Efficacy of Intralesional Steroid Injection in Small Benign Vocal Fold Lesions.


Journal

Journal of voice : official journal of the Voice Foundation
ISSN: 1873-4588
Titre abrégé: J Voice
Pays: United States
ID NLM: 8712262

Informations de publication

Date de publication:
Sep 2019
Historique:
received: 30 10 2017
accepted: 12 04 2018
pubmed: 6 8 2018
medline: 15 2 2020
entrez: 6 8 2018
Statut: ppublish

Résumé

The present study was conducted to study the efficacy of intralesional steroid (ILS) injection in small benign vocal fold lesions and compare the outcomes with microlaryngeal surgery in terms of improvement in symptoms and reduction in lesion size. The current randomized control trial was conducted in the Department of Otolaryngology at the Postgraduate Institute of Medical Education and Research in Chandigarh between 2014 and 2015. The clinical diagnosis was based on appearance of the lesion during endoscopy and the mucosal vibration pattern. Subjects with lesions of size less than or equal to 5 mm were included. A total of 29 subjects were included in the study and 15 (nine men and six women) of them were randomized to receive ILS injection. Fourteen (13 men and one woman) were randomized to the second group to receive initial microlaryngeal surgery. We noted significant reduction in the size of the lesion among subjects undergoing ILS injection at 12 weeks (1.11 + 1.45 mm) as compared to baseline (2.63 + 1.28 mm) with no recurrence. ILSs are effective in reducing size of lesion and also improve acoustic parameters, perceptual analysis, and grade of dysphonia in patients presenting with small benign vocal cord lesions.

Identifiants

pubmed: 30077419
pii: S0892-1997(17)30512-X
doi: 10.1016/j.jvoice.2018.04.008
pii:
doi:

Substances chimiques

Anti-Inflammatory Agents 0
Methylprednisolone Acetate 43502P7F0P

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

767-772

Informations de copyright

Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

Auteurs

Anurag Snehi Ramavat (AS)

Department of Otorhinolaryngology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Electronic address: ramavatanu@gmail.com.

Harsimran Tiwana (H)

Department of Otorhinolaryngology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Nagamani Banumathy (N)

Department of Otorhinolaryngology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Jaimanti Bakshi (J)

Department of Otorhinolaryngology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Naresh Panda (N)

Department of Otorhinolaryngology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Ashish Goel (A)

Department of Medicine, University College of Medical Sciences, Delhi, India.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH