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"description": "Comment l'optogénétique est-elle diagnostiquée ?\nQuels outils sont utilisés pour le diagnostic ?\nPeut-on diagnostiquer des troubles avec l'optogénétique ?\nL'optogénétique nécessite-t-elle des échantillons biologiques ?\nQuels types de cellules sont ciblées en optogénétique ?",
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"description": "L'optogénétique est-elle utilisée comme traitement ?\nQuels types de maladies pourraient bénéficier de l'optogénétique ?\nComment l'optogénétique est-elle administrée ?\nQuels sont les résultats attendus des traitements optogénétiques ?\nY a-t-il des effets secondaires connus ?",
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"description": "Quelles complications peuvent survenir avec l'optogénétique ?\nY a-t-il des risques associés à l'optogénétique ?\nComment minimiser les complications en optogénétique ?\nLes complications sont-elles fréquentes ?\nQuelles sont les complications à long terme ?",
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"description": "Quels sont les facteurs de risque pour l'optogénétique ?\nL'âge influence-t-il les résultats de l'optogénétique ?\nY a-t-il des facteurs environnementaux à considérer ?\nLes facteurs génétiques jouent-ils un rôle ?\nComment évaluer les facteurs de risque en optogénétique ?",
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"@type": "Question",
"name": "Comment l'optogénétique est-elle diagnostiquée ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est diagnostiquée par des techniques d'imagerie et des tests fonctionnels sur des cellules modifiées."
}
},
{
"@type": "Question",
"name": "Quels outils sont utilisés pour le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des microscopes à fluorescence et des systèmes de stimulation lumineuse sont utilisés."
}
},
{
"@type": "Question",
"name": "Peut-on diagnostiquer des troubles avec l'optogénétique ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle aide à étudier des troubles neurologiques en ciblant des neurones spécifiques."
}
},
{
"@type": "Question",
"name": "L'optogénétique nécessite-t-elle des échantillons biologiques ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des échantillons de tissus ou de cellules sont souvent nécessaires pour l'analyse."
}
},
{
"@type": "Question",
"name": "Quels types de cellules sont ciblées en optogénétique ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Principalement des neurones, mais aussi d'autres types cellulaires peuvent être modifiés."
}
},
{
"@type": "Question",
"name": "Quels symptômes l'optogénétique peut-elle aider à étudier ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle aide à étudier des symptômes comme l'anxiété, la dépression et les troubles moteurs."
}
},
{
"@type": "Question",
"name": "L'optogénétique peut-elle induire des symptômes ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, elle ne provoque pas de symptômes, mais elle permet d'observer des réponses neuronales."
}
},
{
"@type": "Question",
"name": "Comment l'optogénétique aide-t-elle à comprendre les symptômes ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet de manipuler des circuits neuronaux pour observer les effets sur le comportement."
}
},
{
"@type": "Question",
"name": "Peut-on mesurer des symptômes en temps réel ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'optogénétique permet des mesures en temps réel des réponses neuronales aux stimuli."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont liés aux troubles traités par l'optogénétique ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme les convulsions, les troubles de l'humeur et les déficits cognitifs."
}
},
{
"@type": "Question",
"name": "L'optogénétique peut-elle aider à prévenir des maladies ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Indirectement, en permettant une meilleure compréhension des mécanismes de la maladie."
}
},
{
"@type": "Question",
"name": "Comment l'optogénétique contribue-t-elle à la recherche préventive ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet d'étudier les facteurs de risque et les mécanismes sous-jacents des maladies."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser l'optogénétique pour des études épidémiologiques ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut être intégrée dans des études pour comprendre la propagation des maladies."
}
},
{
"@type": "Question",
"name": "Quels types de prévention sont envisagés avec l'optogénétique ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des stratégies de prévention basées sur la modulation des circuits neuronaux."
}
},
{
"@type": "Question",
"name": "L'optogénétique peut-elle aider à identifier des biomarqueurs ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut aider à identifier des biomarqueurs pour des maladies neurologiques."
