Oui, l'âge avancé peut augmenter le risque d'anomalies chromosomiques.
ÂgeAnomalies chromosomiques
#3
Le mode de vie affecte-t-il le risque ?
Un mode de vie malsain peut augmenter le risque d'anomalies génétiques.
Mode de vieAnomalies génétiques
#4
Y a-t-il des antécédents familiaux à considérer ?
Oui, des antécédents familiaux d'anomalies peuvent augmenter le risque.
Antécédents familiauxRisque
#5
Les infections pendant la grossesse sont-elles un facteur de risque ?
Certaines infections pendant la grossesse peuvent affecter le développement chromosomique.
InfectionsGrossesse
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Composant-7 du complexe de maintenance des minichromosomes : Questions médicales les plus fréquentes",
"headline": "Composant-7 du complexe de maintenance des minichromosomes : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Composant-7 du complexe de maintenance des minichromosomes : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-07-23",
"dateModified": "2025-04-19",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Composant-7 du complexe de maintenance des minichromosomes"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Protéines de maintenance des minichromosomes",
"url": "https://questionsmedicales.fr/mesh/D064110",
"about": {
"@type": "MedicalCondition",
"name": "Protéines de maintenance des minichromosomes",
"code": {
"@type": "MedicalCode",
"code": "D064110",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D12.776.664.235.750"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Composant-7 du complexe de maintenance des minichromosomes",
"alternateName": "Minichromosome Maintenance Complex Component 7",
"code": {
"@type": "MedicalCode",
"code": "D064168",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Qing Yang",
"url": "https://questionsmedicales.fr/author/Qing%20Yang",
"affiliation": {
"@type": "Organization",
"name": "Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China."
}
},
{
"@type": "Person",
"name": "Binhui Xie",
"url": "https://questionsmedicales.fr/author/Binhui%20Xie",
"affiliation": {
"@type": "Organization",
"name": "Department of Hepatobiliary Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, China."
}
},
{
"@type": "Person",
"name": "Hui Tang",
"url": "https://questionsmedicales.fr/author/Hui%20Tang",
"affiliation": {
"@type": "Organization",
"name": "Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China."
}
},
{
"@type": "Person",
"name": "Wei Meng",
"url": "https://questionsmedicales.fr/author/Wei%20Meng",
"affiliation": {
"@type": "Organization",
"name": "Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China."
}
},
{
"@type": "Person",
"name": "Changchang Jia",
"url": "https://questionsmedicales.fr/author/Changchang%20Jia",
"affiliation": {
"@type": "Organization",
"name": "Cell-gene Therapy Translational Medicine Research Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Predictive Nature of High-Throughput Assays in ADC Formulation Screening.",
"datePublished": "2023-04-08",
"url": "https://questionsmedicales.fr/article/37037342",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.xphs.2023.03.021"
}
},
{
"@type": "ScholarlyArticle",
"name": "A simple protein histidine kinase activity assay for high-throughput inhibitor screening.",
"datePublished": "2022-11-02",
"url": "https://questionsmedicales.fr/article/36371819",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.bioorg.2022.106232"
}
},
{
"@type": "ScholarlyArticle",
"name": "A Novel Fluorescence-Based Microplate Assay for High-Throughput Screening of hSULT1As Inhibitors.",
"datePublished": "2024-05-27",
"url": "https://questionsmedicales.fr/article/38920579",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/bios14060275"
}
},
{
"@type": "ScholarlyArticle",
"name": "Assay establishment and validation of a high-throughput organoid-based drug screening platform.",
"datePublished": "2022-05-26",
"url": "https://questionsmedicales.fr/article/35619149",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1186/s13287-022-02902-3"
}
},
{
"@type": "ScholarlyArticle",
"name": "The colors of peroxygenase activity: Colorimetric high-throughput screening assays for directed evolution.",
"datePublished": "2023-10-16",
"url": "https://questionsmedicales.fr/article/37977739",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/bs.mie.2023.09.006"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Acides aminés, peptides et protéines",
"item": "https://questionsmedicales.fr/mesh/D000602"
},
{
"@type": "ListItem",
"position": 3,
"name": "Protéines",
"item": "https://questionsmedicales.fr/mesh/D011506"
},
{
"@type": "ListItem",
"position": 4,
"name": "Nucléoprotéines",
"item": "https://questionsmedicales.fr/mesh/D009698"
},
{
"@type": "ListItem",
"position": 5,
"name": "Protéines chromosomiques nonhistones",
"item": "https://questionsmedicales.fr/mesh/D002868"
},
{
"@type": "ListItem",
"position": 6,
"name": "Protéines de maintenance des minichromosomes",
"item": "https://questionsmedicales.fr/mesh/D064110"
},
{
"@type": "ListItem",
"position": 7,
"name": "Composant-7 du complexe de maintenance des minichromosomes",
"item": "https://questionsmedicales.fr/mesh/D064168"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Composant-7 du complexe de maintenance des minichromosomes - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Composant-7 du complexe de maintenance des minichromosomes",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-15",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Composant-7 du complexe de maintenance des minichromosomes",
