Acute chest syndrome in sickle cell disease.
Sickle cell disease (SCD) is an autosomal recessive disorder altering the shape of red blood cells, causing harmful obstructions in blood vessels, therefore altering normal blood flow. SCD can escalat...
Syndrome thoracique aigu : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment diagnostique-t-on le syndrome thoracique aigu ?
Le diagnostic repose sur des symptômes cliniques et des examens d'imagerie comme la radiographie.
#2
Quels tests sont utilisés pour confirmer le diagnostic ?
Des tests sanguins, une radiographie thoracique et parfois un scanner peuvent être utilisés.
#3
Quels sont les signes cliniques du syndrome thoracique aigu ?
Les signes incluent douleur thoracique, toux, fièvre et difficultés respiratoires.
#4
Le syndrome thoracique aigu peut-il être confondu avec d'autres maladies ?
Oui, il peut être confondu avec une pneumonie ou une embolie pulmonaire.
#5
Quelle est l'importance de l'imagerie dans le diagnostic ?
L'imagerie aide à visualiser les infiltrats pulmonaires et à évaluer la gravité.
Symptômes 5
#1
Quels sont les symptômes principaux du syndrome thoracique aigu ?
Les symptômes incluent douleur thoracique, toux, fièvre et dyspnée.
#2
La fièvre est-elle un symptôme fréquent ?
Oui, la fièvre est souvent présente et peut indiquer une infection associée.
#3
Peut-on avoir des douleurs abdominales avec ce syndrome ?
Oui, des douleurs abdominales peuvent survenir en raison de l'irritation diaphragmatique.
#4
Les symptômes peuvent-ils varier d'un patient à l'autre ?
Oui, l'intensité et la combinaison des symptômes peuvent varier selon les individus.
#5
Comment la dyspnée se manifeste-t-elle dans ce syndrome ?
La dyspnée se manifeste par une difficulté à respirer, souvent aggravée par l'effort.
Prévention 5
#1
Comment peut-on prévenir le syndrome thoracique aigu ?
La prévention inclut une bonne hydratation, la vaccination et l'évitement des déclencheurs.
#2
Les vaccinations sont-elles importantes pour les patients ?
Oui, les vaccinations contre la pneumonie et la grippe sont recommandées.
#3
Quels déclencheurs doivent être évités ?
Les déclencheurs incluent le stress, l'exposition au froid et la déshydratation.
#4
L'éducation des patients est-elle cruciale ?
Oui, l'éducation sur la gestion de la drépanocytose aide à prévenir les complications.
#5
Le suivi médical régulier est-il nécessaire ?
Oui, un suivi régulier permet de surveiller l'état de santé et d'anticiper les crises.
Traitements 5
#1
Quels traitements sont recommandés pour le syndrome thoracique aigu ?
Les traitements incluent l'oxygénothérapie, les analgésiques et les antibiotiques si infection.
#2
L'hydratation joue-t-elle un rôle dans le traitement ?
Oui, une bonne hydratation est essentielle pour prévenir la déshydratation et améliorer la circulation.
#3
Des transfusions sanguines sont-elles nécessaires ?
Oui, des transfusions peuvent être nécessaires pour traiter l'anémie sévère associée.
#4
Les corticostéroïdes sont-ils utilisés dans le traitement ?
Oui, les corticostéroïdes peuvent être utilisés pour réduire l'inflammation pulmonaire.
#5
Quel est le rôle des antibiotiques dans le traitement ?
Les antibiotiques sont administrés pour traiter ou prévenir les infections pulmonaires.
Complications 5
#1
Quelles sont les complications possibles du syndrome thoracique aigu ?
Les complications incluent l'insuffisance respiratoire, les infections et les embolies.
#2
L'insuffisance respiratoire est-elle une complication fréquente ?
Oui, l'insuffisance respiratoire peut survenir et nécessite une attention médicale immédiate.
#3
Les infections pulmonaires sont-elles courantes ?
Oui, les infections pulmonaires sont fréquentes et peuvent aggraver l'état du patient.
#4
Le syndrome peut-il entraîner des séquelles à long terme ?
