Evaluation of left ventricular mass on cadmium-zinc-telluride imaging: Validation against cardiac magnetic resonance.


Journal

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
ISSN: 1532-6551
Titre abrégé: J Nucl Cardiol
Pays: United States
ID NLM: 9423534

Informations de publication

Date de publication:
06 2019
Historique:
received: 24 08 2017
accepted: 26 09 2017
pubmed: 19 10 2017
medline: 22 8 2020
entrez: 19 10 2017
Statut: ppublish

Résumé

Single-photon emission computed tomography has shown relevant limitations in the quantification of left ventricular (LV) mass. We sought to compare the estimates of LV mass on Cadmium-Zinc-Telluride (CZT) myocardial perfusion imaging (MPI) as compared to cardiac magnetic resonance (CMR). Twenty-five patients underwent MPI on a CZT camera and CMR on a 1.5 T scanner within 12 ± 3 weeks. LV mass was quantified on CZT images using two softwares: 4D-MSPECT (4DM) and Emory Cardiac Toolbox (ECTb). LV mass by CMR was quantified using MASS software (Medis, Leiden, The Netherlands). LV mass values obtained with 4DM and ECTb were highly reproducible [intraclass correlation coefficients .98 (95% CI .97-.99), and .98 (95% CI 0.97-.99), respectively]. The mean LVM mass values were 151 ± 44 g on CMR, 151 ± 43 g with 4DM (P = NS vs CMR), and 157 ± 42 g with ECTb (P < .001 vs CMR; P = .007 vs 4DM) CZT images. There was an excellent correlation between LV mass values between CMR and both 4DM (R The evaluation of LV mass is feasible on CZT images, showing excellent agreement with CMR.

Sections du résumé

BACKGROUND
Single-photon emission computed tomography has shown relevant limitations in the quantification of left ventricular (LV) mass. We sought to compare the estimates of LV mass on Cadmium-Zinc-Telluride (CZT) myocardial perfusion imaging (MPI) as compared to cardiac magnetic resonance (CMR).
METHODS AND RESULTS
Twenty-five patients underwent MPI on a CZT camera and CMR on a 1.5 T scanner within 12 ± 3 weeks. LV mass was quantified on CZT images using two softwares: 4D-MSPECT (4DM) and Emory Cardiac Toolbox (ECTb). LV mass by CMR was quantified using MASS software (Medis, Leiden, The Netherlands). LV mass values obtained with 4DM and ECTb were highly reproducible [intraclass correlation coefficients .98 (95% CI .97-.99), and .98 (95% CI 0.97-.99), respectively]. The mean LVM mass values were 151 ± 44 g on CMR, 151 ± 43 g with 4DM (P = NS vs CMR), and 157 ± 42 g with ECTb (P < .001 vs CMR; P = .007 vs 4DM) CZT images. There was an excellent correlation between LV mass values between CMR and both 4DM (R
CONCLUSIONS
The evaluation of LV mass is feasible on CZT images, showing excellent agreement with CMR.

Identifiants

pubmed: 29043554
doi: 10.1007/s12350-017-1086-6
pii: 10.1007/s12350-017-1086-6
doi:

Substances chimiques

CdZnTe 0
Cadmium 00BH33GNGH
Zinc J41CSQ7QDS
Tellurium NQA0O090ZJ

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

899-905

Commentaires et corrections

Type : CommentIn

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Auteurs

Alessia Gimelli (A)

Fondazione Toscana/CNR G. Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy.

Riccardo Liga (R)

Dipartimento di Patologia Chirurgica, Molecolare e dell'Area Critica, Università di Pisa, Pisa, Italy. riccardo.liga@gmail.com.

Serena Magro (S)

Fondazione Toscana/CNR G. Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy.
Department of Cardiology, University of Palermo, Palermo, Italy.

Salvatore Novo (S)

Department of Cardiology, University of Palermo, Palermo, Italy.

Roberto Pedrinelli (R)

Dipartimento di Patologia Chirurgica, Molecolare e dell'Area Critica, Università di Pisa, Pisa, Italy.

Anna Sonia Petronio (AS)

Dipartimento di Patologia Chirurgica, Molecolare e dell'Area Critica, Università di Pisa, Pisa, Italy.

Paolo Marzullo (P)

Fondazione Toscana/CNR G. Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy.
Institute of Clinical Physiology, CNR, Pisa, Italy.

Alessia Pepe (A)

Fondazione Toscana/CNR G. Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy.

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Classifications MeSH