"description": "Comment diagnostiquer une anomalie du Composant-7 ?\nQuels tests sont utilisés pour évaluer le Composant-7 ?\nY a-t-il des marqueurs spécifiques pour le Composant-7 ?\nLe diagnostic nécessite-t-il une biopsie ?\nQuels symptômes peuvent indiquer un problème avec le Composant-7 ?",
"url": "https://questionsmedicales.fr/mesh/D064168?mesh_terms=High-Throughput+Screening+Assays#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Composant-7 du complexe de maintenance des minichromosomes",
"description": "Quels sont les symptômes d'une défaillance du Composant-7 ?\nPeut-on observer des symptômes cliniques ?\nLes symptômes varient-ils selon les individus ?\nY a-t-il des signes précoces d'anomalies ?\nLes symptômes sont-ils réversibles ?",
"url": "https://questionsmedicales.fr/mesh/D064168?mesh_terms=High-Throughput+Screening+Assays#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Composant-7 du complexe de maintenance des minichromosomes",
"description": "Peut-on prévenir les anomalies du Composant-7 ?\nY a-t-il des facteurs environnementaux à éviter ?\nDes dépistages réguliers sont-ils recommandés ?\nL'alimentation joue-t-elle un rôle dans la prévention ?\nLes vaccinations peuvent-elles aider ?",
"url": "https://questionsmedicales.fr/mesh/D064168?mesh_terms=High-Throughput+Screening+Assays#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Composant-7 du complexe de maintenance des minichromosomes",
"description": "Quels traitements sont disponibles pour les anomalies du Composant-7 ?\nLa thérapie génique est-elle efficace ?\nDes médicaments spécifiques sont-ils utilisés ?\nLe traitement nécessite-t-il une surveillance régulière ?\nY a-t-il des effets secondaires aux traitements ?",
"url": "https://questionsmedicales.fr/mesh/D064168?mesh_terms=High-Throughput+Screening+Assays#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Composant-7 du complexe de maintenance des minichromosomes",
"description": "Quelles complications peuvent survenir avec des anomalies du Composant-7 ?\nLes anomalies peuvent-elles affecter la fertilité ?\nY a-t-il des risques de maladies associées ?\nLes complications sont-elles réversibles ?\nComment les complications sont-elles traitées ?",
"url": "https://questionsmedicales.fr/mesh/D064168?mesh_terms=High-Throughput+Screening+Assays#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Composant-7 du complexe de maintenance des minichromosomes",
"description": "Quels sont les facteurs de risque pour les anomalies du Composant-7 ?\nL'âge influence-t-il le risque d'anomalies ?\nLe mode de vie affecte-t-il le risque ?\nY a-t-il des antécédents familiaux à considérer ?\nLes infections pendant la grossesse sont-elles un facteur de risque ?",
"url": "https://questionsmedicales.fr/mesh/D064168?mesh_terms=High-Throughput+Screening+Assays#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une anomalie du Composant-7 ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques et des analyses de protéines peuvent identifier des anomalies."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer le Composant-7 ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests de Western blot et les analyses de PCR sont couramment utilisés."
}
},
{
"@type": "Question",
"name": "Y a-t-il des marqueurs spécifiques pour le Composant-7 ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des marqueurs protéiques spécifiques peuvent indiquer des dysfonctionnements."
}
},
{
"@type": "Question",
"name": "Le diagnostic nécessite-t-il une biopsie ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une biopsie peut être nécessaire pour des analyses plus approfondies."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent indiquer un problème avec le Composant-7 ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des anomalies dans la division cellulaire peuvent être des indicateurs."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une défaillance du Composant-7 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des troubles de la division cellulaire et des anomalies chromosomiques."
}
},
{
"@type": "Question",
"name": "Peut-on observer des symptômes cliniques ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes cliniques peuvent apparaître, mais ils sont souvent non spécifiques."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon les individus ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes peuvent varier en fonction de la gravité de l'anomalie."
}
},
{
"@type": "Question",
"name": "Y a-t-il des signes précoces d'anomalies ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes précoces peuvent inclure des retards de croissance cellulaire."
}
},
{
"@type": "Question",
"name": "Les symptômes sont-ils réversibles ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains symptômes peuvent être réversibles avec un traitement approprié."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les anomalies du Composant-7 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un mode de vie sain peut aider."
}
},
{
"@type": "Question",
"name": "Y a-t-il des facteurs environnementaux à éviter ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les toxines et les radiations peut réduire les risques d'anomalies."
