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"name": "Diagnostic",
"headline": "Diagnostic sur Protéines intrinsèquement désordonnées",
"description": "Comment diagnostiquer une maladie liée aux IDP ?\nQuels tests sont utilisés pour les IDP ?\nLes IDP peuvent-elles être détectées par imagerie ?\nY a-t-il des biomarqueurs pour les IDP ?\nLes tests génétiques aident-ils pour les IDP ?",
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"description": "Quels symptômes sont associés aux IDP ?\nLes IDP causent-elles des troubles neurologiques ?\nLes IDP sont-elles liées à des cancers ?\nPeut-on avoir des symptômes sans IDP ?\nLes IDP provoquent-elles des douleurs articulaires ?",
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"description": "Peut-on prévenir les maladies liées aux IDP ?\nL'alimentation influence-t-elle les IDP ?\nLe stress affecte-t-il les IDP ?\nL'exercice physique aide-t-il avec les IDP ?\nLes contrôles médicaux réguliers sont-ils importants ?",
"url": "https://questionsmedicales.fr/mesh/D064267?mesh_terms=Prosthesis+Design&page=3#section-prévention"
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"headline": "Traitements sur Protéines intrinsèquement désordonnées",
"description": "Comment traiter les maladies liées aux IDP ?\nY a-t-il des médicaments spécifiques pour les IDP ?\nLa thérapie génique aide-t-elle avec les IDP ?\nLes traitements naturels sont-ils efficaces pour les IDP ?\nLa physiothérapie aide-t-elle avec les IDP ?",
"url": "https://questionsmedicales.fr/mesh/D064267?mesh_terms=Prosthesis+Design&page=3#section-traitements"
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"name": "Complications",
"headline": "Complications sur Protéines intrinsèquement désordonnées",
"description": "Quelles complications peuvent survenir avec les IDP ?\nLes IDP peuvent-elles entraîner des maladies chroniques ?\nY a-t-il des risques de récidive avec les IDP ?\nLes IDP peuvent-elles affecter la qualité de vie ?\nLes IDP sont-elles liées à des troubles mentaux ?",
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"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Protéines intrinsèquement désordonnées",
"description": "Quels sont les facteurs de risque pour les IDP ?\nL'hérédité joue-t-elle un rôle dans les IDP ?\nL'exposition à des toxines influence-t-elle les IDP ?\nLe mode de vie affecte-t-il le risque d'IDP ?\nLes infections peuvent-elles être un facteur de risque ?",
"url": "https://questionsmedicales.fr/mesh/D064267?mesh_terms=Prosthesis+Design&page=3#section-facteurs de risque"
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"@type": "Question",
"name": "Comment diagnostiquer une maladie liée aux IDP ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic repose sur des tests biochimiques et des analyses protéomiques."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour les IDP ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques comme la spectroscopie RMN et la chromatographie sont courantes."
}
},
{
"@type": "Question",
"name": "Les IDP peuvent-elles être détectées par imagerie ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, l'imagerie ne détecte pas directement les IDP, mais peut montrer des effets cellulaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des biomarqueurs pour les IDP ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines IDP peuvent servir de biomarqueurs, mais cela reste en recherche."
}
},
{
"@type": "Question",
"name": "Les tests génétiques aident-ils pour les IDP ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests génétiques peuvent identifier des mutations, mais pas spécifiquement les IDP."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont associés aux IDP ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes varient selon la maladie, incluant fatigue, douleurs et troubles neurologiques."
}
},
{
"@type": "Question",
"name": "Les IDP causent-elles des troubles neurologiques ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines IDP sont liées à des maladies neurodégénératives comme Alzheimer."
}
},
{
"@type": "Question",
"name": "Les IDP sont-elles liées à des cancers ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines IDP sont impliquées dans la régulation tumorale et peuvent favoriser le cancer."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des symptômes sans IDP ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, de nombreux symptômes peuvent être causés par d'autres facteurs non liés aux IDP."
