Titre : Optogénétique

Optogénétique : Questions médicales fréquentes

Termes MeSH sélectionnés :

Toothbrushing
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troubles avec l'optogénétique ?\nL'optogénétique nécessite-t-elle des échantillons biologiques ?\nQuels types de cellules sont ciblées en optogénétique ?", "url": "https://questionsmedicales.fr/mesh/D062308?mesh_terms=Toothbrushing&page=6#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Optogénétique", "description": "Quels symptômes l'optogénétique peut-elle aider à étudier ?\nL'optogénétique peut-elle induire des symptômes ?\nComment l'optogénétique aide-t-elle à comprendre les symptômes ?\nPeut-on mesurer des symptômes en temps réel ?\nQuels symptômes sont liés aux troubles traités par l'optogénétique ?", "url": "https://questionsmedicales.fr/mesh/D062308?mesh_terms=Toothbrushing&page=6#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Optogénétique", "description": "L'optogénétique peut-elle aider à prévenir des maladies ?\nComment l'optogénétique contribue-t-elle à la recherche préventive ?\nPeut-on utiliser l'optogénétique pour des études épidémiologiques ?\nQuels types de prévention sont envisagés avec l'optogénétique ?\nL'optogénétique peut-elle aider à identifier des biomarqueurs ?", "url": "https://questionsmedicales.fr/mesh/D062308?mesh_terms=Toothbrushing&page=6#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Optogénétique", "description": "L'optogénétique est-elle utilisée comme traitement ?\nQuels types de maladies pourraient bénéficier de l'optogénétique ?\nComment l'optogénétique est-elle administrée ?\nQuels sont les résultats attendus des traitements optogénétiques ?\nY a-t-il des effets secondaires connus ?", "url": "https://questionsmedicales.fr/mesh/D062308?mesh_terms=Toothbrushing&page=6#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Optogénétique", "description": "Quelles complications peuvent survenir avec l'optogénétique ?\nY a-t-il des risques associés à l'optogénétique ?\nComment minimiser les complications en optogénétique ?\nLes complications sont-elles fréquentes ?\nQuelles sont les complications à long terme ?", "url": "https://questionsmedicales.fr/mesh/D062308?mesh_terms=Toothbrushing&page=6#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Optogénétique", "description": "Quels sont les facteurs de risque pour l'optogénétique ?\nL'âge influence-t-il les résultats de l'optogénétique ?\nY a-t-il des facteurs environnementaux à considérer ?\nLes facteurs génétiques jouent-ils un rôle ?\nComment évaluer les facteurs de risque en optogénétique ?", "url": "https://questionsmedicales.fr/mesh/D062308?mesh_terms=Toothbrushing&page=6#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment l'optogénétique est-elle diagnostiquée ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Elle est diagnostiquée par des techniques d'imagerie et des tests fonctionnels sur des cellules modifiées." } }, { "@type": "Question", "name": "Quels outils sont utilisés pour le diagnostic ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des microscopes à fluorescence et des systèmes de stimulation lumineuse sont utilisés." } }, { "@type": "Question", "name": "Peut-on diagnostiquer des troubles avec l'optogénétique ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle aide à étudier des troubles neurologiques en ciblant des neurones spécifiques." } }, { "@type": "Question", "name": "L'optogénétique nécessite-t-elle des échantillons biologiques ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des échantillons de tissus ou de cellules sont souvent nécessaires pour l'analyse." } }, { "@type": "Question", "name": "Quels types de cellules sont ciblées en optogénétique ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Principalement des neurones, mais aussi d'autres types cellulaires peuvent être modifiés." } }, { "@type": "Question", "name": "Quels symptômes l'optogénétique peut-elle aider à étudier ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Elle aide à étudier des symptômes comme l'anxiété, la dépression et les troubles moteurs." } }, { "@type": "Question", "name": "L'optogénétique peut-elle induire des symptômes ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Non, elle ne provoque pas de symptômes, mais elle permet d'observer des réponses neuronales." } }, { "@type": "Question", "name": "Comment l'optogénétique aide-t-elle à comprendre les symptômes ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Elle permet de manipuler des circuits neuronaux pour observer les effets sur le comportement." } }, { "@type": "Question", "name": "Peut-on mesurer des symptômes en temps réel ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'optogénétique permet des mesures en temps réel des réponses neuronales aux stimuli." } }, { "@type": "Question", "name": "Quels symptômes sont liés aux troubles traités par l'optogénétique ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes comme les convulsions, les troubles de l'humeur et les déficits cognitifs." } }, { "@type": "Question", "name": "L'optogénétique peut-elle aider à prévenir des maladies ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Indirectement, en permettant une meilleure compréhension des mécanismes de la maladie." } }, { "@type": "Question", "name": "Comment l'optogénétique contribue-t-elle à la recherche préventive ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Elle permet d'étudier les facteurs de risque et les mécanismes sous-jacents des maladies." } }, { "@type": "Question", "name": "Peut-on utiliser l'optogénétique pour des études épidémiologiques ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle peut être intégrée dans des études pour comprendre la propagation des maladies." } }, { "@type": "Question", "name": "Quels types de prévention sont envisagés avec l'optogénétique ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Des stratégies de prévention basées sur la modulation des circuits neuronaux." } }, { "@type": "Question", "name": "L'optogénétique peut-elle aider à identifier des biomarqueurs ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle peut aider à identifier des biomarqueurs pour des maladies neurologiques." } }, { "@type": "Question", "name": "L'optogénétique est-elle utilisée comme traitement ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Elle est principalement utilisée pour la recherche, mais a un potentiel thérapeutique." } }, { "@type": "Question", "name": "Quels types de maladies pourraient bénéficier de l'optogénétique ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Des maladies comme la maladie de Parkinson, l'épilepsie et les troubles de l'humeur." } }, { "@type": "Question", "name": "Comment l'optogénétique est-elle administrée ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Elle est administrée par l'insertion de gènes sensibles à la lumière dans des cellules cibles." } }, { "@type": "Question", "name": "Quels sont les résultats attendus des traitements optogénétiques ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Amélioration des symptômes neurologiques et modulation des circuits neuronaux." } }, { "@type": "Question", "name": "Y a-t-il des effets secondaires connus ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Les effets secondaires sont encore à l'étude, mais peuvent inclure des réponses immunitaires." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec l'optogénétique ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications peuvent inclure des infections ou des réactions aux vecteurs utilisés." } }, { "@type": "Question", "name": "Y a-t-il des risques associés à l'optogénétique ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Les risques incluent des effets indésirables liés à la manipulation génétique." } }, { "@type": "Question", "name": "Comment minimiser les complications en optogénétique ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "En suivant des protocoles stricts et en surveillant les patients après les interventions." } }, { "@type": "Question", "name": "Les complications sont-elles fréquentes ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Elles sont rares, mais la recherche continue d'évaluer la sécurité de la technique." } }, { "@type": "Question", "name": "Quelles sont les complications à long terme ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Les complications à long terme sont encore mal comprises et nécessitent des études approfondies." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour l'optogénétique ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des antécédents médicaux, des maladies neurologiques et des traitements antérieurs." } }, { "@type": "Question", "name": "L'âge influence-t-il les résultats de l'optogénétique ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'âge peut affecter la réponse aux traitements optogénétiques et la récupération." } }, { "@type": "Question", "name": "Y a-t-il des facteurs environnementaux à considérer ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des facteurs comme le stress et l'exposition à des toxines peuvent influencer les résultats." } }, { "@type": "Question", "name": "Les facteurs génétiques jouent-ils un rôle ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les variations génétiques peuvent influencer la réponse aux interventions optogénétiques." } }, { "@type": "Question", "name": "Comment évaluer les facteurs de risque en optogénétique ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Par des évaluations cliniques et des études génétiques pour identifier les vulnérabilités." } } ] } ] }

