Titre : Inducteurs du cytochrome P-450 CYP2D6

Inducteurs du cytochrome P-450 CYP2D6 : Questions médicales fréquentes

Termes MeSH sélectionnés :

Robotics
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"headline": "Symptômes sur Inducteurs du cytochrome P-450 CYP2D6", "description": "Quels symptômes peuvent résulter d'une induction du CYP2D6 ?\nComment l'induction affecte-t-elle les médicaments ?\nY a-t-il des effets secondaires liés aux inducteurs ?\nQuels signes cliniques peuvent alerter sur une induction ?\nL'induction peut-elle causer des symptômes d'intoxication ?", "url": "https://questionsmedicales.fr/mesh/D065699?mesh_terms=Robotics&page=998#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Inducteurs du cytochrome P-450 CYP2D6", "description": "Comment prévenir l'induction du CYP2D6 ?\nLes patients doivent-ils être informés des inducteurs ?\nQuelles précautions prendre lors de la prescription ?\nLes médecins doivent-ils surveiller les inducteurs ?\nY a-t-il des recommandations pour les prescripteurs ?", "url": "https://questionsmedicales.fr/mesh/D065699?mesh_terms=Robotics&page=998#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Inducteurs du cytochrome P-450 CYP2D6", "description": "Comment gérer l'induction du CYP2D6 ?\nPeut-on utiliser des inhibiteurs du CYP2D6 ?\nQuels médicaments sont souvent ajustés ?\nY a-t-il des alternatives aux inducteurs ?\nComment surveiller l'efficacité du traitement ?", "url": "https://questionsmedicales.fr/mesh/D065699?mesh_terms=Robotics&page=998#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Inducteurs du cytochrome P-450 CYP2D6", "description": "Quelles complications peuvent survenir avec l'induction ?\nL'induction peut-elle entraîner des hospitalisations ?\nQuels risques sont associés à l'induction ?\nComment gérer les complications liées à l'induction ?\nY a-t-il des complications à long terme ?", "url": "https://questionsmedicales.fr/mesh/D065699?mesh_terms=Robotics&page=998#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Inducteurs du cytochrome P-450 CYP2D6", "description": "Quels sont les facteurs de risque d'induction ?\nL'âge influence-t-il l'induction du CYP2D6 ?\nLes habitudes de vie jouent-elles un rôle ?\nY a-t-il des prédispositions génétiques ?\nLes interactions médicamenteuses sont-elles un facteur ?", "url": "https://questionsmedicales.fr/mesh/D065699?mesh_terms=Robotics&page=998#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment identifier un inducteur du CYP2D6 ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "L'identification se fait par l'analyse des médicaments et leur effet sur le métabolisme." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour évaluer l'activité du CYP2D6 ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests génétiques et des dosages de médicaments peuvent être utilisés." } }, { "@type": "Question", "name": "Quels signes indiquent une induction du CYP2D6 ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Une diminution de l'efficacité des médicaments métabolisés par CYP2D6 peut indiquer une induction." } }, { "@type": "Question", "name": "Peut-on mesurer l'activité du CYP2D6 ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'activité peut être mesurée par des tests de métabolisme de médicaments spécifiques." } }, { "@type": "Question", "name": "Quels médicaments sont des inducteurs connus ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Des médicaments comme la rifampicine et la carbamazépine sont des inducteurs connus." } }, { "@type": "Question", "name": "Quels symptômes peuvent résulter d'une induction du CYP2D6 ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Une induction peut entraîner une réduction de l'efficacité des médicaments, causant des symptômes de maladie." } }, { "@type": "Question", "name": "Comment l'induction affecte-t-elle les médicaments ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Elle peut réduire la concentration plasmatique des médicaments, diminuant leur effet thérapeutique." } }, { "@type": "Question", "name": "Y a-t-il des effets secondaires liés aux inducteurs ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des effets secondaires peuvent survenir si les médicaments perdent leur efficacité." } }, { "@type": "Question", "name": "Quels signes cliniques peuvent alerter sur une induction ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Des signes de non-réponse au traitement peuvent alerter sur une induction du CYP2D6." } }, { "@type": "Question", "name": "L'induction