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{
"@type": "Question",
"name": "Comment identifier un inducteur du CYP2D6 ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'identification se fait par l'analyse des médicaments et leur effet sur le métabolisme."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer l'activité du CYP2D6 ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques et des dosages de médicaments peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent une induction du CYP2D6 ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une diminution de l'efficacité des médicaments métabolisés par CYP2D6 peut indiquer une induction."
}
},
{
"@type": "Question",
"name": "Peut-on mesurer l'activité du CYP2D6 ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'activité peut être mesurée par des tests de métabolisme de médicaments spécifiques."
}
},
{
"@type": "Question",
"name": "Quels médicaments sont des inducteurs connus ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme la rifampicine et la carbamazépine sont des inducteurs connus."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent résulter d'une induction du CYP2D6 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une induction peut entraîner une réduction de l'efficacité des médicaments, causant des symptômes de maladie."
}
},
{
"@type": "Question",
"name": "Comment l'induction affecte-t-elle les médicaments ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut réduire la concentration plasmatique des médicaments, diminuant leur effet thérapeutique."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets secondaires liés aux inducteurs ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des effets secondaires peuvent survenir si les médicaments perdent leur efficacité."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques peuvent alerter sur une induction ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes de non-réponse au traitement peuvent alerter sur une induction du CYP2D6."
}
},
{
"@type": "Question",
"name": "L'induction peut-elle causer des symptômes d'intoxication ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Indirectement, si des médicaments sont sous-dosés, cela peut entraîner des symptômes d'intoxication."
}
},
{
"@type": "Question",
"name": "Comment prévenir l'induction du CYP2D6 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les inducteurs connus et surveiller les interactions médicamenteuses."
}
},
{
"@type": "Question",
"name": "Les patients doivent-ils être informés des inducteurs ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'éducation des patients sur les inducteurs est cruciale pour éviter des complications."
}
},
{
"@type": "Question",
"name": "Quelles précautions prendre lors de la prescription ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Évaluer les antécédents médicamenteux et les interactions potentielles avant de prescrire."
}
},
{
"@type": "Question",
"name": "Les médecins doivent-ils surveiller les inducteurs ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une surveillance régulière des médicaments inducteurs est recommandée."
}
},
{
"@type": "Question",
"name": "Y a-t-il des recommandations pour les prescripteurs ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des lignes directrices existent pour éviter les interactions avec les inducteurs."
}
},
{
"@type": "Question",
"name": "Comment gérer l'induction du CYP2D6 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est essentiel d'ajuster les doses des médicaments affectés par l'induction."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser des inhibiteurs du CYP2D6 ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des inhibiteurs peuvent être utilisés pour contrer l'effet des inducteurs."
}
},
{
"@type": "Question",
"name": "Quels médicaments sont souvent ajustés ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antidépresseurs et les antipsychotiques sont souvent ajustés en cas d'induction."
}
},
{
"@type": "Question",
"name": "Y a-t-il des alternatives aux inducteurs ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des médicaments non inducteurs peuvent être prescrits pour éviter l'interaction."
}
},
{
"@type": "Question",
"name": "Comment surveiller l'efficacité du traitement ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des suivis réguliers et des dosages de médicaments sont nécessaires pour évaluer l'efficacité."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec l'induction ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent une inefficacité thérapeutique et des effets indésirables."
}
},
{
"@type": "Question",
"name": "L'induction peut-elle entraîner des hospitalisations ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des hospitalisations peuvent être nécessaires en cas de complications graves."
}
},
{
"@type": "Question",
"name": "Quels risques sont associés à l'induction ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les risques incluent des interactions médicamenteuses et des effets secondaires graves."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications liées à l'induction ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est crucial d'ajuster les traitements et de surveiller les patients de près."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications à long terme ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications à long terme peuvent inclure des effets résiduels sur le métabolisme."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque d'induction ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'utilisation de certains médicaments et des variations génétiques."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il l'induction du CYP2D6 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'âge peut affecter le métabolisme et la réponse aux inducteurs."
}
},
{
"@type": "Question",
"name": "Les habitudes de vie jouent-elles un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des habitudes comme l'alcool et le tabac peuvent influencer l'induction."
}
},
{
"@type": "Question",
"name": "Y a-t-il des prédispositions génétiques ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines variations génétiques peuvent augmenter le risque d'induction."
}
},
{
"@type": "Question",
"name": "Les interactions médicamenteuses sont-elles un facteur ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les interactions avec d'autres médicaments peuvent augmenter le risque d'induction."
}
}
]
}
]
}
Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Department of Pediatrics, Children's Mercy Kansas City, Kansas City, Missouri, USA.
School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.
Publications dans "Inducteurs du cytochrome P-450 CYP2D6" :
Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Department of Pediatrics, Children's Mercy Kansas City, Kansas City, Missouri, USA.
School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.
Publications dans "Inducteurs du cytochrome P-450 CYP2D6" :
School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.
Biostatistics & Epidemiology Core, Division of Health Services and Outcomes Research, Department of Pediatrics, Children's Mercy Kansas City, Kansas City, Missouri, USA.
Division of Developmental and Behavioral Sciences, Department of Pediatrics, Children's Mercy Kansas City, Kansas City, Missouri, USA.
Publications dans "Inducteurs du cytochrome P-450 CYP2D6" :
Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Department of Pediatrics, Children's Mercy Kansas City, Kansas City, Missouri, USA.
School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.
Publications dans "Inducteurs du cytochrome P-450 CYP2D6" :
Mental Health Neuroscience Research Department, Division of Psychiatry, University College London, London, UK. e.bramon@ucl.ac.uk.
Institute of Psychiatry, Psychology and Neuroscience, King's College London and South London and Maudsley NHS Foundation Trust, London, UK. e.bramon@ucl.ac.uk.
Institute of Cognitive Neuroscience, University College London, London, UK. e.bramon@ucl.ac.uk.
Publications dans "Inducteurs du cytochrome P-450 CYP2D6" :
Many dynamic structural models that include health as a state variable use categorical self-reported health status (SRHS) as their sole empirical measure of health. Commonly, transition probabilities ...
Pregnancy is associated with physiological changes such as increased body mass index, postural changes, hormonal imbalance and changes in foot morphology. Due to an increased uterus and body mass, the...
A quantitative approach, using a descriptive cross-sectional study design was utilized and a validated foot health status questionnaire was used. Data was analysed using a Statistical Package for Soci...
All pregnant women had a poor foot health status in the area of vigour, particularly in the third trimester. In the third trimester, women's physical activity was diminished and they appeared to have ...
As a woman progresses in her pregnancy, her foot health status declined in the areas of footwear, physical activity and vigour....
Working in the field of endoscopy is associated with physical and psychological challenges, but we lack data as to whether it influences the health status of endoscopy personnel. The aim of the presen...
In 2019, a standardized questionnaire of Hogrefe Publishers and a self-designed SurveyMonkey questionnaire were sent online to doctors (n=326) and nursing staff (n=234) working in the field of gastroi...
Compared to a standard population of identical age and gender distribution, endoscopy personnel in Austria have more health-related complaints. Compared to doctors, nursing staff experience greater ad...
The results of the survey showed that persons working in endoscopy have slightly greater health problems than the standard population. Nursing staff are affected more severely than doctors. These data...
We investigate the impact of the Great Recession in Italy on the incidence of chronic diseases using new individual longitudinal data from Electronic Health Records. We exploit the exogenous shock in ...
Spirituality is a health protection factor recognised in the scientific literature. However, few studies have evaluated its impact on French-speaking populations, in secularised societies and even few...
Due to an increasing aging population, China has experienced a rapid expansion in its internal older migrant population who face greater health risks and who have a relatively high demand for health e...
This study analyzed the impact of public health education on the health of the older migrant population in China....
Based on data obtained from the National Migrant Population Health and Family Planning Dynamic Monitor Survey (2018), logistic models and propensity score matching were used to analyze the impact of p...
The self-assessed health of China's older migrant population was good, and the acceptance rate of public health education was 40.81%. The public health status of the older migrant population receiving...
Public health education positively affected the health status of the older migrant population. The characteristics and preferences of the older migrant population involving different genders, regions,...
The sustained growth of older people and the epidemiological shift from communicable to chronic health problems have attracted increased attention to geriatric wellbeing, including oral health....
To evaluate the oral health of urban community-dwelling older people and identify their priority oral health needs....
We recruited 352 adults aged ≥ 65 years in 2015 from social organizations and primary healthcare centres in Beirut and its suburbs. Older people underwent dental examination including the decayed, mis...
Missing teeth contributed most to high DMFT score. Mean PI and root caries indices were high. Mean FU scores were low, but higher in women and in complete denture wearers. Lower numbers of remaining m...
We observed poor oral health, particularly missing teeth and low FUs, in older people, warranting interventions to integrate oral health within the scope of geriatric general health....
This study investigated differences in unhealthy lifestyle behaviors (ULBs) between workers and nonworkers and demonstrated the association of ULBs with occupational characteristics among workers. Thi...
Dental caries in permanent teeth is one of the most common health issues-despite being preventable in early stages-due to inadequate regulation of preventive dental services in many countries. This st...
This mixed-method study analysed data from 19 member countries of the Organisation for Economic Co-operation and Development (OECD). Oral health outcomes were measured using decayed missing and filled...
The most common preventive policy category is the availability of free dental services for children (78.95%), and the least common is policy mandating dental services for children (26.32%). The oral h...
A percentage increase in oral health expenditure is associated with a 4.42 reduction in DMFT. The existence of legal policy mandating dental care for children is associated with a 1.32 reduction in me...
Headache is an illness with high prevalence and adverse effects on quality of life. As oral or dental problems such as pain can trigger or aggravate it, we aimed to investigate and compare oral and de...
The present case-control study included 60 patients with chronic headaches (case) and 60 healthy individuals (control) in Rasht, Iran. The demographic characteristics and clinical examinations, includ...
The case group consisted of 25 men (41.7%) and 35 women (58.3%) with an average age of 32.55 ± 6.62 years, while the control group had 27 men (45%) and 33 women (55%) with an average age of 30.95 ± 6....
It seems that chronic headaches do not significantly affect the oral and dental health of the sufferers. Moreover, it appears that these patients are well aware of the role of oral and dental hygiene ...