}
},
{
"@type": "Question",
"name": "Des dépistages réguliers sont-ils recommandés ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dépistages réguliers peuvent aider à détecter des anomalies précocement."
}
},
{
"@type": "Question",
"name": "L'alimentation joue-t-elle un rôle dans la prévention ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut soutenir la santé cellulaire et réduire les risques."
}
},
{
"@type": "Question",
"name": "Les vaccinations peuvent-elles aider ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines vaccinations peuvent prévenir des infections qui affectent la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour les anomalies du Composant-7 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements peuvent inclure des thérapies géniques et des médicaments ciblés."
}
},
{
"@type": "Question",
"name": "La thérapie génique est-elle efficace ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique montre des résultats prometteurs dans certains cas."
}
},
{
"@type": "Question",
"name": "Des médicaments spécifiques sont-ils utilisés ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des inhibiteurs spécifiques peuvent être utilisés pour cibler les anomalies."
}
},
{
"@type": "Question",
"name": "Le traitement nécessite-t-il une surveillance régulière ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une surveillance régulière est essentielle pour évaluer l'efficacité."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires aux traitements ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des effets secondaires peuvent survenir, nécessitant une gestion attentive."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec des anomalies du Composant-7 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des cancers et des troubles génétiques."
}
},
{
"@type": "Question",
"name": "Les anomalies peuvent-elles affecter la fertilité ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines anomalies peuvent entraîner des problèmes de fertilité."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de maladies associées ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des risques accrus de maladies métaboliques peuvent être observés."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être gérées, mais pas toutes sont réversibles."
}
},
{
"@type": "Question",
"name": "Comment les complications sont-elles traitées ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement des complications dépend de leur nature et de leur gravité."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les anomalies du Composant-7 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des prédispositions génétiques et des expositions environnementales."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque d'anomalies ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'âge avancé peut augmenter le risque d'anomalies chromosomiques."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie malsain peut augmenter le risque d'anomalies génétiques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des antécédents familiaux à considérer ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux d'anomalies peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Les infections pendant la grossesse sont-elles un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections pendant la grossesse peuvent affecter le développement chromosomique."
}
}
]
}
]
}
Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China. zhjianw2@mail.sysu.edu.cn.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Medical Oncology of the Eastern Hospital, The First Affiliated Hospital of Sun Yat-sen University, Zhongshan Er Road, Guangzhou, 510080, China. drliheping@163.com.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China. fubinsh@mail.sysu.edu.cn.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Utilization of high-throughput biophysical screening techniques during early screening studies is warranted due to the limited amount of material and large number of samples. But the predictability of...
Bacterial two-component systems (TCSs), which typically consist of a sensor histidine kinase (HK) and a response regulator (RR), have been investigated as attractive antibacterial drug targets. Unfort...
Human sulfotransferase 1As (hSULT1As) play a crucial role in the metabolic clearance and detoxification of a diverse range of endogenous and exogenous substances, as well as in the bioactivation of so...
Organoids are three-dimensional structures that closely recapitulate tissue architecture and cellular composition, thereby holding great promise for organoid-based drug screening. Although growing in ...
In this study, the Z-stack imaging technique was used for the imaging of three-dimensional organoids to gather all the organoids' maximum cross sections in one imaging. The combination of live cell st...
We have established a novel quantitative high-throughput imaging assay that harnesses the scalability of organoid cultures. Using this assay, we can capture organoid growth over time, measure multiple...
In summary, combining the Z-stack imaging technique and fluorescent labeling methods, we established an assay for the imaging and analysis of three-dimensional organoids. Our data demonstrated the fea...
Fungal unspecific peroxygenases (UPOs) are arising as versatile biocatalysts for C-H oxyfunctionalization reactions. In recent years, several directed evolution studies have been conducted to design i...
Lymphocyte activation gene 3 (LAG-3) is a negative immune checkpoint and a key regulator of immune homeostasis with multiple biological activities related to T-cell functions. Fibrinogen-like protein ...
Environmental endocrine-disrupting chemicals (EDCs) interfere with the metabolism and actions of endogenous hormones. It has been well documented in numerous in vivo and in vitro studies that EDCs can...
Glycosaminoglycan synthases have immense potential in applications involving synthesis of oligosaccharides, using enzymatic approaches and construction of cell factories that produce polysaccharides a...
The drastically increasing consumption of petroleum-derived plastics hasserious environmental impacts and raises public concerns. Poly(ethylene terephthalate) (PET) is amongst the most extensively pro...
We present a microplate assay for the detection of HIV and SARS-CoV-2 which involves the preadsorption of carboxy-modified polystyrene microspheres to the microplate wells and their self-assembly lead...