}
},
{
"@type": "Question",
"name": "L'optogénétique est-elle utilisée comme traitement ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est principalement utilisée pour la recherche, mais a un potentiel thérapeutique."
}
},
{
"@type": "Question",
"name": "Quels types de maladies pourraient bénéficier de l'optogénétique ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des maladies comme la maladie de Parkinson, l'épilepsie et les troubles de l'humeur."
}
},
{
"@type": "Question",
"name": "Comment l'optogénétique est-elle administrée ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est administrée par l'insertion de gènes sensibles à la lumière dans des cellules cibles."
}
},
{
"@type": "Question",
"name": "Quels sont les résultats attendus des traitements optogénétiques ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Amélioration des symptômes neurologiques et modulation des circuits neuronaux."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires connus ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les effets secondaires sont encore à l'étude, mais peuvent inclure des réponses immunitaires."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec l'optogénétique ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications peuvent inclure des infections ou des réactions aux vecteurs utilisés."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques associés à l'optogénétique ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les risques incluent des effets indésirables liés à la manipulation génétique."
}
},
{
"@type": "Question",
"name": "Comment minimiser les complications en optogénétique ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "En suivant des protocoles stricts et en surveillant les patients après les interventions."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles fréquentes ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles sont rares, mais la recherche continue d'évaluer la sécurité de la technique."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications à long terme ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications à long terme sont encore mal comprises et nécessitent des études approfondies."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour l'optogénétique ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents médicaux, des maladies neurologiques et des traitements antérieurs."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il les résultats de l'optogénétique ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'âge peut affecter la réponse aux traitements optogénétiques et la récupération."
}
},
{
"@type": "Question",
"name": "Y a-t-il des facteurs environnementaux à considérer ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des facteurs comme le stress et l'exposition à des toxines peuvent influencer les résultats."
}
},
{
"@type": "Question",
"name": "Les facteurs génétiques jouent-ils un rôle ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les variations génétiques peuvent influencer la réponse aux interventions optogénétiques."
}
},
{
"@type": "Question",
"name": "Comment évaluer les facteurs de risque en optogénétique ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Par des évaluations cliniques et des études génétiques pour identifier les vulnérabilités."
}
}
]
}
]
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This study aimed to compare the effectiveness of the modified Bass technique (MBT), the Rolling technique and the current brushing technique(CBT) for plaque removal and to assess the acceptability of ...
180 participants were randomly assigned to PowerPoint-based training with a demonstration of either the MBT plus basic toothbrushing, the Rolling technique plus basic toothbrushing, or the basics of t...
After instruction (0 weeks), all groups showed a significant decrease in TQHI and MPI (p<0.001), followed by a gradual increase. There was no difference in the overall effect of plaque removal between...
There was no difference in the overall plaque removal effect among the three groups. The MBT was most effective in removing plaque at the cervical margin but more difficult to master....
This study was conducted to compare the teaching and plaque removal effects of two brushing techniques and to understand which method is better for plaque removal as well as adoption. This study provi...
Despite contributing to a reduction in dental caries, improper use of fluoridated toothpaste could add to the burden of dental fluorosis in children....
To assess the association between tooth-brushing practices such as the type and amount of toothpaste used, frequency of tooth brushing, parental assistance in tooth brushing, timing of tooth brushing ...
For this case-control study, a sex-matched sample of 15-year-old school children attending government schools in Kurunegala district and who were lifetime residents of the district was selected. Denta...
Tooth brushing ≥ twice/day, brushing after breakfast and parent/care giver brushing the child's teeth reduced the likelihood of developing fluorosis....
Use of fluoridated toothpaste adhering to the recommended guidelines could prevent dental fluorosis in children in this endemic area....
To compare the cleansing efficacy of an auto-cleaning device with nylon bristles (Y-brush®) to that of manual toothbrushing....