Oui, des séquelles comme des troubles respiratoires chroniques peuvent se développer.
#5
Les embolies pulmonaires sont-elles une préoccupation ?
Oui, les embolies pulmonaires peuvent survenir et nécessitent une intervention rapide.
Facteurs de risque 5
#1
Quels sont les principaux facteurs de risque du syndrome thoracique aigu ?
Les facteurs incluent la drépanocytose, les infections respiratoires et la déshydratation.
#2
L'âge influence-t-il le risque de syndrome thoracique aigu ?
Oui, les enfants et les jeunes adultes atteints de drépanocytose sont plus à risque.
#3
Le tabagisme est-il un facteur de risque ?
Oui, le tabagisme peut aggraver les symptômes et augmenter le risque de complications.
#4
Les voyages en altitude augmentent-ils le risque ?
Oui, les voyages en altitude peuvent déclencher des crises chez les patients drépanocytaires.
#5
Le stress émotionnel peut-il aggraver la condition ?
Oui, le stress émotionnel est un facteur déclenchant connu pour le syndrome thoracique aigu.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 20/05/2026
Contenu vérifié selon les dernières recommandations médicales
Auteurs principaux
None None
3 publications dans cette catégorie
Publications dans "Syndrome thoracique aigu" :
-
ACR Appropriateness Criteria® Chest Pain-Possible Acute Coronary Syndrome.
Journal of the American College of Radiology : JACR
-
An Italian registry of chest pain patients in the emergency department: clinical predictors of acute coronary syndrome.
Minerva medica
-
Low-risk factors for severe bacterial infection and acute chest syndrome in children with sickle cell disease.
Pediatric blood & cancer 2019-02-10
Kerry Morrone
2 publications dans cette catégorie
Affiliations :
- Department of Pediatrics, Children's Hospital at Montefiore Bronx, New York, USA.
Publications dans "Syndrome thoracique aigu" :
-
Prevent Acute Chest Syndrome checklist (PACScheck): A quality improvement initiative to reduce acute chest syndrome.
Pediatric blood & cancer 2024-10-17
-
Associating a standardized reporting tool for chest radiographs with clinical complications in pediatric acute chest syndrome.
Pediatric pulmonology 2023-09-06
Kaitlin Strumph
2 publications dans cette catégorie
Affiliations :
- Department of Pediatrics, Children's Hospital at Montefiore Bronx, New York, USA.
Publications dans "Syndrome thoracique aigu" :
-
Prevent Acute Chest Syndrome checklist (PACScheck): A quality improvement initiative to reduce acute chest syndrome.
Pediatric blood & cancer 2024-10-17
-
Associating a standardized reporting tool for chest radiographs with clinical complications in pediatric acute chest syndrome.
Pediatric pulmonology 2023-09-06
Deepa Manwani
2 publications dans cette catégorie
Affiliations :
- Department of Pediatrics, Children's Hospital at Montefiore Bronx, New York, USA.
Publications dans "Syndrome thoracique aigu" :
-
Prevent Acute Chest Syndrome checklist (PACScheck): A quality improvement initiative to reduce acute chest syndrome.
Pediatric blood & cancer 2024-10-17
-
Associating a standardized reporting tool for chest radiographs with clinical complications in pediatric acute chest syndrome.
Pediatric pulmonology 2023-09-06
Michael L Rinke
2 publications dans cette catégorie
Affiliations :
- Department of Pediatrics, Children's Hospital at Montefiore Bronx, New York, USA.
Publications dans "Syndrome thoracique aigu" :
-
Prevent Acute Chest Syndrome checklist (PACScheck): A quality improvement initiative to reduce acute chest syndrome.
Pediatric blood & cancer 2024-10-17
-
Associating a standardized reporting tool for chest radiographs with clinical complications in pediatric acute chest syndrome.
Pediatric pulmonology 2023-09-06
Neha Bhasin
2 publications dans cette catégorie
Affiliations :
- Division of Hematology, Department of Pediatrics, UCSF Benioff Children's Hospital Oakland, USA. Electronic address: neha.bhasin@ucsf.edu.
Publications dans "Syndrome thoracique aigu" :
-
Acute Chest Syndrome in Sickle Cell Disease.
Transfusion medicine reviews 2023-09-03
-
Physician perspectives about the diagnosis and management of acute chest syndrome.
Transfusion 2024-10-07
Ravi Sarode
2 publications dans cette catégorie
Affiliations :
- Department of Pathology and Internal Medicine (Hematology/Oncology), UT Southwestern Medical Center, USA.
Publications dans "Syndrome thoracique aigu" :
-
Acute Chest Syndrome in Sickle Cell Disease.
Transfusion medicine reviews 2023-09-03
-
Physician perspectives about the diagnosis and management of acute chest syndrome.
Transfusion 2024-10-07
Jennifer M Knight-Madden
2 publications dans cette catégorie
Affiliations :
- Caribbean Institute for Health Research - Sickle Cell Unit, The University of the West Indies, Kingston, Jamaica.
Publications dans "Syndrome thoracique aigu" :
-
Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease.
The Cochrane database of systematic reviews 2022-12-02
-
Antibiotics for treating acute chest syndrome in people with sickle cell disease.
The Cochrane database of systematic reviews 2019-09-18
Michelle C Williams
2 publications dans cette catégorie
Affiliations :
- Centre for Cardiovascular Sciences, University of Edinburgh, Edinburgh, UK.
Publications dans "Syndrome thoracique aigu" :
-
Role of computed tomography cardiac angiography in acute chest pain syndromes.
Heart (British Cardiac Society) 2023-08-24
-
Controversies in Diagnostic Imaging of Patients With Suspected Stable and Acute Chest Pain Syndromes.
JACC. Cardiovascular imaging
Vincent Labbé
2 publications dans cette catégorie
Affiliations :
- Service de Médecine Intensive Réanimation, Département Médico-Universitaire APPROCHES, Hôpital Tenon, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
- Faculté de Médecine, Sorbonne Université, Paris, France.
Publications dans "Syndrome thoracique aigu" :
-
Endothelial dysfunction and hypercoagulability in severe sickle-cell acute chest syndrome.
ERJ open research 2021-12-13
-
Extracorporeal Life Support for Severe Acute Chest Syndrome in Adult Sickle Cell Disease: A Preliminary Report.
Critical care medicine
Muriel Fartoukh
2 publications dans cette catégorie
Affiliations :
- Service de Médecine Intensive Réanimation, Département Médico-Universitaire APPROCHES, Hôpital Tenon, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
- Faculté de Médecine, Sorbonne Université, Paris, France.
Publications dans "Syndrome thoracique aigu" :
-
Endothelial dysfunction and hypercoagulability in severe sickle-cell acute chest syndrome.
ERJ open research 2021-12-13
-
Extracorporeal Life Support for Severe Acute Chest Syndrome in Adult Sickle Cell Disease: A Preliminary Report.
Critical care medicine
Esther de Groot
2 publications dans cette catégorie
Affiliations :
- Julius Center for Health Sciences and Primary Care.
Publications dans "Syndrome thoracique aigu" :
-
Chest discomfort at night and risk of acute coronary syndrome: cross-sectional study of telephone conversations.
The British journal of general practice : the journal of the Royal College of General Practitioners
-
Chest discomfort at night and risk of acute coronary syndrome: cross-sectional study of telephone conversations.
Family practice
Joseph L Simonson
2 publications dans cette catégorie
Affiliations :
- Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, 232890Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.
Publications dans "Syndrome thoracique aigu" :
-
Hemoglobin Target and Transfusion Modality for Adult Patients With Sickle Cell Disease Acute Chest Syndrome.
Journal of intensive care medicine 2020-12-14
-
Enlarged pulmonary artery on computed tomography and respiratory failure in sickle cell disease acute chest syndrome.
Pulmonary circulation 2021-05-21
Gulrukh Z Zaidi
2 publications dans cette catégorie
Affiliations :
- Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, 232890Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.
Publications dans "Syndrome thoracique aigu" :
-
Hemoglobin Target and Transfusion Modality for Adult Patients With Sickle Cell Disease Acute Chest Syndrome.
Journal of intensive care medicine 2020-12-14
-
Enlarged pulmonary artery on computed tomography and respiratory failure in sickle cell disease acute chest syndrome.
Pulmonary circulation 2021-05-21
Jeffrey Lebensburger
2 publications dans cette catégorie
Affiliations :
- Department of Pediatrics, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Publications dans "Syndrome thoracique aigu" :
-
Nocturnal hypoxemia measured by polysomnogram is associated with acute chest syndrome in pediatric sickle cell disease.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
-
Acute chest syndrome in pediatric sickle cell disease: Associations with racial composition and neighborhood deprivation.
Pediatric blood & cancer 2021-01-06
Ammar Saadoon Alishlash
2 publications dans cette catégorie
Affiliations :
- Department of Pediatrics, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Publications dans "Syndrome thoracique aigu" :
-
Nocturnal hypoxemia measured by polysomnogram is associated with acute chest syndrome in pediatric sickle cell disease.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
-
Acute chest syndrome in pediatric sickle cell disease: Associations with racial composition and neighborhood deprivation.
Pediatric blood & cancer 2021-01-06
Michael W Sjoding
2 publications dans cette catégorie
Affiliations :
- Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Publications dans "Syndrome thoracique aigu" :
-
Robust segmentation of lung in chest x-ray: applications in analysis of acute respiratory distress syndrome.
BMC medical imaging 2020-10-15
-
Deep learning to detect acute respiratory distress syndrome on chest radiographs: a retrospective study with external validation.
The Lancet. Digital health 2021-04-20
Edward H Suh
2 publications dans cette catégorie
Affiliations :
- Department of Emergency Medicine, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY.
Publications dans "Syndrome thoracique aigu" :
-
Updating a Healthcare System-wide Clinical Pathway for Managing Chest Pain and Acute Coronary Syndromes.
Critical pathways in cardiology 2023-09-28
-
An Updated Healthcare System-Wide Clinical Pathway for Managing Patients With Chest Pain and Acute Coronary Syndromes.
Critical pathways in cardiology
Osman R Sayan
2 publications dans cette catégorie
Affiliations :
- Department of Emergency Medicine, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY.
Publications dans "Syndrome thoracique aigu" :
-
Updating a Healthcare System-wide Clinical Pathway for Managing Chest Pain and Acute Coronary Syndromes.
Critical pathways in cardiology 2023-09-28
-
An Updated Healthcare System-Wide Clinical Pathway for Managing Patients With Chest Pain and Acute Coronary Syndromes.
Critical pathways in cardiology
Gerald Neuberg
2 publications dans cette catégorie
Affiliations :
- Division of Cardiology, Department of Medicine, NewYork-Presbyterian Hospital/Allen Hospital, New York, NY.
Publications dans "Syndrome thoracique aigu" :
-
Updating a Healthcare System-wide Clinical Pathway for Managing Chest Pain and Acute Coronary Syndromes.
Critical pathways in cardiology 2023-09-28
-
An Updated Healthcare System-Wide Clinical Pathway for Managing Patients With Chest Pain and Acute Coronary Syndromes.
Critical pathways in cardiology
Sources (10000 au total)
Associating a standardized reporting tool for chest radiographs with clinical complications in pediatric acute chest syndrome.
Acute chest syndrome (ACS) is an important cause of morbidity in sickle cell disease (SCD). A standardized tool for reporting chest radiographs in pediatric SCD patients did not previously exist.... To analyze the interobserver agreement among pediatric radiologists' interpretations for pediatric ACS chest radiographs utilizing a standardized reporting tool. We also explored the association of ra... This was a retrospective cohort study of pediatric ACS admissions from a single institution in 2019. ICD-10 codes identified 127 ACS admissions. Two radiologists independently interpreted the chest ra... Interobserver agreement was moderate to near-perfect across variables, with κ analysis showing near-perfect agreement for opacity reported in the right upper lobe (0.84), substantial agreement for rig... The standardized reporting tool showed moderate to near-perfect agreement between radiologists. LLL opacity, and pleural effusion were associated with increased risk of ACS complications....
