Medication related osteonecrosis of the jaw in osteoporotic
Journal
Dento maxillo facial radiology
ISSN: 0250-832X
Titre abrégé: Dentomaxillofac Radiol
Pays: England
ID NLM: 7609576
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
pubmed:
29
6
2018
medline:
8
8
2020
entrez:
29
6
2018
Statut:
ppublish
Résumé
To explore whether differences exist in the clinical and radiographic presentation of oncologic We retrospectively assessed panoramic radiographs and CBCT examinations of 70 MRONJ patients receiving antiresorptive medications for the management of either osteoporosis or bone malignancy. Radiographic features of MRONJ were documented and categorized according to severity. A composite radiographic index (CRI) was constructed to account for the heterogeneity in radiographic manifestations of MRONJ and further stratify extent of osseous changes. Patients with osteoporosis were mostly older females and presented more frequently with Stage 2 MRONJ, while patients with malignancy were equally distributed between males and females, and presented mostly with Stage 1 MRONJ. Most MRONJ lesions in oncologic patients occurred in the mandible, whereas the maxilla and mandible were equally affected in osteoporotic patients. Patients with minimal radiographic changes (low CRI score) often presented with MRONJ in dentate areas, while most patients in medium and high CRI groups presented with MRONJ after recent tooth extraction. The low CRI group consisted of primarily oncologic patients, while osteoporotic Our data identify differences in the MRONJ appearance of patients with osteoporosis
Identifiants
pubmed: 29952657
doi: 10.1259/dmfr.20180128
pmc: PMC6398905
doi:
Substances chimiques
Bone Density Conservation Agents
0
Types de publication
Journal Article
Langues
eng
Pagination
20180128Subventions
Organisme : NIDCR NIH HHS
ID : R01 DE019465
Pays : United States
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