Twenty probands refrained from oral hygiene for 3 days. Rustogi Modified Navy Plaque Index was assessed before and after (randomized) toothbrushing either with the auto-cleaning device for 5 s per jaw...
Full-mouth plaque reduction was higher with manual toothbrushing than with auto-cleaning for 5 s per jaw (p < 0.001). There was no statistically significant difference on smooth tooth surfaces but on ...
Auto-cleaning devices with nylon bristles have a future potential to reach plaque reduction levels comparable to manual toothbrushing, although manufacturers must focus on improving an accurate fit....
Under the premise of an ameliorated fit, the auto-cleaning device might be recommendable for people with low brushing efficacy. Interdental sites remain a failure point if adjunct interdental cleaning...
The meaning of the toothbrushing technique for the effectivity of toothbrushing in terms of plaque removal and parameters of gingivitis is unknown. This systematic review and network meta-analysis (NM...
We searched MEDLINE (PubMed), the Cochrane Central Register of Controlled Trials, and the Web of Science for RCTs that compared any self-applied manual toothbrushing technique to any other technique o...
Thirteen publications, including 15 studies, were identified. Ten studies assessing the Fones, Bass, and Scrub techniques provided data eligible for the NMA. The confidence rating of the evidence vari...
There is limited evidence regarding the effects of toothbrushing techniques on plaque after brushing or gingivitis....
The aim of this study was to evaluate the effectiveness of Mozart's music on the learning of toothbrushing behavior in children with high and low dental anxiety levels....
A randomized, controlled, single-blinded, and observational study was conducted with 60 children, aged 8-12, who were recruited to high dental anxiety level (HDAL) and low dental anxiety level (LDAL) ...
There was a statistically significant decrease in plaque index (PI) and gingival index (GI) scores in the follow-up visits for all groups (p < 0.05). A statistically significant decrease was found in ...
Listening to Mozart's music before toothbrushing training had a significant effect on plaque removal in children with high dental anxiety, while Mozart's music did not have a positive effect in the gr...
The use of Mozart's music may be beneficial in oral hygiene education for children with high dental anxiety levels....
The aim of this study was to evaluate toothbrush hygienic practices, whether subjects with a positive COVID-19 test received instructions about toothbrush hygiene, and to determine if carriers of SARS...
Data were collected by an anonymous online questionnaire. Variables of interest included toothbrush hygiene practices, receiving instructions on toothbrush handling if tested positive for COVID-19, an...
From November 2020 through April 2021; 755 responded (472 [62.5%] females, 269 [35.6%] males, 14 [1.85%] did not specify their gender). 14 (4.1%) of 341 respondents who reported a positive result of a...
The majority of participants with a positive result of the COVID-19 test were not given explicit instructions about toothbrush handling. Less than half reported good toothbrush hygienic practices. Hig...
Crown restorations in anterior region are recommended highly color-reproductivity because of aesthetic reason. Composite resin block with several shade gradations is especially produced for anterior r...
Introduction A recent resurgence of sustainability in healthcare has resulted in huge progress towards more 'eco-aware' products and their incorporation into everyday life, with home oral hygiene prod...
Background and Objectives: The aim of this in vitro study was to evaluate the effect of simulated gastric acid associated with toothbrushing on the surface condition of three resin-modified glass-iono...
The use of toothbrushes was investigated as a potential RNA source and gene expression profiling tool for oral cancer screening in tobacco and alcohol users....
A total of 20 subjects were selected on the basis of inclusion and exclusion criteria. They were divided into two groups: group I-healthy controls (...
The gene expression of BAX decreased significantly in alcoholics and smokers (0.13867 ± 0.12014), while the gene expression of BCL2 increased in alcoholics and smokers (1.91001 ± 0.90425) in compariso...
A toothbrush is a good source of RNA, and gene expression analysis can be performed using the genetic material retrieved from toothbrushes, which can aid in the early diagnosis of oral squamous cell c...