Impact of additional tricuspid valve annuloplasty in TOF patients undergoing pulmonary valve replacement.


Journal

The Journal of cardiovascular surgery
ISSN: 1827-191X
Titre abrégé: J Cardiovasc Surg (Torino)
Pays: Italy
ID NLM: 0066127

Informations de publication

Date de publication:
Apr 2019
Historique:
pubmed: 23 5 2018
medline: 15 3 2019
entrez: 23 5 2018
Statut: ppublish

Résumé

Many patients with tetralogy of Fallot (TOF) who underwent surgical correction of their congenital cardiac malformation during infancy develop right ventricular dysfunction and exercise intolerance in the long term. The right ventricle (RV) dilates due to the development of severe pulmonary regurgitation (and secondary tricuspid insufficiency). To reduce RV dilation and improve exercise tolerance pulmonary valve replacement (PVR) is the common therapeutic strategy. Whether concomitant tricuspid valve repair (TVR) is beneficial in these pure volume-overload conditions is still unknown. Twenty-eight adults who received surgical PVR were included in the study and perioperative data including operative records, postoperative course and echocardiography before and after surgery was analyzed retrospectively. Mean age of the patients was 41.1±13.5 years and PVR with Carpentier Edwards Perimount bioprostheses was performed 32.0±9.5 years after initial cardiac surgery. Preoperative echocardiography revealed moderate RV dilation in 60.7% of the patients and severe pulmonary valve regurgitation in 82.3%. Ten patients underwent additional TVR. Indication was purely based on annular dilation (>40 mm), independent from the degree of tricuspid insufficiency. Periprocedural data of both groups did not differ significantly. However, ICU stay was significantly increased in patients who underwent additional TVR (P=0.0420) and these patients developed more complications (P=0.0407) while postoperative echography showed the same recovery of the RV function and diameters, independent of concomitant TVR. In grown-ups with congenital heart disease surgical PVR with or without TVR is a safe procedure with good short-term outcomes. As the RV remodels after volume reduction, indication for concomitant TVR should be restrictive.

Sections du résumé

BACKGROUND BACKGROUND
Many patients with tetralogy of Fallot (TOF) who underwent surgical correction of their congenital cardiac malformation during infancy develop right ventricular dysfunction and exercise intolerance in the long term. The right ventricle (RV) dilates due to the development of severe pulmonary regurgitation (and secondary tricuspid insufficiency). To reduce RV dilation and improve exercise tolerance pulmonary valve replacement (PVR) is the common therapeutic strategy. Whether concomitant tricuspid valve repair (TVR) is beneficial in these pure volume-overload conditions is still unknown.
METHODS METHODS
Twenty-eight adults who received surgical PVR were included in the study and perioperative data including operative records, postoperative course and echocardiography before and after surgery was analyzed retrospectively.
RESULTS RESULTS
Mean age of the patients was 41.1±13.5 years and PVR with Carpentier Edwards Perimount bioprostheses was performed 32.0±9.5 years after initial cardiac surgery. Preoperative echocardiography revealed moderate RV dilation in 60.7% of the patients and severe pulmonary valve regurgitation in 82.3%. Ten patients underwent additional TVR. Indication was purely based on annular dilation (>40 mm), independent from the degree of tricuspid insufficiency. Periprocedural data of both groups did not differ significantly. However, ICU stay was significantly increased in patients who underwent additional TVR (P=0.0420) and these patients developed more complications (P=0.0407) while postoperative echography showed the same recovery of the RV function and diameters, independent of concomitant TVR.
CONCLUSIONS CONCLUSIONS
In grown-ups with congenital heart disease surgical PVR with or without TVR is a safe procedure with good short-term outcomes. As the RV remodels after volume reduction, indication for concomitant TVR should be restrictive.

Identifiants

pubmed: 29786408
pii: S0021-9509.18.10385-5
doi: 10.23736/S0021-9509.18.10385-5
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

268-273

Auteurs

Sabrina Lueck (S)

Department of Cardiothoracic Surgery, Muenster University Hospital, Muenster, Germany - sabrina.lueck@ukmuenster.de.

Eike Bormann (E)

Institute of Biostatistics and Clinical Research, Muenster University Hospital, Muenster, Germany.

Kathrin Rellensmann (K)

Department of Cardiothoracic Surgery, Muenster University Hospital, Muenster, Germany.

Sven Martens (S)

Department of Cardiothoracic Surgery, Muenster University Hospital, Muenster, Germany.

Andreas Rukosujew (A)

Department of Cardiothoracic Surgery, Muenster University Hospital, Muenster, Germany.

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Classifications MeSH