Sources (343 au total)

Assessing oral and toothbrush microbial profiles among high-altitude individuals with and without periodontal disease: a case-control study.

Periodontitis is the sixth-most common disease worldwide. The oral microbiome composition and its association with Periodontal disease (PD) have been largely explored; however, limited studies have ex... In the present study, we enrolled 35 individuals including 21 healthy and 14 diagnosed with PD from the Lhasa region of Tibet, China. Saliva and toothbrush samples were collected from each participant... Significantly higher Alpha diversity (Shannon index) was observed between the PD group and PD toothbrushes (p = 0.00021) and between the PD group and Healthy toothbrushes (p = 0.00041). The predominan... This study emphasizes the importance of tailored dental care strategies, accounting for altitude and racial factors, to effectively manage periodontal health in these communities. Further research is ...

Evaluation of plaque removal by a single-headed versus a triple-headed manual toothbrush using different plaque assessment tools.

Dental plaque is a common issue that can be effectively managed with proper oral hygiene practices and regular oral health care. The aim of this crossover study was to assess dental plaque using diffe... Plaque staining was performed to assess dental plaque amounts before and after brushing with the triple-headed (test) and single-headed (control) manual toothbrush in 21 study participants after plaqu... Toothbrushing with a manual single-headed toothbrush and a triple-headed toothbrush was found to be equally effective when comparing plaque removal ability. Brushing time was shorter when using a trip... The triple-headed manual toothbrush may be a good alternative to the single-headed manual toothbrush for certain patient groups....

Effects of gastric acid and mechanical toothbrushing in CAD-CAM restorative materials: Mechanical properties, surface topography, and biofilm adhesion.