peut-elle causer des symptômes d'intoxication ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Indirectement, si des médicaments sont sous-dosés, cela peut entraîner des symptômes d'intoxication." } }, { "@type": "Question", "name": "Comment prévenir l'induction du CYP2D6 ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Éviter les inducteurs connus et surveiller les interactions médicamenteuses." } }, { "@type": "Question", "name": "Les patients doivent-ils être informés des inducteurs ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'éducation des patients sur les inducteurs est cruciale pour éviter des complications." } }, { "@type": "Question", "name": "Quelles précautions prendre lors de la prescription ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Évaluer les antécédents médicamenteux et les interactions potentielles avant de prescrire." } }, { "@type": "Question", "name": "Les médecins doivent-ils surveiller les inducteurs ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une surveillance régulière des médicaments inducteurs est recommandée." } }, { "@type": "Question", "name": "Y a-t-il des recommandations pour les prescripteurs ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des lignes directrices existent pour éviter les interactions avec les inducteurs." } }, { "@type": "Question", "name": "Comment gérer l'induction du CYP2D6 ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Il est essentiel d'ajuster les doses des médicaments affectés par l'induction." } }, { "@type": "Question", "name": "Peut-on utiliser des inhibiteurs du CYP2D6 ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des inhibiteurs peuvent être utilisés pour contrer l'effet des inducteurs." } }, { "@type": "Question", "name": "Quels médicaments sont souvent ajustés ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Les antidépresseurs et les antipsychotiques sont souvent ajustés en cas d'induction." } }, { "@type": "Question", "name": "Y a-t-il des alternatives aux inducteurs ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des médicaments non inducteurs peuvent être prescrits pour éviter l'interaction." } }, { "@type": "Question", "name": "Comment surveiller l'efficacité du traitement ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Des suivis réguliers et des dosages de médicaments sont nécessaires pour évaluer l'efficacité." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec l'induction ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications incluent une inefficacité thérapeutique et des effets indésirables." } }, { "@type": "Question", "name": "L'induction peut-elle entraîner des hospitalisations ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des hospitalisations peuvent être nécessaires en cas de complications graves." } }, { "@type": "Question", "name": "Quels risques sont associés à l'induction ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Les risques incluent des interactions médicamenteuses et des effets secondaires graves." } }, { "@type": "Question", "name": "Comment gérer les complications liées à l'induction ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Il est crucial d'ajuster les traitements et de surveiller les patients de près." } }, { "@type": "Question", "name": "Y a-t-il des complications à long terme ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Des complications à long terme peuvent inclure des effets résiduels sur le métabolisme." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque d'induction ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent l'utilisation de certains médicaments et des variations génétiques." } }, { "@type": "Question", "name": "L'âge influence-t-il l'induction du CYP2D6 ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'âge peut affecter le métabolisme et la réponse aux inducteurs." } }, { "@type": "Question", "name": "Les habitudes de vie jouent-elles un rôle ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des habitudes comme l'alcool et le tabac peuvent influencer l'induction." } }, { "@type": "Question", "name": "Y a-t-il des prédispositions génétiques ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines variations génétiques peuvent augmenter le risque d'induction." } }, { "@type": "Question", "name": "Les interactions médicamenteuses sont-elles un facteur ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les interactions avec d'autres médicaments peuvent augmenter le risque d'induction." } } ] } ] }

