Understanding the management of patients with head injury taking warfarin: who should we scan and when? Lessons from the AHEAD study.


Journal

Emergency medicine journal : EMJ
ISSN: 1472-0213
Titre abrégé: Emerg Med J
Pays: England
ID NLM: 100963089

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 12 03 2018
revised: 10 07 2018
accepted: 16 07 2018
pubmed: 2 8 2018
medline: 14 6 2019
entrez: 2 8 2018
Statut: ppublish

Résumé

Anticoagulated patients represent an important and increasing proportion of the patients with head trauma attending the ED, but there is no international consensus for their appropriate investigation and management. International guidelines vary and are largely based on a small number of studies, which provide poor-quality evidence for the management of patients taking warfarin. This article provides an overview of the clinical research evidence for CT scanning head-injured patients taking warfarin and a discussion of interpretation of risk and acceptable risk. We aim to provide shop floor clinicians with an understanding of the limitations of the evidence in this field and the limitations of applying 'one-size-fits-all' guidelines to individual patients. There is good evidence for a more selective scanning approach to patients with head injuries taking warfarin than is currently recommended by most guidelines. Specifically, patients without any head injury-related symptoms and GCS score 15 have a reduced risk of adverse outcome and may not need to be scanned. We argue that there is evidence to support an individualised approach to decision to CT scan in mild head injuries on warfarin and that clinicians should feel able to discuss risks with patients and sometimes decide not to scan.

Identifiants

pubmed: 30065073
pii: emermed-2018-207621
doi: 10.1136/emermed-2018-207621
doi:

Substances chimiques

Anticoagulants 0
Warfarin 5Q7ZVV76EI

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

47-51

Informations de copyright

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Suzanne M Mason (SM)

Centre for Urgent and Emergency Care Research, School of Health and Related Research, University of Sheffield, Sheffield, UK.
Northern General Hospital, Sheffield Teaching Hospitals, Sheffield, UK.

Rachel Evans (R)

Centre for Urgent and Emergency Care Research, School of Health and Related Research, University of Sheffield, Sheffield, UK.
Northern General Hospital, Sheffield Teaching Hospitals, Sheffield, UK.

Maxine Kuczawski (M)

Centre for Urgent and Emergency Care Research, School of Health and Related Research, University of Sheffield, Sheffield, UK.

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