidance, which engenders generalization of unpredictability from effective to ineffective situation, thereb...

An experimental test of the effects of acute sleep deprivation on affect and avoidance.

Avoidance and sleep have been identified as mechanisms involved in the development and maintenance of many mental health disorders. However, there has been little research into the relation between sl... To address this, a randomized controlled experiment using behavioral and self-report measures of affect and avoidance was conducted. Compared to a control group, we hypothesized that sleep-deprived in... Repeated measures ANOVAs demonstrated negative affectivity and self-reported avoidance increased, and positive affectivity decreased, from pre-to post-manipulation in the sleep loss condition as expec... This study emphasized internal validity over generalizability. Additionally, the at-home sleep deprivation limited researcher control over the overnight activities of participants.... Results replicate prior work on the affective consequences of sleep deprivation and highlight a discrepancy between the effect of sleep deprivation on behavioral avoidance toward a specific stimulus c...