Blood pressure reduction in hypertensive acute ischemic stroke patients does not affect cerebral blood flow.
Aged
Antihypertensive Agents
/ therapeutic use
Blood Pressure
/ drug effects
Brain Ischemia
/ complications
Cerebrovascular Circulation
/ drug effects
Female
Humans
Hypertension
/ complications
Labetalol
/ therapeutic use
Male
Middle Aged
Nitroglycerin
/ therapeutic use
Stroke
/ complications
Vasodilator Agents
/ therapeutic use
Blood pressure
acute ischemic stroke
cerebral blood flow
labetalol
nitroglycerin
Journal
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
ISSN: 1559-7016
Titre abrégé: J Cereb Blood Flow Metab
Pays: United States
ID NLM: 8112566
Informations de publication
Date de publication:
09 2019
09 2019
Historique:
pubmed:
9
5
2018
medline:
27
5
2020
entrez:
9
5
2018
Statut:
ppublish
Résumé
The effect of blood pressure (BP) reduction on cerebral blood flow (CBF) in acute ischemic stroke is unknown. We measured regional CBF with perfusion-weighted MRI before and after BP treatment in a three-armed non-randomized prospective controlled trial. Treatment arm assignment was based on acute mean arterial pressure (MAP). Patients with (MAP) >120 mmHg (
Identifiants
pubmed: 29737226
doi: 10.1177/0271678X18774708
pmc: PMC6727146
doi:
Substances chimiques
Antihypertensive Agents
0
Vasodilator Agents
0
Nitroglycerin
G59M7S0WS3
Labetalol
R5H8897N95
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1878-1887Subventions
Organisme : CIHR
ID : G11816079
Pays : Canada
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