To evaluate the effects of simulated gastric acid erosion combined with mechanical toothbrushing abrasion on the mechanical properties, surface topography, and biofilm adhesion of different CAD/CAM ma... Specimens of zirconia-reinforced lithium silicate glass-ceramic (ZLS), polymer-infiltrated ceramic network (PICN), feldspathic glass-ceramic (FE), and two nanoceramic resins (RK, RG), were submitted t... FE showed the lowest flexural strengths, while ZLS and RG exhibited the highest, while PICN and RK, had intermediate values. PICN, ZLS, and FE showed lower microhardness after E and E + A challenges t... Erosive challenges combined with abrasion negatively influenced the mechanical properties and surface topography of most CAD/CAM materials and increased the biofilm adhesion on ZLS. Besides, the sever...

Oral hygiene knowledge versus behavior in children: A questionnaire-based, interview-style analysis and on-site assessment of toothbrushing practices.

Oral hygiene plays an important role in eliminating biofilms and preventing dental caries. However, the implementation of oral health knowledge that children learn from their parents and through schoo... This was a questionnaire-based, interview-style community survey and on-site practical assessment of CYAs' toothbrushing skills conducted during two 1-day public science-promoting events held at a maj... Of 244 participating CYAs, 178 (73%) CYAs had no caries experience, the percentage increasing with age from 5% in 2-5-year-olds to 40% in those aged > 10 years. Of 117/244 (48%) indicating that teeth ... CYAs knew about the importance of oral hygiene and cleaned their teeth frequently. However, translation of their knowledge into practice showed deficiencies. Repeated encouragement to put oral health ...

"You should brush your teeth better": a randomized controlled trial comparing best-possible versus as-usual toothbrushing.

Most people's tooth brushing performance is deficient, even when they are encouraged to brush to the best of their abilities. The aim of the present study was to explore the nature of this deficit by ... University students (N = 111) were randomly assigned to receive one of two instructions: "brush your teeth as usual" (AU-instruction) or "brush your teeth to the best of your abilities" (BP-instructio... Participants in the BP group brushed their teeth longer (p = 0.008, d = 0.57) and used interdental devices more often (p < 0.001). No group differences emerged in the distribution of brushing time amo... Compared to their usual brushing effort, study participants increased their effort when asked to brush their teeth in the best possible manner. However, that increase in effort was ineffective in term... The study was registered in the appropriate national register ( www.drks.de ; ID: DRKS00017812; date of registration: 27/08/2019 - retrospectively registered)....

Socioeconomic inequalities in toothbrushing behaviours in young children: a children's lifestyle survey in a representative population of A city, Okinawa prefecture, Japan.

We have less understanding of which socioeconomic status (SES) indicators may be reflective of latent socioeconomic inequalities in toothbrushing behaviours, especially finishing-toothbrushing by pare... We used data from 'Survey on Children's Life' conducted by A city of Okinawa Prefecture, Japan. The multiple imputed data of 902 (boys, 453) included self-reported children's toothbrushing behaviour a... There were significant absolute and relative inequalities of children's toothbrushing for household income (SII and RII were 0.241 and 2.73, respectively), of finishing-toothbrushing by parents for ho... Socioeconomic inequalities in children's toothbrushing and finishing-toothbrushing by parents varied according to SES indicators....

HABIT: Health visitors delivering Advice in Britain on Infant Toothbrushing - an early-phase feasibility study of a complex oral health intervention.

To conduct an early-phase feasibility study of an oral health intervention, Health visitors delivering Advice on Britain on Infant Toothbrushing (HABIT), delivered by Health Visitors to parents of chi... A mixed-methods, early-phase, non-controlled, feasibility study.... Recruitment consisted of Group A-HABIT-trained Health Visitors (n=11) and Group B-parents of children aged 9-12 months old about to receive their universal health check (n=35).... Bradford, West Yorkshire, UK.... A multidisciplinary team co-developed digital and paper-based training resources with health visitors and parents of young children. The intervention comprised of two components: (A) training for heal... Recruitment, retention and intervention delivery were analysed as key process outcomes for Groups A and B. Group B demographics, self-reported toothbrushing behaviours, dietary habits and three object... HABIT intervention delivery was feasible. Although the intended sample size was recruited (Group A=11 and Group B=35) it was more challenging than anticipated. Retention of Group B participants to fin... This feasibility study has demonstrated that HABIT is an appropriate oral health intervention. Adaptions to the study design are recommended to maximise recruitment and data collection in a definitive... ISRCTN55332414....

Evaluation of knowledge about and attitudes towards toothbrush disinfection, personal plaque control, and periodontal diseases of patients presenting to dental clinics.

The present study aims to evaluate patients' knowledge about toothbrush disinfection (TBD), plaque control, knowledge, and awareness of periodontal diseases (P-knowledge and P-awareness).... The study enrolled 121 participants (70 women and 51 men). Participants were asked to fill out a survey containing questions about demographic characteristics, toothbrushing habits, toothbrush storage... The participants (51.2%) do not have any knowledge about TBD. Most of those who reported disinfecting their toothbrushes think that washing toothbrushes with tap water is disinfection (23.1%). One mon... The results of the study suggest that the participants do not have enough knowledge about toothbrush storage conditions, toothpaste sharing, and TBD. Collaborating with dental hygienists to raise awar...