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"name": "Diagnostic",
"headline": "Diagnostic sur Protéines intrinsèquement désordonnées",
"description": "Comment diagnostiquer une maladie liée aux IDP ?\nQuels tests sont utilisés pour les IDP ?\nLes IDP peuvent-elles être détectées par imagerie ?\nY a-t-il des biomarqueurs pour les IDP ?\nLes tests génétiques aident-ils pour les IDP ?",
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"description": "Comment traiter les maladies liées aux IDP ?\nY a-t-il des médicaments spécifiques pour les IDP ?\nLa thérapie génique aide-t-elle avec les IDP ?\nLes traitements naturels sont-ils efficaces pour les IDP ?\nLa physiothérapie aide-t-elle avec les IDP ?",
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"description": "Quelles complications peuvent survenir avec les IDP ?\nLes IDP peuvent-elles entraîner des maladies chroniques ?\nY a-t-il des risques de récidive avec les IDP ?\nLes IDP peuvent-elles affecter la qualité de vie ?\nLes IDP sont-elles liées à des troubles mentaux ?",
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"description": "Quels sont les facteurs de risque pour les IDP ?\nL'hérédité joue-t-elle un rôle dans les IDP ?\nL'exposition à des toxines influence-t-elle les IDP ?\nLe mode de vie affecte-t-il le risque d'IDP ?\nLes infections peuvent-elles être un facteur de risque ?",
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"@type": "Question",
"name": "Comment diagnostiquer une maladie liée aux IDP ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic repose sur des tests biochimiques et des analyses protéomiques."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour les IDP ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques comme la spectroscopie RMN et la chromatographie sont courantes."
}
},
{
"@type": "Question",
"name": "Les IDP peuvent-elles être détectées par imagerie ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, l'imagerie ne détecte pas directement les IDP, mais peut montrer des effets cellulaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des biomarqueurs pour les IDP ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines IDP peuvent servir de biomarqueurs, mais cela reste en recherche."
}
},
{
"@type": "Question",
"name": "Les tests génétiques aident-ils pour les IDP ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests génétiques peuvent identifier des mutations, mais pas spécifiquement les IDP."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont associés aux IDP ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes varient selon la maladie, incluant fatigue, douleurs et troubles neurologiques."
}
},
{
"@type": "Question",
"name": "Les IDP causent-elles des troubles neurologiques ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines IDP sont liées à des maladies neurodégénératives comme Alzheimer."
}
},
{
"@type": "Question",
"name": "Les IDP sont-elles liées à des cancers ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines IDP sont impliquées dans la régulation tumorale et peuvent favoriser le cancer."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des symptômes sans IDP ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, de nombreux symptômes peuvent être causés par d'autres facteurs non liés aux IDP."
}
},
{
"@type": "Question",
"name": "Les IDP provoquent-elles des douleurs articulaires ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies associées aux IDP peuvent entraîner des douleurs articulaires."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les maladies liées aux IDP ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un mode de vie sain peut réduire les risques."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle les IDP ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut soutenir la santé cellulaire, mais ne prévient pas directement les IDP."
}
},
{
"@type": "Question",
"name": "Le stress affecte-t-il les IDP ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress peut exacerber les symptômes, mais ne cause pas directement les IDP."
}
},
{
"@type": "Question",
"name": "L'exercice physique aide-t-il avec les IDP ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut améliorer la santé générale et réduire certains symptômes."
}
},
{
"@type": "Question",
"name": "Les contrôles médicaux réguliers sont-ils importants ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des contrôles réguliers peuvent aider à détecter précocement des problèmes liés aux IDP."
}
},
{
"@type": "Question",
"name": "Comment traiter les maladies liées aux IDP ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement dépend de la maladie spécifique et peut inclure médicaments et thérapies."
}
},
{
"@type": "Question",
"name": "Y a-t-il des médicaments spécifiques pour les IDP ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de médicaments spécifiques, mais des traitements ciblent les symptômes."
}
},
{
"@type": "Question",
"name": "La thérapie génique aide-t-elle avec les IDP ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est en recherche pour certaines maladies liées aux IDP."
}
},
{
"@type": "Question",
"name": "Les traitements naturels sont-ils efficaces pour les IDP ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains traitements naturels peuvent soulager les symptômes, mais manquent de preuves solides."
}
},
{
"@type": "Question",
"name": "La physiothérapie aide-t-elle avec les IDP ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la physiothérapie peut aider à gérer les symptômes et améliorer la qualité de vie."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec les IDP ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles neurologiques, des cancers et des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les IDP peuvent-elles entraîner des maladies chroniques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines IDP sont associées à des maladies chroniques comme la fibromyalgie."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de récidive avec les IDP ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies liées aux IDP peuvent avoir des risques de récidive, selon le cas."
}
},
{
"@type": "Question",
"name": "Les IDP peuvent-elles affecter la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les IDP peuvent gravement affecter la qualité de vie en raison des symptômes chroniques."
}
},
{
"@type": "Question",
"name": "Les IDP sont-elles liées à des troubles mentaux ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent un lien entre IDP et troubles mentaux, mais les recherches continuent."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les IDP ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des prédispositions génétiques, l'âge et des facteurs environnementaux."
