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Acides aminés, peptides et protéines
Protéines
Nucléoprotéines
Protéines chromosomiques nonhistones
Protéines de maintenance des minichromosomes
Protéines de maintenance des minichromosomes : Questions médicales fréquentes
Termes MeSH sélectionnés :
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"name": "Comment diagnostiquer une anomalie des protéines MCM ?",
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"text": "Des tests génétiques et des analyses de protéines peuvent identifier des anomalies."
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"@type": "Question",
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"position": 4,
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"@type": "Question",
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"position": 6,
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"@type": "Question",
"name": "Les symptômes sont-ils spécifiques aux MCM ?",
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"@type": "Question",
"name": "Comment les MCM affectent-elles la santé cellulaire ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une mauvaise fonction des MCM peut entraîner des erreurs dans la réplication de l'ADN."
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"@type": "Question",
"name": "Les MCM sont-elles liées à des symptômes neurologiques ?",
"position": 9,
"acceptedAnswer": {
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"text": "Certaines études suggèrent un lien entre les MCM et des troubles neurologiques."
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"@type": "Question",
"name": "Peut-on observer des symptômes précoces de dysfonction MCM ?",
"position": 10,
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"text": "Oui, des signes précoces peuvent inclure des anomalies de croissance cellulaire."
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"@type": "Question",
"name": "Peut-on prévenir les anomalies des MCM ?",
"position": 11,
"acceptedAnswer": {
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"text": "Une bonne hygiène de vie et un suivi médical régulier peuvent aider à prévenir."
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"@type": "Question",
"name": "Y a-t-il des tests de dépistage pour les MCM ?",
"position": 12,
"acceptedAnswer": {
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"text": "Des tests génétiques peuvent être proposés pour les personnes à risque élevé."
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"@type": "Question",
"name": "L'alimentation influence-t-elle les MCM ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut soutenir la santé cellulaire et la fonction des MCM."
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"@type": "Question",
"name": "Le stress affecte-t-il les MCM ?",
"position": 14,
"acceptedAnswer": {
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"text": "Le stress chronique peut perturber la fonction cellulaire, y compris celle des MCM."
}
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"@type": "Question",
"name": "Les exercices physiques aident-ils les MCM ?",
"position": 15,
"acceptedAnswer": {
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"text": "Oui, l'exercice régulier peut améliorer la santé cellulaire et la fonction des MCM."
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"@type": "Question",
"name": "Quels traitements ciblent les MCM ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des inhibiteurs spécifiques de MCM sont en cours de développement pour le cancer."
}
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"@type": "Question",
"name": "Les thérapies géniques peuvent-elles aider ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la thérapie génique pourrait corriger les anomalies des MCM dans certains cas."
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"@type": "Question",
"name": "Y a-t-il des médicaments pour les MCM ?",
"position": 18,
"acceptedAnswer": {
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"text": "Des médicaments ciblant la voie de réplication de l'ADN sont en développement."
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"@type": "Question",
"name": "Comment la chimiothérapie affecte-t-elle les MCM ?",
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"@type": "Question",
"name": "Les traitements sont-ils personnalisés pour les MCM ?",
"position": 20,
"acceptedAnswer": {
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"text": "Oui, les traitements peuvent être adaptés en fonction des profils de MCM des patients."
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"@type": "Question",
"name": "Quelles complications peuvent survenir avec des anomalies MCM ?",
"position": 21,
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"text": "Des complications incluent des cancers, des troubles de croissance et des maladies génétiques."
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"@type": "Question",
"name": "Les anomalies MCM sont-elles héréditaires ?",
"position": 22,
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"@type": "Question",
"name": "Comment les MCM affectent-elles le vieillissement ?",
"position": 23,
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"@type": "Question",
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"@type": "Question",
"name": "Quels facteurs augmentent le risque d'anomalies MCM ?",
"position": 26,
"acceptedAnswer": {
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"text": "Des facteurs génétiques, environnementaux et liés au mode de vie peuvent augmenter le risque."
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"@type": "Question",
"name": "L'exposition à des toxines influence-t-elle les MCM ?",
"position": 27,
"acceptedAnswer": {
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"text": "Oui, l'exposition à certaines toxines peut perturber la fonction des MCM."
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"@type": "Question",
"name": "Le tabagisme affecte-t-il les MCM ?",
"position": 28,
"acceptedAnswer": {
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"text": "Le tabagisme est un facteur de risque connu pour des anomalies dans la fonction des MCM."
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"name": "Le vieillissement est-il un facteur de risque pour les MCM ?",
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"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de maladies liées aux MCM peuvent augmenter le risque."
}
}
]
}
]
}
Enzymatic reactions are an ecofriendly, selective, and versatile addition, sometimes even alternative to organic reactions for the synthesis of chemical compounds such as pharmaceuticals or fine chemi...
The emerging European Health Data Space (EHDS) Regulation opens new prospects for large-scale sharing and re-use of health data. Yet, the proposed regulation suffers from two important limitations: it...
Humans are exposed to large numbers of chemicals during their daily activities. To assess and understand potential health impacts of chemical exposure, investigators and regulators need access to reli...
Biodiversity data records contain inaccuracies and biases. To overcome this limitation and establish robust geographic patterns, ecologists often curate records keeping those that are most suitable fo...
An archive of 5 years of cases involving the identification of human remains was curated, collecting information on: The sample type submitted, the number of STR loci yielding interpretable results, t...
Data gaps and biases are two important issues that affect the quality of biodiversity information and downstream results. Understanding how best to fill existing gaps and account for biases is necessa...
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The growing threat of antimicrobial resistance (AMR) calls for new epidemiological surveillance methods, as well as a deeper understanding of how antimicrobial resistance genes (ARGs) have been transm...
Automated curation of noisy external data in the medical domain has long been in high demand, as AI technologies need to be validated using various sources with clean, annotated data. Identifying the ...
Generation of high-quality data sets of protein kinase inhibitors (PKIs)....
Publicly available PKIs with reliable activity data were curated. PKIs with very weak activity were classified as inactive. Analogue series and PKIs containing reactive groups (warheads) enabling cova...
A total of 155,579 human and 3057 mouse PKIs were obtained. Human PKIs were active 440 kinases and included 13,949 covalent PKIs. The collection of qualifying PKIs and corresponding inactive compounds...
Potential limitations include activity data incompleteness and assay variance. The data set can be used to investigate PKIs with alternative modes of action and calibrate computational methods....