Sources (10000 au total)

Robotic approach for retromuscular ventral hernia repair may be associated with improved wound morbidity in high-risk patients: a propensity score analysis.

Retromuscular sublay (RMS) technique for repair of ventral hernias has gained popularity due to lower risk of recurrence and wound complications. Robotic approaches to RMS have been shown to decrease ... A retrospective review of elective robotic and open RMS repairs in the ACHQC database was performed. Patients deemed to be high-risk for wound complications were included: adult patients with BMI grea... A total of 917 patients met inclusion criteria. After propensity score matching, 211 patients matched for each approach. There was no difference in overall SSO (18% for Open vs 23% for Robotic, p = 0.... In this analysis, a robotic approach was associated with decreased rates of SSI and SSOPI in obese patients who were either current smokers or diabetics. In effort to reduce wound morbidity and the as...

Chronic kidney disease and Charlson comorbidity index predict complications after robot-assisted radical cystectomy: A single-center study in Japan.

To investigate preoperative patient factors that may predict the occurrence of perioperative complications following robot-assisted radical cystectomy at a single center in Japan.... From 2013 to 2022, 103 patients underwent RARC at our institution. Complications within 90 days after surgery were assessed using the Clavien-Dindo classification. Preoperative characteristics and sur... Overall, 27% of patients (27/103) experienced grade 3 or higher complications. The cohort that developed complications ≥grade 3 exhibited significantly higher Charlson comorbidity index (p = 0.046) an... Our results suggest that the Charlson comorbidity index and preoperative estimated glomerular filtration rate may be predictors of perioperative complications. It is important to evaluate the patient'...

Impact of Liver Cirrhosis, Severity of Cirrhosis, and Portal Hypertension on the Difficulty and Outcomes of Laparoscopic and Robotic Major Liver Resections for Primary Liver Malignancies.

Minimally invasive liver resections (MILR) offer potential benefits such as reduced blood loss and morbidity compared with open liver resections. Several studies have suggested that the impact of cirr... A total of 2534 patients undergoing minimally invasive major hepatectomies (MIMH) for primary malignancies across 58 centers worldwide were retrospectively reviewed. Propensity score (PSM) and coarsen... A total of 1353 patients (53%) had no cirrhosis, 1065 (42%) had Child-Pugh A and 116 (4%) had Child-Pugh B cirrhosis. Matched comparison between non-cirrhotics vs Child-Pugh A cirrhosis demonstrated c... The presence and severity of cirrhosis affected the difficulty and impacted the outcomes of MIMH, resulting in higher blood transfusion rates, increased postoperative morbidity, and longer hospitaliza...

Permanent stoma rate and long-term stoma complications in laparoscopic, robot-assisted, and transanal total mesorectal excisions: a retrospective cohort study.

The surgical resection of rectal carcinoma is associated with a high risk of permanent stoma rate. Primary anastomosis rate is suggested to be higher in robot-assisted and transanal total mesorectal e... Patients undergoing total mesorectal excision for MRI-defined rectal cancer between 2015 and 2017 in 11 centers highly experienced in laparoscopic, robot-assisted or transanal total mesorectal excisio... In total, 1198 patients were included. Permanent stoma rate after low anterior resection (with anastomosis or with an end colostomy) was 40.1% in patients undergoing laparoscopic surgery, 21.3% in pat... The robot-assisted and transanal techniques are associated with a lower permanent stoma rate in patients who underwent a low anterior resection....

Study protocol for a randomised controlled trial to determine the efficacy of an intensive seated postural intervention delivered with robotic and rigid trunk support systems.

Children with cerebral palsy (CP) classified as gross motor function classification system (GMFCS) levels III-IV demonstrate impaired sitting and reaching control abilities that hamper their overall f... We will recruit 82 participants with CP, GMFCS III-IV, and aged 6-17 years. Randomisation using concealed allocation to either the TruST-support or static trunk-support intervention will be conducted ... The study was approved by the Columbia University Institutional Review Board (AAAS7804). This study is funded by the National Institutes of Health (1R01HD101903-01) and is registered at clinicaltrials... NCT04897347; clinicaltrials.gov....

Analysis of training pathway to reach expert performance levels based on proficiency-based progression in robotic-assisted minimally invasive esophagectomy (RAMIE).

Robotic-assisted minimally invasive esophagectomy (RAMIE) was first introduced in 2003 and has since then shown to significantly improve the postoperative course. Previous studies have shown that a st... All patients undergoing RAMIE performed by two experienced surgeons for esophageal cancer since the introduction of the robotic technique in 2017 was included in this analysis. Intraoperative outcomes... From 06/2017 to 03/2022, a total of 154 patients underwent RAMIE at our facility and were included in the analysis. An advancement in performance level was observed for total operating time after 70 c... Our data and analysis showed the progression from proficient to expert performance levels during the implementation of RAMIE at a European high-volume center. Further analysis of surgeons, especially ...

Impact of minimally invasive surgery on surgical outcomes for obese women with endometrial cancer following robotic surgery introduction; a single centre study.

The aim was to assess the surgical outcomes in obese women with endometrial cancer following robotic surgery introduction in a London tertiary gynaecological cancer unit.... Data was prospectively collected for 281 women undergoing endometrial cancer surgery in 2016, 2018 and 2019 (robotic surgery was introduced in November 2017).... The proportion of obese and morbidly obese patients undergoing minimally invasive surgery (MIS) significantly increased following robotic surgery introduction from 43.8% to 69.6% (p < 0.001). Overall ... Robotic surgery led to a significant rise in MIS and improved surgical outcomes for obese and morbidly obese women with endometrial cancer within 12 months of its introduction....