Efficacy of Intralesional Steroid Injection in Small Benign Vocal Fold Lesions.
Benign vocal cord lesions
Intralesional steroids
Methylprednisolone
Microlaryngeal surgery
Small vocal cord lesions
Small vocal polyp
Journal
Journal of voice : official journal of the Voice Foundation
ISSN: 1873-4588
Titre abrégé: J Voice
Pays: United States
ID NLM: 8712262
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
30
10
2017
accepted:
12
04
2018
pubmed:
6
8
2018
medline:
15
2
2020
entrez:
6
8
2018
Statut:
ppublish
Résumé
The present study was conducted to study the efficacy of intralesional steroid (ILS) injection in small benign vocal fold lesions and compare the outcomes with microlaryngeal surgery in terms of improvement in symptoms and reduction in lesion size. The current randomized control trial was conducted in the Department of Otolaryngology at the Postgraduate Institute of Medical Education and Research in Chandigarh between 2014 and 2015. The clinical diagnosis was based on appearance of the lesion during endoscopy and the mucosal vibration pattern. Subjects with lesions of size less than or equal to 5 mm were included. A total of 29 subjects were included in the study and 15 (nine men and six women) of them were randomized to receive ILS injection. Fourteen (13 men and one woman) were randomized to the second group to receive initial microlaryngeal surgery. We noted significant reduction in the size of the lesion among subjects undergoing ILS injection at 12 weeks (1.11 + 1.45 mm) as compared to baseline (2.63 + 1.28 mm) with no recurrence. ILSs are effective in reducing size of lesion and also improve acoustic parameters, perceptual analysis, and grade of dysphonia in patients presenting with small benign vocal cord lesions.
Identifiants
pubmed: 30077419
pii: S0892-1997(17)30512-X
doi: 10.1016/j.jvoice.2018.04.008
pii:
doi:
Substances chimiques
Anti-Inflammatory Agents
0
Methylprednisolone Acetate
43502P7F0P
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
767-772Informations de copyright
Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.