Clinical routine use of virtual monochromatic datasets based on spectral CT in patients with hypervascularized abdominal tumors - evaluation of effectiveness and efficiency.


Journal

Acta radiologica (Stockholm, Sweden : 1987)
ISSN: 1600-0455
Titre abrégé: Acta Radiol
Pays: England
ID NLM: 8706123

Informations de publication

Date de publication:
Apr 2019
Historique:
pubmed: 29 6 2018
medline: 9 4 2019
entrez: 29 6 2018
Statut: ppublish

Résumé

Virtual monochromatic images (VMI) generated using spectral computed tomography (CT) are promising recently available tools to improve diagnostic performance in oncologic patients. To investigate if virtual monochromatic datasets are suitable for clinical routine use in patients with hypervascularized abdominal tumors. A total of 41 patients with hypervascularized hepatocellular carcinoma (HCC), renal cell carcinoma (RCC), or neuroendocrine tumors (NET) were enrolled in the study; 451 CT series were analyzed. In an intra-individual study design, virtual monochromatic datasets of the arterial phase of each scan were computed. Image quality was assessed objectively by determining signal-to-noise ratio (SNR) and contrast-to-noise ratios (CNR) and subjectively by using five-point Likert-scales. The volume CT dose index (CTDI Intra-individual comparison of the spectral mode in the arterial phase with the portal venous phase revealed no significant increase in the applied dose. SNR, CNR In clinical practice, the use of low energy VMI improved diagnostic confidence without a significant increase in dose. The main disadvantage is a decrease in efficiency due to longer reading times.

Sections du résumé

BACKGROUND BACKGROUND
Virtual monochromatic images (VMI) generated using spectral computed tomography (CT) are promising recently available tools to improve diagnostic performance in oncologic patients.
PURPOSE OBJECTIVE
To investigate if virtual monochromatic datasets are suitable for clinical routine use in patients with hypervascularized abdominal tumors.
MATERIAL AND METHODS METHODS
A total of 41 patients with hypervascularized hepatocellular carcinoma (HCC), renal cell carcinoma (RCC), or neuroendocrine tumors (NET) were enrolled in the study; 451 CT series were analyzed. In an intra-individual study design, virtual monochromatic datasets of the arterial phase of each scan were computed. Image quality was assessed objectively by determining signal-to-noise ratio (SNR) and contrast-to-noise ratios (CNR) and subjectively by using five-point Likert-scales. The volume CT dose index (CTDI
RESULTS RESULTS
Intra-individual comparison of the spectral mode in the arterial phase with the portal venous phase revealed no significant increase in the applied dose. SNR, CNR
CONCLUSION CONCLUSIONS
In clinical practice, the use of low energy VMI improved diagnostic confidence without a significant increase in dose. The main disadvantage is a decrease in efficiency due to longer reading times.

Identifiants

pubmed: 29950111
doi: 10.1177/0284185118786077
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

425-432

Auteurs

Georg Böning (G)

Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Felix Feldhaus (F)

Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Sebastian Adelt (S)

Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Johannes Kahn (J)

Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Uli Fehrenbach (U)

Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Florian Streitparth (F)

Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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Classifications MeSH