Banff Lung Report: Current knowledge and future research perspectives for diagnosis and treatment of pulmonary antibody-mediated rejection (AMR).
Allografts
Antibodies
/ immunology
Complement C4
/ immunology
Gene Expression Profiling
Graft Rejection
/ immunology
HLA Antigens
/ immunology
Humans
Immunohistochemistry
Isoantibodies
/ immunology
Lung
/ immunology
Lung Transplantation
Peptide Fragments
/ immunology
Societies, Medical
Tissue Donors
Transplantation, Homologous
alloantibody
classification systems: Banff classification
clinical research/practice
histocompatibility
lung (allograft) function/dysfunction
lung transplantation/pulmonology
microarray/gene array
pathology/histopathology
rejection: antibody-mediated (ABMR)
Journal
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
ISSN: 1600-6143
Titre abrégé: Am J Transplant
Pays: United States
ID NLM: 100968638
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
received:
05
02
2018
revised:
19
06
2018
accepted:
19
06
2018
pubmed:
30
6
2018
medline:
17
4
2020
entrez:
30
6
2018
Statut:
ppublish
Résumé
The Lung session of the 2017 14th Banff Foundation for Allograft Pathology Conference, Barcelona focused on the multiple aspects of antibody-mediated rejection (AMR) in lung transplantation. Multidimensional approaches for AMR diagnosis, including classification, histological and immunohistochemical analysis, and donor- specific antibody (DSA) characterization with their current strengths and limitations were reviewed in view of recent research. The group also discussed the role of tissue gene expression analysis in the context of unmet needs in lung transplantation. The current best practice for monitoring of AMR and the therapeutic approach are summarized and highlighted in this report. The working group reached consensus of the major gaps in current knowledge and focused on the unanswered questions regarding pulmonary AMR. An important outcome of the meeting was agreement on the need for future collaborative research projects to address these gaps in the field of lung transplantation.
Identifiants
pubmed: 29956477
doi: 10.1111/ajt.14990
pii: S1600-6135(22)08895-5
doi:
Substances chimiques
Antibodies
0
Complement C4
0
HLA Antigens
0
Isoantibodies
0
Peptide Fragments
0
Types de publication
Congress
Langues
eng
Sous-ensembles de citation
IM
Pagination
21-31Informations de copyright
© 2018 The American Society of Transplantation and the American Society of Transplant Surgeons.