Comment diagnostiquer une insuffisance surrénalienne ?

Un test de stimulation à l'ACTH et des dosages hormonaux sont utilisés.

Quels tests pour évaluer une maladie auto-immune ?

Des tests sanguins comme les anticorps antinucléaires (ANA) sont effectués.

Comment confirmer une allergie ?

Des tests cutanés ou des dosages d'IgE spécifiques peuvent être réalisés.

Quels examens pour une inflammation chronique ?

Des analyses sanguines et des imageries comme l'IRM peuvent être nécessaires.

Comment diagnostiquer une pneumonie ?

Une radiographie thoracique et des cultures de crachats sont souvent utilisées.

Quels sont les effets secondaires courants de la prednisolone ?

Les effets incluent prise de poids, insomnie, et troubles gastro-intestinaux.

Quels symptômes indiquent une réaction allergique ?

Des démangeaisons, éruptions cutanées, ou gonflements peuvent survenir.

Comment reconnaître une infection opportuniste ?

Des symptômes comme fièvre, fatigue et douleurs peuvent indiquer une infection.

Quels signes d'une hyperglycémie ?

Les signes incluent soif excessive, urination fréquente et fatigue.

Quels symptômes d'une ostéoporose ?

Des douleurs osseuses et des fractures fréquentes peuvent être des signes.

Comment prévenir les infections sous traitement ?

Éviter les foules, se laver les mains et se faire vacciner sont essentiels.

Quelles mesures pour éviter l'ostéoporose ?

Une alimentation riche en calcium et de l'exercice régulier sont recommandés.

Comment réduire le risque de diabète ?

Maintenir un poids santé et une alimentation équilibrée aide à prévenir le diabète.

Quelles précautions pour les patients allergiques ?

Éviter les allergènes connus et avoir un plan d'urgence en cas de réaction.

Comment prévenir les effets secondaires de la prednisolone ?

Des contrôles réguliers et une bonne hygiène de vie peuvent aider.

Comment la prednisolone est-elle administrée ?

Elle peut être prise par voie orale, injectable ou en inhalation selon la condition.

Quels sont les traitements alternatifs à la prednisolone ?

Des anti-inflammatoires non stéroïdiens (AINS) ou des immunosuppresseurs peuvent être utilisés.

Comment gérer les effets secondaires de la prednisolone ?

Des ajustements de dose et des médicaments complémentaires peuvent aider.

Quelle est la durée du traitement par prednisolone ?

La durée dépend de la maladie, souvent de quelques jours à plusieurs mois.

Comment arrêter la prednisolone en toute sécurité ?

Un sevrage progressif est recommandé pour éviter des effets indésirables.

Quelles sont les complications possibles de la prednisolone ?

Les complications incluent l'ostéoporose, le diabète et les infections.

Comment gérer une infection opportuniste ?

Un traitement antibiotique et un suivi médical sont nécessaires.

Quels risques de troubles psychologiques ?

Des troubles comme l'anxiété et la dépression peuvent survenir sous traitement.

Comment prévenir les complications cardiovasculaires ?

Un mode de vie sain et un suivi régulier de la pression artérielle sont cruciaux.

Quels signes d'une réaction sévère au traitement ?

Des symptômes comme des difficultés respiratoires ou un gonflement du visage nécessitent une attention immédiate.

Quels facteurs augmentent le risque d'ostéoporose ?

L'âge, le sexe féminin, et une faible consommation de calcium sont des facteurs de risque.

Comment le diabète influence-t-il le traitement ?

Le diabète peut aggraver les effets secondaires de la prednisolone, nécessitant un suivi accru.

Quels sont les risques liés à l'âge avancé ?

Les personnes âgées sont plus susceptibles de développer des complications sous traitement.

Comment le tabagisme affecte-t-il le traitement ?

Le tabagisme peut augmenter le risque d'infections et d'autres complications.

Quels antécédents médicaux sont préoccupants ?

Des antécédents de maladies cardiovasculaires ou d'ulcères gastriques sont préoccupants.

Prednisolone - Informations médicales vérifiées

Oral prednisolone suppresses skin inflammation in a healthy volunteer imiquimod challenge model.

