Oral prednisolone suppresses skin inflammation in a healthy volunteer imiquimod challenge model.


Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2023
Historique:
received: 31 03 2023
accepted: 20 06 2023
medline: 8 8 2023
pubmed: 7 8 2023
entrez: 7 8 2023
Statut: epublish

Résumé

Imiquimod (IMQ) is a topical agent that induces local inflammation

Identifiants

pubmed: 37545524
doi: 10.3389/fimmu.2023.1197650
pmc: PMC10400434
doi:

Substances chimiques

Imiquimod P1QW714R7M
Prednisolone 9PHQ9Y1OLM
Anti-Inflammatory Agents 0

Types de publication

Randomized Controlled Trial Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1197650

Informations de copyright

Copyright © 2023 Assil, Buters, Hameeteman, Hallard, Treijtel, Niemeyer – Van der Kolk, de Kam, Florencia, Prens, van Doorn, Rissmann, Klarenbeek, Jansen and Moerland.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Blood. 2007 Aug 1;110(3):946-53
pubmed: 17446350
Dose Response. 2018 Jul 25;16(3):1559325818783932
pubmed: 30083083
Br J Clin Pharmacol. 2022 Feb;88(2):680-690
pubmed: 34293819
Br J Dermatol. 2007 Dec;157 Suppl 2:8-13
pubmed: 18067624
Skin Res Technol. 2012 May;18(2):225-31
pubmed: 22092854
Clin Transl Sci. 2018 Nov;11(6):607-615
pubmed: 29768709
Annu Rev Pharmacol Toxicol. 2015;55:55-74
pubmed: 25292425
Clin Pharmacokinet. 1979 Mar-Apr;4(2):111-28
pubmed: 378499
J Immunol. 2009 May 1;182(9):5836-45
pubmed: 19380832
Br J Clin Pharmacol. 1980 Nov;10(5):503-8
pubmed: 7437263
J Interferon Cytokine Res. 1995 Jun;15(6):537-45
pubmed: 7553223
Mol Cell Biol. 1995 Apr;15(4):2207-18
pubmed: 7534379
Clin Transl Sci. 2020 May;13(3):573-579
pubmed: 32043302
Sci Rep. 2019 Aug 21;9(1):12217
pubmed: 31434955
Eur J Immunol. 2013 Dec;43(12):3138-46
pubmed: 24254490
Clin Pharmacol Ther. 2022 Apr;111(4):964-971
pubmed: 34935141
Eur J Endocrinol. 2012 Mar;166(3):459-67
pubmed: 22180452
Clin Pharmacol Ther. 1979 May;25(5 Pt 1):571-8
pubmed: 436359
BMJ. 2014 Jun 06;348:g3727
pubmed: 24906716

Auteurs

Salma Assil (S)

Centre for Human Drug Research, Leiden, Netherlands.
Division of Biotherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, Netherlands.

Thomas P Buters (TP)

Centre for Human Drug Research, Leiden, Netherlands.
Leiden University Medical Centre, Leiden, Netherlands.
Department of Dermatology Erasmus Medical Centre, Rotterdam, Netherlands.

Pieter W Hameeteman (PW)

Centre for Human Drug Research, Leiden, Netherlands.

Charlie Hallard (C)

Centre for Human Drug Research, Leiden, Netherlands.

Nicoline Treijtel (N)

Centre for Human Drug Research, Leiden, Netherlands.

Tessa Niemeyer-Van der Kolk (T)

Centre for Human Drug Research, Leiden, Netherlands.

Marieke L de Kam (ML)

Centre for Human Drug Research, Leiden, Netherlands.

Edwin F I I I Florencia (EFIII)

Department of Dermatology Erasmus Medical Centre, Rotterdam, Netherlands.

Errol P Prens (EP)

Department of Dermatology Erasmus Medical Centre, Rotterdam, Netherlands.

Martijn B A van Doorn (MBA)

Department of Dermatology Erasmus Medical Centre, Rotterdam, Netherlands.

Robert Rissmann (R)

Centre for Human Drug Research, Leiden, Netherlands.
Division of Biotherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, Netherlands.
Leiden University Medical Centre, Leiden, Netherlands.

Naomi B Klarenbeek (NB)

Centre for Human Drug Research, Leiden, Netherlands.
Leiden University Medical Centre, Leiden, Netherlands.

Manon A A Jansen (MAA)

Centre for Human Drug Research, Leiden, Netherlands.

Matthijs Moerland (M)

Centre for Human Drug Research, Leiden, Netherlands.
Leiden University Medical Centre, Leiden, Netherlands.

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Classifications MeSH