}
},
{
"@type": "Question",
"name": "Les IDP provoquent-elles des douleurs articulaires ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies associées aux IDP peuvent entraîner des douleurs articulaires."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les maladies liées aux IDP ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un mode de vie sain peut réduire les risques."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle les IDP ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut soutenir la santé cellulaire, mais ne prévient pas directement les IDP."
}
},
{
"@type": "Question",
"name": "Le stress affecte-t-il les IDP ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress peut exacerber les symptômes, mais ne cause pas directement les IDP."
}
},
{
"@type": "Question",
"name": "L'exercice physique aide-t-il avec les IDP ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut améliorer la santé générale et réduire certains symptômes."
}
},
{
"@type": "Question",
"name": "Les contrôles médicaux réguliers sont-ils importants ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des contrôles réguliers peuvent aider à détecter précocement des problèmes liés aux IDP."
}
},
{
"@type": "Question",
"name": "Comment traiter les maladies liées aux IDP ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement dépend de la maladie spécifique et peut inclure médicaments et thérapies."
}
},
{
"@type": "Question",
"name": "Y a-t-il des médicaments spécifiques pour les IDP ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de médicaments spécifiques, mais des traitements ciblent les symptômes."
}
},
{
"@type": "Question",
"name": "La thérapie génique aide-t-elle avec les IDP ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est en recherche pour certaines maladies liées aux IDP."
}
},
{
"@type": "Question",
"name": "Les traitements naturels sont-ils efficaces pour les IDP ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains traitements naturels peuvent soulager les symptômes, mais manquent de preuves solides."
}
},
{
"@type": "Question",
"name": "La physiothérapie aide-t-elle avec les IDP ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la physiothérapie peut aider à gérer les symptômes et améliorer la qualité de vie."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec les IDP ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles neurologiques, des cancers et des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les IDP peuvent-elles entraîner des maladies chroniques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines IDP sont associées à des maladies chroniques comme la fibromyalgie."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de récidive avec les IDP ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies liées aux IDP peuvent avoir des risques de récidive, selon le cas."
}
},
{
"@type": "Question",
"name": "Les IDP peuvent-elles affecter la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les IDP peuvent gravement affecter la qualité de vie en raison des symptômes chroniques."
}
},
{
"@type": "Question",
"name": "Les IDP sont-elles liées à des troubles mentaux ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent un lien entre IDP et troubles mentaux, mais les recherches continuent."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les IDP ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des prédispositions génétiques, l'âge et des facteurs environnementaux."
}
},
{
"@type": "Question",
"name": "L'hérédité joue-t-elle un rôle dans les IDP ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines IDP ont une composante héréditaire, augmentant le risque de maladies."
}
},
{
"@type": "Question",
"name": "L'exposition à des toxines influence-t-elle les IDP ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certaines toxines peut augmenter le risque de maladies liées aux IDP."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque d'IDP ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie malsain, comme le tabagisme, peut augmenter le risque de maladies liées aux IDP."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles être un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales sont associées à un risque accru de maladies liées aux IDP."
}
}
]
}
]
}
To investigate the differences in postoperative patellofemoral pressures and patellar tracking during at least three years of follow-up in patients using three prostheses of different designs in total...
RADIOGRAPHIC INVESTIGATIONS: The study included 401 patients who had a total of 480 knee prostheses implanted without patellar resurfacing. The prostheses used were Genesis II (external rotation desig...
Constructing a finite element model of the knee joint of a normal volunteer after total knee arthroplasty using different prostheses for nonpatellar replacement. The three models' von Mises stress dis...
RADIOGRAPHIC INVESTIGATIONS: A total of 456 knees of 384 patients were investigated at a 3-year follow-up after TKA without patellar resurfacing. There were no significant differences in patellar trac...
The von Mises stress distribution heat map showed that during flexion, the patellofemoral stresses were mainly concentrated on the lateral side of the prosthesis side, and the contact site gradually s...
In TKA without patellar resurfacing, a prosthesis with a deeper trochlear groove, a slightly higher lateral femoral condyle, and a more anatomically designed knee that better matches the patellar morp...