2023

DOI: 10.3389/fimmu.2023.1197650 PMID: 37545524

Imiquimod (IMQ) is a topical agent that induces local inflammation...

Humans Imiquimod Blister Healthy Volunteers Dermatitis +3 autres

Prednisolone Versus Colchicine for Acute Gout in Primary Care (COPAGO): protocol for a two-arm multicentre, pragmatic, prospective, randomized, double-blind, controlled clinical trial of prednisolone and colchicine for non-inferiority with a parallel group design.

05 Oct 2023

DOI: 10.1186/s13063-023-07666-6 PMID: 37798801

Gout is the most common form of rheumatic disease in which monosodium urate crystals are deposited in the joints followed by acute inflammatory reactions. There are various approved drugs that can be ... This pragmatic, prospective, double-blind, double-dummy, parallel-group, randomized, non-inferiority trial investigates whether prednisolone (intervention) is non-inferior to treatment with colchicine... This trial will provide evidence on the effectiveness of pain reduction and side effects of colchicine and prednisolone in acute gout in primary care.... ClinicalTrials.gov Identifier: NCT05698680 first posted on January 26, 2023 (retrospectively registered). URL of trial registry record: https://clinicaltrials.gov/study/NCT05698680....

Adult Humans Colchicine Prednisolone Prospective Studies +8 autres

Development and optimization of an in-house heterologous ELISA for detection of prednisolone drug in enzyme conjugates using spacers.

2023

DOI: 10.3389/fimmu.2023.1200328 PMID: 37675116

The introduction of spacers in coating steroid protein complexes and/or enzyme conjugates or immunogens is known to exert an influence on the sensitivity of steroid enzyme immunoassays. We investigate...

Humans Enzyme-Linked Immunosorbent Assay Antibodies Immunoenzyme Techniques Prednisolone

Effects of prednisolone tapering on effectiveness of infliximab in patients with ulcerative colitis: data from a retrospective cohort.

07 May 2024

DOI: 10.1136/bmjgast-2024-001343 PMID: 38719549

The influence of concomitant prednisolone on clinical outcomes and safety in infliximab-treated ulcerative colitis (UC) patients is unknown.... A retrospective cohort study was performed, including 147 UC patients treated with infliximab at a tertiary inflammatory bowel disease (IBD) centre. Primary outcome was corticosteroid-free clinical re... There was no overall association between prednisolone exposure or no exposure and CFCR at weeks 14 or 52 of infliximab. The proportion of patients with C reactive protein ≤5 mg/L was higher in the sta... In UC patients with limited disease burden, prednisolone did not affect effectiveness of infliximab. However, patients with increased disease burden seem to benefit from corticosteroid combination the...

Humans Colitis, Ulcerative Infliximab Retrospective Studies Prednisolone +12 autres

Single- versus Divided-Dose Prednisolone for the First Episode of Nephrotic Syndrome in Children: An Open-Label RCT.

01 10 2023

DOI: 10.2215/CJN.0000000000000216 PMID: 37335578

Early morning single-dose prednisolone has a hypothetical advantage of less hypothalamic-pituitary-adrenal (HPA) axis suppression, but lack of robust evidence has resulted in variation in practice, wi... Sixty children with first episode of nephrotic syndrome were randomized (1:1) to receive prednisolone (2 mg/kg per day), either as single or two divided doses for 6 weeks, followed by single alternati... Four children (single=1 and divided dose=3) did not attend the Short Synacthen Test and were hence excluded from analysis. Remission was induced in all, and no relapse postremission was noted during t... Among children with first episode of nephrotic syndrome, single-dose and/or divided-dose prednisolone were equally effective in inducing remission with similar relapse rates, but single dose had less ... CTRI/2021/11/037940.... This article contains a podcast at https://dts.podtrac.com/redirect.mp3/www.asn-online.org/media/podcast/CJASN/2023_10_09_CJN0000000000000216.mp3....

Child Humans Prednisolone Nephrotic Syndrome Glucocorticoids +3 autres

In RA, use of systemic glucocorticoids ≥5 mg/d (prednisolone-equivalent) was linked to MACE at 8.7 y.

Nov 2023

DOI: 10.7326/J23-0082 PMID: 37931264

So H, Lam TO, Meng H, et al....

