Congestive heart failure among children with acute leukemia: a population-based matched cohort study.
Adolescent
Child
Child, Preschool
Combined Modality Therapy
Female
Heart Failure
/ epidemiology
Humans
Incidence
Infant
Infant, Newborn
Leukemia, Myeloid, Acute
/ complications
Male
Population Surveillance
Precursor Cell Lymphoblastic Leukemia-Lymphoma
/ complications
Retrospective Studies
Risk Factors
Treatment Outcome
ALL
AML
Cardiotoxicity after cancer therapy
anthracycline-related cardiotoxicity
congestive heart failure
irradiation
Journal
Leukemia & lymphoma
ISSN: 1029-2403
Titre abrégé: Leuk Lymphoma
Pays: United States
ID NLM: 9007422
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
pubmed:
4
7
2018
medline:
21
3
2020
entrez:
4
7
2018
Statut:
ppublish
Résumé
The purpose was to describe the incidence and risk factors of congestive heart failure (CHF) among children with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). We included 2053 children (≤18 years) with first primary ALL and AML diagnosed 1992-2010 and registered in the Pediatric Oncology Group of Ontario Networked Information System. We identified CHF events through linked administrative databases. At 10 years, the cumulative incidence of CHF was 1.7% in ALL and 7.5% in AML. Factors associated with CHF in ALL were female gender, age <1 year at cancer diagnosis, irradiation and cumulative anthracycline dose ≥250 mg/m
Identifiants
pubmed: 29966479
doi: 10.1080/10428194.2018.1474522
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM