Titre : Antigène CD274

Antigène CD274 : Questions médicales fréquentes

Termes MeSH sélectionnés :

Rotator Cuff Injuries
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Antigène CD274 : Questions médicales les plus fréquentes", "headline": "Antigène CD274 : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Antigène CD274 : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-05-16", "dateModified": "2025-02-10", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Antigène CD274" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Antigènes B7", "url": "https://questionsmedicales.fr/mesh/D060887", "about": { "@type": "MedicalCondition", "name": "Antigènes B7", "code": { "@type": "MedicalCode", "code": "D060887", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D23.529.168" } } }, "about": { "@type": "MedicalCondition", "name": "Antigène CD274", "alternateName": "B7-H1 Antigen", "code": { "@type": "MedicalCode", "code": "D060890", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Soldano Ferrone", "url": "https://questionsmedicales.fr/author/Soldano%20Ferrone", "affiliation": { "@type": "Organization", "name": "Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA." } }, { "@type": "Person", "name": "Haidong Dong", "url": "https://questionsmedicales.fr/author/Haidong%20Dong", "affiliation": { "@type": "Organization", "name": "Department of Urology, Mayo Clinic, Rochester, MN, USA." } }, { "@type": "Person", "name": "Hongwei Du", "url": "https://questionsmedicales.fr/author/Hongwei%20Du", "affiliation": { "@type": "Organization", "name": "Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA." } }, { "@type": "Person", "name": "Barbara Savoldo", "url": "https://questionsmedicales.fr/author/Barbara%20Savoldo", "affiliation": { "@type": "Organization", "name": "Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA; Department of Pediatrics, University of North Carolina, Chapel Hill, NC, USA." } }, { "@type": "Person", "name": "Gianpietro Dotti", "url": "https://questionsmedicales.fr/author/Gianpietro%20Dotti", "affiliation": { "@type": "Organization", "name": "Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, USA. Electronic address: gdotti@med.unc.edu." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "What are the Factors that Impact the Outcomes of Arthroscopic Rotator Cuff Repair?", "datePublished": "2024-04-29", "url": "https://questionsmedicales.fr/article/38679771", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.4103/njcp.njcp_706_23" } }, { "@type": "ScholarlyArticle", "name": "Rotator cuff muscle imbalance associates with shoulder instability direction.", "datePublished": "2022-08-09", "url": "https://questionsmedicales.fr/article/35961497", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.jse.2022.06.022" } }, { "@type": "ScholarlyArticle", "name": "Subacromial Balloon Spacers for Massive Irreparable Rotator Cuff Tears.", "datePublished": "2023-07-05", "url": "https://questionsmedicales.fr/article/37368826", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": null } }, { "@type": "ScholarlyArticle", "name": "The statistical fragility of studies on rotator cuff repair with graft augmentation.", "datePublished": "2023-01-18", "url": "https://questionsmedicales.fr/article/36681109", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.jse.2022.12.017" } }, { "@type": "ScholarlyArticle", "name": "Risk factors of radiographic severity of massive rotator cuff tear.", "datePublished": "2022-08-09", "url": "https://questionsmedicales.fr/article/35945235", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1038/s41598-022-17624-y" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Facteurs biologiques", "item": "https://questionsmedicales.fr/mesh/D001685" }, { "@type": "ListItem", "position": 3, "name": "Protéines et peptides de signalisation intercellulaire", "item": "https://questionsmedicales.fr/mesh/D036341" }, { "@type": "ListItem", "position": 4, "name": "Antigènes B7", "item": "https://questionsmedicales.fr/mesh/D060887" }, { "@type": "ListItem", "position": 5, "name": "Antigène CD274", "item": "https://questionsmedicales.fr/mesh/D060890" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Antigène CD274 - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Antigène CD274", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-09", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Antigène CD274", "description": "Comment diagnostiquer une expression anormale de CD274 ?\nQuels tests sanguins sont utilisés pour CD274 ?\nCD274 est-il associé à des biomarqueurs spécifiques ?\nQuels types de cancers montrent une surexpression de CD274 ?\nComment évaluer l'impact de CD274 sur le système immunitaire ?", "url": "https://questionsmedicales.fr/mesh/D060890?mesh_terms=Rotator+Cuff+Injuries&page=5#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Antigène CD274", "description": "Quels symptômes sont liés à une surexpression de CD274 ?\nCD274 influence-t-il les symptômes des maladies auto-immunes ?\nY a-t-il des symptômes spécifiques au cancer liés à CD274 ?\nComment CD274 affecte-t-il la réponse aux infections ?\nLes symptômes de CD274 sont-ils visibles cliniquement ?", "url": "https://questionsmedicales.fr/mesh/D060890?mesh_terms=Rotator+Cuff+Injuries&page=5#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Antigène CD274", "description": "Peut-on prévenir l'expression de CD274 ?\nComment un mode de vie sain influence-t-il CD274 ?\nY a-t-il des vaccins ciblant CD274 ?\nLa détection précoce des cancers aide-t-elle à gérer CD274 ?\nLes habitudes alimentaires influencent-elles CD274 ?", "url": "https://questionsmedicales.fr/mesh/D060890?mesh_terms=Rotator+Cuff+Injuries&page=5#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Antigène CD274", "description": "Quels traitements ciblent CD274 ?\nComment les thérapies immunologiques agissent-elles sur CD274 ?\nCD274 peut-il être une cible pour la thérapie génique ?\nQuels effets secondaires sont associés aux traitements ciblant CD274 ?\nLes traitements de CD274 sont-ils efficaces pour tous les cancers ?", "url": "https://questionsmedicales.fr/mesh/D060890?mesh_terms=Rotator+Cuff+Injuries&page=5#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Antigène CD274", "description": "Quelles complications sont liées à une surexpression de CD274 ?\nCD274 peut-il aggraver des maladies existantes ?\nY a-t-il des risques de résistance aux traitements avec CD274 ?\nComment CD274 influence-t-il la survie des patients ?\nLes complications de CD274 sont-elles réversibles ?", "url": "https://questionsmedicales.fr/mesh/D060890?mesh_terms=Rotator+Cuff+Injuries&page=5#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Antigène CD274", "description": "Quels facteurs augmentent le risque d'expression de CD274 ?\nLe tabagisme influence-t-il CD274 ?\nY a-t-il un lien entre l'obésité et CD274 ?\nLes infections virales affectent-elles CD274 ?\nLe stress chronique influence-t-il CD274 ?", "url": "https://questionsmedicales.fr/mesh/D060890?mesh_terms=Rotator+Cuff+Injuries&page=5#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une expression anormale de CD274 ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests immunohistochimiques peuvent être utilisés pour détecter CD274 dans les tissus." } }, { "@type": "Question", "name": "Quels tests sanguins sont utilisés pour CD274 ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des dosages de cytokines et des tests de surface cellulaire peuvent évaluer CD274." } }, { "@type": "Question", "name": "CD274 est-il associé à des biomarqueurs spécifiques ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, CD274 est souvent associé à des biomarqueurs de cancer comme PD-1." } }, { "@type": "Question", "name": "Quels types de cancers montrent une surexpression de CD274 ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Les cancers du poumon, du sein et de la vessie montrent souvent une surexpression de CD274." } }, { "@type": "Question", "name": "Comment évaluer l'impact de CD274 sur le système immunitaire ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Des études fonctionnelles sur les lymphocytes T peuvent évaluer l'impact de CD274." } }, { "@type": "Question", "name": "Quels symptômes sont liés à une surexpression de CD274 ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Une surexpression de CD274 peut entraîner une immunosuppression et des infections fréquentes." } }, { "@type": "Question", "name": "CD274 influence-t-il les symptômes des maladies auto-immunes ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, CD274 peut exacerber les symptômes des maladies auto-immunes en inhibant les cellules T." } }, { "@type": "Question", "name": "Y a-t-il des symptômes spécifiques au cancer liés à CD274 ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes peuvent inclure la fatigue, la perte de poids et des douleurs localisées." } }, { "@type": "Question", "name": "Comment CD274 affecte-t-il la réponse aux infections ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Une expression élevée de CD274 peut réduire l'efficacité de la réponse immunitaire aux infections." } }, { "@type": "Question", "name": "Les symptômes de CD274 sont-ils visibles cliniquement ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Non, CD274 n'a pas de symptômes visibles, mais son impact est observé par des tests." } }, { "@type": "Question", "name": "Peut-on prévenir l'expression de CD274 ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Il n'existe pas de méthode spécifique pour prévenir l'expression de CD274." } }, { "@type": "Question", "name": "Comment un mode de vie sain influence-t-il CD274 ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Un mode de vie sain peut renforcer le système immunitaire, potentiellement régulant CD274." } }, { "@type": "Question", "name": "Y a-t-il des vaccins ciblant CD274 ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Actuellement, il n'existe pas de vaccins spécifiquement ciblant CD274." } }, { "@type": "Question", "name": "La détection précoce des cancers aide-t-elle à gérer CD274 ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la détection précoce peut permettre une intervention rapide sur l'expression de CD274." } }, { "@type": "Question", "name": "Les habitudes alimentaires influencent-elles CD274 ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Certaines études suggèrent que l'alimentation peut moduler l'expression de CD274." } }, { "@type": "Question", "name": "Quels traitements ciblent CD274 ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les inhibiteurs de PD-1 et PD-L1, comme le pembrolizumab, ciblent CD274." } }, { "@type": "Question", "name": "Comment les thérapies immunologiques agissent-elles sur CD274 ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Elles bloquent l'interaction entre CD274 et PD-1, stimulant ainsi la réponse immunitaire." } }, { "@type": "Question", "name": "CD274 peut-il être une cible pour la thérapie génique ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Des recherches explorent la thérapie génique pour moduler l'expression de CD274." } }, { "@type": "Question", "name": "Quels effets secondaires sont associés aux traitements ciblant CD274 ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Les effets secondaires peuvent inclure des réactions auto-immunes et des inflammations." } }, { "@type": "Question", "name": "Les traitements de CD274 sont-ils efficaces pour tous les cancers ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Non, l'efficacité varie selon le type de cancer et le profil immunitaire du patient." } }, { "@type": "Question", "name": "Quelles complications sont liées à une surexpression de CD274 ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent une immunosuppression accrue et une progression tumorale." } }, { "@type": "Question", "name": "CD274 peut-il aggraver des maladies existantes ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, CD274 peut aggraver des maladies auto-immunes et des infections chroniques." } }, { "@type": "Question", "name": "Y a-t-il des risques de résistance aux traitements avec CD274 ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la surexpression de CD274 peut entraîner une résistance aux thérapies immunologiques." } }, { "@type": "Question", "name": "Comment CD274 influence-t-il la survie des patients ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Une expression élevée de CD274 est souvent associée à un pronostic défavorable dans le cancer." } }, { "@type": "Question", "name": "Les complications de CD274 sont-elles réversibles ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être réversibles avec un traitement approprié." } }, { "@type": "Question", "name": "Quels facteurs augmentent le risque d'expression de CD274 ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des antécédents de cancer, des infections chroniques et l'âge." } }, { "@type": "Question", "name": "Le tabagisme influence-t-il CD274 ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le tabagisme peut augmenter l'expression de CD274, surtout dans le cancer du poumon." } }, { "@type": "Question", "name": "Y a-t-il un lien entre l'obésité et CD274 ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Des études montrent que l'obésité peut être associée à une expression accrue de CD274." } }, { "@type": "Question", "name": "Les infections virales affectent-elles CD274 ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines infections virales peuvent induire l'expression de CD274 dans les cellules immunitaires." } }, { "@type": "Question", "name": "Le stress chronique influence-t-il CD274 ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Le stress chronique peut moduler l'expression de CD274, affectant la réponse immunitaire." } } ] } ] }

Sources (10000 au total)

What are the Factors that Impact the Outcomes of Arthroscopic Rotator Cuff Repair?

The cuff is a complex structure with many factors affecting it. How much it is affected after repair is still being investigated.... The aim of this study was to analyze the functional results of individuals who received arthroscopic rotator cuff repair and assess the various factors that could impact these outcomes.... The study included 57 patients with a mean age of 58.8 years (range: 39-71) who underwent arthroscopic rotator cuff repair between 2013 and 2020, with a minimum of 6 months after the operation. Functi... The effect of the operation on the scores in rotator cuff tears was highly significant (P < 0.05). Age, gender, tear size, fatty degeneration, anchor configuration, comorbidities, and additional proce... The results of rotator cuff repair appear to be influenced by several factors, including the sex of the patient, type and duration of tear, comorbidities, and surgical procedures used. Although these ...

Rotator cuff muscle imbalance associates with shoulder instability direction.

Although muscle weakness and/or imbalance of the rotator cuff are thought to contribute to the development of shoulder instability, the association between muscular dysfunction and shoulder instabilit... Preoperative magnetic resonance images of patients with shoulder instability who subsequently underwent arthroscopic glenohumeral labral repair or capsular plication were evaluated. Shoulder instabili... A total of 189 patients were included, where each group consisted of 63 patients. The infraspinatus + teres minor muscle area was smaller than the subscapularis muscle area in the anterior instability... Patients with anterior instability have smaller muscle area of the posterior rotator cuff as compared with the anterior rotator cuff. In contrast, patients with posterior instability and MDI have smal...

The statistical fragility of studies on rotator cuff repair with graft augmentation.

Clinical decision-making often relies on evidence-based medicine. Our purpose was to determine the fragility index (FI) and fragility quotient (FQ) for studies evaluating rotator cuff repair (RCR) wit... We performed a systematic review using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines by searching PubMed, the Cochrane library, and Embase in June 2022 to identify stud... The included studies had a total of 1098 patients with 36 dichotomous outcomes. The associated median FI was 4 (interquartile range 2-5), indicating that the reversal of 4 patients' outcomes would hav... Studies of RCR with graft augmentation lack statistical stability, with few altered outcome events required to reverse statistical significance. Larger comparative studies with better follow-up will s...