Respiratory management of acute chest syndrome in children with sickle cell disease.
Acute chest syndrome (ACS) is a leading cause of respiratory distress and hospitalisation in children with sickle cell disease (SCD). The aetiology is multifactorial and includes fat embolism, venous ...
Lipid and hemolysis parameters predicting acute chest syndrome in adulthood with sickle cell disease.
Sickle cell disease (SCD) is a lifelong blood disorder affecting approximately 100,000 people in the United States and is one of the most common monogenic diseases. A serious complication of SCD is ac...
Prevent Acute Chest Syndrome checklist (PACScheck): A quality improvement initiative to reduce acute chest syndrome.
Acute chest syndrome (ACS) is a life-threatening complication of sickle cell disease (SCD). The Prevent Acute Chest Syndrome checklist (PACScheck) was created to drive appropriate ordering of opioids,... Decrease the development of ACS by 5% in a hospitalized pediatric SCD population.... A multidisciplinary team conducted a quality improvement (QI) project between April 2020 and August 2021 on an inpatient pediatric hematology unit. At-risk hospitalizations were patients with SCD who ... A total of 483 at-risk hospitalizations were identified in the 12 months prior and 363 during the study period. A g chart demonstrated that fewer encounters developed ACS during PACScheck. A p chart d... Development of ACS can be reduced by implementing a best-practices checklist (PACScheck) on an inpatient pediatric hematology unit with a multidisciplinary team....
Crisis in the Chest: Acute Chest Syndrome as a Sequela of Tricuspid Valve Endocarditis.
The management of acute chest syndrome (ACS) in sickle cell disease occurring concurrently with pulmonary embolism resulting from tricuspid valve endocarditis poses an atypical challenge. We present a...
Acute Chest Syndrome in Sickle Cell Disease.
Acute chest syndrome (ACS) is the leading cause of mortality among individuals with sickle cell disease (SCD) accounting for 25% of all deaths. The etiologies and clinical manifestations of ACS are va...
Physician perspectives about the diagnosis and management of acute chest syndrome.
Acute chest syndrome (ACS) is the leading cause of mortality, accounting for 25% of all deaths among individuals with sickle cell disease (SCD). There is a lack of evidence-based laboratory and clinic... To better understand physician practices for the management of ACS in the United States, we created an ACS Working Group including hematology and transfusion medicine physicians from four different SC... Out of 455 physicians who received the survey, 195 responded (response rate = 43%). The respondents were primarily hematology/oncology physicians. The responses showed wide variability among physician... Based on our results, we conclude that ACS is diagnosed and managed inconsistently among expert physicians, especially in their transfusion practices due to a lack of consensus on risk stratification ...
[Preclinical loading in patients with acute chest pain and acute coronary syndrome - PRELOAD survey].
Guidelines on myocardial infarction (MI) recommend antithrombotic and anticoagulatory treatment at time of diagnosis. MI with ST segment elevation (STEMI) is mostly a certain diagnosis. Acute coronary... Assessment of prehospital loading with aspirin and heparin depending on ACS subtype and pretreatment with oral anticoagulants.... The PRELOAD survey was a nationwide German study. STEMI/NSTE-ACS scenarios were designed and varied in pretreatment: I) no pretreatment, II) new oral anticoagulants (NOAC), III) vitamin K antagonist (... A total of 708 emergency physicians were included. In NSTE-ACS without pretreatment, 79% chose loading (p < 0.001). ASA + UFH (71.4%) was the preferred option. In corresponding STEMI scenario, 100% ch... Prehospital loading was the preferred treatment strategy despite the diagnostic uncertainty in NSTE-ACS and guidelines recommending loading at time of diagnosis. Pretreatment with oral anticoagulants ...
Role of computed tomography cardiac angiography in acute chest pain syndromes.
Use of CT coronary angiography (CTCA) to evaluate chest pain has rapidly increased over the recent years. While its utility in the diagnosis of coronary artery disease in stable chest pain syndromes i...