Upper limb robotic (myoelectric) prostheses are technologically advanced, but challenging to use. In response, substantial research is being done to develop person-specific prosthesis controllers that...
Maxillofacial prosthesis is an effective treatment for patients with facial sequelae, but it remains challenging for professionals due to its high esthetic complexity. This study describes a clinical ...
Among commercially-available upper-limb prostheses, the two most often used solutions are simple hook-style grippers and poly-articulated hands, which present a higher number of articulations and show...
The SoftHand Pro (SHP) is an artificial hand platform that has 19 independent joints (degrees-of-freedom), but is controlled by a single input. The design of this prosthesis is inspired by the concept...
The great versatility of the SoftHand Pro (a reasearch protpotype) permitted its adaptation to the user requirements. This was experienced by the SoftHand Pro Team during the preparation for different...
We introduced our pilots, the implementation of the two control modalities, and describe the successful participation in all CYBATHLON events. This work proves the versatility of the system towards th...
Prosthesis-patient mismatch (PPM), first described in 1978, occurs when a prosthetic valve functions normally, but has an effective orifice area that is too small relative to the patient's body surfac...
A 78-year-old male was admitted to our institute with increasing shortness of breath and decreased exercise tolerance. His increasing symptoms were not relieved with medical management. He had a compl...
Intraoperative extraction of this prosthesis proved technically challenging and a valve in valve successfully was implanted as a salvage procedure....
The procedure was successful, and the patient made a full recovery....
Open valve in valve implantation, despite technical difficulties, may be utilized as a salvage procedure....
To explore cognitive load in people with transfemoral amputations fitted with socket or bone-anchored prostheses by describing activity in the left and right dorsolateral prefrontal cortices during si...
Cross-sectional pilot study....
8 socket prosthesis users and 8 bone-anchored prosthesis users. All were fitted with microprocessor-controlled prosthetic knees....
Participants answered self-report questionnaires and performed gait tests during 1 single-task walking condition and 2 dual-task walking conditions. While walking, activity in the dorsolateral prefron...
Self-report measures and basic gait variables did not show differences between the groups. No obvious between-group differences were observed in the relative concentration of oxygenated haemoglobin fo...
This pilot study did not identify substantial differences in cognitive load or lateralization between socket prosthesis users and bone-anchored prosthesis users....
Prosthesis choice during aortic valve replacement (AVR) weighs lifelong anticoagulation with mechanical valves (M-AVR) against structural valve degeneration in bioprosthetic valves (B-AVR)....
The Nationwide Readmissions Database was queried to identify patients who underwent isolated surgical AVR between January 1, 2016 and December 31, 2018, stratifying by prothesis type. Propensity score...
Patients (n = 109,744) who underwent AVR (90,574 B-AVR and 19,170 M-AVR) were included. B-AVR patients were older (median 68 versus 57 y; P < 0.001) and had more comorbidities (mean Elixhauser score: ...
B-AVR patients had similar early outcomes compared to M-AVR patients, but lower rates of readmission. Bleeding, coagulopathy, and effusions are drivers of excess readmissions in M-AVR patients. Readmi...
This work presents a structural computational simulation of a polymeric aortic valve prosthesis, made with a hyperelastic material (Styrene-Ethylene/Propylene-Styrene). The valve has a suture ring, th...
To analyse data from patient information forms (PIFs) submitted to the manufacturer of a new three-piece inflatable penile prosthesis (IPP), the Rigicon Infla10®, to summarize early outcomes....
A retrospective review of PIFs from 319 patients implanted with the IPP between 6 January 2019 and 31 December 2021 was performed to assess device durability and rates of reoperation for infection, me...
The mean ± sd (range) follow-up was 21.2 ± 11 (5-36) months and the mean ± sd patient age was 58.5 ± 8.7 years. Of the total, 4.4% of devices required removal or revision. Complications included mecha...
The vast majority of the early Rigicon Infla10 IPPs implanted prior to January 2022 were included in this retrospective analysis of volunteered PIFs. These early results demonstrate initial durability...