Collagen and platelet-rich plasma in partial-thickness rotator cuff injuries. Friends or only indifferent neighbours? Randomised controlled trial.

Partial-thickness rotator cuff injuries (PTRCI) are the sum of degenerative, overload, and microtrauma processes. An external supply of collagen and platelet-rich plasma (PRP) could potentially counte... Ninety patients with PTRCI were randomised and treated with ultrasound-guided injections into the shoulder bursa every consecutive week: Group A - collagen with PRP (n = 30), Group B - collagen alone ... No statistical differences were found between groups in primary outcomes, although there was a trend towards improvement in Groups A and C (opposite to Group B) between T2 and T3. The following parame... Combined therapy of collagen and PRP in PTRCI presents similar effectiveness to monotherapies with collagen or PRP.... The study was prospectively registered on the NCT Trial Center (identification number: NCT04492748 ) on 30.07.2020....

Clinical and Radiological Outcomes of Arthroscopic Superior Capsular Reconstruction Versus Primary Rotator Cuff Repair in Massive Rotator Cuff Tears: A Propensity Score-Matched Study.

Arthroscopic superior capsular reconstruction (aSCR) has emerged as a treatment option for managing massive rotator cuff tears (MRCTs) given the unpredictable results after an arthroscopic rotator cuf... To compare the clinical and radiological outcomes between aRCR and aSCR in patients with MRCT.... Cohort study; Level of evidence, 3.... A total of 163 cases of MRCT from 2010 to 2020 with follow-up ≥2 years were retrospectively reviewed. Among them, 102 had aRCR and 61 had aSCR using fascia lata autograft. Propensity score matching wa... Postoperative clinical outcomes were significantly improved at the final follow-up in both groups. In the aSCR group, postoperative forward flexion, pVAS, and AHD were significantly improved as compar... aSCR and aRCR are effective and reliable treatment options for MRCT. However, when compared with aRCR, aSCR showed improved clinical outcomes, including pVAS score, postoperative ROM, and favorable ra...

The robustness of glenohumeral centering measurements in dependence of shoulder rotation and their predictive value in shoulders with rotator cuff tears.

De-centering of the shoulder joint on radiographs is used as indicator for severity of rotator cuff tears and as predictor for clinical outcome after surgery. The objective of the study was to assess ... In this retrospective study (2014-2018), 249 shoulders were included: 92 with imaging-confirmed supra- and infraspinatus tears (rupture; 65.2 ± 9.9 years) and 157 without tears (control; 41.1 ± 13.0 y... In both positions, only the distance parameters ACHD (< 0.5 mm) and Deutsch (< 1 mm) were comparable in the two study groups rupture and control. Comparing the parameters between the study groups reve... Glenohumeral centering assessed by ACHD and Deutsch is not affected by rotation in shoulders with and without rotator cuff tear. An ACHD ≤ 6 mm has a positive predictive value of 90% for a massive rot...

Clinical outcomes and direct cost analysis of rotator cuff repair surgery.

The purpose of this study was to evaluate the clinical and functional outcomes in patients who underwent surgical treatment for rotator cuff tears using open and arthroscopic techniques, and to evalua... Retrospective cohort study with analysis of the data of patients who were referred to two private hospitals in Sao Paulo, Brazil for surgical repair of the rotator cuff from January 2018 to September ... Data from 362 patients were analyzed. The mean patient age was 57 years (SD= 10.46), with a slight male predominance (53.9%). Arthroscopic procedures were more common than open procedures (95.6% versu... Rotator cuff repair surgery is a highly effective procedure, associated with favorable clinical outcomes and improvement in life quality, and low rates of complications. Arthroscopic surgery tends to ...

Deep Learning Diagnosis and Classification of Rotator Cuff Tears on Shoulder MRI.

Detection of rotator cuff tears, a common cause of shoulder disability, can be time-consuming and subject to reader variability. Deep learning (DL) has the potential to increase radiologist accuracy a... The aim of this study was to develop a prototype DL model for detection and classification of rotator cuff tears on shoulder magnetic resonance imaging into no tear, partial-thickness tear, or full-th... This Health Insurance Portability and Accountability Act-compliant, institutional review board-approved study included a total of 11,925 noncontrast shoulder magnetic resonance imaging scans from 2 in... The AUC overall for supraspinatus, infraspinatus, and subscapularis tendon tears was 0.93, 0.89, and 0.90, respectively. The model performed best for full-thickness supraspinatus, infraspinatus, and s... Deep learning diagnosis of rotator cuff tears is feasible with excellent diagnostic performance, particularly for full-thickness tears, with model accuracy similar to subspecialty-trained musculoskele...