Relationship of spirometric, body plethysmographic, and diffusing capacity parameters to emphysema scores derived from CT scans.
COPD
CT scan
body plethysmography
emphysema
lung function
Journal
Chronic respiratory disease
ISSN: 1479-9731
Titre abrégé: Chron Respir Dis
Pays: England
ID NLM: 101197408
Informations de publication
Date de publication:
Historique:
pubmed:
11
5
2018
medline:
9
6
2020
entrez:
11
5
2018
Statut:
ppublish
Résumé
Phenotyping of chronic obstructive pulmonary disease (COPD) with computed tomography (CT) is used to distinguish between emphysema- and airway-dominated type. The phenotype is reflected in correlations with lung function measures. Among these, the relative value of body plethysmography has not been quantified. We addressed this question using CT scans retrospectively collected from clinical routine in a large COPD cohort. Three hundred and thirty five patients with baseline data of the German COPD cohort COPD and Systemic Consequences-Comorbidities Network were included. CT scans were primarily evaluated using a qualitative binary emphysema score. The binary score was positive for emphysema in 52.5% of patients, and there were significant differences between the positive/negative groups regarding forced expiratory volume in 1 second (FEV
Identifiants
pubmed: 29742906
doi: 10.1177/1479972318775423
pmc: PMC6302978
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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