}
},
{
"@type": "Question",
"name": "L'hérédité joue-t-elle un rôle dans les IDP ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines IDP ont une composante héréditaire, augmentant le risque de maladies."
}
},
{
"@type": "Question",
"name": "L'exposition à des toxines influence-t-elle les IDP ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certaines toxines peut augmenter le risque de maladies liées aux IDP."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque d'IDP ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie malsain, comme le tabagisme, peut augmenter le risque de maladies liées aux IDP."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles être un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales sont associées à un risque accru de maladies liées aux IDP."
}
}
]
}
]
}
Unicompartmental knee arthroplasty (UKA) has generally shown higher revision rates than TKA, and this is particularly true for the femoral component. A twin-peg femoral component (Oxford Partial) has ...
Using data from the Norwegian Arthroplasty Register, we asked: (1) Has the 5-year implant survival (free from revision for any cause) improved with the medial Oxford unicompartmental knee after the in...
We performed a registry-based observational study using data from the Norwegian Arthroplasty Register, a nationwide, mandatory and governmental registry with a high reporting rate. Between 2012 and 20...
The 5-year Kaplan-Meier overall implant survival (free from revision for any cause) for the medial Oxford Partial unicompartmental knee did not improve over the study period. The 5-year Kaplan-Meier s...
Considering that we found no difference in overall risk of revision during the first 5 years but we found a higher risk of revision for infection, periprosthetic fracture, and higher per implant cost,...
Level III, therapeutic study....
Factors associated with upper limb prosthesis adoption are not well understood. In this study, we explored how prosthesis usability experience relates to the extent of prosthesis adoption through the ...
A transfemoral bone-anchored prosthesis (BAP) is an alternative for the conventional socket-suspended prosthesis (SSP) in persons suffering from socket-related problems. In these persons, it has been ...
Do oxygen consumption, CoM and trunk dynamics during walking differ between satisfied transfemoral SSP- and BAP-users and able-bodied individuals (AB); and are CoM and trunk dynamics and pistoning pot...
Oxygen consumption was measured while participants walked on a treadmill at preferred speed, 30 % slower, and 30 % faster. At preferred speed, we also evaluated CoM deviation, root-mean-square values ...
We included BAP-users (n = 10), SSP-users (n = 10), and AB (n = 10). SSP-users demonstrated higher oxygen consumption, CoM and trunk RMS ML in comparison to AB during walking. BAP-users showed interme...
Our results indicate that satisfied SSP-users have increased oxygen consumption compared to AB subjects and use compensatory movements during walking. An assessment of CoM and trunk dynamics, and pist...
To allow an amputee resume healthy walking, a well-designed lower limb prosthesis is required. However, in many developing countries, the cost of high-tech and often imported prosthesis is out of the ...
Management of partial hand amputations is a notable clinical challenge. Historically, myoelectric prostheses have not allowed for independent digital control, resulting in unsatisfactory function and ...
Extensive proximal humeral bone loss in the setting of shoulder arthroplasty represents a difficult challenge for the treating surgeon. Achieving adequate fixation with standard humeral prostheses can...
We retrospectively reviewed all patients with minimum 2-year follow-up who underwent implantation of an RHRP for either (1) failed shoulder arthroplasty or (2) proximal humerus fracture with severe bo...
Of the 44 RHRPs evaluated, 93% (n = 39) had undergone prior surgery and 70% (n = 30) were performed for failed arthroplasty. ROM improved significantly in abduction by 22° (P = .006) and forward eleva...
These data demonstrate that the RHRP resulted in significant improvements in ROM, pain, and patient-reported outcome measures, without the risk of early humeral component loosening. RHRP represents an...
Measurement of prosthesis structural load, as an important way to quantify the interaction of the amputee user with the environment, may serve important purposes in the control of smart lower-limb pro...
We aimed to compare the postoperative clinical efficacy and safety of medial pivot (MP) prosthesis and posterior-stabilized (PS) prosthesis in the treatment of knee osteoarthritis (KOA)....
All studies involving MP and PS prosthesis in PubMed, EMBASE, Cochrane Library, and Web of Science were searched since the establishment of the database. The included outcomes were knee range of motio...
A total of 19 studies, consisting of 3592 patients and 3783 knees (MP: 1811 knees, PS: 1972 knees), were included in the meta-analysis. The WOMAC (MD = - 1.11, 95% CI - 1.98 to - 0.23; P = 0.01) and H...
The existing literature provided evidence to support better clinical effect and lower complication rate of MP prosthesis compared to PS prosthesis. These results provide a reference for clinicians whe...
Good to very good clinical results can be achieved in older patients with the implantation of a total elbow prosthesis in cases of distal humeral fractures by taking the morphological features of the ...
Hip-preserved reconstruction for patients with ultrashort proximal femur segments following extensive femoral diaphyseal tumor resection is a formidable undertaking. A customized intercalary prosthesi...
This study was designed to analyze and compare the differences in the biomechanical behavior between the normal femur and the femur with diaphyseal defects reconstructed by an intercalary prosthesis w...
The biomechanical results showed that normal-like stress and displacement distribution patterns were observed in the remaining proximal femur segments after reconstructions with the rhino horn-designe...
The rhino horn-designed uncemented stem is outstanding in precise shape matching and osseointegration. This novel prosthesis design may be beneficial in decreasing the risk of mechanical failure and a...