Humans Glucocorticoids Prednisolone Arthritis, Rheumatoid Antirheumatic Agents

Transport of prednisolone, cortisone, and triamcinolone acetonide in agricultural soils: Sorption isotherms, transport dynamics, and field-scale simulation.

15 Dec 2023

DOI: 10.1016/j.envres.2023.117287 PMID: 37813136

The occurrence of glucocorticoids (GCs) in agricultural soils has raised concerns due to their high polarity, widespread biological effects in vertebrates, and their potential to disrupt vital process...

Soil Triamcinolone Acetonide Cortisone Prednisolone Soil Pollutants +4 autres

Prednisolone administration monitored by postoperative stool color achieves high jaundice clearance after laparoscopic portoenterostomy for biliary atresia.

20 Nov 2023

DOI: 10.1007/s00383-023-05580-1 PMID: 37985521

Stool color (SC) for monitoring prednisolone use in biliary atresia (BA) patients after laparoscopic portoenterostomy (LPE) was reviewed.... Subjects were 47 post-LPE BA patients given a reducing dose course of intravenous prednisolone. The course started at 4 mg/kg/day and gradually reduced, ultimately reaching a final total dose (TD) of ... JC was achieved in 38/47 (80.9%) LPE cases and 4/6 redos to give an overall JC rate (JCR) of 42/47 (89.4%). Outcomes after one course (n = 5; JCR: 80.0%; median TD: 30.0 mg/kg, interquartile range [IQ... Indications for repeat prednisolone and timing of redo/LTx based on SC monitoring appeared effective based on high JCR and successful redo/LTx.... III....

Humans Infant Biliary Atresia Prednisolone Portoenterostomy, Hepatic +4 autres

Prednisolone 20 mg vs 40 mg in complex regional pain syndrome type I: A randomized controlled trial.

Jul 2023

DOI: 10.1016/j.jocn.2023.05.017 PMID: 37257216

High dose of corticosteroid has been found beneficial in complex regional pain syndrome type I (CRPS-I). We report the efficacy and safety of prednisolone 20 mg versus 40 mg in CRPS-I in an open label... The patients with CRPS-I of the shoulder joint with a CRPS score of ≥8 were included. Their demographic details, comorbidities, and underlying etiology were noted. The severity of CRPS was assessed us... Fifty patients were included, and their baseline characteristics were comparable. At one month, all the patients had >50% reduction in the VAS score. The effect size was 0.38 (95% CI 0.93-0.20; p = 0.... The efficacy of prednisolone 20 mg is not inferior to 40 mg in CRPS-I, and is safe in diabetic patients.... This is an open label randomized controlled trial with small sample size without a placebo arm....

Humans Complex Regional Pain Syndromes Reflex Sympathetic Dystrophy Prednisolone Pain Measurement

Combination of Prednisolone and Calcineurin Inhibitors Prevents Lung Function Decline in Patients with Anti-aminoacyl-tRNA Synthetase Antibody-Positive Polymyositis/Dermatomyositis.

30 Nov 2023

DOI: 10.2739/kurumemedj.MS6912002 PMID: 37544752

Anti-aminoacyl-tRNA synthetase antibody-positive polymyositis/dermatomyositis-associ ated interstitial lung disease (ARS-ILD) has a good prognosis, with few cases progressing to respiratory failure. T... We retrospectively studied 49 patients with ARS-ILD treated at Kurume University Hospital Hospital between 2000 and 2018. We followed 30 patients for more than 2 years after prednisolone (PSL) therapy... After treatment for 24 months, no significant differences were noted between clinical parameters and improvement in forced vital capacity (FVC), %FVC, % carbon monoxide diffusing capacity/alveolar vol... Compared with PSL monotherapy, combining PSL and CNI showed greater mitigation of %FVC decline. The time from onset of ARS-ILD to the first visit is critical for preventing a decline in lung function,...

Humans Dermatomyositis Calcineurin Inhibitors Amino Acyl-tRNA Synthetases Retrospective Studies +4 autres

Prednisolone : Questions médicales fréquentes

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Méthylprednisolone

Prednimustine

Acétate de méthylprednisolone

Méthylprednisolone succinate

Auteurs principaux

Sources (179 au total)