Effect of pistachio on brachial artery diameter and flow-mediated dilatation: A systematic review and meta-analysis of randomized, controlled-feeding clinical studies.
Pistachio
brachial artery diameter
endothelial reactivity
flow mediated dilatation
meta-analysis
Journal
Critical reviews in food science and nutrition
ISSN: 1549-7852
Titre abrégé: Crit Rev Food Sci Nutr
Pays: United States
ID NLM: 8914818
Informations de publication
Date de publication:
2019
2019
Historique:
pubmed:
31
8
2017
medline:
18
7
2019
entrez:
31
8
2017
Statut:
ppublish
Résumé
Results of previous clinical trials evaluating the effect of pistachio supplementation on endothelial reactivity (ER) are controversial. We aimed to assess the impact of pistachio on ER through systematic review of literature and meta-analysis of available randomized, controlled-feeding clinical studies (RCTs). The literature search included SCOPUS, PubMed-Medline, ISI Web of Science and Google Scholar databases up to 1st August 2017 to identify RCTs investigating the impact of pistachio on ER. Two independent reviewers extracted data on study characteristics, methods and outcomes. Overall, the impact of pistachio on ER was reported in 4 trials. The meta-analysis did not suggest a significant change in brachial artery flow-mediated dilatation (FMD) (WMD: +0.28%; 95%CI: -0.58, 1.13; p = 0.525) while brachial artery diameter (BAD) improved (WMD: +0.04%; 95%CI: 0.03, 0.06; p<0.001) following pistachios consumption. The present meta-analysis suggests a significant effect of pistachios on ER, affecting BAD but not FMD.
Sections du résumé
BACKGROUND
BACKGROUND
Results of previous clinical trials evaluating the effect of pistachio supplementation on endothelial reactivity (ER) are controversial.
AIMS
OBJECTIVE
We aimed to assess the impact of pistachio on ER through systematic review of literature and meta-analysis of available randomized, controlled-feeding clinical studies (RCTs).
METHODS
METHODS
The literature search included SCOPUS, PubMed-Medline, ISI Web of Science and Google Scholar databases up to 1st August 2017 to identify RCTs investigating the impact of pistachio on ER. Two independent reviewers extracted data on study characteristics, methods and outcomes. Overall, the impact of pistachio on ER was reported in 4 trials.
RESULTS
RESULTS
The meta-analysis did not suggest a significant change in brachial artery flow-mediated dilatation (FMD) (WMD: +0.28%; 95%CI: -0.58, 1.13; p = 0.525) while brachial artery diameter (BAD) improved (WMD: +0.04%; 95%CI: 0.03, 0.06; p<0.001) following pistachios consumption.
CONCLUSION
CONCLUSIONS
The present meta-analysis suggests a significant effect of pistachios on ER, affecting BAD but not FMD.
Identifiants
pubmed: 28853908
doi: 10.1080/10408398.2017.1368007
doi:
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM